• Journal of the Korean Society of Radiology
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• v.18 no.2
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• pp.127-133
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• 2024

The elbow joint is made up of three different bones. X-rays or other radiological exams are commonly used to diagnose elbow injuries or disorders caused by physical activity and external forces. Previous research on the elbow joint reported a new examination method that meets the imaging evaluation criteria in the tilt position by Z-axis elevation of the forearm. Therefore, this study aims to design an optimized instrument and develop an aid applicable to other upper extremity exams. After completing the 2D drawing and 3D modeling design, the final design divided into four parts was fabricated with a 3D printer using ABS plastic and assembled. The developed examination aid consists of a four-stage Z-axis elevation tilt angle function (0°, 5°, 10°, and 15°) and can rotate and fixate 360° in 1-degree increments. It was designed to withstand a maximum equivalent stress of 56.107 Pa and a displacement of 1.6548e-5 mm through structural analysis to address loading issues caused by cumulative frequency of use and physical utilization. In addition to X-ray exams of the elbow joint, the developed aid can be used for shoulder function tests by rotating the humerus and also be applied to MRI and CT exams as it is made of non-metallic materials. It will contribute to the accuracy and efficiency of medical imaging diagnosis through clinical applications of various devices and medical imaging exams in the future.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.11a
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• pp.475-478
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• 2023

컴퓨터 단층촬영(CT)을 활용한 골격근 단면적은 근감소증과 관련된 기능을 평가하는 데 사용된다. 일반적인 근감소증 연구는 요추 3번의 골격근량을 주로 보지만 암 또는 폐절제술과의 상관관계를 예측하기 위한 다양한 연구에서는 흉추 4번, 7번, 8번, 10번, 12번 다양한 수준의 골격근량으로 연구를 진행하고 있음을 알 수 있다. 본 논문에서는 흉부와 복부 CT 영상에서 근감소증 진단을 위해서 흉추와 요추의 영역별 슬라이스를 검출하기 위해서 CNN 구조의 EfficientNetV2를 전이학습하여 인공지능 모듈을 개발하였다. 인공지능 모듈은 전체 흉부 및 복부 CT 영상에서 Cervical, T1, T2, T3, T4, T5, T6, T7, T8, T9, T10, T11, T12, L1, L2, L3, L4, L5, Sacral 총 19 클래스를 검출하도록 하였다. Test 데이터셋을 사용하여 Confusion Matrix와 Grad-CAM으로 모델의 정확도를 시각화하여 보였으며 검증으로 인공지능 모듈의 정확성을 측정하였다. 끝으로 우리가 개발한 다기관 공동연구 지원플랫폼에 적용하여 시각화된 결과를 보였다.

• Journal of the Korean Society of Radiology
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• v.85 no.1
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• pp.161-170
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• 2024

Purpose To assess the safety and feasibility of intentionally positioning the catheter tip in the right atrium (RA) without an abutment during implantation of a totally implantable venous access port (TIVAP). Materials and Methods We enrolled 330 patients who had undergone TIVAP implantation between January and December 2016 and postoperative chest CT. The TIVAP was placed using the single-incision technique to access the axillary vein directly from the incision line. To position the catheter tip in the RA without abutment, blood return was checked before cutting. Catheter length and complications were evaluated by retrospectively reviewing medical images and records. Results All patients achieved successful catheter tip positioning without abutment or dysfunction. The median tip position was 15.3 mm distal to the cavoatrial junction (CAJ) on fluoroscopy and 6 mm distal to the CAJ on CT. Catheter tips migrated a median of 10.4 mm cephalically on CT compared to fluoroscopy. Thromboses were detected in the RA and superior vena cava in one patient each. Conclusion Intentional catheter tip positioning in the RA without abutment is a safe and feasible technique with a low incidence of thrombosis and no observed dysfunction.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.05a
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• pp.1107-1110
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• 2005

본 논문은 의료영상진단시스템에서의 의료정보보호를 위한TLS 프로세서의 구현에 관하여 기술하였다. DICOM 3.0 standard의 ‘Part 15. DICOM Security Profile’에서는 TLS와 ISCL 두 가지의 Secure Transport Connection Profile을 정의하고 있고, 인증, 데이터의 무결성 보장, 프리아버시 보호의 기능을 할 수 있도록 몇가지의 알고리즘을 사용할 것을 정의하고 있다. 그 중 TLS Security Profile에는 Triple DES CBC모드와, RSA and SHA를 정의하고 있다. 그리하여 본 논문에서는 세 알고리즘의 개별적인 동작 검증을 마친 후 통합된 TLS Processor를 설계하고 검증하였다. 일반적인 Mux만을 이용한 설계는 임베디드 시스템 적용에 있어서 면적을 많이 차지하는 단점이 나타났다. 따라서 면적을 많이 차지하는 레지스터를 줄이기 위해서 세 알고리즘 블록이 같은 레지스터를 공유하도록 설계하였다. 그리고 임베디드시스템 개발 키트인 IFC-ETK100장비의 FPGA에 회로를 올리고 검증하였다.

