• The Korean Journal of Mycology
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• v.25 no.2 s.81
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• pp.133-142
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• 1997

The chemical media composition and culture conditions were optimized for mycelial growth of Phellinus igniarius 26005. The method of solid-state fermentation, cultivation of basidiomycetal strains in various grains, was developed. Media composition for optimal growth of Phellinus igniarius 26005 was made of 7.0% malt extract, 0.3% bacto soytone, and 0.2% yeast extract. The optimum condition for mycelial growth was $28^{\circ}C$ and pH 7.0, respectively. For the mass cultivation of mycelia, the hydrated grains with cold water, were put into the plastic bottle. The mycelial growth rate in the bottled grains was high in the early stage with inoculation of homogenized mycelium. The activity of mycelium was maintained by adding sterilized water in the middle of cultivation. The glucosamine content which determins the mycelial growth rate in solid material was in the order of job's tears>barley>black soybean>wheat>malt soybean>brown rice>sorghum>glutinous rice.

• Journal of dental hygiene science
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• v.13 no.2
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• pp.158-164
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• 2013

The most frequently encountered problems at fixture-implantation sites are lack of adequate bone and proximity to anatomic structures. It is generally accepted that growth factors play an essential role in the healing process and tissue formation, and they have become the focus of grafting materials research. The granules in platelets contain high concentrations of various growth factors. In particular, platelet-rich fibrin (PRF) is a second-generation platelet concentrate that allows the production of fibrin membranes enriched with platelets and growth factors from an anticoagulant-free blood harvest. This study investigated the in vitro effects of PRF on osteoblasts, in terms of the key cellular functions, and especially the effects on two growth factors, the homodimer of platelet-derived growth factor subunit B (BPDGF-BB) and transforming growth factor (TGF)-${\beta}1$, which are associated with wound healing and regeneration (i.e., proliferation and differentiation). The following parameters were investigated: PDGF-BB and TGF-${\beta}1$ levels in PRF, cell viability, alkaline phosphatase (ALP) activity, type 1 collagen synthesis, and the expressions of osteoblast differentiation markers (ALP and runt-related transcription factor 2) and bone matrix proteins (type 1 collagen). The release of autologous growth factors from PRF was maintained for a reasonable period of time, and exerted positive effects on the proliferation and differentiation of osteoblasts. The use of PRF thus appears to be a promising method for enhancing bone healing and remodeling.

• Applied Microscopy
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• v.39 no.2
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• pp.157-165
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• 2009

Here we demonstrate the fine structural characteristics of the spigots on the cribellum and its peculiar sieve-like structure at the aspects of the functional significance. The surface of the cribellum is covered by hundred of tiny spigots which producing numerous cribellate silk fibrils. It has been known that the cribellar silk is considered as a quite different sort of catching silk with dry-adhesive properties. By our fine structural observation using the field emission scanning electron microscopy (FESEM), the titanoecid spiders have a specialized sieve-like plate just in front of the anterior spinnerets. The other types of the silk spigots were identified as follows: ampullate, pyriform and aciniform glands. Two pairs of major ampullate glands send secretory ductules to the anterior spinnerets, and another 1~2 pairs of minor ampullate glands supply the median spinnerets. In addition, the pyriform glands send ductules to the anterior spinnerets, and the aciniform glands feed silk into the median and the posterior spinnerets, respectively. Characteristically, 2 distinct types (A & B types) of the aciniform spigots were identified in this spider, and the spigots of the aciniform B type are always detected at the posterior spinneret, however sexual dimorphism for spigot is unlikely to be exhibited in this species of spider.

• Journal of the Korean Arthroscopy Society
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• v.6 no.2
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• pp.156-160
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• 2002

Purpose : To evaluate the results and usefulness of meniscal repair using meniscal arrows with ACL reconstruction. Material and Methods : Among cases of the simultaneous meniscal arrow fixation and ACL recontruction performed between May, 1997 and September, 2000, 17 cases could be evaluated. The average follow-up were 18.5 months. Twelve cases were medial meniscus, 5 cases, lateral meniscus. All cases were longitudinal tear. Meniscal tear were seen at red-red zone in 13 cases, red-white zone in 5 cases. The results were analyzed by pain, joint line tenderness, locking, McMurray test, the Marshall knee scoring scale and complications. Results : Postoperatively two patients had mild joint line tenderness without pain on joint motion or weight bearing. No patient had locking or positive McMurray test. At last follow-up, 15 cases $(88\%)$ were 'excellent' or 'good' according to the Marshall knee score scale. There were two complications which are soft tissue irritation sign on active knee motion and a femoral chondral injury due to protruded T-shaped head of meniscus arrow. Conclusion : Meniscus arrow can be one of the options in repairing the associated meniscus tear, especially the posterior horn of medial meniscus, during ACL reconstruction. However, surgeons using meniscus arrow should be aware of its potential complications such as pain due to soft tissue irritation and chondral damage of the femoral condyle.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.3
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• pp.531-539
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• 2017

