• Title/Summary/Keyword: 기미

Search Result 171, Processing Time 0.024 seconds

Sudden Death Caused by Clostridium perfringens Type D Enterotoxemia in Feedlot Cattle (비육 우의 Clostridium perfringens D 형 장독 혈증에 의한 폐사)

  • Jang, Seong-Jun;Do, Sun-Hee;Ki, Mi-Ran;Hong, Il-Hwa;Park, Jin-Kyu;Cho, Yu-Jeong;Ji, Ae-Ri;Park, Se-Il;Park, Sang-Joon;Kim, Tae-Hwan;Kwak, Dong-Mi;Jeong, Kyu-Shik
    • Journal of Life Science
    • /
    • v.20 no.5
    • /
    • pp.639-643
    • /
    • 2010
  • Sudden deaths have occurred in feedlot cattle with marked necro-hemorrhagic enteritis of the jejunum, ileum and colon. Suckling beef calves are the most frequently affected. Over-consumption of large amounts of milk, inadequate colostrum intake, chilling and stress are conducive to the development of enterotoxemia. Enterotoxemia caused by Clostridium perfringens type D mostly occurs following a sudden change of diet, particularly to feeds made richer in order to grow the cattle to market weight in feedlots. During July 2006, sudden deaths of cattle occurred in the Youngcheon regional area of Gyeongbuk province. There were no significant clinical signs except anorexia, depression, intermittent diarrhea and mild respiratory failure. Histological findings revealed a prominent intranuclear inclusion as well as infiltration of the globular leukocytes in various organs including the heart, kidneys, liver, spleen and lymph nodes. Spleen and lymphatic tissues showed lymphatic necrosis and a starry sky appearance. In the submucosa of the small intestines, basophilic aggregation was detected with massive infiltration of the globular leukocytes and eosinophils. Gram staining for the tissue sections containing inclusions of the small intestines revealed a positive histochemical reaction. Taken together, we suggest that Clostridium perfringens type D-induced enterotoxemia is determined to be the cause of sudden death of feedlot cattle.

Effect of Ulmus macrocapa Ethanolic Extracts on Anti-oxidant Activity and Melanin Synthesis in B16F1 Cells (B16F1세포에서 항산화 활성 및 멜라닌 합성에 대한 유백피 에탄올 추출물의 효능)

  • Kwon, Eun-Jeong;Park, Hye-Jung;Kim, Moon-Moo;Lee, Kyeong Rok;Hong, Il;Lee, Do Gyeong;Oh, Yunghee
    • Journal of Life Science
    • /
    • v.24 no.9
    • /
    • pp.946-951
    • /
    • 2014
  • Melanin plays a key role in the protection of skin from ultraviolet light that generates reactive oxygen species (ROS), such as superoxide, hydroxyl radical, singlet oxygen and hydrogen peroxide. However, the ROS leading to the oxidation of lipids, proteins and DNA are involved in the overproduction of melanin that is known to cause melasma, age spots and freckles. Among the herb medicines, Ulmus macrocarpa used in this study was reported to contain flavonoids as a main component. The aim of this study is to investigate the whitening and anti-oxidant effects of Ulmus macrocarpa ethanolic extracts (UMEE) in B16F1 cells. UMEE below $3.12{\mu}g/ml$ did not show cytotoxicity. In an anti-oxidant experiment, UMEE showed not only high reducing power and scavenging activity on DPPH, but it was also observed that UMEE exhibit an inhibitory effect on lipid peroxidation. UMEE did not display an inhibitory effect on tyrosinase activity in vitro. However, UMEE inhibited melanin synthesis in B16F1 cells. In addition, UMEE reduced the expression levels of tyrosinase and tyrosinase-related protein-2 (TRP-2), which are key enzymes in melanogenesis. These results indicate that UMEE exert a whitening effect through the inhibition of both tyrosinase and TRP-2 expressions as well as anti-oxidant activity, suggesting that UMEE could have the functional potential for a whitening effect on the skin.

