• Title/Summary/Keyword: 김성진

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Drug Resistance of Mycobacterium Tuberculosis in Korea (한국인 결핵환자로 부터 톨리된 인형결핵균의 약제내성)

  • Kim, Sang-Jae;Hong, Young-Pyo;Han, Yong-Chul;Kim, Sung-Jin
    • Tuberculosis and Respiratory Diseases
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    • v.38 no.2
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    • pp.99-107
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    • 1991
  • Drug resistance of M. tuberculosis has been investigated with isolates from patients screened out of the sample population of the nationwide tuberculosis prevalence surveys or from the routine cultures. The results showed a close inverse relationship between prevalence of drug resistance and efficiency of the past or current treatment regimens of NTP. Individual drug resistance also showed a close relationship with the extent of use of the relevant drugs. Drug resistance was found in 38.0% of M. tuberculosis isolates from patients found in 1965 survey and remained unchanged until it increased upto 48.0% in 1980 survey. The resistance prevalence, however, dropped to 30.8% in 1985 and further to 25.3% in 1990 survey. Such decrease was fairly well coincided with a continuous increase of the treatment efficiency (from 60% in 1984 to 77% in 1989) in 1980s. Initial drug resistance also showed a similar trend, namely 26.2% in 1965, 23.9% in 1970, 20.1% in 1975, 30.6% in 1980, 17.4% in 1985, and 15.0% in 1990. The similar figures were observed in M. tuberculosis isolates from patients diagnosed in the routine services. Higher prevalence of initial drug resistance was observed among urban patients than rural patients and among young patients than old patients. These findings signify that a continuous survey on drug resistance permits to monitor efficiency of treatment programme of the country.

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Effect of Armeniacae Semen Extracts on Human Gingival Fibroblasts and Periodontal Ligament Cells under the High Glucose Conditions (행인 추출물이 고포도당 상태의 치은섬유아세포 및 치주인대세포에 미치는 영향)

  • Na, Seong-Yoon;Kwon, Young-Hyuk;Park, Joon-Bong;Heer, Yeek;Kim, Sung-Jin
    • Journal of Periodontal and Implant Science
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    • v.30 no.1
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    • pp.77-91
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    • 2000
  • The purpose of this study was performed to evaluate the effect of Armeniacae Semen extracts on human gingival fibroblasts and periodontal ligament cells in vitro. A experiment was done to evaluate the effect of Armeniacae Semen extracts in high glucose media. $400mg/d{\ell}$ glucose was added to the culture media of all groups. In control group, the cells($4.5{\times}10^4cells/ml$) were cultured with Dulbecco's Modified Eagle's Medium contained with 10% fetal bovine serum. In experimental groups, Armeniacae Semen extracts was added to the above culture media at the final concentrations of $1{\mu}g/m{\ell}$(Test group 1) and $l0{\mu}g/m{\ell}$(Test group 2). Then each group was tested for the rate of cell proliferation at 1, 2, 5 days, protein levels at 2, 5 days, and alkaline phosphatase activity at 2, 5 days. The results were as follows ; 1. Under the high glucose condition 1)As centration of Armeniacae Semen extracts increased, the rate of cell proliferation decreased significantly in test group 2 at 5 days in human gingival fibroblasts, but increased significantly in test group 2 at 5 days in human periodontal ligament cells(P<0.05). 2)In human gingival fibroblasts, test group 2 showed significantly decreased protein levels as compared to control group at 5 days. In periodontal ligament cells, test group 1 and 2 showed not significantly increased protein levels as compared to control group at 2, 5 days(P<0.05). 3)Alkaline phosphatase activity of human periodontal ligament cells increased as concentration of Armeniacae Semen extracts increased. The test group 1and 2 showed significant increase as compared to control group at 5 days(P<0.05). From the above results, Armeniacae Semen extracts appeared to enhance cellular activities including the rate of cell proliferation, protein levels and alkaline phosphatase activity of selectively human periodontal ligament cells in high glucose media. This study suggests that Armeniacae Semen extracts seem to be able to subside the inflammation of periodontal tissue and regenerate the destructed periodontal tissue.

