• Polymer(Korea)
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• v.37 no.2
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• pp.141-147
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• 2013

Poly(lactide-co-glycolic acid) (PLGA) has been widely used in the drug delivery and tissue engineering applications because of its good mechanical strength and biodegradation profile. However, cell attachment to the scaffold is low compared with that on fibrin although cells can be attached to the polymer surface. In this study, PLGA scaffolds were soaked in cells-fibrin suspension and polymerized with dropping fibrinogen-thrombin solution. Cellular proliferation activity was observed in PLGA/fibrin-seeded costal cartilage cells (CC) on 1, 3, and 7 days using the MTT assay and SEM. The effects of fibrin on the extracellular matrix (ECM) formation were evaluated using CC cell-seeded PLGA/fibrin scaffolds. The PLGA/fibrin scaffolds elicited more production of glycosaminoglycan (GAG) and collagen than the PLGA scaffold. In this study, fibrin incorporated PLGA scaffolds were prepared to evaluate the effects of fibrin on the cell attachment and proliferation in vitro and in vivo. In this result, we confirmed that proliferation of cells in PLGA/fibrin scaffolds were better than in PLGA scaffolds. The PLGA/fibrin scaffolds provide suitable environment for growth and proliferation of costal cartilage cells.

• Korean Journal of Poultry Science
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• v.47 no.1
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• pp.9-19
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• 2020

Avian influenza (AI) viruses are highly contagious viruses that infect many bird species and are zoonotic. Ducks are resistant to the deadly and highly pathogenic avian influenza virus (HPAIV) and remain asymptomatic to the low pathogenic avian influenza virus (LPAIV). In this study, we identified common differentially expressed genes (DEGs) after a reanalysis of previous transcriptomic data for the HPAIV and LPAIV infected duck lung cells. Microarray datasets from a previous study were reanalyzed to identify common target genes from DEGs and their biological functions. A total of 731 and 439 DEGs were identified in HPAIV- and LPAIV-infected duck lung cells, respectively. Of these, 227 genes were common to cells infected with both viruses, in which 193 genes were upregulated and 34 genes were downregulated. Functional annotation of common DEGs revealed that translation related gene ontology (GO) terms were enriched, including ribosome, protein metabolism, and gene expression. REACTOME analyses also identified pathways for protein and RNA metabolism as well as for tissue repair, including collagen biosynthesis and modification, suggesting that AIVs may evade the host defense system by suppressing host translation machinery or may be suppressed before being exported to the cytosol for translation. AIV infection also increased collagen synthesis, showing that tissue lesions by virus infection may be mediated by this pathway. Further studies should focus on these genes to clarify their roles in AIV pathogenesis and their possible use in AIV therapeutics.

• Journal of the Korea Society for Simulation
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• v.23 no.2
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• pp.73-84
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• 2014

Recently, researches on the application of IT technology to various fields including traditional industries are becoming more popular. One challenge in the field of education is to understand the way how technology may support learning, and research on self-directed learning has been accelerated by integrating education and IT technology. The process of self-directed learning in e-learning applications such as Car Maintenance Training is very difficult and complicated. Previous studies on car maintenance training applications provided simple training scenarios with predetermined action sequences. To incorporate self-directed learning in car maintenance training, however, trainees must be able to perform various maintenance operations himself and experience various situations. To provide such functionality, it is necessary to obtain an accurate response for various operations of trainees, but it requires complicated calculations with respect to varieties in the electrical and mechanical processes of a car. In this paper, we develop a logic simulation agent using JESS inference engine in which self-directed learning is achieved by capturing the behavior of trainees and simulating car operations without complicated physical simulations in car maintenance training.

• Food Science and Preservation
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• v.11 no.4
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• pp.448-454
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• 2004

This study was conducted to analyze the cooling and the quality characteristics of milled rice stored in the forced air-blast type using thermo -electric semiconductor and in the still-air type chambers using refrigeration system with refrigerant(R-22). Cooling rates of milled rice in the forced air-blast type and in the still-air type chambers were $0.30\;^{\circ}C/hour$ and $0.21\;^{\circ}C/hour$, respectively. And the temperatures of cooling air and of milled rice at different positions in the forced air-blast type chamber showed severer change than those in the still-air type chamber. During storage of milled rice in the forced air-blast type and still-air type chambers for 14 weeks, there was no significant difference in the quality characteristics, such as b value and fat acidity of milled rice, and overall sensory quality of cooked rice. But the quality characteristics of milled rice stored in room temperature chamber($25^{\circ}C$) as control decreased very rapidly compare to those stored in the cooling chambers. In aspect of fat acidity of milled rice, 6 weeks was the limitation for the safe storage in room temperature.

