• Journal of the Korea Society of Computer and Information
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• v.25 no.6
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• pp.165-170
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• 2020

In this paper, it was confirmed that scopoletin inhibits neuroinflammation induced by amyloid beta oligomer (Aβ_1-42) in microglial BV-2. The mechanisms of inflammatory cytokines and inflammatory mediators by scopoletin were identified. Alzheimer's disease is the most common neurodegenerative disease, but it is a disease whose specific etiology is unknown, and many studies are trying to solve it. We first measured the cell viability with the CCK-8 assay method to confirm that scopoletin and Aβ_1-42 are toxic to BV-2 cells. Expression levels of interleukin 1 beta (IL-1β), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor-κB (NF-κB) in inflammatory reactions induced by Aβ_1-42 with western blot were analyzed. The ANOVA assay was used to compare protein expression differences between BV-2 cells treated with Aβ_1-42 alone and BV-2 cells pretreated with Aβ_1-42 and scopoletin. Therefore, this study suggested that scopoletin is worth developing as a neuroinflammatory protection agent for Alzheimer's disease in the future.

• Cross-Cultural Studies
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• v.41
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• pp.199-227
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• 2015

In the twenty-first century, one of the most controversial issues concerns neoliberal policies and its results. In particular, since the mid-1980s, the United States and international financial institutions have imposed their programs on Latin American countries. The result is a deepening social inequality in Latin America that puts an emphasis on financial stability instead of social security. Consequently, social inequality is worsened and an imbalance in income distribution took place. Because of the flexibility of labor, the middle class is destroyed. For the poor person deprived of the opportunity to rise, violence is a common occurrence in daily life. Thus, in this context, Eduardo Galeano raises the necessity of a critique concerning the values that neoliberalism regards as important. Furthermore, Galeano is also wary of the "militarization of neoliberalism." This is because the neoliberal multinationals motivate a war without borders under the guise of peace. Neo-liberal policies also contribute to environmental pollution. However, environmental vandalism, which happens in partnership with large and international organizations, is not readily apparent to the public because those perpetrators wore a "green mask." Hence, Galeano assiduously endeavors to undercover the false consciousness hiding behind the green mask. Thus, in brief summary, Galeano represents in his works a depiction about Latin America where violence often happens in daily life.

• Journal of Digital Convergence
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• v.16 no.12
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• pp.373-381
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• 2018

This study investigates convergent influence on TOEIC learning flow and its association with self efficacy, academic control and school resilience among health college students. Data collection was carried out using a self-administered questionnaire from May 1 to May 29, 2018 and the target was randomly selected 255 health college students in TOEIC class from college located in J city. TOEIC learning flow was positively correlated with self efficacy, academic control and school resilience. With the analysis of covariance structure, we could confirm relationship among self efficacy, academic control, school resilience and TOEIC learning flow. School resilience was more influential on TOEIC learning flow than self efficacy and academic control. The results of the study indicate that the efforts to manage these factors are required to increase TOEIC learning flow of health college students in TOEIC class. The results are expected to be used to develop TOEIC learning curriculum increasing the TOEIC learning flow among health college students in TOEIC class. In the following study, the survey about additional factors of influence on TOEIC learning flow will be needed.

• Journal of Dairy Science and Biotechnology
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• v.36 no.4
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• pp.208-219
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• 2018

Emergence of drug resistant strains of Salmonella enterica threatens milk processing and related dairy industries, thereby increasing the need for development of new anti-bacterials. Developments of antibacterial drugs are largely aimed to target the bacterial envelope, but screening their efficacy on bacterial envelope is laborious. This study presents a potential biosensor for envelope-specific stress in which a gfp reporter gene fused to spy gene encoding a periplasmic chaperone protein Spy (spheroplast protein y) that can sense envelope stress signals transduced by two major two-component signal transduction systems BaeSR and CpxAR in Salmonella enterica serovars Enteritidis and S. Gallinarum. Using spy-gfp operon fusions in S. Enterititis and S. Gallinarum, we found that spy transcription in both serovars was greatly induced when Salmonella cells were forming the spheroplast and were treated with ethanol or a membrane-disrupting antibiotic polymyxin B. These envelope stress-specific inductions of spy transcription were abrogated in mutant Salmonella lacking either BaeR or CpxR. Results illustrate that induction of Spy expression can be efficiently triggered by two-component signal transduction systems sensing envelope stress conditions, and thereby suggest that monitoring the spy transcription by spy-gfp operon fusions would be helpful to determine if developing antimicrobials can damage envelopes of S. Enteritidis and S. Gallinarum.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.24-24
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• 2019

