• Title/Summary/Keyword: 나스트란

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Sleep Paralysis in Schizophrenia and Mood Disorder (정신분열병과 기분장애에서의 수면마비)

  • Park, Jae-Hong;Yang, Chang-Kook
    • Sleep Medicine and Psychophysiology
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    • v.9 no.2
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    • pp.115-121
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    • 2002
  • Objectives: Although sleep paralysis (SP) has been known as one of the symptoms of narcolepsy, recently it has become recognized as occurring frequently in the general population. However, the prevalence of SP and its associated factors in patients with major psychiatric disorders remain unknown. This study investigated the prevalence of SP and a variety of associated experiences in those patients. Methods: The subjects were 160 psychiatric patients and 143 age- and sex-matched controls. The Korean version SP questionnaire as well as the Sleep-Wake Schedule, Epworth Sleepiness Scale and Insomnia Severity Index were administered to all the subjects. The patients were referred from Dong-A University Hospital and consisted of 74 diagnosed as schizophrenia (47.7%), 26 as bipolar disorder (16.8%) and 55 as major depression (35.5%). Results: Nearly 42% of the patient group and 39% of the control group had experienced at least one episode of SP in their lifetime, with no significant difference between the groups. However, the patient group had experienced SP more frequently than the control group. Among all subjects, no gender difference in SP incidence was found. The peak age of onset was in the range of 16-25 years for both groups. Over eight tenths of both groups reported hallucinations and over seven tenths of both groups experienced fear accompanying SP. Conclusion: This study shows that there is no difference in the lifetime prevalence of SP between psychiatric patients and the general population, whereas frequency of SP experience is higher in psychiatric patients. Terrifying hallucinations and fearful feelings frequently accompany SP in both groups.

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New transfer standard for low vacuum region