• Journal of the Korean Geotechnical Society
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• v.15 no.2
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• pp.3-16
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• 1999

The objective of BMP( Barge Mounted Plant) project is to construct plants on mooring floating structures at sea. To analyze the pile behavior under mooring dolphins, generally, axial or lateral behavior of soil-pile system is evaluated by using a nonlinear subgrade reaction method which models the pile as a structural element and the soil as series of nonlinear springs along the depth. As a result, load-displacement curves at pile head can be solved by finite difference method and the equivalent stiffness of bottom boundaries of dolphin structure is evaluated. In this study off-shore site investigation was performed on the marine area of Koje Island and axial and lateral load transfer curves of the ground were modeled with depth. The subgrade reaction analysis was performed for piles under axial or lateral loadings, and the required penetration depth and section of the pile were determined. Subsequently, the spring boundaries under the dolphin structure could be modeled from the calculated load-displacement curve and then the dynamic response of the dolphin structure was analyzed reasonably by considering ground conditions. The analysis considering the stiffness of the soil-pile system has resulted in larger displacement amplitudes than those for rigid foundations. Furthermore, moment distributions of the casing were dependent on the soil-pile system so that deformable foundation induces the larger moment of top section of casing and the smaller moment of pile head.

• Journal of Intelligence and Information Systems
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• v.16 no.4
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• pp.113-130
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• 2010

During the decades, considerable human interventions to comprehend the web information were increased continually. The successful expansion of the web services made it more complex and required more contributions of the users. Many researchers have tried to improve the comprehension ability of computers in supporting an intelligent web service. One reasonable approach is enriching the information with machine understandable semantics. They applied ontology design, intelligent reasoning and other logical representation schemes to design an infrastructure of the semantic web. For the features, the semantic web is considered as an intelligent access to understanding, transforming, storing, retrieving, and processing the information gathered from heterogeneous, distributed web resources. The goal of this study is firstly to explore the problems that restrict the applications of web services and the basic concepts, languages, and tools of the semantic web. Then we highlight some of the researches, solutions, and projects that have attempted to combine the semantic web and business support, and find out the pros and cons of the approaches. Through the study, we were able to know that the semantic web technology is trying to offer a new and higher level of web service to the online users. The services are overcoming the limitations of traditional web technologies/services. In traditional web services, too much human interventions were needed to seek and interpret the information. The semantic web service, however, is based on machine-understandable semantics and knowledge representation. Therefore, most of information processing activities will be executed by computers. The main elements required to develop a semantic web-based business support are business logics, ontologies, ontology languages, intelligent agents, applications, and etc. In using/managing the infrastructure of the semantic web services, software developers, service consumers, and service providers are the main representatives. Some researchers integrated those technologies, languages, tools, mechanisms, and applications into a semantic web services framework. Therefore, future directions of the semantic web-based business support should be start over from the infrastructure.

• Korean Chemical Engineering Research
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• v.45 no.4
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• pp.328-334
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• 2007

Chemical heat pump system of 2-propanol/acetone/hydrogen is most suitable to the recovery of waste heat of power plant. various types of 5 wt% Pt-alumina catalysts were prepared for 2-propanol dehydrogenation using sol-gel method. The characteristics and the dehydrogenation reaction rate of each catalyst were investigated. Pt-alumina xerogel catalyst has excellent reaction rate and good durability in comparison with the existing alumina supported Pt catalysts. Pt-alumina aerogel catalyst had the highest reaction rate in all prepared catalysts, but sufficient aging time was necessary to maintain its reaction rate. A potential advantage of the aerogel catalyst is the fact that the high temperature heat treatment is not required. Without heat treatment or with low temperature heat treatment, the Pt-alumina aerogel catalyst has excellent reaction rate as well as durability and this gives us the economic advantage. Alumina xerogel supported Pt catalyst prepared by incipient wetness method showed good reaction rate, and had good mechanical strength. Blank alumina xerogel prepared by sol-gel method can be used for the support of metal catalysts.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2002.08a
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• pp.13-31
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• 2002