DMZ 및 접경지역은 지난 60여 년간 인간의 간섭을 받지 않아 세계적으로 우수한 생태계의 보고이며, 백두대간, 도서연안과 함께 한반도 3대 핵심생태축의 하나로서 한반도생태계보전을 위한 가장 중요한 지역이다. 이러한 DMZ 및 접경지역에 대하여 국내적 중요성 인식 제고뿐만 아니라 국제적으로도 중요생물다양성지역(KBAs)으로서의 가치인식을 위해 IUCN에서 제시하는 평가기준을 검토하고 이의 기준을 적용하여 DMZ의 생물다양성에 대한 국제적 가치정도 판단 및 중요생물다양성지역(KBAs)으로서의 보전방안을 수립하고자 한다. 첫째, DMZ 일대를 대상으로 서식하는 자생식물의 분포지역을 파악하여 DMZ 및 접경지역의 식물상은 18과 139속 367종 1아종 44변종 10품종 422분류군으로, 총 138과 613속 1,517종 8아종 217변종 58품종으로 총 1,800분류군으로 확인되었다. 본 연구대상지의 동부지역에서 가장 많은 1,482분류군, 중부지역은 1,225분류군, 서부지역은 1,080분류군으로 가장 적은수의 식물이 확인되었다. 둘째, DMZ 및 접경지역을 대상으로 객관적이고 정량적인 방법을 통한 DMZ 및 접경지역의 중요생물다양성지역(KBAs) 지정기준을 적용하여 개느삼, 금강초롱, 모데미풀 3종을 중요생물다양성지역(KBAs) 후보종으로 선정하였다. 후보종별로 분포예측 결과 전체 면적 $5,270.5km^2$ 중요생물다양성지역(KBAs) 지정을 제안하였다. 셋째, 지정기준을 통하여 선정된 DMZ 및 접경지역에 서식하는 주요 식물에 대한 국제적 가치를 판단하여 우리나라 상황에 맞는 중요생물다양성지역(KBAs)을 적용함으로써 효과적인 관리방안으로 투명하고 체계화된 국제적 기준으로 해당 지역 내의 생물종 다양성을 지속가능하게 보호하기 위한 구체적인 방향 설정 및 관리를 위한 노력이 이루어질 수 있도록 유도 할 수 있다. 수집된 자료를 통하여 중요생물다양성지역(KBAs)에 적합한 종을 중심으로 보호구역을 지정하고 국내적으로 중요한 지역적 멸종위기종에 대한 적용을 추가적으로 진행하여 식물다양성이 중요한 지역의 보호를 위한 우선순위 및 구체적 접근계획을 수립할 수 있을 것으로 판단된다. 국가적인 차원에서 DMZ 및 접경지역의 지속적인 조사를 통하여 중요생물다양성지역(KBAs)기준 적용에 필요한 기초자료를 충분히 수집하고 국내 환경에 부합하는 중요생물다양성지역(KBAs)기준 적용을 통하여 꾸준히 재평가하여 후속연구의 발판을 마련하여야 한다.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.480-493
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• 2021

Since the generalized Hoek-Brown criterion (GHB) provides an efficient way of identifying its strength parameter values with the consideration of in-situ rock mass condition via Geological Strength Index (GSI), this criterion is recognized as one of the standard rock mass failure criteria in rock mechanics community. However, the nonlinear form of the GHB criterion makes its mathematical treatment inconvenient and limits the scope of its application. As an effort to overcome this disadvantage of the GHB criterion, the explicit approximate analytical equations for the minimum principal stress, which is associated with the maximum principal stress at failure, are formulated based on the Taylor polynomial approximation of the original GHB criterion. The accuracy of the derived approximate formula for the minimum principal stress is verified by comparing the resulting approximate minimum principal stress with the numerically calculated exact values. To provide an application example of the approximate formulation, the equivalent friction angle and cohesion for the expected plastic zone around a circular tunnel in a GHB rock mass are calculated by incorporating the formula for the approximate minimum principal stress. It is found that the simultaneous consideration of the values of mi, GSI and far-field stress is important for the accurate calculation of equivalent Mohr-Coulomb parameter values of the plastic zone.

• Korean Association of Arts Management
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• no.51
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• pp.191-219
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• 2019

Adoption of applicable law for the international trade of artworks is closely related to the results of lawsuits. Recently, starting with New York, the hub of the international artworks market, a modern, mixed-law is gradually being adopted more. It is difficult to designate an applicable law of an international trade of artworks through private laws regulations of relevant countries, and the public laws regulations must also be considered in relation to individual benefits and the public benefits to the relevant countries. With regards to the foreign relations issues, Korea's private international law embraces a so-called public order theory, and according to the Section 7 of the Act on the Private International Law and its enactment history, the compulsory provision, which seems appropriate for application to the corresponding matter, applies without regards to the selection of the applicable law. The Civil Act of Korea acknowledges bona fide acquisition of a cultural asset, in principle, if the Cultural Heritage Protection Act is not applicable. Moreover, a lost artwork is also a subject of bona fide acquisition; however, if the relevant artwork is either stolen or lost, the original owner has the right to demand the return of that artwork within 2 years of being stolen or lost according to the Section 250 of the Civil Act. Also, if the buyer purchased from a distributor specializing in the artworks, such as auction, open market or gallery, the buyer could request a compensation of the purchase price from the original owner, and if the buyer purchased through a private transaction, the buyer cannot demand a compensation of the purchase price and must return the artwork.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.401-401
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• 2020

