• Journal of the Mineralogical Society of Korea
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• v.17 no.4
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• pp.309-325
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• 2004

The Cannington Ag-Pb-Zn deposit, northwest Queensland, Australia developed around the host rocks composing banded and migmatitic gneisses, sillimanite-garnet schist and amphibolite. Three crystal habits of sillimanite, gahnite (Zn-spinel) and garnet porphyroblasts occurred on the host rocks of the Cannington deposit could be used to delineate metamorphism that closely associated with Zn-mineralization in the deposit. Linkages the metamorphism to Zinc-mineralization is determined in four chemical systems, KFMASH (K$_2$O-FeO-MgO-Al$_2$O$_3$-SiO$_2$-$H_2O$), KFMASHTO (K$_2$O-FeO-MgO-Al$_2$O$_3$-SiO$_2$-$H_2O$-TiO$_2$-Fe$_2$O$_3$), NCKFMASH (Na$_2$O-CaO-K$_2$O-FeO-MgO-AlO$_3$-SiO$_2$-$H_2O$) and MnNCK-FMASH (MnO-Na$_2$O-CaO-K$_2$O-FeO-MgO-AlO$_3$-SiO$_2$-$H_2O$), using THERMOCALC program (version 3.1; Powell and Holland 1988). Partial melting in MnNCKFMASH and NCKFMASH systems occurs at lower temperature than in the KFMASH and KFMASHTO systems. The partial melting temperature decreases with increasing of Na/(Na+Ca+K) of the bulk rock compositions in the MnNCKFMASH system. The host rocks have melted ca 15 vol.% in the MnNCKFMASH system at peak metamorphic conditions (634$\pm$62$^{\circ}C$ and 4.8$\pm$1.3 kbar), but partial melting have not occurred in KFMASHTO system. Based on calculations of sillimanite isograd in different systems and sillimanite modal pro-portion, prismatic and rhombic sillimanite and gahnite porphyroblasts including prismatic sillimanite inclusion probably have resulted from pressure and temperature increasing through partial melting (from 550～$600^{\circ}C$, 2.0～3.0 kbar to 700～75$0^{\circ}C$, 5.0～7.0 kbar), furthermore have experienced N-S then W-E crustal shortening during D$_1$ and D$_2$ deformation. Consequently, Zinc mineralization related to gahnite growth occurred during D$_2$ and was redistributed and upgraded by partial melting and retrograde metamorphism into structural and rheological sites during shearing in D$_3$.

• The Journal of Society for e-Business Studies
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• v.7 no.2
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• pp.97-111
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• 2002

E-business curriculum needs to be developed reflecting requirements of the industry which involve a close relation with a job performed in the field, and a professional knowledge and an expert skill. In this paper, we present a method based on a market-oriented approach for developing an I-business curriculum. For the purpose, we analyze the opinion data resulting from the surveyed opinions of respondents working for I-business companies and evaluate the importance of each course being involved in the curriculum with respect to the job classification (e.g., Web planner, Web master, Web programmer, Web marketer, Web designer, Web PD), and then, complete a flow diagram considering precedence and relative difficulty among the selected courses. The E-business curriculum developed by the proposed method is useful to provide guidelines for determining courses required toward a desired job and for making a partial amendment of the curriculum.

• The Journal of Society for e-Business Studies
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• v.7 no.2
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• pp.113-128
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• 2002

This paper proposes a public oriented e-Marketplace that induces strategic coalition using database in which detail information about each firm is contained. A public oriented e-Marketplace links each firm through the type of Internet business model and constructs a trading community. We introduce a design methodology of public oriented e-Marketplace called as social network analysis. Social network analysis helps each firm's network easily visualized and completely modeled. Additionally, this paper tries to analyze the relationship among the level of competition, potential of strategic coalition, and financial performance. We demonstrate the firm to easily accept various strategic coalitions can make higher financial performance under the more competitive condition. This implies that strategic coalition through public oriented e-Marketplace provide the each firm with various opportunities.

• Toxicological Research
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• v.14 no.2
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• pp.205-209
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• 1998

To evaluate immunotoxicity of skin decontamination kit(SDK) newly-developed in Agency for Defense Development(ADD), delayed contact hypersensitivity (maximization) test and passive cutaneous anaphylaxis(PCA) test of SDK were performed and the results were compared with those of M 291. In maximization test, sensitization reaction was induced by id injection (2.5 mg / 0.1 $\textrm{m}{\ell}$/ guinea pig or 2.5 mg+CFA/0.1 $\textrm{m}{\ell}$/guinea pig) and topical application (2.5 mg/$\textrm{m}{\ell}$/guinea pig) with SDK or M291 at an interval of 1 week, and 2 weeks later, challenged by topical application with 25 mg/$\textrm{m}{\ell}$/guinea pig. SDK and M291 did not induce any reactions, showing 0 point of sensitization score and 0% of sensitization rate. In conclusion, it is suggested that SDK and M291 do not induce delayed contact hypersensitivity. In PCA test, rats were administered id with mouse anti-SDK serum and challenged iv with a mixture of antigen SDK and Evan's blue. SDK did not induce blue spots at the injection sites of both high (2.5 mg/mouse) and low (1.25 mg/mouse) dose-induced antisera. In contrast, BSA, positive control produced spots larger than 5 mm in diameter at the injection sites of BSA-induced antiserum up to $2^2$ ~ $2^4$dilution. In conclusion, it is suggested that SDK do not induce IgE production and is not a PCA-reaction inducer.

