• Title/Summary/Keyword: 근력약화

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Distal Myopathy with Rimmed Vacuoles Confirmed by Whole Exome Sequencing (Rimmed vacuole을 가진 원위부 근육병증의 전체 엑솜 서열분석을 이용한 유전적 원인 규명)

  • Seo, Seong Don;Park, Hyung Jun;Song, Hyun Seok;Kim, Hye Jin;Park, Jin-Mo;Hong, Young Bin;Chung, Ki Wha;Choi, Byung-Ok
    • Journal of Life Science
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    • v.24 no.3
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    • pp.311-317
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    • 2014
  • Distal myopathy with rimmed vacuoles (DMRV) or hereditary inclusion body myopathy 2 is an autosomal recessive muscular disorder characterized by early adult-onset weakness of distal muscles and rimmed vacuoles in muscle biopsy. Mutations in the UDP-N-acetylglucosamine 2-epimerase/N-ace-tylmannosamine kinase (GNE) gene are associated with the development of DMRV. In this study, whole exome sequencing (WES) revealed compound heterozygous GNE mutations of p.Asp176Val and p.Val572Leu in a patient with distal limb weakness. Three hundred healthy controls did not show these mutations. All other variants found in distal myopathy-relevant genes were polymorphic. These findings confirmed that the patient had DMRV. This work underscores the usefulness of WES in improving the molecular diagnosis of myopathy.

A case study of radial nerve injury associated with humerus shaft fracture (상완골 간부 골절에 동반된 요골신경손상에 대한 치험 1례)

  • Lee, Jae-Eun;Lee, Jung-Min;Oh, Min-Seok
    • Journal of Haehwa Medicine
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    • v.23 no.1
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    • pp.157-166
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    • 2014
  • Objective : The purpose of this study is to report the patient with radial nerve injury associated with humerus shaft fracture, who was improved by Korean medical treatments. Methods : The patient was treated by Jungsongouhyul pharmacopuncture, electrical stimulation therapy, physical therapy, and herbal medicine according to "Locating Yang brightness meridians" theory. Coding result, Numeric rating scale(NRS) and digital grip dynamometer were used to evaluate the wrist drop, numbness of fingers and grip power. Results : The patient showed the first sign of recovery after 6 weeks from onset. After 9 weeks from onset, the patient could perform delicate manual activity. Grip power showed noticeable improvement as well as coding result and NRS. Conclusions : The results suggest that providing Korean medical treatments according to "Locating Yang brightness meridians" theory is a good method for treating radial nerve injury associated with humerus shaft fracture. But further studies are required to concretely prove the effectiveness of this method for treating radial nerve injury associated with humerus fracture.

The Effect of Ankle Joint Muscle Strengthening Training and Static Muscle Stretching Training on Stroke Patients' Plantar Pressure and Gait (발목관절의 근력 강화 훈련과 정적 근육 신장 훈련이 뇌졸중 환자의 족저압 및 보행에 미치는 영향)

  • Lee, Jin-Hwan;Lee, Jae-Hong;Kwon, Won-An;Kim, Jin-Sang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.3
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    • pp.1153-1160
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    • 2012
  • This study was intended to implement ankle joint dorsi flexion training against ankle muscule strength weakening that erodes stroke patients' gait performance to examine the effect of the training on stroke patients' plantar pressure and gait ability. In this study, 36 stroke patients diagnosed with stroke due to cerebral infarction or cerebral hemorrhage were divided to measure 10MWS which are stroke patients' gait variables maximum plantar pressure by area of the sole by collecting data using an F-scan system during gait. Given these results of the study, compared to other training groups, the ankle muscule strength reinforcing training group showed statistically significant increases of maximum plantar pressure in the great toe, the toe and the first metatasal areas too and thus it can be said that this training increases forward thrust during stroke patients' foot end taking off and positively affects stroke patients' ability to perform gait.