  • 우삼용;한승웅;김부식;이상균
    • Proceedings of the Korean Vacuum Society Conference
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    • 1999.07a
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    • pp.44-44
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    • 1999
  • 저진공(1 kPa~ 100 kPa)은 대기압 측정, 비행고도, 기체의 온도 측정, 질량의 부력 보정, 레이저의 굴절률 측정등에 사용되는 영역으로 과학적 중요성을 갖고 있다. 또한 대기압 이상의 압력 측정과 고진공 측정의 경계적 역할도 수행하고 있어 압력 표준기의 국제 비교에 필수적으로 권장되는 역역이다. 이 영역에 주로 사용되는 압력 표준기는 수은 압력계(Mercury manometer)와 분동식 압력계(Deadweight piston gauge or Pressure)가 있다. 이들은 이동이 불편하거나 불가능하므로 표준기의 국제 비교에 사용되는 전달 표준기로는 보다 이동이 간편한 탄성 압력계인 CDG(Capacitance diaphragm Gauge)가 있다. 이 게이지는 반도체 산업의 공정 제어용으로도 많이 사용되고 있다. 그러나 게이지와 함께 사용되는 컨트롤러의 부피가 크고 무거우며 영점 이동이 커서 측정때 마다 재조정하여야 하는 단점이 있다. 본 논문에서는 이 같은 단점을 극복하기 위해 수정빔 진동형 진공 센서를 잔달 표준기로 사용하는 것에 대한 연구를 수행하였다. 수정빔 진동형 압력 센서는 수정빔으 공진주파수가 스트레인에 비례하는 것을 이용하여 제작된 센서로 주로 대기압 이상의 고압 측정에 많이 사용되고 있다. 먼저 수정빔의 압력과 주파수간의 관계를 측정하고 또한 내장된 수정 온도센서의 공진 주파수를 측정하여 온도 보상을 위한 자료로 사용하였다. 규격에 나와 있는 수정빔의 기하학적 형상으로부터 거동에 관한 이론 모델식을 구하고 압력교정 자료로부터 얻어진 데이터를 이 식과 비교 분석하여 적합한 특성식과 인자를 구하였으며 게이지의 불확도를 추정하였다.모델은 길이가 유한한 0-차원 실린더 모델로 가정하였고, 이에 대한 기하학적 성질 및 열역학적 성질은 유효계수를 고려하여 산출하였다. 진공용기 이중 벽 내부로 흐르는 질소가스의 유량과 온도의 계산은 진공용기 내벽과 외벽을 각각 독립적인 열전달 요소로 가정하여 구성한 모델을 이용하였다. 전체 해석에서 각 열전달 요소의 비열 값은 온도에 따라 변화하는 비열의 특성을 반영하였으며. 진공용기와 플라즈마 대향 부품의 방사율(emissivity)은 앞서 가정했던 각 온도 상승 곡선에 대해서 각각 0.1, 0.2, 1.3의 경우를 가정하여 계산하였다. 직선적으로 증가하는 온도 상승 곡선중 2$0^{\circ}C$/hr의 온도상승율을 갖는 경우가 다른 베이킹 시나리오 모델에 비해 효과적이라 생각되며 초대 필요 공급열량은 200kW 정도로 산출되었다. 실질적인 수치를 얻기 위해 보다 고차원 모델로의 해석이 필요하리라 생각된다. 끝으로 장기적인 관점에서 KSTAR 장치의 베이킹 계획도 살펴본다.습파라미터와 더불어, 본 연구에서 새롭게 제시된 주기분할층의 파라미터들이 모형의 학습성과를 높이기 위해 함께 고려된다. 한편, 이러한 학습과정에서 추가적으로 고려해야 할 파라미터 갯수가 증가함에 따라서, 본 모델의 학습성과가 local minimum에 빠지는 문제점이 발생될 수 있다. 즉, 웨이블릿분석과 인공신경망모형을 모두 전역적으로 최적화시켜야 하는 문제가 발생한다. 본 연구에서는 이 문제를 해결하기 위해서, 최근 local minimum의 가능성을 최소화하여 전역적인 학습성과를 높여 주는 인공지능기법으로서 유전자알고리즘기법을 본 연구이 통합모델에 반영하였다. 이에 대한 실

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Isolation and characterization of a monodehydroascorbate reductase gene in poplar (Populus alba × P. glandulosa) (현사시나무 monodehydroascorbate reductase (MDHAR) 유전자의 분리 및 발현특성)

  • Yoon, Seo-Kyung;Park, Eung-Jun;Bae, Eun-Kyung;Choi, Young-Im;Kim, Joon-Hyeok;Lee, Hyoshin
    • Journal of Plant Biotechnology
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    • v.41 no.4
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    • pp.194-200
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    • 2014
  • Monodehydroascorbate reductase (MDHAR) is an important enzyme that plays a role in the detoxification of reactive oxygen species (ROS) by maintaining reduced pool of ascorbate through recycling the oxidized form of ascorbate. In this study, we isolated a PagMDHAR1 gene from Populus alba ${\times}$ P. glandulosa, and investigated its expression characteristics. The PagMDHAR1 cDNA encodes a putative 434 amino acids containing FAD- and NAD(P)H-binding domains. Southern blot analysis indicated that a single nuclear gene encodes this enzyme. Northern hybridization analysis revealed that PagMDHAR1 is highly expressed in both suspension cells and flower tissues, while its expression levels were enhanced by drought, salt, cold, wounding and ABA. Therefore, PagMDHAR1 might be expressed in response to abiotic stress through the ABA-mediated signaling pathway in this poplar species, suggesting that the PagMDHAR1 plays an important role in the defense mechanisms against oxidative stress.

