• Title/Summary/Keyword: 기하 활성 모델

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Tracking of Continuously Acting Hearts Using a Geometric Active Contour Model (기하 활성 모델을 이용한 연속적 심장 운동 추적)

  • 김성곤
    • Journal of the Institute of Convergence Signal Processing
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    • v.3 no.4
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    • pp.17-22
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    • 2002
  • This paper used an active contour model which was based on level set algorithms and bidirectional curve evolution theory in order to track the shape of the heart acting continuously. Most active contour models would be failed in boundary extraction because of their unstable movement in the edge gap locations. In this paper, we suggest a new active contour model using only image intensity value and additional constraint needed for stable extraction. Our model was successfully run on either shape extraction or object tracking without any position constraints of initial curve. Also demonstrated stable movements and showed good results at weak or missing boundary locations.

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2D-QSAR and HQSAR Analysis on the Herbicidal Activity and Reactivity of New O,O-dialkyl-1-phenoxy-acetoxy-1-methylphosphonate Analogues (새로운 O,O-dialkyl-1-phenoxyacetoxy-1-methylphosphonate 유도체들의 반응성과 제초활성에 관한 2D-QSAR 및 HQSAR 분석)

  • Sung, Nack-Do;Jang, Seok-Chan;Hwang, Tae-Yeon
    • The Korean Journal of Pesticide Science
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    • v.11 no.2
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    • pp.72-81
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    • 2007
  • Quantitative structure-activity relationships (QSARs) on the pre-emergency herbicidal activity and reactivity of a series of new O,O-dialkyl-1-phenoxyacetoxy-1-methylphosphonates (S) analogues against seed of cucumber (Cucumus Sativa) were discussed quantitatively using 2D-QSAR and HQSAR methods. The statistical values of HQSAR model were better than that of 2D-QSAR model. From the frontier molecular orbital (FMO) interaction between substrate molecule (S) and $BH^+$ ion (I) in PDH enzyme, the electrophilic reaction was superior in reactivity. From the effect of substituents, $R_2$-groups in substrate molecule (S) contributed to electrophilic reaction with carbonyl oxygen atom while X, Y-groups contributed to nucleophilic reaction with carbonyl carbon atom. And the influence of X,Y-groups was more effective than that of $R_2$-groups. As a results of 2D-QSAR model (I & II) and atomic contribution maps with HQSAR model, the more length of X, Y-groups is longer, the more herbicidal activity tends to increased. And also, the optimal ${\epsilon}LUMO$ energy, $({\epsilon}LUMO)_{opt.}$=-0.479 (e.v.) of substrate molecule is important factor in determining the herbicidal activity. It is predicted that the herbicidal activity proceeds through a nucleophilic reaction. From the analytical results of 2D-QSAR and HQSAR model, it is suggested that the structural distinctions and descriptors that contribute to herbicidal activities will be able to applied new herbicide design.

Intensity Information and Curve Evolution Based Active Contour Model (밝기 정보와 곡선전개 기반의 활성 모델)

  • Kim, Seong-Kon
    • The KIPS Transactions:PartB
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    • v.10B no.5
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    • pp.521-526
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    • 2003
  • In this paper, we propose a geometric active contour model based on intensity information and curve evolution for detecting region boundaries. We put boundary extraction problem as the minimization of the difference between the average intensity of the region and the intensity of the expanding closed curves. We used level set theory to implement the curve evolution for optimal solution. It offered much more freedom in the initial curve position than a general active contour model. Our methods could detect regions whose boundaries are not necessarily defiened by gradient compared to general edge based methods and detect multiple boundaries at the same time. We could improve the result by using anisotropic diffusion filter in image preprocessing. The performance of our model was demonstrated on several data sets like CT and MRI medical images.

