• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.101-112
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• 1997

The purpose of this study was to examine usefulness of KEDI-Individual Basic Learning Skills Test as a diagnostic tool of learning disorders(LD). Learning disorder group consisted of two subgroups, verbal learning disorder group(VLD, n＝34) and nonverbal learning disorder group(NVLD, n＝14). Comparison group consisted of Dysthymia Disorder subgroup(n＝11) and Normal subgroup(n＝20). Performance of intelligence test and achievement test was examined in all 4 subgroups. In KEDI-WISC, VLD subgroup revealed primary problems in vocabulary, information and verbal-auditory attention test. NVLD group revealed primary problems in almost all performance tests such as visual acuity, psycho-motor coordination speed and visual-spatial organizations ability subtest. In KEDI-Individual Basic Learning Test, VLD group revealed primary problems in phonological coding process, word recognition and mathematics. For successful classification of LD children, the importance of achievement test and intelligence test was discussed by discriminant analysis and factor analysis. The results indicate that KEDI-Individual Basic Learning Skills is of considerable usefulness in diagnosing LD, but must be used in subtests, and additional tests must be conducted for thorough exploration of LD.

• Journal of dental hygiene science
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• v.14 no.2
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• pp.191-197
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• 2014

The purpose of this study was to evaluate the tooth whitening efficacy of 2.9% hydrogen peroxide strip with primer gel of alkaline condition and containing metallic salts as catalyst in-vitro. Hydroxyapatite (HAP) disk was made by compressing and sintering 0.3 g of mixture of HAP powder and polyvinyl alcohol. This HAP disk was stained using modified Stookey's methods. Main bleaching materials were 2.9% hydrogen peroxide strips and the primer gel containing metallic salts as catalyst and pH controller. Stained HAP disks were allocated to each control or experimental groups by color grade. Stained HAP disks were treated for 30 minutes in $37^{\circ}C/80%$ incubator for wetting, then each primer gel according to control or each test group was spread and strips were attached. After 30 minutes for each group strips were detached and HAP disks were washed, dried then color was measured by colorimeter. Efficacy was evaluated by comparing ${\Delta}L$ values of HAP disks at baseline and after treated. Among some kinds of metallic salts for as catalyst, ferric chloride showed best improvement of efficacy and it was statistically significant (p<0.05) compared to control group. Evaluating whitening efficacy according to various pH of primer, efficacy using primer of alkaline condition was increased significantly (p<0.05) compared to control and primers of acidic or neutral conditions. Evaluating whitening efficacy for time course, efficacy of test group for 30 minutes was similar to that of control for 120 minutes. It can be concluded that 2.9% hydrogen peroxide strips using with primer of alkaline condition and containing ferric chloride showed significantly increased whitening efficacy compared to the case of strips only.

• Journal of Dental Rehabilitation and Applied Science
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• v.19 no.1
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• pp.17-25
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• 2003

Treatment with implants of single tooth missing cases is both functional and esthetic. Although the success rate of single-tooth implant treatments is increasing, sometimes it makes some problems. Problems with single-tooth implant treatments include soft tissue complications, abutment screw fracture, and most commonly, abutment screw loosening, and these involve the instability of the dental implant-superstructure interface. This study investigated and compared dental implant screw joint micromotion of various implant system with external connection or internal connection when tested under simulated clinical loading, Six groups (N=5) were assessed: (1) Branemark AurAdapt (Nobel Biocare, Goteborg, Sweden), (2) Branemark EsthetiCone (Nobel Biocare, Goteborg, Sweden), (3) Neoplant Conical (Neobiotec, Korea), (4) Neoplant UCLA (Neobiotec, Korea), (5) Neoplant 5.5mm Solid (Neobiotec, Korea), and (6) ITI SynOcta (Institute Straumann, Waldenburg, Switzerland). Six identical frameworks were fabricated. Abutment screws were tightened to 32-35 Ncm and occlusal screw were tightened to 15-20 Ncm with an electronic torque controller. A mechanical testing machine applied a compressive cyclic load of 20kg at 10Hz to a contact point on each implant crown. Strain gauge recorded the micromotion of the screw joint interface once a second. Data were selected at 1, 500, 5,000, 10,000, 20,000, 30,000, 40,000 and 50,000 cycle and 2-way ANOVA test was performed to assess the statistical significance. The results of this study were as follows; The micromotion of the implant-superstructure in the interface increased gradually through 50,000 cycles for all implant systems. In the case of the micromotion according to cycle increase, Neoplant Conical and Neoplant UCLA system exhibited significantly increasing micromotion at the implant-superstructure interface (p<0.05), but others not significant. In the case of the micromotion of the implant-superstructure interface at 50,000 cycle, the largest micromotion were recorded in the Branemark EsthetiCone, sequently followed by Neoplant Conical, Neoplant UCLA, Branemark AurAdapt, ITI SynOcta and Neplant Solid. Internal connection system showed smaller micromotion than external connection system. Specially, Neoplant Solid with internal connection system exhibited significantly smaller micromotion than other implant systems except ITI SynOcta with same internal connection system (p<0.05). In the case of external connection, Branemark EsthetiCone and Neoplant Conical system with abutment showed significantly larger micromotion than Branemark AurAdapt without abutment (p<0.05).