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Agronomic Characteristics of Sunflower (Helianthus annuus L.) Collections (해바라기 수집종의 작물학적 특성)

  • Kim, In-Jae;Nam, Sang-Young;Lee, Yun-Ho;Kim, Seong-Jin;Choi, Seong-Yel;Rho, Chang-Woo;Lee, Jung-Gwan;Song, In-Gyu;Kim, Hong-Sig
    • Korean Journal of Plant Resources
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    • v.23 no.1
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    • pp.1-6
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    • 2010
  • To evaluate agronomic characteristics for the use of biodiesel crop, 328 collections of sunflower (Helianthus annus L.) were obtained from Genebank in Rural Development Adminstration (RDA). The necessary days from seeding to emergence of collections were from 7 to 12 days, and the days to flowering were widely distributed from 55 to 86 days. Stem length ranged from 131 to 345 cm with a mean of 259 cm, and the mean maturing days were 35 days. The number of head flower was 1~23 ea per plant, and the mean size of head flower was 17.6 cm with a range from 14.7 to 21.3 cm (72.8%). The mean seed number per head flower was 1,430 ea, and the weight of seed per plant ranged from 23 to 379 g with a mean of 91.4 g. The mean seed length was 11.7 mm with a range from 9.0 to 21.5 mm, and the mean diameter was 6.4 mm. The mean weight of seed per litter, 1000 grain weight and seed weight per plant were 322.5 g, 63.3 g and 204 g, respectively. Variation of number of head per plant was largest and weight of grain per plant was large in next among growth and grain characteristics. At the results of correlation analysis among characteristics, the seed diameter was getting bigger and the days for flowering dates were prolonged in the higher stem length plant, but the days to maturing and growth duration was shortened.

Perceived Value, Satisfaction and Revisit Intention for Arboretum Visitors (수목원 방문자들의 지각된 가치, 만족 및 재방문 의도간의 관계)

  • Hong, Sung-Kwon;Kim, Jae-Hyun;Kim, Yong-Ha;Kim, Sung-Jin;Jang, Ho-Chan;Lee, Seok-Ho;Tae, Yoo-Lee
    • Journal of Korean Society of Forest Science
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    • v.99 no.4
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    • pp.517-527
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    • 2010
  • The purpose of this study was to investigate the causal relationship among perceived value, satisfaction and revisit intention for visitors of the Korea National Arboretum. Three hundred respondents were selected by quota sampling, and well-known measurement scales utilized in marketing field were adopted in order to measure three variables with some modification to apply for arboretum visitors. Results of structural equation model showed that perceived value affected visitors' satisfaction, which in turn influenced revisit intention. Specifically, "emotional value" had the most significant influence on satisfaction, followed by "value for money" and "novelty value"; however, "social value" was not an influential construct. Based on calibration results, several strategies were suggested for the effective management. Authors advised that (a)improvement of measurement scale of value, (b)inclusion of self-congruity as antecedent variable to satisfaction, (c)changing revisit intention to word-of-mouth communication as a post-purchase behavioral intention, and (d)implementation of market segmentation should be considered for future research.

Analysis of Factors Influencing Behavior of Oriental Medicine Utilization (한방의료이용 행태와 이에 영향을 미치는 요인 분석)

  • Kim Sung-Jin;Nam Chul-Hyun;Kim Jae-Don;Kim Byoung-Ha;Kim Gi-Yeol
    • Journal of Society of Preventive Korean Medicine
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    • v.8 no.1
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    • pp.89-107
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    • 2004
  • This study was conducted to analyze community residents' behavior of Oriental medicine utilization and its related factors in order to provide basic data for formulation of policies on Oriental medicine. The subjects of this study was 500 residents who lived in big or medium sized cities and towns or villages Data were collected from March, 2002 to June, 2002. The results of this study can be summarized as follows. 1) According to socio-demographic characteristics of the respondents, female was 50.3%; 'over 50 years old' 29.9%, 'over college graduate' 39.7%, 'housewife' 23.0%, 'having spouse' 62.1%, 'Buddhist' 50.8%, 'living in big cities' 59.0%, 'middle economic class' 88.1%. 2) The highest proportion of frequency of Oriental medicine utilization was over 10 times(32.5%). The respondents visited Oriental medicine institutions for taking invigorant(51.1%), treatment of diseases in muscle or bone system(30.8%), treatment of diseases in digestive system(6.3%), etc. 3) According to the reasons of utilizing Oriental medicine, the proportion of good effect was highest(36.3%). 66.8% of the respondents replied that Oriental medical fee was expensive, while 0.8% of them replied that it was not expensive. 33.3% of them thought it was proper. 4) 35.5% of the respondents replied that treatment by Oriental medicine could cause side effect and 40.3% of them replied that the side effect could be caused by taking herb medicine. 5) 62.8% of the respondents replied that they would continuously receive opinions on Oriental medicine. The score of knowledge level of treatment by Oriental medicine $6.25{\pm}2.82$ points on the basis of 14 points. 6) The variables significantly influencing utilization of Oriental medicine includes taking diseases, living in big cities, male, upper (economic class, having religion, and effect of Oriental medicine. 7) The factors affecting effect of herb medicine were effect of treatment by Oriental medicine, marital status, knowledge level of Oriental medicine, having diseases, and frequency of receiving the treatment.