Skin Care Effects of Green Tea (녹차의 피부보호효과)

  • Lee, Byeong-Gon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.4 s.54
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    • pp.311-321
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    • 2005
  • Tea (Camellia sinenis) is a popular beverage consumed worldwide. Since green tea, mainly consumed in Asia, has various biological activities, green tea components became one of the most favorite candidates as a functional materials for cosmetics and functional foods. The biological activities of green tea for skin cue have been ranged from protection of epidermal cells to the stimulation of extracellular matrix (ECM) biosynthesis. Green tea polyphenols (GTPs), which are active ingredients of green tea, possess anti-inflammatory, anti-carcinogenic and immune potentiation properties as well as antioxidant. They also modulate intracellular signal transduction pathways. GTPs decrease ultraviolet (UV)-induced oxidative stress, thus suppress mitogen-activated protein kinase (MAPK) pathway and apoptosis in keratinocytes. In addition, GTPs prevent the Induction of inflammatory mediators, such as cyclooxygenase-2 (COX-2), interleukin-8 (IL-8), and vascular endothelial growth factor (VEGF) by tumor necrosis factor alpha $(TNF{\alpha})$ or chemical treatment in keratinocytes. GTPs treatment protects from chemical-or UV-induced skin tumor incidence in animal experiment. Besides, GTPs stimulate keratinocyte differentiation and proliferation of normal and aged epidermal cells, resectively, and suppress matrix metalloproteinases (MMPs) release. According to the progress of formulation study, green tea components will be guaranteed materials for the more effective skin cue products.

Finite Element Analysis(fem) of The Fixed Position of the Velcro Band for the 3D Print Wrist Brace made using the Dicom File (CT Dicom 파일을 이용하여 제작한 3D Print 손목보호대용 Velcro band 고정위치의 유한요소해석(FEM))

  • Choi, Hyeun-Woo;Seo, An-Na;Lee, Jong-Min
    • Journal of the Korean Society of Radiology
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    • v.15 no.5
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    • pp.585-590
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    • 2021
  • Wrist braces are being used for patients with wrist trauma. Recently, many studies have been conducted to manufacture custom wrist braces using 3D printing technology. Such 3D printing customized orthosis has the advantage of reflecting various factors such as reflecting different shapes for each individual and securing breathability. In this paper, the stress on the orthosis by the number and position of Velcro bands that should be considered when manufacturing a 3D printing custom wrist brace was analyzed. For customized orthosis, 3D modeling of the bone and skin regions was performed using an automatic design software (Reconeasy 3D, Seeann Solution) based on CT images. Based on the 3D skin area, a wrist orthosis design was applied to suit each treatment purpose. And, for the elasticity of the brace, a wrist brace was manufactured with an FDM-type 3D printer using TPU material. To evaluate the effectiveness according to the number and position of the Velcro band of the custom 3D printed wrist brace, the stress distribution of the brace was analyzed by the finite element method (FEM). Through the finite element analysis of the wrist orthosis performed in this study, the stress distribution of the orthosis was confirmed, and the number and position of the orthosis production and Velcro bands could be confirmed. These experimental results will help provide quality treatment to patients.

OmpR Is Essential for Growth and Expression of Virulence-related Genes in the Fish Pathogen Edwardsiella piscicida (어류 병원체 Edwardsiella piscicida의 OmpR은 생육과 병원성과 관련된 유전자의 발현에 필수적)