Effects of Core Exercise Program on the Low Back Function in Private Guard and Security (경호원들의 코어프로그램 수행과 요추부 기능개선에 관한 연구)

  • Kang, Min-Wan
    • Korean Security Journal
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    • no.21
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    • pp.1-18
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    • 2009
  • Background: This study was to investigate the effects of spinal strengthening exercise and lumbar stabilization exercise(core exercise program) on trunk muscle strength, flexibility and balance, lumbar function. The subjects of this study were the eighteen subjects who was registered in private guard company. The each exercise group of 9 persons were chosen by random controlled trial. Methods: We used instrument BTE, Libra, Ruler Measuring tape to measured trunk muscle strength, flexibility, balance and lumbar function. Results: The result of this study were summarized below; The flexor muscle strength was improve in lumbar stabilization exercise(core exercise) group(p<.05). The extensor muscle strength was improve in lumbar stabilization exercise(core program) group(p<.05). The trunk flexibility was improve in spinal strengthening exercise group and lumbar stabilization exercise group(p<.05). The balance ability was improve in spinal strengthening group and lumbar stabilization exercise group(core program) group(p<.05). Conclusion: With the above results, demonstrated effects of spinal strengthening exercise and lumbar stabilization exercise in each private guard and security in this study.

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A Case of Nonspecific Interstitial Pneumonia Complicated with Spontaneous Pneumomediastinum, Subcutaneous Emphysema and Pneumatosis Interstinalis (비특이성 간질성 폐렴에서 발생한 자발성 종격동기종, 피하기종과 대장기종)

  • Park, Myung Jae
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.2
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    • pp.138-143
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    • 2008
  • Pneumatosis intestinalis or spontaneous pneumomediastinum are rarely associated with nonspecific interstitial pneumonia (NSIP). However, the development of both conditions in the same patient simultaneously has not been reported previously. A 56-year-old man with NSIP developed spontaneous pneumomediastinum accompanied by subcutaneous emphysema and pneumatosis intestinalis after the treatment with intravenous high dose steroid. The development of spontaneous pneumomediastinum, subcutaneous emphysema and pneumatosis intestinalis in this patient was possibly due to the factors such as NSIP, high dose steroid therapy and subclinical dermatomyositis. Treatment with corticosteroid and cyclosporin gradually improved his exacerbated NSIP and pneumomediastinum, subcutaneous emphysema, pneumatosis intestinalis.

Muscle Strength Activity of Herbal Medicine Extracts of Acanthopanax Sieboldianus and Allium Hookeri (오가피와 삼채 등 생약재 추출물의 근력 활성 효과)

  • Hyun Kyoung Kim;Ho Tae Kim;Pil Jae Lee
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.2
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    • pp.555-563
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    • 2024
  • We were selected oriental medicinal herbs known to be effective in strengthening muscles, improving sarcopenia, treating arthritis and osteoporosis. Amino acids have been reported to be associated with the above-mentioned effects. During the manufacturing process of water extracts of ginseng and samchae, the content of arginine, a basic amino acid, was significantly reduced. The decrease was 99.48mg/100ml for steamed red ginseng compared to 114.07mg/100ml for dried white ginseng, and 54.69mg/100ml for steamed samchae compared to 118.90mg/100ml for dried samchae. The extracts of the wild roots of Acanthus apias and the above-ground twigs of Acanthus apias showed significantly higher DPPH and ABTS radical scavenging activities. Meanwhile, DPPH activity was higher in steamed red ginseng and steamed samchae compared to dried white ginseng and dried samche, but ABTS activity increased to 66.88% for steamed red ginseng compared to 41.96% for dried white ginseng, but was 77.48% for dried samchae and 77.52% for steamed samchae.

근골격계 질환 예방을 위한 시스템적 접근과 추진전략

  • 정은교
    • Bulletin of the Korean Institute for Industrial Safety
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    • v.3 no.1
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    • pp.18-24
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    • 2003
  • 최근 산업사회의 급속한 환경변화는 근로자의 상병구조에서도 나타나 작업이 단순반복화 되며 다양한 작업공구를 반복적으로 사용하게 되어 작업속도와 작업량이 많아지고 운동부족으로 인한 근력의 약화 등에 의해서 근골격계질환이 급속히 증가하고 있다. 이로 인한 근로자의 삶의 질은 물론 결근에 의한 노동력 손실, 제품불량 증가, 산재보상비용 지출증가 등으로 성장을 둔화시키고 사회$.$경제적으로 문제의 심각성을 더해주고 있다. 최근 노동부가 발표한 산업재해통계를 보면 2002년도 산업재해 중 업무상질병자는 5,417명으로 전년대비 136명 감소하였으나, 이중 직업성 근골격계질 환자(신체부담작업 및 요통)는 1,827명으로 전년대비 193명(11.8%) 증가한 것으로 나타났고, 그 발생양상이 집단적이라는 특성을 갖고 있다. 이처럼 직업성 근골격계질환의 업무상 질병에서 차지하는 비율이 증가추세에 있고 대부분의 선진국에서도 과거에는 각종 화학물질에 의한 직업병이 상위를 차지해 오다가 근래에는 동 질환이 업무상질병의 상당부분 이상으로 차지하고 있다. 미국의 경우 1998년 한해동안 253,300건(64.2%) 발생하였고 이 가운데 자동차 관련업종이 가장 많은 비율을 점유하고 있다.(중략)