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Drop reliability evaluation of Sn-3.0Ag-0.5Cu solder joint with OSP and ENIG surface finishes (OSP.ENIG 표면 처리된 기판과 Sn-3.0Ag-0.5Cu 솔더 접합부의 낙하충격 신뢰성 평가)

  • Ha, Sang-Ok;Ha, Sang-Su;Lee, Jong-Bum;Yoon, Jeong-Won;Park, Jai-Hyun;Chu, Yong-Chul;Lee, Jun-Hee;Kim, Sung-Jin;Jung, Seung-Boo
    • Journal of the Microelectronics and Packaging Society
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    • v.16 no.1
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    • pp.33-38
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    • 2009
  • The use of portable devices has created the need for new reliability criterion of drop impact tests because of the tendency to accidentally drop in the use of these devices. The effects of different PCB surface finishes (organic solderability preservative (OSP) and electroless nickel immersion gold (ENIG)) and high temperature storage (HTS) test on the drop reliability were studied. Various drop test conditions were used to evaluate a drop reliability of assemblies to endure such impact and shock load. In the case of the as-reflowed samples (no HTS test), the SAC/OSP boards exhibited a better drop impact reliability than that of SAC/ENIG. However, the reverse was true if HTS test is performed. In addition, significant decrease of drop reliability was observed for both SAC/ENIG and SAC/OSP assemblies after HTS test. It was also observed that the thickness of intermetallic compound layer do play an important role in the brittle fracture of drop test.

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Simulations of the Effect of Flow Control and Phosphate Loading on the Reduction of Algae Biomass in Gangjeong-Goryong Weir (유량 조절과 인 부하 변동에 따른 강정고령보 조류저감 효과 수치 모의)

  • Park, Dae-Yeon;Kim, Sung-Jin;Park, Hyung-Seok;Chung, Se-Woong
    • Journal of Environmental Impact Assessment
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    • v.28 no.6
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    • pp.507-524
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    • 2019
  • The purpose of this study was to validate the EFDC model for the weir pool of Gangjeong-Goryong Weir located in Nakdong River, and evaluate the effect of flow control and phosphate loading reduction on the water quality and algae biomass by group (Diatom, Green, Cyanobacteria). As a result of model validation using 2018 experimental data,the time series of water level and vertical distribution of water temperature, DO, organic matter, nitrogen, and phosphorus time series were properly simulated. Seasonal fluctuations of algae biomass by group were adequately reproduced, but the deviations between measured and simulated values were significant in some periods. As a result of scenario simulations to control the water level and flow rate, the thermal stratification was resolved as the water level was lowered and the flow rate increased. The flow velocity at which the water temperature stratification was resolved was about 0.1 m/s, which is consistent with the previous study results of Baekje Weir in Geum River. Simulations of the 2Q flow scenario showed that Chl-a decreased by 8.7% and the cell density of diatom and green algae declined. The cell density of cyanobacteria increased, however, because the high concentrations of cyanobacteria in the upstream boundary conditions directly affected downstream due to increased flow velocity. In the scenario simulation of reducing the influent phosphate load concentration (average 0.056 mg/L) to 50%, Chl-a decreased by 13.6%.The results suggest that the upstream algae concentration and phosphorus load reduction should be considered simultaneously with hydraulic control to prevent algal overgrowth of Gangjeong-Goryong Weir.

Hybrid Mobile IP Protocol for Service Session Continuity between WiBro and HSDPA (WiBro와 HSDPA 망간 서비스 연속성을 제공하기 위한 Hybrid Mobil IP 프로토콜)

  • Kim, Sung-Jin;Choi, Woo-Jin
    • 한국정보통신설비학회:학술대회논문집
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    • 2008.08a
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    • pp.223-228
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    • 2008
  • Recently, various types of wireless access networks, such as WLAN, WiBro and HSDPA, etc, have been successfully deployed by commercial service providers (i.e., KT, KTF). In this situation, there are many efforts to provide high quality of services to guarantee seamless mobility between heterogeneous networks. The IP layer mobility protocols are efficient mechanisms to provide seamless mobility between IP based heterogeneous networks as well as homogeneous networks. However, to apply IP mobility protocols in real heterogeneous networks (i.e., WiBro and HSDPA), we must consider not only the basic features of techniques of wireless access networks (i.e., Data rate, Coverage, Quality of Service) but also the problem of real environment of service provider (i.e., Expanse cost to change the access network). Due to this reason, it is difficult to satisfy required conditions by using only one IP mobility protocol in real heterogeneous networks. Therefore, in this paper, we propose an efficient mobility protocol to solve the complex problems that are occurred in real heterogeneous networks. The proposed protocol, so-called, "Hybrid Mobile IP" tries to provide a synergy effect by integrating Client Mobile IPv4 (CMIPv4) and Proxy Mobile IPv4 (PMIPv4), and using the two mobility protocols selectively according to the situation of real heterogeneous networks.