Adsorption Analysis of Benzene Vapor in a Fixed-Bed of Granular Activated Carbon (활성탄 충전층에서 벤젠 증기의 흡착특성)

  • Kim, Seong-Soo;Kim, Jong-Hyun;Park, Sang-Wook
    • Korean Chemical Engineering Research
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    • v.47 no.4
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    • pp.495-500
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    • 2009
  • Activated carbon was used as an adsorbent to capture benzene vapor from gaseous stream of nitrogen in a fixed-bed to obtain the breakthrough data. The deactivation model is used to analyze the adsorption kinetics of benzene vapor using the experimental breakthrough data. The experimental breakthrough data are fitted very well to the deactivation model than the adsorption isotherm models in the literature.

2D-QSAR and HQSAR Analysis on the Herbicidal Activity of New Cyclohexanedione Derivatives (새로운 Cyclohexanedione계 유도체의 제초활성에 관한 2D-QSAR 및 HQSAR 분석)

  • Kim, Yong-Chul; Hwang, Tae-Yeon;Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.12 no.1
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    • pp.9-17
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    • 2008
  • QSARs (Quantitative structure-activity relationships) between a series of new cyclohexanedione derivatives (5-benzofuryl-2-[1-(alkoxyimino)-alkyl]-3-hydroxycyclohex-2-en-1-ones) and their herbicidal activity against Rice plant (Oryza sativa L.) and Barnyard grass (Echinochloa crus-galli.) were discussed quantitatively using 2D-QSAR and holographic (H) QSAR methods. Generally, the HQSAR models have better predictability and fitness than the 2D-QSAR models. The herbicidal activities against Barnyard grass with 2D-QSAR II model were dependent upon Balaban indice (BI) of molecule and hydrophobicity of $R_1$ and $R_3$ group. And also, the $R_3=ethyl$ group, according to the information of the optimized HQSAR IV model, was more contribute to the herbicidal activities against Rice plant, while the 5-(cyclohex-3-enyl)-2,3-dihydrobenzofuran ring part was not contribute to the herbicidal activities against two plants.

CoMFA Analyses on the Fungicidal Activity with N-phenylbenzensulfonamide Analogues against Gray Mold (Botrytis cinerea) (잿빛곰팡이균(Botrytis cinerea)에 대한 N-phenylbenzenesulfonamide 유도체들의 살균활성에 관한 CoMFA 분석)

  • Hwang, Tae-Yeon;Kang, Kyu-Young;Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.12 no.2
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    • pp.111-117
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    • 2008
  • The comparative molecular field analysis (CoMFA) for the fungicidal activity with N-phenylbenzenesulfonamide analogues (1-45) against gray mold (Botriyts cinerea) were studied quantitatively. The statistical values of CoMFA models had much better predictability and fitness than those of comparative molecular similarity indices analysis (CoMSIA) models. The statistical values of the optimized CoMFA I model were predictablity, $r^2_{cv.}(or\;q^2)=0.457$ and correlation coefficient, $r^2_{ncv.}=0.959$, and their fungicidal activity was dependent on the steric field (52%) and electrostatic field (35.6%) of the substrate molecules. And also, it was found that the optimized CoMFA I model with the sensitivity to perturbation ($d_q^{2'}/dr^2_{yy'}=0.898$) and prediction ($q^2=0.346$ & SDEP=0.614) produced by a progressive scrambling analysis was not dependent on chance correlation. From the results of graphical analyses on the contour maps with the optimized CoMFA I model, it is expected that the $R_3$ and $R_4$-substituents on the N-phenyl ring as steric favor group and para-substituents ($R_1$) on the S-phenyl ring as steric disfavor group will contribute to the fungicidal activity. Therefore, the optimized CoMFA I model should be applicable to the prediction of the fungicidal activities against gray mold.

Interpretation of Simultaneous Nitrification & Denitrification Reaction by Modifying Activated Sludge Models(ASMs) (활성슬러지 모델 수정을 통한 동시 질산화.탈질 반응 해석)

