• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.28 no.2
• /
• pp.100-105
• /
• 2017

Background and Objectives : Adductor type spasmodic dysphonia (ADSD) is neurogenic disorder and focal laryngeal dystonia, while muscle tension dysphonia (MTD) is caused by functional voice disorder. Both ADSD and MTD may be associated with excessive supraglottic contraction and compensation, resulting in a strained voice quality with spastic voice breaks. The aim of this study was to determine the utility of spectrogram analysis in the differentiation of ADSD from MTD. Materials and Methods : From 2015 through 2017, 17 patients of ADSD and 20 of MTD, underwent acoustic recording and phonatory function studies, were enrolled. Jitter (frequency perturbation), Shimmer (amplitude perturbation) were obtained using MDVP (Multi-dimensional Voice Program) and GRBAS scale was used for perceptual evaluation. The two speech therapist evaluated a wide band (11,250 Hz) spectrogram by blind test using 4 scales (0-3 point) for four spectral findings, abrupt voice breaks, irregular wide spaced vertical striations, well defined formants and high frequency spectral noise. Results : Jitter, Shimmer and GRBAS were not found different between two groups with no significant correlation (p>0.05). Abrupt voice breaks and irregular wide spaced vertical striations of ADSD were significantly higher than those of MTD with strong correlation (p<0.01). High frequency spectral noise of MTD were higher than those of ADSD with strong correlation (p<0.01). Well defined formants were not found different between two groups. Conclusion : The wide band spectrograms provided visual perceptual information can differentiate ADSD from MTD. Spectrogram analysis is a useful diagnostic tool for differentiating ADSD from MTD where perceptual analysis and clinical evaluation alone are insufficient.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.32 no.4
• /
• pp.230-241
• /
• 2020

Since the construction of Pohang New Port, the problems of the low harbor tranquility caused by decreasing port operation rate has been continuously reported. In order to improve the harbor tranquility, a detached breakwater (DB) has been constructed outside the outer breakwater of Pohang New Port in 2018~2020. In this study, the effectiveness of the DB was proved by comparing the reduction rates of wave heights that were observed before and after the construction of the DB. First, the observed data were compared with the numerical model results available from a previous study, and the model data showed reasonable agreement with measured data at 3 out of 4 locations inside the port. The discrepancy in one of the locations was because the model could not accurately calculated the effect of wave interference in the inner corner of the port. The observation data showed excellent results that the number of waves that exceeded 0.3 m, the critical value to reach desired harbor tranquility, was significantly reduced after the construction of the DB. In addition, the reduction rate, the ratio of wave heights between outside and inside of the port, was decreased after the DB construction, which proved that properly designed coastal structures such as DB in this study could be effective in improving the port tranquility. The results of this study can be usefully applied for solving problems in similar cases.

• Journal of Sensor Science and Technology
• /
• v.11 no.3
• /
• pp.155-162
• /
• 2002

The sensing properties of carbon monooxide were investigated as a function of mixing ratio and the lamination structure of 3mol% ZnO-doped $SnO_2$ and 3mol% $SnO_2$-doped ZnO. The lamination structures were fabricared monolayer, double layer, and hetero layer of $SnO_2$, Zno, and theirs mixture composition using thick film process. There was no second phase by the reaction of $SnO_2$ and ZnO. The conductance was decreased by the addition of ZnO in $SnO_2$, but it was increased with the addition of $SnO_2$ in ZnO. The conductance was increased with temperature and the inlet of CO. There was no improvement of sensitivity in the structure of mono- and double-layer. The hetero-layer structure, however, of $SnO_2$ 3ZnO-ZnO $3SnO_2$ showed the higher resistivity and the highest sensitivity. Ohmic characteristics was confirmed by the linear properties for I-V measurements.