인터넷 기반 원스톱서비스 시스템 개발에 관한 연구+ -수출컨테이너화물 원스톱서비스 시스템 개발-

  • 박남규;최형림;김현수;박영재;조재형;이철우
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
    • /
    • 1999.10a
    • /
    • pp.299-308
    • /
    • 1999
  • 오늘날 우리 나라가 당면한 최우선 경제과제중 하나는 물류부분의 혁신을 통한 국가경쟁력 강화라고 할 수 있으며, 이를 위해 정부도 1993년 물류체계 개선을 위한 장기구상으로 ‘화물유통체계 개선 10개년 기본계획’을 수립하여 적극 추진 중에 있다. 그러나 이러한 노력에도 불구하고 PORT-MIS사용자를 상대로 한 설문조사에서는 선박입출항 업무 관련 서류의 40%, 항만시설 사용 업무와 관련된 서류의 31%, 하역업무 관련 서류의 10%만이 EDI를 활용하고 있었다. EDI 활용이 저조한 사유로는 전송시간이 많이 걸리며, EDI 소프트웨어가 작동되지 않으며, 수신확인이 되지 않기 때문이라 응답을 하였다. 이처럼 오늘날 항만물류산업이 겪고 있는 물류 데이터 흐름이 단절적 현상은 시간이 흐를수록 해결 될 기미가 보이고 있지 않다. 따라서 본 논문에서는 우리 나라가 겪고 있는 물류관련 업무를 한번의 데이터 입력으로 해결할 수 있는 원스톱 서비스 시스템개발을 목표로 우선 PORT-MIS EDI 업무를 처리할 수 있는 시스템을 구축하였다. 이는 향후 화주, 운송사, 선사, 포워더, 창고업자,하역회사, 철도청, 화물터미널, 컨테이너 터미널, 해양수산청, 관세청, 출입국관리사무소, 검역소 사이에 서로 교환되는 적하목록, Booking List, 컨테이너 Pick up정보, 위험물 정보, COPINO 정보를 비롯하여 대 관세청 신고 등 수출컨테이너 화물업무의 전반적인 영역으로까지 쉽게 확대할 수 있을 것이다. 본 연구결과 구축된 시스템은 원천정보를 중앙의 통합데이터베이스에 저장하여 이를 사용자의 요구에 의해 인터넷을 통해 전달하는 FTP와 웹 EDI 방식을 결합한 하이브리드 형태이다.CS Cell 방식에 의한 위치결정방식을 채택하였는데, 이것은 PCS망을 기반으로 데이터를 주고받이며 인터넷 단말기로 확장 가능한 PCS 단말기를 사용해서 위치추적을 하는 시스템이다. 이러한 시스템을 선정하게된 배경은 단말기아 망 이용료의 가격이 저렴하여 현실적으로 트럭이 쉽게 부착할 수 있다는 장점이 있으며 나아가 인터넷 단말기를 활용하여 차량과 관제센터사이에 메시지 전송 등 부가적인 서비스가 가능하기 때문이다.비교한 결과 토사 유출 억제효과는 한지형과 나지형잔디들의 혼합형(MixtureIII)과 자생처리구(MixtureV), Italian ryegrass와 자생식물의 혼합형(MixtureIV)등에서 비교적 낮은 수치를 토사유출량을 기록하였다. 이러한 결과는 자생식물들이 비록 초기생육속도는 외래도입초종에 떨어지지만 토사유출의 억제효과면에서는 이들 외래초종에 필적할 수 있음을 나타낸다고 할 수 있겠다.중량이 약 115kg/$m^2$정도로 나타났다.소 들(환경의 의미, 사람의 목적과 지식)보다 미학적 경험에 주는 영향이 큰 것으로 나타났으며, 모든 사람들에게 비슷한 미학적 경험을 발생시키는 것 이 밝혀졌다. 다시 말하면 모든 사람들은 그들의 문화적인 국적과 사회적 인 직업의 차이, 목적의 차이, 또한 환경의 의미의 차이에 상관없이 아름다 운 경관(High-beauty landscape)을 주거지나 나들이 장소로서 선호했으며, 아름답다고 평가했다. 반면에, 사람들이 갖고 있는 문화의 차이, 직업의 차 이, 목적의 차이, 그리고 환경의 의미의 차이에 따라 경관의 미학적 평가가 달라진 것으로 나타났다.corner$적 의도에 의한 경관구성의 일면을 확인

  • PDF

Clogging Potential in Constructed Vertical Flow Wetlands Employing Different Filter Materials for First-flush Urban Stormwater Runoff Treatment (도시 초기 강우유출수 처리를 위한 수직흐름습지에서 여재별 폐색 잠재성 분석)

  • Chen, Yaoping;Guerra, Heidi B.;Kim, Youngchul
    • Journal of Wetlands Research
    • /
    • v.20 no.3
    • /
    • pp.235-242
    • /
    • 2018
  • The function of vertical subsurface flow wetlands can potentially be reduced with time due to clogging and are often assumed to be occurring when ponding and overflow is observed during rainfall. To investigate their clogging potential, three pilot-scale vertical subsurface flow (VSF) wetland systems were constructed employing woodchip, pumice, and volcanic gravel as main media. The systems received stormwater runoff from a highway bridge for seven months, after which the media were taken out and divided into layers to determine the amount and characteristics of the accumulated clogging matters. Findings revealed that the main clogging mechanism was the deposition of suspended solids. This is followed by the growth of biofilm in the media which is more evident in the wetland employing woodchip. Up to more than 30% of the clogging matter were found in the upper 20 cm of the media suggesting that this layer will need replacement once clogging occurs. Moreover, no signs of clogging were observed in all the wetlands during the operation period even though an estimation of at least 2 months without clogging was calculated. This was attributed to the intermittent loading mode of operation that gave way for the decomposition of organic matters during the resting period and potentially restored the pore volume.