쌀은 중국에서 중요한 식량작물로 제9차 5개년 계획(1966-2000년) 동안 재배면적 31.4백만 ha이며 생산량은 단위 ha당 6,303kg으로 198백만톤에 이르며 이는 재배면적으로는 식량작물의 27.7%, 그리고 생산량으로는 전체식량작물의 40%를 각각 점하고 있다. 이러한 재배면적과 생산량은 각각 세계전체면적과 생산량의 20.7%와 33.7%를 차지하는 많은 량이다. 중국의 남부지역은 전지역의 73.5%가 이모작으로 재배되며 주품종은 Indica이다. 중국의 중부지역은 이모작과 일모작의 재배형태가 2:3으로 공존하고 있으며 양쯔강 이북은 주로 일모작의 형태이다. 중국의 쌀 재배면적은 1960년대 이후 점차 증가하다가 1980년대 후반으로 정체되었다가 최근 90년대 말에 이르러서는 재배면적의 감소가 가속화되고 있으나 단보당 생산량은 꾸준히 증가하고 있다. 2001년 중국의 쌀소비량은 138백만톤으로 이의 85.2%는 식량용으로, 5.8%는 사료용으로, 1.3%는 가공용, 1.5-2.0%는 수출용으로 그리고 1.2%는 종자용으로 소비되었다. WTO체제에 들어서도 중국의 쌀 생산에는 크게 영향을 받지않을 것으로 여겨지는데 그 이유로는 충분한 생산능려과 자급률, 쌀의 낮은(4%) 국제교역비율, 총생산량에 대한 낮은 쿼터비율 등을 들 수 있다. 그러나 WTO체제 가입에 따른 압력 또한 존재하는 것이 사실인데 그것은 낮은 품질, 국제가격보다 높은 국내가격 등을 들 수 있다. 향후 중국 쌀의 발전적 전략들로는 쌀의 안정적 발전을 지속하는 일, 쌀 재배구조 조정과 함께 높은 미질을 가지는 품종육종, 기계화를 비롯한 경작기술의 발달, 쌀과 부산물 가공기술의 개발연구, 특징 기능을 함유하는 유전공학적 기술의 적용, 토지와 도시화 그리고 식량순환에 시스템의 개혁 등 과학기술을 고양하는 일 등을 들 수 있다.TEX>$\times$10cm의 소식일수록 짧아서 재식주수와 경장은 정의상관이 인정되었다. 9 경직경은 30$\times$10cm, 40$\times$10cm의 소식일수록 크고 20$\times$10cm의 밀식일수록 작았다 10. 수량구성요소인 주근장과 수량인 건근중은 30$\times$10cm, 40$\times$10cm의 재식주수가 적을수록 높아서 재식주수와는 부의 상관이 인정되었다. 11 이상과 같은 결과로 보아 경직경이 크고 주근장이 길어서 10a당 건근중이 많은 30$\times$10cm(33주/$m^2$)가 알맞은 재식거리였다.에 대한 인식을 새롭게 하고 농약취급시의 건강장해예방행동을 촉구하는 등의 효과도 높은 것으로 예방의학적인 유용성이 크다고 볼 수 있다. 미침을 알 수 있었다. 대두 단백질로 코팅된 golden delicious는 상온에서60일 동안 보관하였을 경우, 사과표피의 색도 변화를 현저히 지연시킴을 확인하였다. 또한 control과 비교하여 성공적으로 사과에 코팅하였으며, 상온에서 보관하여을 때 사과의 품질을 30일 이상 연장하는 효과를 관찰하였다. 이들 결과로부터 대두단백질 필름이 과일 등의 포장제로서 이용할 가능성을 확인하였다.로 [-wh] 겹의문사는 복수 의미를 지닐 수 없 다. 그러면 단수 의미는 어떻게 생성되는가\ulcorner 본 논문에서는 표면적 형태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.57-62
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• 2006

Busan New Port, under construction aiming for the hub of Northeast Asia and Partly in operation, had damaged up to 48 billion Won due to Typhoon 'maemi' in 2003. The present criteria of domestic harbor design only describes about the critical wave height with respect to the size of vessel for harbor tranquility. The berth operation ratio which represents the annual available berthing days is depending on the efficiency of cargo handling work and this depends on the motion of the moored vessel due to the wave action and the characteristics of cargo gears. The motion of moored vessel might be related not only to the wave height but also to wave period. Furthermore, the berth operation ratio relies on external forces such as currents and winds, including the characteristics of mooring system and the specification of the moored vessel. In this study we only deal with berth operation ratio in normal sea state, considering wave and current by measured data and numerical calculation. Especially we tried to evaluate the berth operation ratio for each berth adopting the variation of dredging and reclamation plan and the change of wave environment during the process of the new port construction. For better understanding and analysis of wave transformation process, we applied the steady state spectral wave model and extended mild-slope wave model to the related site. This study summarizes comparisons of harbor responses predicted by two numerical predictions obtained at Busan New port site. Field and numerical model analysis was conducted for the original port plan and the final corrected plan.

• Journal of KIISE:Software and Applications
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• v.31 no.4
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• pp.447-456
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• 2004

Information extraction is a process of recognizing and fetching particular information fragments from a document. In order to extract information uniformly from many heterogeneous information sources, it is necessary to produce information extraction rules called a wrapper for each source. Previous methods of information extraction can be categorized into manual wrapper generation and automatic wrapper generation. In the manual method, since the wrapper is manually generated by a human expert who analyzes documents and writes rules, the precision of the wrapper is very high whereas it reveals problems in scalability and efficiency In the automatic method, the agent program analyzes a set of example documents and produces a wrapper through learning. Although it is very scalable, this method has difficulty in generating correct rules per se, and also the generated rules are sometimes unreliable. This paper tries to combine both manual and automatic methods by proposing a new method of learning information extraction rules. We adopt the scheme of supervised learning in which a user-interface agent is designed to get information from the user regarding what to extract from a document, and eventually XML-based information extraction rules are generated through learning according to these inputs. The interface agent is used not only to generate new extraction rules but also to modify and extend existing ones to enhance the precision and the recall measures of the extraction system. We have done a series of experiments to test the system, and the results are very promising. We hope that our system can be applied to practical systems such as information-mediator agents.