• Journal of Sensor Science and Technology
• /
• v.4 no.3
• /
• pp.71-79
• /
• 1995

For the fabrication of high sensitive intrinsic fiber optic Fabry-Perot interferometeric sensor, the deposition conditions of $TiO_{2}$ thin film used to the internal mirrors of the sensor were investigated. The $TiO_{2}$ film deposited by RF magnetron sputter had higher refractive index ($2.36{\sim}2.48$) and better stoiciometry (O/Ti = 2) than that deposited bye-beam evaporator. In the case of forming $TiO_{2}$ internal mirror by using fusion splicing technique, the $TiO_{2}$ reflection mirror deposited by RF magnetron sputter in the condition of 120W RF power showed high. reflectance and excellent controllability of reflection power. The fabricated intrinsic fiber optic Fabry-Perot interferometer with two $TiO_{2}$ internal mirrors deposited under the condition showed very stable fringe patterns. It is, therefore, expected that the interferometer will be applicable to various high precision sensors.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.26 no.2
• /
• pp.117-121
• /
• 2015

Background : Cepstral analysis which is obtained from Fourier transformation of spectrum has been known to be effective indicator to analyze the voice disorder. To evaluate the voice disorder, phonation of sustained vowel /a/ sound or continuous speech have been used but the former was limited to capture hoarseness properly. This study is aimed to compare the effectiveness in analysis of cepstrum between the sustained vowel /a/ sound and continuous speech. Methods : From March 2012 to December 2014, total 72 patients was enrolled in this study, including 24 unilateral vocal cord palsy, vocal nodule and vocal polyp patients, respectively. The entire patient evaluated their voice quality by VHI (Voice Handicap Index) before and after treatment. Phonation of sustained vowel /a/ sample and continuous speech using the first sentence of autumn paragraph was subjected by cepstral analysis and compare the pre-treatment group and post-treatment group. Results : The measured values of pre and post treatment in CPP-a (cepstral peak prominence in /a/ vowel sound) was 13.80, 13.91 in vocal cord palsy, 16.62, 17.99 in vocal cord nodule, 14.19, 18.50 in vocal cord polyp respectively. Values of CPP-s (cepstral peak prominence in text-based speech) in pre and post treatment was 11.11, 12.09 in vocal cord palsy, 12.11, 14.09 in vocal cord nodule, 12.63, 14.17 in vocal cord polyp. All 72 patients showed subjective improvement in VHI after treatment. CPP-a showed statistical improvement only in vocal polyp group, but CPP-s showed statistical improvement in all three groups (p<0.05). Conclusion : In analysis of cepstrum, text-based analysis is more representative in voice disorder than vowel sound speech. So when the acoustic analysis of voice by cepstrum, both phonation of sustained vowel /a/ sound and text based speech should be performed to obtain more accurate result.

• Journal of Veterinary Clinics
• /
• v.20 no.3
• /
• pp.376-383
• /
• 2003

To establish the differential diagnosis and treatment method in bovine ovarian cysts, specially ovarian cysts with corpus luteum, serum progesterone concentration, rectal palpation and ultrasonography for measuring the cystic wall thickness and diameter of cyst and corpus luteum were investigated from 1,188 dairy cows with ovarian cysts. The plasma progesterone concentrations were 0.3$\pm$0.4 (mean$\pm$SD) ng/ml in 629 cows with follicular cysts, 3.7$\pm$1.1 ng/ml in 431 cows with luteal cysts, and 3.8$\pm$1.2 ng/ml in 128 cows with coexist of ovarian cysts and corpus luteum, respectively. The cystic wall thickness by ultrasonography were 1.6$\pm$0.4 mm in 629 cows with follicular cysts, 4.2$\pm$1.5 mm in 431 cows with luteal cysts, and 1.6$\pm$0.6 mm in 128 cows with coexist of ovarian cysts and corpus luteum, respectively. The days from initial treatment to insemination in follicular cysts were 28.1$\pm$6.9 days in treatment of GnRH alone, 15.9$\pm$2.9 days in combination of GnRH and dinoprost, and 15.1$\pm$3.1 days in combination of GnRH and cloprostenol. The percentages of cows conceived within 100 days after initial treatment were 61 %, 68% and 73% in treatment of GnRH alone, combination of GnRH and dinoprost, and combination of GnRH and cloprostenol, respectively. The days from initial treatment to insemination in luteal cysts were 3.8$\pm$0.6 days in treatment of dinoprost alone and 3.8$\pm$0.7 in cloprostenol alone. The percentages of cows conceived within 100 days after initial treatment were 69.5% and 68.5% in treatment of dinoprost and cloprostenol, respectively. The days from initial treatment to insemination in coexist of cysts and corpus luteum were 3.7$\pm$0.7 days in treatment of dinoprost alone and 3.8$\pm$0.6 in cloprostenol alone. The percentages of cows conceived within 100 days after initial treatment were 87% and 84% in treatment of dinoprost and cloprostenol, respectively. These results suggest that the best choice for treatment agents in ovarian cysts were combination of GnRH and PGF$_2$$\alpha$ in follicular cysts, and the PGF$_2$$\alpha$ in luteal cysts and in coexist of cysts and corpus luteum, respectively. In conclusion, it is suggest that ultrasonography is useful diagnostic tool for diagnosis and selection of treatment remedy in cystic ovaries of bovine.