The effect of notification disposition in the current juvenile justice system from the perspective of institutionalized children's welfare (시설보호아동의 복지 관점에서 본 소년법상 통고제도)

  • Lee, Hyung-Seob;Jung, Sun-wook
    • Journal of the Korean Society of Child Welfare
    • /
    • no.56
    • /
    • pp.69-99
    • /
    • 2016
  • Taking the perspective of children's welfare, this study aimed at critically analyzing the system of notification disposition which institutionalized children have experienced. Notification disposition is a juvenile justice process that, when a child (10 th 18 years old ) has been delinquent or is at risk for delinquency, is initiated without investigation or prosecution procedures by direct notification to a judge from the caregivers, school principals, chief probation officers, or directors of child care institutions. The data used in the analysis included case records of probation offices, and court sentencing documents of juvenile protective dispositions. Results showed that notification cases were initiated by directors of child shelters/care institutions. The most common reasons of notification were theft, runaway, physical violence, drinking, and smoking. Furthermore, there were more controversial reasons, such as "bad influence on another institutionalized children", "showing no remorse", "no sense of guilt"and "challenge of rearing in institutions" Based on the results, we discussed three problematic aspects of the direct notification system by directors of childcare institutions : (1) too much reliance on the judicature judgment of juvenile court; (2) less stability of the judicial status of notified children, and (3) inadequacies of the notifying eligibility for directors of child care institutions.

The Effects of Ginseng and American Ginseng on General Symptom in Koreans and Chineses - Double-blind Randomized Controlled Trials - (한국인과 중국인에서 인삼과 서양삼 복용후 전신 증상 -이중맹검 무작위배정 임상시험-)

  • Seo, Jung-Cjul;Han, Sang-Won;Byun, Joon-Seok;An, Hee-Duk;Han, Il-Do;Cho, Geon-Ho;Leem, Kang-Hyun;Heo, Zheng-Jie;Yi, Jinglin;Jin, Mingxiu
    • Journal of Ginseng Research
    • /
    • v.29 no.1
    • /
    • pp.27-36
    • /
    • 2005
  • In East-South Asia it has been said that ginseng(Panax ginseng) induces flushing and epistaxis, whereas American ginseng(Panax quinquefolius) dosen't. This study was designed to find out if ginseng really could increase flushing and epistaxis, compared with American ginseng. Double-blind randomized controlled trials on general symptom, such as flushing and epistaxis, of ginseng and American ginseng in Koreans and Chinese were performed by questionnaire. There was no significant accident or improvement in Koreans. But in Chinese dried mouth was significantly observed in placebo group and chest discomfort was significant in placebo group and American ginseng(4 years) group. In addition in Chinese chest discomfort was significantly observed in American ginseng(4 years) group and American ginseng(6 years) group. It was revealed that ginseng might not increase flushing and epistaxis.토양환경학회 홈페이지 ( http://www.kossge.or.kr ) 을 참조하십시오.

Identity of thermogenic reaction to Korean ginseng through bibliography - Focusing on oriental medicine interpretation (서지학적 고증을 통한 인삼 승열작용의 정체성 - 한의학적 해석을 중심으로)

  • Ko, Sungkwon
    • Journal of Ginseng Culture
    • /
    • v.3
    • /
    • pp.119-131
    • /
    • 2021
  • The purpose of this study was to explore the characteristics of and solution to thermogenic reactions to Korean ginseng through bibliographic research. A review of bibliography on the thermogenic reaction induced by ginseng indicated that people who lack fluids, have fever in lungs, a stuffy chest, coughing up sputum, a strong pulse, and constipation due to fever in the stomach may exhibit such a reaction. In the herbal medicine book of the Qing Dynasty, Bon-Cho-Jeong-Ui (本草正義) recorded that wild simulated ginseng is slightly cold and replenishes the body's liquid reserves. The book also describes the field cultivated ginseng is slightly warm and enhancing stamina. Bon-Kyung-Bong-Won (本經逢源), Bon-Cho-Pyon-Dok (本草便讀), and Bon-Cho-Jeong-Ui were published authors in the Qing Dynasty, and they explained that ginseng fine root is bitter, supplements bodily fluids, and can be easily ingested because it is cold. Wol-Ji-In-Sam-Jeon (月池人蔘傳) and Bon-Cho-Bi-Yo (本草備要) described fresh ginseng assweet, bitter, and slightly cold in the Ming and Qing Dynasties, respectively. On the basis of this bibliographic description, the thermogenic reaction induced by Korean ginseng can be overcome by using ginseng fine root, fresh ginseng, or wild simulated ginseng. These ginseng radices are slightly cool, replenish human bodily fluids, and show the physiological effects of easy ingestion properties.