  • Ray, Durga;Kim, Yeon Ha;Choe, unjeong;Kang, Ho Young
    • Journal of Life Science
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    • v.31 no.1
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    • pp.28-36
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    • 2021
  • Edwardsiella piscicida is a significant cause of hemorrhagic septicemia in fish and gastrointestinal infections in humans. Survival bacteria require specialized mechanisms to adapt to environmental fluctuations. Hence, to understand the mechanism through which E. piscicida senses and responds to environmental osmolarity changes, we determined the protein expression profile and physiological properties under various salinity conditions in this study. The OmpR protein is a part of the Env-ZOmpR two-component system that has been implicated in sensing salt stress in bacteria. However, the physiological role played by this protein in E. piscicida remains to be elucidated. Therefore, in this work, the function of the OmpR protein in response to salt stress was investigated. Phenotypic analysis revealed that, in the mutant, three of the biochemical phenotypes were different from the wild type, including, citrate utilization, hydrogen sulfide, and indole production. Introduction of the plasmid containing the entire ompR gene to the mutant strain returned it to its parental phenotype. The retarded growth rate also partially recovered. Furthermore, in our studies, OmpR was not found to be related to cell motility. Taken together, our results from the mutational analysis, the growth assay, MALDI-TOF MS, qRT-PCR, and the phenotype studies suggest that the OmpR of E. piscicida is implicated in osmoregulation, growth, expression of porins (ETAE_1826), virulence-related genes (EseC, EseD and EvpC), and certain genes of unknown function (ETAE_1540 and ETAE_2706).

Academic Stress and Its Influencing Factors among Medical and Non-Medical Students (의대생과 비의대생의 학업 스트레스와 영향요인에 관한 연구)

  • Seong, Anna;Heo, Suyeon;Yoon, Jeonggyo;Lee, Ji Yeon;Choi, Min Gi;Jeon, Jong ha;Kim, Jae Hoon;Park, Kwi Hwa;Im, Jeong-Soo;Ko, Kwang-Pil;Jung, Jaehun;Choi, Yoon-Hyeong
    • Korean Medical Education Review
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    • v.23 no.2
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    • pp.128-138
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    • 2021
  • This study examined the relationships among personality traits, coping efficacy, and academic stress in medical and non-medical students in South Korea, and investigated the mediating effect of coping efficacy in the relationship between personality traits and academic stress. The study group comprised 210 medical students and 175 non-medical students. They were asked to rate their personality traits, coping efficacy, and academic stress. The data were analyzed using IBM SPSS ver. 26.0 (IBM Corp., Armonk, NY, USA) and AMOS ver. 26.0 (IBM Corp.). Medical students scored higher for examination stress and lower for extroversion than non-medical students. In both groups, extroversion and conscientiousness positively affected coping efficacy, while neuroticism influenced it negatively. Neuroticism directly influenced all types of academic stress in both groups, while extroversion and conscientiousness only had direct effects on examination stress among medical students. Coping efficacy mediated the associations between personality traits and academic stress, except for the relationship between neuroticism and grade stress among medical students. The study indicates that coping efficacy had a significant effect on relieving academic stress among students with higher scores for extroversion and conscientiousness. Efforts should be made to decrease neuroticism to lower academic stress, as the relationship between neuroticism and academic stress is not directly influenced by coping efficacy. The implications of these results are discussed regarding a consultation system for students, especially those in medical school.

Reconstruction Of Photo-Realistic 3D Assets For Actual Objects Combining Photogrammetry And Computer Graphics (사진측량과 컴퓨터 그래픽의 결합을 통한 실제 물체의 사실적인 3D 에셋 재건)

  • Yan, Yong
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.147-161
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    • 2021
  • Through photogrammetry techniques, what current researches can achieve at present is rough 3D mesh and color map of objects, rather than usable photo-realistic 3D assets. This research aims to propose a new method to create photo-realistic 3D assets that can be used in the field of visualization applications. The new method combines photogrammetry with computer graphics modeling. Through the description of the production process of three objects in the real world - "Bullet Box", "Gun" and "Metal Beverage Bottle," it introduces in details the concept, functions, operating skills and software packages used in the steps including the photograph object, white balance, reconstruction, cleanup reconstruction, retopology, UV unwrapping, projection, texture baking, De-Lighting and Create Material Maps. In order to increase the flexibility of the method, alternatives to the software packages are also recommended for each step. In this research, 3D assets are produced that are accurate in shape, correct in color, easy to render and can be physically interacted with dynamic lighting in texture. The new method can obtain more realistic visual effects at a faster speed. It does not require large-scale teams, expensive equipment and software packages, therefore it is suitable for small studios and independent artists and educational institutions.