  • Kim, Hyo-Su;Kim, Ye-Jin;Lee, Sung-Hak;Moon, Tae-Sup;Choi, Jae-Hoon;Kim, Chang-Won
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.2
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    • pp.199-206
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    • 2008
  • Simultaneous nitrification and denitrification means that nitrification and denitrification occur concurrently in the same reaction vessel under low DO concentration. Some mathematical models developed to simulate simultaneous nitrification and denitrification reaction, but they have the complex model structures or have limitations of model application. To solve these problems, if possible that predict the behavior of simultaneous nitrification and denitrification reaction by activated sludge model, structures of the model is less complex than previous models and applies the various operation conditions. But original activated sludge models have difficulties in representing the denitrification reaction under aerobic condition. So the aim of this study is to interpret simultaneous nitrification and denitrification reaction by modifying activated sludge model. Original activated sludge model No.1(ASM1) was selected and modified. The simulation result in modified ASM1 predicted appropriately for the measured data. This indicates the structures of ASM1 are properly improved for interpretation of simultaneous nitrification and denitrification reaction.

Vision-based Mobile Robot Control System (비전 기반의 모바일 로봇 제어 시스템)

  • Chang Jae Sik;Kim Eun Yi;Jang Sang Su;Kim Hang Joon
    • Proceedings of the Korean Information Science Society Conference
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    • 2005.07b
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    • pp.781-783
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    • 2005
  • 본 논문은 손 모양 인식을 이용한 비전 기반의 보행 로봇 제어 시스템을 제안한다. 손의 모양을 인식하기 위해서 움직이는 카메라 영상으로부터 정확한 손의 경계선물 추출하고 추적하는 일이 선행되어야 한다. 따라서 본 논문에서는 민 시프트 방법을 사용한 활성 윤곽선 모델 기반의 추적 방법을 제안한다. 제안된 시스템은 손 추출기, 손 추적기, 손 모양 인식기 그리고 로봇 제어기, 4개의 모들로 구성된다. 손 추출기는 영상에서 미리 정의된 손의 모양을 가지는 피부색 영역을 추출한다. 추출된 손의 추적은 활성 윤관선 모델과 민 시프트 방법을 사용하여 실행된다. 그 후 Hue moments를 사용하여 추적된 손의 모양을 인식한다. 제안된 방법을 평가하기 위해서 본 논문에서는 2족 보행 로봇 KHR-1에 제안된 방법을 적용 한다.

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Performance Analysis of Modified PRMA: PRHMA(Packet Reservation Hold Multiple Access) (변형된 PRMA의 성능분석)

  • 김환의;김덕년
    • Proceedings of the Korea Institute of Convergence Signal Processing
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    • 2000.08a
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    • pp.73-76
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    • 2000
  • 본 논문에서는 다중접속 프로토콜인 PRMA의 변형된 모델에 대해서 다뤘다. 기존의 PRMA에서는 초기 엑세스시 얻은 슬롯을 휴지기에 잃게 되므로 매 활성기마다 다시 슬롯을 엑세스함으로써 추가적인 패킷의 drop이 발생하는 반면, 변형된 모델에서는 슬롯예약을 유지하기 위한 제어미니슬롯을 사용함으로써 초기 엑세스 이후의 추가적인 패킷 drop이 발생하지 않는다.

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3D-QSAR Analyses on the Inhibition Activity of 4-Hydroxybenzyl alcohol Analogues Against Tyrosinase (4-Hydroxybenzyl alcohol 유도체들의 Tyrosinase 활성 저해에 대한 3D-QSAR 분석)

  • Kim, Sang Jin;Sung, Nack Do
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.4
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    • pp.329-335
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    • 2013
  • Three-dimensional quantitative structure-activity relationships (3D-QSARs) models between the substituents with changing groups ($R_1$ & $R_2$) of 4-hydroxybenzyl alcohol (4-HBA) derivatives as substrate molecule and their inhibitory activities against tyrosinase were derived and discussed quantitatively. The optimized CoMSIA FF model showed the best predictability and fitness ($r^2$ = 0.858 & $q^2$ = 0.951). The contour maps of the optimized CoMSIA FF model showed that, the inhibitory activities of the analogues against tyrosinase were expected to increase when hydrophobic (Hy) favor, negative charge (E) favor, steric (S) disfavor and hydrogen bond donor (HD) disfavor groups were substituted at the $R_2$ position. When the hydrogen bond donor (HD) favor groups were substituted at the $R_1$ position, it is predicted that the substituents will be able to increase the inhibitory activity.