• Journal of Veterinary Clinics
• /
• v.22 no.3
• /
• pp.253-258
• /
• 2005

The aim of this study was to estimate the time of ovulation and mating derived by plasma progesterone and estradiol-$17{\beta}$ concentrations. The 11 pregnant Shih-tzu bitches were investigated the plasma progesterone and estradiol-$17{\beta}$ concentrations from proestrus to parturition. Gestation length in the 11 pregnant bitches was $61.9{\pm}1.1\;(mean{\pm}SD)$ days when Day 0 was timed from the day that plasma progesterone concentration was first increased above 4.0 ng/ml. The litter size was $3.8{\pm}0.3$ pups. Plasma progesterone concentrations were increased at the first day of vulvar bleeding and showed at Day 0 with $5.2{\pm}0.3$ ng/ml. It was gradually increased to reach a peak at Day 15 with $42.6{\pm}3.7ng/ml$, thereafter it was gradually decreased to below Day 62. Plasma estradiol-$17{\beta}$ concentrations were increased above 1.0 pg/ml at the first day of vulvar bleeding and showed a peak at Day -2 with $33.5{\pm}8.0$ pg/ml, thereafter it was gradually decreased. When Day 0 was timed from the day that plasma progesterone concentration was first increased above 4.0 ng/ml, plasma estradiol-$17{\beta}$ concentration reached a peak at Day -2. In conclusion, these results indicated that ovulation was estimated to occur the day when plasma progesterone concentration was first increased above 4.0 ng/ml after the first day of bleeding. It was estimated that mating time was the day when plasma progesterone concentration was between $3.0{\~}8.0$ ng/ml.

• Journal of Veterinary Clinics
• /
• v.22 no.3
• /
• pp.233-238
• /
• 2005

This study was undertaken to determine the normal serial ultrasonographic appearance of the postpartum uterine involution. Postpartum changes in uterine shape, architecture, echogenicity and diameter were monitored by ultrasonography in 10 Shih-tzu bitches. Serial ultrasonographic examination was done daily during the first week, 3 days interval from 8 to 30 days, and weekly from 31 to 100 days postpartum. All 10 postpartum bitches had normal involution by gross finding, vaginal discharges, and by ultrasonographic findings, uterine shape and echogenicity. The uterine diameter in the placental sites was decreased from $23.56{\pm}1.45$ mm at 1 day to $14.08{\pm}1.55$ mm at 7 day, and in the interplacental sites was decreased from $14.64{\pm}1.28$mm at 1day to $9.61{\pm}1.46$mm at 7 day postpartum. At 65 days postpartum the uterine diameter was 5-6 mm both placental and interplacental sites, and the uterine horns were uniform hypoechic, tubular structures without enlargement. Therefore, complete involution of the uterus occured 65 days. It was concluded that normal postpartum uterine involution in Shih-tzu bitches appeared to be completed 65 days postpartum by gross findings such as vaginal discharges, and ultrasonographic findings. And ultrasonographic characteristics of the postpartum uterine involution were described. Therefore, these result suggest that ultrasonographic assessment is a reliable method for diagnosing the subinvolution of placental sites and uterine dysfunction, such as pyometra in the bitch.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2018.04a
• /
• pp.77-77
• /
• 2018