Anti-melanogenic Effects of Cnidium japonicum in B16F10 Murine Melanoma Cells (B16F10 피부 흑색종세포에서 갯사상자 추출물의 멜라닌 합성 저해 효과)

  • Jo, Hyun Jin;Karadeniz, Fatih;Oh, Jung Hwan;Seo, Youngwan;Kong, Chang-Suk
    • Journal of Life Science
    • /
    • v.32 no.5
    • /
    • pp.331-339
    • /
    • 2022
  • Melanin is a pigment produced by melanocytes to protect the skin from external stimuli, mainly ultraviolet (UV) rays. However, abnormal and excessive production of melanin causes hyperpigmentation disorders, such as freckles, age spots, and discoloration. Natural cosmeceuticals are a new trend for treating or preventing hyperpigmentation due to fewer side effects and biocompatibility. In this context, the current study focused on Cnidium japonicum, a halophyte with several uses in folk medicine, to evaluate its potential as a skin-whitening agent. The effect of C. japonicum extract (CJE) on melanin production was analyzed in melanogenesis-stimulated B16F10 melanoma cells. The results showed that CJE successfully inhibited the oxidation of tyrosine and L-DOPA by tyrosinase and subsequently decreased the production of the key enzymes responsible for melanin production: tyrosinase, tyrosinase-related protein-1, and protein-2. This effect was confirmed by decreased intracellular and extracellular melanin levels in B16F10 melanoma cells after CJE treatment. Further experiments to elucidate the action mechanism revealed that CJE treatment suppressed melanin production by inhibiting the activation of glycogen synthase kinase 3 β (GSKβ)/β-catenin and protein kinase A (PKA)/cAMP-response element binding protein (CREB) pathways, which are the upstream activators of melanogenesis. In conclusion, the present study suggests that C. japonicum is a potential natural source of bioactive substances for the development of novel cosmeceuticals that can act against hyperpigmentation.

A Feasibility Study on the Hour Setting in Almanac (역법에서의 시진(時辰) 설정에 대한 타당성 논의)

  • Cheong-Ha Lee;Sun-Ok Shin
    • Industry Promotion Research
    • /
    • v.8 no.2
    • /
    • pp.119-132
    • /
    • 2023
  • The purpose of this paper is to re-establish the concept of Eastern time, which is used in Myeongliology and Kimun-dungap, and to discuss the use of real-time of the sun according to the birth area, the selection of real-jasi between night-jasi and real-jasi, and the exact meaning of birth time. The conventional use of time in Korean society uses Tokyo as standard time and uses a time system in which a new day begins at midnight. Howev er, what is important is not social univ ersality but the time and space of the univ erse where I was born, which is the center of the universe, should be the standard of my fate, so I have to use the longitude of the place where I was born to determine my exact time. Also it is argued that real-jasi should be selected for the selection problem of night-jasi and real-jasi, which has long been a controversial topic in Myeongliology, because the flow of cosmic energy is signaled an hour ahead. To secure the validity of setting such time, a case analysis was conducted using the time adjustment method through the spread of Kimun-dungap. Through in-depth interviews with the analysis subjects, the lives of the past were collected by date and time, and then Kimun-dungap checked whether the timing of each life event was accurate.

An Exploratory Study of Indifference toward Fine Arts among Korean Middle-Class through a Ground Theory Method (순수예술 무관심 현상에 대한 탐색적 연구 - 근거이론 분석방법을 통한 접근법 -)

  • Park, Min-gwon;Hyun, Eunjung
    • Korean Association of Arts Management
    • /
    • no.52
    • /
    • pp.5-37
    • /
    • 2019
  • Despite a copious volume of work on the relationship between social class and cultural consumption, scholars have paid scant attention to the increasingly apparent observation that a vast majority of the population exhibits indifference toward fine arts regardless of one's socio-economic status. Much of the prior literature on cultural consumption has treated the public's indifference to fine arts not as a distinct analytical category that deserves an explanation of its own, but simply as the opposite of "likes" or the act of consumption, let alone being disentangled from the concept of "dislikes" in taste-formation and consumption behavior. In this paper, we suggest that the seemingly increasing trend toward indifference to fine arts, especially among those who are part of the well-educated and economically well-off, merits close scholarly attention on its own term. As an initial step toward this endeavor, we explore the factors behind indifference toward fine arts among Korean middle-class, using the ground theory method. Our interview findings reveal that much of indifference toward fine arts is attributable to the lack of tastes in fine arts and artistic competence. Our results suggest that research drawing on Bourdieu's theory and Peterson's omnivore hypothesis needs to be further revised through an in-depth investigation of the institutional and societal contexts where art education takes place in Korea. We discuss the implications of our findings for policy-making in the cultural and artistic sphere.