최근 전 세계적으로 기후변화로 인한 자연재해가 빈번하게 발생하고 있으며, 우리나라 역시 해마다 가뭄과 홍수 등의 피해가 큰 실정이다. 특히 가뭄으로 인한 피해는 농업분야와 직결되어 있으며, 미래식량과 물안보에 영향을 미친다. 최근에는 국내 물관리일원화 정책에 따른 통합물관리 시행으로 수요관리에 의한 물이용 효율성이 물관리 기본원칙으로 포함되어 있어, 농업용수 분야의 물절약 필요성과 중요성은 더욱 증대되고 있는 실정이다. 농업농촌부문 가뭄대응 종합대책의 일환으로 2016년부터 농업용수 이용자 측면에서 물절약 실천을 유도하기 위한 물절약 교육 모델의 개발과 농업인 대상 시범교육이 실시되고 있으나 일부 지역에만 단발성 사업으로 제한적으로 추진되고 있는 실정이다. 따라서 물절약 교육 및 홍보사업을 보다 체계적이고 광법위하게 적용하여 농업 현장에서의 가시적인 물절약 성과를 도출하기 위한 노력이 요구된다. 이에 대한 일환으로 본 연구에서는 물절약 교육 콘텐트 개발 및 현장 교육에 반영하기 위하여 농업인 대상 물절약 의식과 행동실천 여부에 대해 조사를 실시해 보았다. 포항 및 영덕지역의 한국농어촌공사 관할지구 내 농업용수 이용자 중 수리시설감시원(이하 '수감원') 100여명을 대상으로 설문조사로 파악해 보았다. 설문에 참여한 수감원들은 대부분 65세 이상의 고령으로 농업에 오랜 기간 종사한 경험의 소유자로서 소규모 농업경영이 주를 이루었다. 대부분 농사기간동안 물부족 경험이 있었으며, 모내기 및 벼생육기 강우조건에 따라 물부족을 경험한 것으로 파악되었다. 이로 인해 설문 참여자들의 물절약 필요성에 대해서는 높은 공감대를 나타내었으며, 특히 농업인 대상 물절약 교육의 필요성에 대해서 매우 높은 공감대를 나타내었다. 농업인의 물과다 사용 및 물꼬관리 부실 등 필지단위 물관리 부실에 대해서도 상당히 인정하는 편이었으며, 이러한 농업인의 관행적인 물관리 행태에 대해서 변화를 유도할 수 있는 수리계조직 부활을 통한 농업인 물관리 직접 참여 등의 대안이 필요하다는 의견에 대해서도 긍정적이었다. 또한 농업인 용수이용에 대한 비용 부담에 대해서도 다소 긍정적인 의견도 제시되었다. 본 연구 결과로 농업인의 적극적인 물관리 및 물절약 참여를 이끌어 낼 수 있는 실현가능한 관련 제도 마련의 필요성과 체계적이고 지속적인 물절약 교육 및 홍보 정책 추진의 필요성이 제기된다.

• Journal of Korean Library and Information Science Society
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• v.54 no.4
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• pp.281-306
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• 2023

This study analyzed the legal deposit, acquisition, and donation status from 2020 to 2022, along with the deposit status of e-publications with issued ISBNs. Through this analysis, the study derived improvement measures to strengthen compliance with legal deposit obligations for domestic e-publications. The key findings are as follows: The collection methods were acquisition (57.07%), legal deposit (41.74%), and donation (1.19%). The file formats varied, including e-books (pdf, epub), webtoons (jpg), and audiobooks (mp3). Most e-publications collected were published from 2012 to 2022, with some from 1960 to 2011. Webtoons dominated acquired materials, while legal deposits mainly comprised e-books. Analyzing the status of e-publications with issued ISBNs, e-books (96.2%) were most common, with the literature field receiving the highest number of ISBNs. Most ISBNs were issued during 2020 to 2022. Looking at the top 10 publishers, the low legal deposit rate indicates the need for improvement. To address this, proposed improvement measures include enhancing publishers' awareness of legal deposits, strengthening incentives and sanctions, encouraging voluntary participation through transparent disclosure of the legal deposit status, and improving the accuracy of data in the ISBN issuance and deposit system.

• Journal of the Economic Geographical Society of Korea
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• v.10 no.3
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• pp.263-280
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• 2007

Recently, many cities and regions of the world attempt to promote cultural and arts activities in order to vitalize regional economies and strengthen local identity. Some old industrial cities of the advanced economies in particular often introduce cultural and arts activities in renovating obsolete urban infra-structure, revitalize urban economy, clean polluted urban environment, and advertise various development projects. A small Canadian city, Stratford, Ontario, has shown a spectacular success in such efforts. By hosting Shakespearian festivals every year since 1953, the theatre company, the Shakespearian Festival of Canada in Stratford, sells about 600 thousands tickets, attracting 2 million visitors to the area. With the festivals, the city became able to host a large cultural cluster composed of the theatre company, chef school, summer music festival, and Chicago Associates. The city has also able to maintain one of the most competent theatre companies in the North America.