• Tuberculosis and Respiratory Diseases
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• v.70 no.5
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• pp.405-415
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• 2011

Background: In an effort to find alternative therapeutic agents to prevent excessive fibrosis as a sequela to complicated parapneumonic effusion or empyema, we examined the effect of tissue plasminogen activator (tPA) as a fibrinolytic agent combined with talc or transforming growth factor (TGF)-${\beta}1$ in a human pleural mesothelial cell line, MeT-5A. Methods: MeT-5A cells were stimulated with various doses of talc, doxycycline or TGF-${\beta}1$ for 24 h and then were treated with tPA for an additional 24 h. Cell viability was measured by MTT assay. The production of interleukin (IL)-8 and vascular endothelial growth factor (VEGF) in the culture supernatants was measured by ELISA. Real-time PCR was carried out for measurement of type I collagen mRNA. Results: MeT-5A cells treated with talc showed a dose-dependent increase in production of IL-8. Talc also increased production of type I collagen mRNA at low doses, but talc did not influence the induction of VEGF. Addition of tPA to talc-stimulated cells showed further increases in the production of IL-8, but tPA did not influence the production of VEGF or type I collagen mRNA. TGF-${\beta}1$ increased the production of both VEGF and collagen type I mRNA, both of which were effectively inhibited by additional tPA treatment in MeT-5A cells. Conclusion: TGF-${\beta}1$ is a potent inducer of collagen synthesis without induction of IL-8 in MeT-5A cells. Addition of tPA after TGF-${\beta}1$ stimulation inhibited further fibrosis by direct inhibition of collagen mRNA synthesis as well as by inhibition of VEGF production.

• Journal of Acupuncture Research
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• v.28 no.5
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• pp.103-110
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• 2011

Objectives : The purpose of this study is to investigate the effect and adverse events of Gamiwolbigachul-tang on the changes of body composition and musculoskeletal pain in overweight patients. Methods : A total of 28 patients with overweight patients who were complaining musculoskeletal pain were treated with Gamiwolbigachul-tang more than 4 weeks between January 2011 and August 2011 in Kyung Hee University Oriental Medical Hospital were observed. We have evaluated the efficacy of treatments by measuring the changes of body composition (Body weight, Body mass index, Skeletal muscle mass, Body fat mass and Waist hip ratio) and musculoskeletal pain. The 28 patients were analyzed according to the distribution of sex, age, body compostition and musculoskeletal pain. Results : 1. There were statistically significant changes on Body weight and BMI in 28 patients after 4 weeks of treatment. 2. Gamiwolbigachul-tang had effect on reducing Body fat mass rather than Fat free mass. 3. There were statistically significant changes on musculoskeletal pains such as lower back pain, knee pain after treatment. 4. There were few side effects except those common complications such as insomnia(3 patients), palpitation(2 patients) and indigestion(1 patients), which did not have effects on everyday living. Conclusions : These results suggest that Gamiwolbigachul-tang will be beneficial for overweight patients with musculoskeletal pain, having both effectiveness and safety.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.15 no.1
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• pp.75-81
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• 2004

Objectives：This study was designed to compare the emotional/behavioral characteristics between the siblings of children with autism and normally developing children. Methods：The subjects were 34 children between 10 and 16 years of age, 17 siblings of children with autism, 17 siblings of nonhandicapped children. Both groups performed CDI(Kovacs' Children Depression Inventory), RCMAS(Revised Chidren's Manifest Anxiety Scale), SPPC(Self-Perception Profile for Children), Self-esteem scale. Their mothers performed K-CBCL(Korean -Child Behavior Checklist). The results of those test were analysed by Student's-test. Results：Both social competence and total social competence subsclae scores were significantly lower in sibling group of children with autism than in control group. However, each group was not significantly different on the scores of internalizing symptom, externalizing symptom subscale of CBCL, CDI, RCMAS, Self-Perception Profile and Self-esteem scale. Conclusion : Siblings of children with autism had a lower social competence than normal control group. Group comparisons indicated that siblings of children with autism and normal children did not differ on any self-report measures such as anxiety, depression, self-concept and self-esteem. Further research using more subjects will be needed.