• KIPS Transactions on Computer and Communication Systems
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• v.12 no.3
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• pp.119-126
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• 2023

Sarcopenia is not well known enough to be classified as a disease in 2021 in Korea, but it is recognized as a social problem in developed countries that have entered an aging society. The diagnosis of sarcopenia follows the international standard guidelines presented by the European Working Group for Sarcopenia in Older People (EWGSOP) and the d Asian Working Group for Sarcopenia (AWGS). Recently, it is recommended to evaluate muscle function by using physical performance evaluation, walking speed measurement, and standing test in addition to absolute muscle mass as a diagnostic method. As a representative method for measuring muscle mass, the body composition analysis method using DEXA has been formally implemented in clinical practice. In addition, various studies for measuring muscle mass using abdominal images of MRI or CT are being actively conducted. In this paper, we develop an AI image segmentation model based on abdominal images of CT with a relatively short imaging time for the diagnosis of sarcopenia and describe the multicenter validation. We developed an artificial intelligence model using U-Net that can automatically segment muscle, subcutaneous fat, and visceral fat by selecting the L3 region from the CT image. Also, to evaluate the performance of the model, internal verification was performed by calculating the intersection over union (IOU) of the partitioned area, and the results of external verification using data from other hospitals are shown. Based on the verification results, we tried to review and supplement the problems and solutions.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2002.06a
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• pp.89-104
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• 2002

유전체연구사업단은 국내에서 발병 및 사망빈도가 가장 높은 위암과 간암의 퇴치를 목적으로 국가적 특목전략사업으로 연구를 추진하고 있다. 이와 별도로 보건복지부에서는 22개의 중요 질병별 유전체 연구센터를 전국적으로 추진하고 있다. 따라서, 연구가 성공적으로 진행되면 각 연구소에서 독자적으로 개발하여 제공하는 생명정보의 양은 거의 무한에 이를 것이다. 그러나 생명정보는 환자진료에 도움을 주기 위해서는 궁극적으로 임상정보와 함께 유기적으로 통합되어야 한다. 임상정보와의 통합을 위해서는 의료기관의 진료정보와 연구소의 생명정보가 연계되어 엄밀한 임상실험이 추가적으로 실시되어야 한다. 뿐만 아니라 생명정보학의 발전을 위해서는 연구대상의 임상정보가 공유되어야 한다. 유전체정보를 이용하는 생명정보학(Bioinformatics)은 각 국가마다 전략사업으로 간주하여 막대한 투자가 이루어지는 새로운 분야이다. 현재 선진국에서 개발 사용 중인 시스템의 연간 사용료가 고가이므로 국내 도입은 거의 불가능하거나 또는 매우 비효율적이다. 유전체 또는 생명정보의 임상활용 및 생명정보연구를 위한 임상정보 공유를 위해서는 우선 다음의 사항이 개발되어야 한다. 1) 다음과 같은 개별환자의 정보를 각 의료기관에서 제공 받아 저장 활용한다. - 진찰 및 임상소견, 수술기록, 경과기록, 검사결과 (임상병리, 해부병리, 방사선 등), - 영상정보 (X-ray, CT, MRI, 초음파, 전자현미경, 그래픽 등), - 환자개인기록(병력, 과거력, 가족력, 알러지 등), - 예방접종 기록 2) 각 연구소에서 첨단기술을 이용하여 개발되는 생명정보를 임상에 활용하기 위해서는 유전체연구센타와 병원간에 임상정보와 유전체 분석정보의 공유가 필수적으로 발생하게 됨으로, 유전체 정보와 임상정보의 통합은 미래 의료환경에 필수기능이 될 것이다. 3) 각 생명공학 연구소에서 사용하는 첨단 분석 장비와 생명공학 정보시스템의 자동 연계가 필요하다. 현재 국내에는 전국적인 초고속정보망이 가동되어 웹을 기반으로 하는 생명정보의 공유는 기술적으로 문제가 될 수 없으나 임상정보의 유전체연구에 그리고 유전체연구정보의 임상활용은 다양한 문제를 내포하고 있다. 이에 영상을 포함한 환자정보의 유전체연구센터와 병원정보시스템과의 효율적인 연계통합 운영을 위해 국내에서는 초기 도입단계에 있는 국제적인 보건의료정보의 표준인 Health Level 7 (textural information 공유), DICOM (image 및 wave 공유), 관련 ISO표준, WHO의 ICD9/10 (질병분류), LOINC (검사 및 관련용어), SNOMED International (의학용어) 등을 활용하여야 한다.