The strut-tie model approach has been recognized as an efficient methodology for the design of all types of concrete members with D-regions, and the approach has been accepted in design codes globally. However, the design of concrete members with the approach requires many iterative numerical structural analyses, numerous graphical calculations, enormous times and efforts, and designer's subjective decisions in terms of the development of appropriate strut-tie model, determination of required areas of struts and ties, and verification of strength conditions of struts and nodal zones. In this study, a computer graphics program, that enables the design of concrete members efficiently and professionally by overcoming the forementioned limitations of the strut-tie model approach, is developed. In the computer graphics program, the numerical programs that are essential in the strut-tie model analysis and design of concrete members including finite element analysis programs for the plane truss and solid problems with all kinds of boundary conditions, a program for automatic determination of effective strengths of struts and nodal zones, and a program for graphical verification of developed strut-tie model's appropriateness by displaying various geometrical shapes of struts and nodal zones, are loaded. Great efficiency and convenience during the application of the strut-tie model approach may be provided by the various graphics environment-based functions of the proposed program.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.58-65
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• 2020

3D Models of offshore plant piping materials designed by 3D CAD systems are provided to the production processes in the form of 2D piping drawings and 2D piping installation drawings. In addition to the standard engineering information, the purchasing, procurement, manufacturing, installation, and inspection of raw materials are managed systematically in an integrated process control system. The existing integrated process management system can help reduce the processing time by managing the flow and progress of resources systematically, but it does not include 3D design model information. Hence, it is difficult to understand complicated pipe structures before installing the pipe. In addition, when design changes or immediate design modifications are required, it is difficult to find related data or exchange information quickly with each other. To solve this problem, an offshore plant-piping process-monitoring system was developed based on a 3D model. The 3D model-based piping monitoring system is based on Visual Studio 2017 C# and UNITY3D so that the piping-process work information can be linked to the 3D CAD model in real time. In addition, the 3D model could check the progress of the pipe installation process, such as block, size, and material, and the progress of functional inspection items, such as cleaning, hydraulic inspection, and pneumatic inspection.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.310-315
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• 2017

Automotive waterproof connectors are highly functional parts that must be air-tight in a complex environment. In the LSR multi-cavity injection molding process for manufacturing waterproof connectors, it is important to maintain a uniform curing temperature between the cavities in order to obtain a quality product. For this purpose, we designed the capacity of the cartridge heater differently for each position, and then linked the heat transfer analysis and optimization module to obtain the optimal cartridge heater capacity. As a result of the optimization analysis, the temperature deviation between cavities was decreased from $13.1^{\circ}C$ to $8.1^{\circ}C$ compared with the case in which constant heater capacity was applied, so that the design criterion could be satisfied within a temperature deviation of $10^{\circ}C$ for uniform curing. This study suggests that this method can be applied efficiently to the design of a large area multi-cavity LSR mold heater.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7331-7339
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• 2014

As the Korean government initiates the Han-style campaign, the efforts and expectations for the modernization and industrialization of Hanok are growing. Accordingly, a major R&D project sponsored by the government is in progress for the development of related technologies, in which the development of a Hanok design support system based on Building Information Modeling(BIM) technology is included as one of the major subjects. However, the development of design tools for Hanok so far has not focused on the windows and doors, which is another major element of Korean traditional architecture. Therefore, this study developed a BIM-based design tool for Hanok windows and doors as an approach to the integrated design of various Hanok elements and their applications to modern buildings. To this end, the characteristics of Hanok windows and doors were analyzed first in terms of the location, opening method, style, components, and the over-all construction. A design tool was then developed with the parametric modeling functions of the $ArchiCAD^{(R)}$system. The applicability and efficiency of the developed tool were verified with design simulations. This is expected to contribute to not only the application of Hanok windows and doors to modern buildings but also to the further development of an integrated Hanok design system.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.2
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• pp.318-323
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• 2013

This study was carried out to investigate the levels of awareness of fermented vegetable beverages according to consumers' gender. The data were obtained through questionnaires completed randomly by 441 respondents and analyzed using the SPSS, t-tests, ANOVA, X-square tests, multiple regression, and logistic regression analyses. Among 441 respondents, 32.9% of male and 30.2% of female ever consumed fermented vegetable beverages. This beverage were consumed as an alternative for water in males (6.3%) and in females (7.9%) which was the most common reason for consumption. As for the most common reason for non-consumption, males (5.9%) and females (6.6%) responded that they did not consume fermented vegetable beverages because people around them have never consumed fermented vegetable beverages. The awareness that fermented vegetable beverages help reduce hunger was higher in females (3.2%) than and in males (2.9%). These results revealed that the awareness of fermented vegetable beverages as hunger alleviators was more prevalent in females than in males which can be used as preliminary data for research on the development of fermented vegetable beverages.

• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.4
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• pp.587-596
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• 2006

Most of oral streptococci express the Antigen I/II (AgI/II) proteins, cell wall anchored adhesions. AgI/II protein binds to salivary agglutinin glycoprotein, a component of tooth pellicle and to ligands in other bacteria. These associations play important roles in bacterial colonization. Recently, it was reported that diverse host molecules also interact with AgI/II protein and that these interactions induce inflammatory responses from host cells. Among mutans streptococci containing -type hemolytic activity, Streptococcus mutans is a causative agent for dental caries. Compared with many other strains of S. mutans, GS-5 strain is unique in that this bacterium expresses truncated secretory AgI/II protein due to the nonsense mutation in the agI/II gene. This indicates that S. mutans GS-5 has a different clinical role and a recent report supported this idea based on the results from clinically isolated S. mutans strains. Previously, we had cloned agI/II gene from S. mutans GS-5 and generated recombinant N-terminal AgI/II protein. In this study, we further produced a hybridoma line expressing anti-AgI/II monoclonal antibodies named as 1C11A. This antibody showed high sensitivity to AgI/II protein in Western blot and ELISA. This new reagent will provide a basis for investigating the mechanisms of AgI/II-related diseases.