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The Mechanism of Proxy Mobile IPv4 to Minimize the Latency of Handover Using MIH Services (MIH 서비스를 활용한 Proxy Mobile IPv4의 핸드오버 지연 최소화 방안)

  • Kim, Sung-Jin;You, Heung-Ryeol;Rhee, Seuck-Ho
    • 한국정보통신설비학회:학술대회논문집
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    • 2008.08a
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    • pp.211-217
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    • 2008
  • Recently, there are many efforts to support seamless mobility in 802.11 WLANs using IP Layer mobility protocols. The IP layer mobility protocols are the most efficient mechanism to guarantee the service session continuity when IP subnet is changed during handover. Even if the IP layer mobility protocols are quite efficient, the feature of the protocols that had been designed to consider only L3 layer makes it difficult to improve the performance of hand over more and more. Nowadays, to overcome this limitation of IP mobility protocols, many researchers have worked on the mobility protocols integration of different layers (e.g., L2 layer). In this paper, we propose the enhanced Proxy MIPv4 to minimize the latency of handover using MIH protocol in 802.11 WLANs. The proposed mechanism minimizes the latency of authentication by exchanging security keys between Access Routers during handover. Moreover, it also minimizes packet losses by Inter-AP Tunneling and data forwarding.

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필름 스피커 적용을 위한 PZT/polymer 복합체의 후막 제조 및 압전 특성 평가

  • Son, Yong-Ho;Eo, Sun-Cheol;Kim, Seong-Jin;Gwon, Seong-Yeol;Gwon, Sun-Yong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.11a
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    • pp.346-346
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    • 2007
  • 압전세라믹 재료는 현재 압전 변압기, actuator, transducer, sensor, speaker 등에 광범위하게 이용이 되고 있다. 이 중에서 압전세라믹 소결체를 이용한 스피커의 제조는 가공이 까다롭고, 대형의 크기로 제작 시 소자가 깨지는 등의 많은 제약을 받고 있으며, 저음 특성이 떨어져 응용 범위가 한정되어 있다. 따라서 최근에는 이러한 단점을 극복하기 위하여 세라믹/고분자 복합체를 이용한 필름 스피커를 제작하고자 시도하고 있다. 이러한 세라믹/고분자 0-3형 압전 복합체를 이용할 경우, 제품의 경량화를 실현할 수 있고, 크기나 환경의 영향을 거의 받지 않으므로, 고기능성 스피커로의 응용에 적합할 것으로 보인다. 따라서 본 연구에서는 PZT계의 세라믹와 PVDF, PVDF-TrFE, Polyester, acrylic resin 등의 여러 고분자 물질과의 복합체를 제조하여 압전특성을 평가하였다. 본 실험은 먼저 $(Pb_{1-a-b}Ba_aCd_b)(Zr_xTi_{1-x})_{1-c-d}(Ni_{1/3}Nb_{2/3})_c(Zn_{1/3}Nb_{2/3})_dO_3$ (이하 PZT라 표기)의 최적화 조성을 선택하여, $1050^{\circ}C$에서 소결된 분말을 48시간 ball milling방법 로 약 $1{\mu}m$ 크기로 분쇄하였다. 고분자 물질들은 알맞은 용제들을 선택하여 녹였다. 그 다음 소결된 PZT분말과 고분자를 50:50, 60:40, 65:35, 70:30등의 무게 분율로 혼합하고, 분산제, 소포제 등을 첨가하여 3단 roll mill을 이용하여 충분히 분산시켜 페이스트 (Paste)를 제조하였다. 제조된 페이스트를 ITO가 코팅된 PET필름 위에 스크린 프린팅 법을 사용하여 인쇄하여 $120^{\circ}C$에서 5분간 건조하였다. 코팅된 복합체의 두께는 약 $80{\mu}m$ 정도로 측정되었다. Ag 페이스트를 이용한 상부 전극 형성에도 스크린 프린팅 법을 적용하였다. 이를 $120^{\circ}C$에서 4 kV/mm의 DC 전계로 분극 공정을 수행한 후 전기적 특성을 평가하였다. 유전특성을 조사하기 위해서 LCR meter (EDC-1620)를 사용하였고, 시편의 결정구조는 XRD (Rigaku; D/MAX-2500H)을 통해 분석하였으며, 전자현미경(SEM)을 이용하여 미세구조를 분석하였다. 압전 전하상수$(d_{33})$ 값은 APC 8000 모델을 이용하여 측정하였다. PZT의 혼합비가 증가할수록 비유전율 및 압전 전하 상수 등의 전기적 특성이 증가되었다. 또 여러 고분자 물질 중에서 PVDF-TrFE 수지가 가장 우수한 특성을 보였다. 이는 PVDF-TrFE 수지가 압전성을 나타내기 때문인 것으로 판단되었다.

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