• Journal of KIISE:Computing Practices and Letters
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• v.13 no.3
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• pp.131-140
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• 2007

A general medical information service in hospitals recently has been rapidly developed in the effective patient management due to the digitalization. In addition, the hospitals make an effort to support the medical information service in ubiquitous environment. A key requirement in ubiquitous environment is the ability to communicate between the image viewer system using the DICOM standard and a server system to support the medical information service. This paper describes a remote networking system based on the mobile terminal with RFID technology for the medical information service. In order to apply the overall configuration, we first implemented the DICOM viewer system, configured the database to store the patient information, and realized the server/client networking system in mobile terminal environment. In particular, this paper showed the capability for the medical image-based communication as well as the text-based communication.

• Journal of radiological science and technology
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• v.37 no.4
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• pp.295-305
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• 2014

This study is to provide accurate information as medical imaging equipment to check for the presence of body disease US equipment. We investigated the status of medical US equipment performance in Daegu and criteria US phantom (ATS-539) for US equipment performance measurements. The results in this study, 1. US phantom measurement results: The test passed rate were 88.6% and the failed rate were 11.4%. 2. The difference between the group of mean and the pass/failed groups were statistically significant. Focal zone and 4 mm functional resolution in the two items that are not present the passing standard. 3. The difference was statistically significant number of years and used equipment and pass the failed equipment (4.13 vs 7.25 years). We investigated the performance status of US equipment used in the clinical area in Daegu. The basis for the two items are not present this proposed passing standard. Equipment performance was associated with the number of years of using US equipment. It is necessary to maintain the best performance of the equipment phantom measurements for performance testing of US equipment.

• Progress in Medical Physics
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• v.22 no.3
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• pp.155-162
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• 2011

The analog image based system consisted of a simulator and medical linear accelerator (LINAC) for radiotherapy was upgraded to digital medical image based system by exchanging the X-ray film with Computed Radiography (CR). With minimum equipments shift and similar treatment process, it was possible that the new digital image system was adapted by the users in short time. The film cassette and the film developer device were substituted with a CR cassette and a CR Reader, where the ViewBox was replaced with a small size PC and a monitor. The viewer software suitable for radiotherapy was developed to maximize the benefit of digital image, and as the result the convenience and the effectiveness was improved. It has two windows to display two different images in the same time and equipped various search capability, contouring, window leveling, image resizing, translation, rotation and registration functions. In order to avoid any discontinuance of the treatment while the transition to digital image, the film and the CR was used together for 1 week, and then the film developer was removed. Since then the CR System has been operated stably for 2 months, and the various requests from users have been reflected to improve the system.

• Sleep Medicine and Psychophysiology
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• v.25 no.2
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• pp.82-91
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• 2018

Objectives: Synchronous electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) has been used to explore sleep stage dependent functional brain networks. Despite a growing number of sleep studies using EEG-fMRI, few studies have conducted network analysis on whole night sleep due to difficulty in data acquisition, artifacts, and sleep management within the MRI scanner. Methods: In order to perform network analysis for whole night sleep, we proposed experimental procedures and data processing techniques for EEG-fMRI. We acquired 6-7 hours of EEG-fMRI data per participant and conducted signal processing to reduce artifacts in both EEG and fMRI. We then generated a functional brain atlas with 68 brain regions using independent component analysis of sleep fMRI data. Using this functional atlas, we constructed sleep level dependent functional brain networks. Results: When we evaluated functional connectivity distribution, sleep showed significantly reduced functional connectivity for the whole brain compared to that during wakefulness. REM sleep showed statistically different connectivity patterns compared to non-REM sleep in sleep-related subcortical brain circuits. Conclusion: This study suggests the feasibility of exploring functional brain networks using sleep EEG-fMRI for whole night sleep via appropriate experimental procedures and signal processing techniques for fMRI and EEG.