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Design of the Power Assist Controller for the In-Wheel Type Smart Wheelchair (인휠형 스마트 휠체어를 위한 힘 보조 제어기 설계)

  • Kong, Jung-Shik;Baek, Seung-Yub
    • Journal of the Korean Institute of Intelligent Systems
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    • v.21 no.1
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    • pp.80-85
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    • 2011
  • This paper presents the design of the power-assisted controller for the in-wheel type smart wheelchair by using torque estimation that is predicted by relationship between input voltage and output wheel angular velocity. Nowadays, interest of the moving assistant aids is increased according to the increase in population of the elderly and the handicapped person. However some of the moving assistant aids have problems. For example, manual wheelchair has difficulty moving at the slope, because users lack the muscular strength of their arm. In electric wheelchair case, users should be weak by being decreased muscles of upper body. To overcome these problems, power-assisted electric wheelchair are proposed. Most of the power-assisted electric wheelchair have the special rims that can measure the user's power. In here, the rims have to be designed to install the sensors to measure user's power. In this paper, we don't design the rim to measure the man power. To predict the man power, we propose a control algorithm of the in-wheeled electric wheelchair by using torque estimation from the wheel. First, we measure the wheel velocity and voltage at the in-wheel electric wheelchair. And then we extract driving will forces by using proposed mathematical model. Also they are applied at the controller as the control input, we verify to be able to control in-wheel type smart wheelchair by using simulation.

Medial Retracted Large Rotator Cuff Tears (내측으로 퇴축된 대범위 회전근 개 파열)

  • Ko, Sang-Hun;Cha, Jae-Ryong;Kim, Tae-Won
    • Journal of the Korean Arthroscopy Society
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    • v.13 no.3
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    • pp.212-219
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    • 2009
  • Medially retracted large-sized rotator cuff tears includes large-sized tears, massive tears and irreparable tears. Generally arthroscopic repair or open repair of rotator cuff tears is used in reparable tears. However, arthroscopic repair requires long period practice and endurance. In irreparable tears, arthroscopic debridement, partial repair, latissimus dorsi transfer and retrograde arthroplasty can be the option. Arthoscopic debridement gives temporal relief who experienced improvement in pain and increase in range of motion after subacromial local anesthetic injection. Also arthroscopic partial repair gives good results in irreparable cases, especially in suprascapular nerve traction neurapraxia. Tendon transfer can be used in mild to moderate muscle weakness in shoulder abduction for long term treatment. Pectoralis major transfer can be used in anterosupeior tears and latissimus dorsi transfer can be used in posterosuperior tears. Reverse shoulder prosthesis is used in extreamly weakened shoulder pseudoparalysis. The authors discussed the method of arthroscopic repair in irreparable tears. The debridement, partial repair, and tendon transfer could be used in medially retracted large-sized rotator cuff tears.

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Changes of Functional Performance Ability in Stroke Patients by Exercise Types I : Analysis of Lower Extremity Muscle Activity during Walking (운동유형별 뇌졸중 환자의 기능적 수행능력 변화 I : 보행시 하지근육 활성도 분석)

  • Park, Sung-Hyun;Kim, Jung-Tae
    • Korean Journal of Applied Biomechanics
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    • v.18 no.1
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    • pp.63-72
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    • 2008
  • The purpose of this study was to compare and analyze the effects of exercise types on lower extremity muscle activity in stroke patients. For the purpose, the subjects of this study were classified into three groups such as therapeutic exercise group(n=7), elastic band group(n=7), and stretch reflex group(n=7). The three exercise programs were 5 times a week for 8 weeks. The stretch reflex group revealed higher in iliopsoas and biceps femoris %MVIC than the therapeutic exercise group and elastic band group, whereas elastic band group revealed lower in tibialis anterior %MVIC than therapeutic exercise group in the primary single-limb support. The stretch reflex group revealed higher in iliopsoas %MVIC than the therapeutic exercise group and elastic band group, whereas stretch reflex group revealed lower in medial gastrocnemius %MVIC than therapeutic exercise group in the secondary double support phase.