• Korean Journal of Social Welfare
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• v.54
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• pp.99-121
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• 2003

The purpose of this study is to explore the process that youths get involved in delinquent behavior after runaway. The experiences of runaway youths are studied interpretively, so that interactive features between situations and the youths are revealed. In this way, it is expected that directions in social services to prevent and intervene with delinquent behaviors of runaway youths can be suggested. Eleven youths who have experienced running-away participated in the in-depth interviews. Their narratives are interpreted through the procedures of interpretive interactionism by Denzin(1989). Five phases of the delinquency process have been discovered: Using personal resources, getting help from new relationships, exploring alternatives to survive, learning delinquent way of living, and living independently through delinquency. Interpreted contextually, it has been founded that delinquency is a behavior to survive and a developmental process on the street, taking place in a situation of blocked communication, nevertheless within people's networks. Thus, it is suggested that the problem of runaways are not to be treated narrowly as responsibilities of the youths themselves or their families, but to be approached from the viewpoint of providing social service systems that work as a safety network and offer alternatives for the youths to survive, to resolve their troubles, and to keep healthy lives.

• Journal of Bio-Environment Control
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• v.23 no.4
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• pp.321-328
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• 2014

This study was conducted to investigate volatile organic compounds (VOCs) of persimmon (Diospyros kaki Thunb) flower. VOCs of persimmon flower was collected via SPE (solid phase micro extraction) and determined by GC-MS according to tree age and organs such as flower and calyx. The ratio of early bloom was higher in more than 15 year old tree than other trees showing tree age was related with flowering rate. Major VOCs of persimmon flower was a-pinene, butane, caryophyllene, cubebene, lavandulol, D-limoneneylangene, ylangene, mainly included green, fruit, and floral flavors. The number of VOCs in persimmon flower was 30 compounds in 5-9 years old tree, 24 compounds in 10-14 years old tree, and 32 compounds in more than 15 years old tree. In comparison with VOCs in organs of sweet persimmon 'Fuyu' cultivar, flower has 10 compounds of VOCs and 26.35% of relative peak area, while calyx has 14 compounds and 46.28%, respectively. In astringent persimmon, flower has 6 compounds of VOCs and 17.58% of relative peak area, while calyx has 9 compounds and 50.27%, showing calyx of both cultivars has various volatile compounds. This study will contribute to provide a basic data for the fragrance industry to use the flavor of persimmon flower.

• Investigative Magnetic Resonance Imaging
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• v.12 no.2
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• pp.188-196
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• 2008

Purpose : To describe the clinical, MR imaging, and pathologic findings of pediatric meningiomas. Materials and Methods : The authors retrospectively reviewed the medical records and MR images of 16 pediatric patients with pathologically proven meningioma. Mean patient age at diagnosis was 14 years (range, 3-18). MR images were reviewed for details of lesion sizes, locations, signal intensity (SI), marginal characteristics, internal architectures, enhancements, and dural and parenchymal changes. The findings of other imaging modalities and of pathological examinations were also analyzed. Results : Mean tumor size was 5.24 cm (range, 1.3-18.1 cm) and locations were supratentorial in 12 and infratentorial in 4. SI of masses were variable, that is, high in 9, iso in 4, and low in 3 on T2 weighted images (T2WI), and low (n=11), iso (n=4), or high (n=1) on T1WI images. All lesions were visualized as well-demarcated enhancing masses. Five of the tumors were heterogeneous with cystic or necrotic components. Dural attachment was observed in 11 patients and adjacent brain edema in 10. Tumors exhibited hyperdense (n=6) or isodense (n=4) on non-enhanced CT scans, and 3 of the 7 angiograms demonstrated blood supply from the internal carotid artery. Pathologic examinations revealed the following subtypes; transitional cell (n=4), meningotheliomatous (n=4), chordoid (n=2), fibrous (n=2), clear cell (n=1), hyalinized (n=1), rhabdoid papillary (n=1), and atypical (n=1). Conclusion : Pediatric meningiomas occur usually in teenagers, have diverse pathological types, and may produce atypical imaging findings, such as, a heterogeneous internal content or findings suggestive of intraaxial tumors.

• Investigative Magnetic Resonance Imaging
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• v.12 no.2
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• pp.170-177
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• 2008

Purpose : To evaluate usefulness of MR imaging after serial brain US in the high-risk neonates before discharge of the neonatal intensive care unit. Materials and Methods : Retrospective comparison of 412 US and 121 MR scans in 121 neonates and young infants were performed. Grading of germinal matrix/intraventricular hemorrhage (GMH/IVH) was performed and presence of intracranial hemorrhage other than GMH/IVH and parencyma lesions was also analyzed. Results : Among the 242 lateral ventricles, Seven GMH and 46 IVH were additionally detected by MRI. On the other hand, 30 GMH were only detected by US. US demonstrated Grade 1/2/3/4 GMH/IVH in 24/8/13/0 ventricles each, while each grades were identified in 3, 49, 10, 2 ventricles on MR images. Other intracranial lesions additionally detected on MR images were cerebral hemorrhage (n=4), cerebellar hemorrhage (n=4), extraaxial hemorrhage (n=8), diffuse excessive signal change of the white matter (n=72), non-cavitary lesion (n=4), encephalomalacia (n=2), and ventriculomegaly (n=5). Conclusion : MR imaging could be an excellent complimentary study after serial brain US for additional detection of the intracranial pathology, particularly IVH and white matter lesions, though US would be better in follow-up of GMH in some neonates.