미역의 뿌리부분인 미역귀에는 알긴산과 후코이단 성분이 풍부하고 고혈압과 당뇨등과 같은 성인병을 예방하는데 도움이 된다. 후코이단은 미역과 다시마 같은 갈조류에서 추출된 천연물질로 특히 면역력을 활성화하고 항암작용으로 잘 알려져 있다. 알긴산 등 유용성분이 함유된 것으로 알려진 미역귀의 유용성분을 분석하여, 향후 미역귀를 활용한 제품개발의 기초자료를 제공하고자 본 연구를 수행하였다. 본 연구에 사용된 미역귀는 2015년 12월 완도 금일수산에서 제공받아 연구재료로 활용하였다. AOAC방법에 따라 분석한 미역귀의 일반성분은 수분이 대부분을 차지하였으며, 조섬유와 가용성 무질소물 함량이 높게 나타났다. 이는 시료로 사용한 미역귀가 수확 후 바로 냉동보관 되어서 수분함량이 높은 것으로 보여진다. 유리당은 미역귀 1g에 증류수를 가하여 $60^{\circ}C$에서 4시간 추출 한 후, 원심분리(3,000 rpm, 30 min)하여 $0.45{\mu}m$ membrane filter (Millipore Co., USA)로 여과한 여액을 HPLC (High Performance Liquid Chromatography)를 이용하여 분석한 결과, 미역귀의 유리당은 Galactose 1종만이 검출되었다. 미역귀의 구성아미노산과 유리아미노산은 $0.45{\mu}m$ membrane filter로 여과하여 얻은 여액을 일정량 취하여 AccQ-Tag 시약을 사용하여 유도체화 시킨 후 HPLC로 분석하였다. 미역귀의 구성아미노산은 glutamic acid, aspartic acid, alanine, lysine, threonine, valine, arginine 순으로 높은 함량을 나타내었으며, 유리아미노산은 glutamic acid, alanine, threonine, arginine, lysine 순으로 높은 함량을 나타내었다. 미역귀의 유리아미노산함량은 표고에 비하여 현저히 낮은 함량이 나타났으며, 주요아미노산은 해조류의 풍미를 대표하는 아미노산인 glutamic acid와 alanine으로 나타났다.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2018.04a
• /
• pp.78-78
• /
• 2018

미역은 갈조식물인 미역과에 속하는 1년생 바닷말로서 주로 어린 줄기와 잎부분을 식용으로 한다. 폐기부로 분류되는 미역귀 부분 또한 가식부 이상으로 풍부한 미네랄과 알긴산을 함유하고 있으며 이를 이용한 건강 친화적인 슬라이스 잼의 개발을 목적으로 연구를 수행하였다. 제품 개발의 소재화를 위한 연구의 일환으로 미역귀 알긴산 추출, 알긴산의 항산화활성(DPPH, ABTS, SOD 유사활성, total polyphenol, 세포 독성, NO생성 억제능을 수행한 바는 아래와 같다. 미역귀 알긴산 추출물을 각각 10, 50, 100, $500{\mu}g/mL$의 농도로 처리한 시험구들의 전자공여능을 확인한 결과 각각 2.8, 27.5, 35.9, 43.4%로 나타났으며, ABTS 라디칼 소거능은 각각 4.2, 21.6, 33.4, 67.4%로 나타났다. 동일한 농도로 처리하였을 때 SOD 유사활성은 각각 9.2, 12.4, 23.2, 30.8%로 나타났다. 미역귀 알긴산 추출물의 total polyphenol은 $19.16{\pm}0.08mg%$로 확인되었다. 세포생존율은 10, 50, 100, $500{\mu}g/mL$의 농도로 처리하였을 때 118.8%, 120.7%, 121.1%, 124.9%로 나타났다. NO생성 억제능을 동일한 농도에서 확인한 결과 각각 3.1, 5.1, 7.9, 9.6%로 확인되었다. 본 연구결과 미역귀 알긴산 추출물은 항산화능이 탁월하게 나타나 건강 친화적인 기능성 소재로 활용도가 높을 것으로 기대된다.