A Study on the Linoleum of the Deoksugung and Changdeokgung Palaces in the Early 20th Century: focusing on its manufacturing process, characteristics, and usage (20세기 초 덕수궁·창덕궁에 유입된 리놀륨(Linoleum) 바닥재 연구: 리놀륨의 제작 방식과 특성 및 사용을 중심으로)

  • Choi, Jihye
    • Korean Journal of Heritage: History & Science
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    • v.54 no.1
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    • pp.18-31
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    • 2021
  • Linoleum is a resilient, hygienic, and eco-friendly floor covering. It was developed in England by Frederick Walton in 1863. Made of cork flour, linseed oil, and burlap as its main materials, the flexible and waterproof linoleum became globally popular in the early 20th century. Unlike the vinyl coverings, the burlap-backed linoleum was used not only in commercial spaces but also in household areas like kitchens, bathrooms, and even living rooms. As a global product, linoleum was imported and used in Korean palaces like Deoksugung and Changdeokgung in the early modern period. According to the record Deoksugung Won-Ahn, linoleum was applied to the major buildings, including Hamnyeongjeon, Deokhongjeon, and Jeonggwanheon, and various other venues. The linoleum used in these places are mainly monochrome blue and brown color, which probably means that they are from England. The trade records in the early 20th century show that linoleum was imported mainly from England and America. The Ewangjik building floor plan in the Changdeokgung Palace shows that linoleum was used extensively. There are even some originals, which were laid in 1920 and left in the Changdeokgung Palace. When Daejojeon and Huijeongdang were rebuilt in 1920, the interior was outfitted with western features and linoleum was used in areas such as bathrooms, the tonsorial parlor, and one of the rooms on the west side of Huijeongdang. In situ in the Daejojeon and Huijeongdang areas in the Changdeokgung Palace are monochrome, patterned black, and stylized floral tile patterned, which are closely similar to American products made by ALC and Armstrong company. This study will help us better understand linoleum's characteristics, its uses and the material itself. It will also form the basis for the restoration of Changdeokgung Palace as well as other modern interiors with linoleum flooring in the future.

Emission Rates of Biogenic Volatile Organic Compounds from Various Tree Species in Korea (II): Major Species in Urban Forests (국내 수종별 BVOCs 방출량(II): 도시 숲 주요 수종)

  • Hanna, Chang;Jounga, Son;Juwan, Kim;Junhyuk, Kim;Yeongseong, Kim;Won-Sil, Choi;Young-Kyu, Lee
    • Journal of Korean Society of Forest Science
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    • v.111 no.4
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    • pp.490-501
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    • 2022
  • In this study, the isoprene and terpene emissions from 32 major urban tree species were investigated. We conducted sampling using a dynamic enclosure system between June and July 2021. Seedlings aged < three years were enclosed in a chamber consisting of a 400 L transparent Tedlar bag. The air flow from the outlet of the chamber was sampled using Tenax-filled sorbent tubes under standard conditions (temperature: 30°C; PAR: 1,000 μmol/m2/sec). A thermal desorption gas chromatography/mass spectrometry system was used to analyze the following 38 biogenic volatile organic compounds: isoprene, monoterpenes, sesquiterpenes, oxygenated monoterpenes, and oxygenated sesquiterpenes. Isoprene emitters included Quercus mongolica, Salix koreensis, Robinia pseudoacacia, and Salix chaenomeloides. Monoterpene emitters included Pinus strobus, Cedrela sinensis, and Cercis chinensis. The monoterpene emission profiles were dominated by á-pinene, myrcene, camphene, and limonene. The predominant oxygenated monoterpene and oxygenated sesquiterpene were eucalyptol and caryophyllene oxide, respectively. For all species, the contributions of sesquiterpenes and oxygenated sesquiterpenes were relatively low.