• Journal of Food Hygiene and Safety
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• v.24 no.3
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• pp.267-272
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• 2009

The trace element nutrient selenium discharges its well-known nutritional anti-tumor activity. Converging data from epidemiological, ecological and clinical studies have shown that selenium can decrease the risk for some types of human cancers, especially those of the prostate, lung, and colon. Mechanistic studies have indicated that selenium has many desirable attributes of chemoprevention targeting cancer cells through DNA single strand breaks, the induction of reactive oxygen species. However, there is no reports about the relationship between methylseleninic acid (MSeA), one of methylselenol metabolites and cell cycle arrest in LNCaP human prostate cancer cells. Our data showed that MSeA arrested G1/S pahse of cell cycle arrest and inhibited DNA synthesis in LNCaP cells and those cellular events by MSeA were due to the induction ofp27 protein which is a well-known cyclin-dependent kinase inhibitor. Taken together, cell cycle arrest occurred by MSeA may contribute to the growth-inhibition of prostate cancer cells.

• Toxicological Research
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• v.14 no.3
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• pp.453-457
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• 1998

In order to evaluate the mutagenic potential of Intralipidos produced by Greenmate cooperation. We performed Salmonella typhimurium reversion assay, chromosomal aberration test on chinese hamster ovarian cells and in vivo micronucleus assay using mouse bone marrow cells. In the reverse mutation test using Salmonella typhimurium TA98 and TA100, Intralipidos did not increase the number of revertant at any of the concentration tested in this study. Intralipidos did not increase the number of cells having structural or numberical chromosome aberration in cytogenetic test. In mouse micronucleus test, no significant increase were observed in the occurrence of micornucleated polychromatic erythrocytes in ICR male mice intraperitoneally administered with Intralipidos. These results indicate that Intralipidos has no genetic toxicity under these experimental conditions.

• Proceedings of the Petrological Society of Korea Conference
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• 2002.05a
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• pp.1-38
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• 2002

옥천변성대 서남부지역은 변성이질암의 광물조합을 기준으로 남동부부터 북서방향으로 흑운모대, 석류석대, 십자석대의 3개의 변성광물분대로 나누어진다. Oh et al. (1995a)의 연구에서 보고된 남정석들은 산출되지 않는 것이 확인되었고 변성도는 흑운모대에서 석류석대를 거쳐 십자석대로 갈수록 증가한다. 쥬라기 화강암 접촉부의 국부적인 변성암류에서는 화강암에 의한 접촉변성작용에 의해 형성된 홍주석과 규선석이 산출된다. 흑운모대의 변성 압력-온도는 4.2 - 5.1 kb, 400 - 500 $^{\circ}C$이다. 십자석대의 정누대구조를 가지는 석류석과 석류석안의 사장석, 흑운모, 금흥석, 일메나이트포유광물의 공생관계로 추정한 압력-온도 (석류석 주변부: 7.0 - 8.0 kb, 550 - 620 $^{\circ}C$； 석류석 중심부: 4.0 - 5.0 kb, 420 - 520 $^{\circ}C$) 및 십자석대 내에서 후퇴변성작용 및 접촉변성작용 받은 석류석 주변부에 기록된 압력-온도 조건(약 2.0 - 3.0kb, 450 - 55$0^{\circ}C$)과 함께 옥천변성대 서남부지역의 변성암류가 시계방향의 압력-온도 경로를 겪었음을 지시한다. 연구지역 내에서 정밀 기재된 단면들에 대한 퇴적환경을 종합하면 대체 적으로 남동부에서는 천해성 환경이 인지되나 북서쪽으로 갈수록 대륙사면을 거쳐 분지 중심의 환경으로 전이되는 경향을 보인다. 이러한 퇴적상의 공간적 분포는 분지의 남동쪽보다 북서쪽의 침강이 우세하였던 것으로 해석될 수 있으며, 이는 곧 분지가 형성될 때 반지구대 (half graben) 형태로 분지가 열개 (rifting) 되었음을 의미한다. 각 변성분대에서 채취한 변성이질암으로부터 측정된 K-Ar 과 40Ar/39Ar 흑운모와 백운모 연대들은 149 - 167 Ma에 집중된다. 그리고 각 변성분대에서 동일시료에 대한 K-Ar 과 40Ar/39Ar 연대들은 동일시기를 지시함으로 연대적인 신뢰성을 확인 할 수 있었다. 옥천변성대 서남부지역의 변성암류를 관입하는 2개의 괴상의 화강암과 1개의 엽리화강암에서 얻어진 백운모와 흑운모들의 K-Ar 연대는 모두 156 Ma이며 옥천변성대 서남부지역의 변성이 질암의 연대와 유사하다. 이는 연구지역의 변성암류와 화강암류는 40Ar/39Ar 과 K-Ar 계의 흑운모와 백운모의 폐쇄온도 (약 300 - 350 $^{\circ}C$) 까지 동시에 냉각된 사실을 지시한다. 각섬석 편암내의 각섬석들은 복잡한 40Ar/39Ar 연대를 보여주며 일부가 평형연대를 보여주지만 특별한 의미 부여가 힘들다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.04a
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• pp.30-30
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• 2018

한반도 고유 식물자원인 특산식물 물들메나무의 지리학적 분포 범위에 대한 고찰을 시도 하였으며, 이를 바탕으로 IUCN 적색목록 평가 자료 확보를 위해 IUCN Red List Criteria B의 분포범위(Extent of occurrence)와 점유면적(Area of occupancy)을 측정하였다. 물들메나무 분포도 작성을 위해 분포가 언급된 관련 문헌자료, 국립수목원 표본관(KH) 소장 표본정보, 국가생물종지식정보시스템(Nature) 종발생정보 DB, 그리고 현장조사 자료를 활용하였다. 이를 통해 한반도 특산식물 물들메나무는 지리산을 중심으로 전라남 북도, 경상남 북도 및 충청북도에 분포하고 있는 것으로 나타났으며, 북방한계지역은 경상북도 보현산으로 추정된다. 수집된 분포정보를 바탕으로 IUCN Red List Criteria B의 분포범위(Extent of occurrence)과 점유면적(Area of occupancy)을 계산한 결과 각각 $25,183km^2$, $96km^2$로 나타났다. 하지만 정확한 보전지위 평가를 위해서는 점유면적, 분포범위, 서식지 면적, 개체군 크기에 대한 지속적인 하락과 극단적인 변동을 측정할 수 있는 모니터링과 객관적인 자료가 요구된다.

• The Journal of the Petrological Society of Korea
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• v.5 no.2
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• pp.168-187
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• 1996

In the study area Uanggunbong-Samgunri area), Precambrian metamorphic complex, (Taebacksan gneiss complex, Hyundong gneiss complex, and Taebacksan schist complex) had undergone three different regional metamorphisms at least before Paleozoic. The Paleozoic sediments in the study area also had undergone three different metamorphisms at least. The first is low pressure type regional metamorphism, the second is low pressure type contact metamorphism due to the intrusion of Chunyang granite, and the last is medium pressure type metamorphism caused by thrust in south of Janggunbong area. The first metamorphism formed the prevailing metamorphic zones in the Paleozoic metasediments and the metamorphic grade of the first regional metamorphism increases from the chloritoid zone, through the staurolite zone, garnet zone, staurolite+biotite zone, and to the andalusite+biotite zone. The second metamorphism affected both Pre-Cambrian and Paleozoic metasediments located close to the Chunyang granite. The effect of the contact metamorphism is restricted to the very narrow zone around the granite. The third metamorphism that produced kyanite, is restricted to the very narrow region near the thrust fault in the south of Janggunbong with an E-W trend.

• Toxicological Research
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• v.12 no.2
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• pp.213-221
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• 1996

In order to develop a suitable secondary renal disease model and diagnostic markers of renal disease in the rat, the change of PIIIP (aminoterminal procollagen III peptide) in serum and hydroxyproline levels in the renal tissue that reflect the synthesis of extracellular matrix (ECM) during development of experimental renal diseases were observed. Two types of experimental primary diseases, diabetes mellitus administrated by streptozotocin (STZ, 75 mg/kg, i.p.) and liver cirrhosis produced by bile duct ligation/scission (BDL/s) operation, were induced. The hydroxyproline level increased according to the high PIIIP and NCl(carboxyterminal procollagen IV peptide) in Western blot analysis as early as 1 week in the STZ treated-rat kidney. Increased renal ECM was observed at 15 weeks in STZ and BDL/s model under the microscopic examination. High PAS positive reaction was found in capillary basement membrane in STZ treated-rats and mesangium in BDL/s operated rats at this time, showing the histological characteristics of diabetic nephropathy and cirrhotic glomerulonephritis in human, respectively. Such secondary renal failure were supported by additional tests including urinalysis and renal function test. The serum PIIIP detected by ELISA was a useful parameter to estimate synthesis rate of renal ECM during development of renal disease without extrarenal fibrosis i.e. liver cirrhosis in rats. This study is proposed that STZ treatment or BDL/s operation may be a suitable experimental animal model for the induction and development of chronic secondary renal diseases. Morover, it was found that hydroxyproline level in renal tissues was a good parameter of the change of renal ECM at the early stage of the diseases without apparent histological changes. Especially, serum PIIIP could be a choice as a diagnostic or prognostic marker during the development of renal diseases in rats.