• The Korean Journal of Pharmacology
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• v.20 no.2
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• pp.23-34
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• 1984

To investigate diurnal variations of opiate receptor binding and its modification by experimental condition or treatment of various centrally-acting drugs, the amount of maximum $^3H-morphine$ binding in rat midbrain homogenates was measured at 4 hour intervals for 24 hours. Animals were conditioned under the controlled L : D, 12 : 12 cycle or D: D, 12 : 12 cycle, for 3 weeks and treated with 0.5 ml of physiological saline or drugs for 2 weeks. A highly significant diurnal rhythm with peak at 22 hour of early dark phase with an amplitude$(0.68{\pm}0.06\;pmole/mg\;protein)$ of +51.1% and nadir $(0.33{\pm}0.03\;mole/mg\;prtein)$ at 18 hour of late light phase with an amplitude of -26.6% was found in control group. 24 tour mean of $^3H-morphine$ binding was $0.45{\pm}0.03\;pmole/mg$ protein respectively. Constant dark adaptation or treatment of reserpine, pargyline, imipramine, amphetamine and chlorpromazine modified the diurnal rhythm in the time of peak and nadir binding shape, phase, amplitude of the diurnal curve and 24 hour mean of $^3H-morphine$ binding. However, Kd values were not changed in all experimental groups : Statistical analysis at times of least and great binding indicates that the differences in $^3H-morphine$ binding were due to changes not in the affinity, but in the number of binding sites. The results are interpreted with regard to the diurnal rhythm of opiate receptor finding. The modes of action of psychoactive drugs are closely related to postulated changes of receptor sensitivity in neuropharmacological aspects.

• The Korean Journal of Nuclear Medicine
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• v.35 no.2
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• pp.83-88
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• 2001

Purpose: The purpose of this study was to ascertain whether radiation adaptive response could be induced by high dose I-131 therapy in patients with differentiated thyroid cancer. Materials and Methods: Lymphocytes from 21 patients (7 males, 14 females, mean age $55{\pm}12$ years) were collected before and after administration of 5,550 MBq (150 mCi) I-131. They were exposed to a challenge dose of 1 Gy gamma rays using a Cs-137 cell irradiator. The number of ring-form (R) and dicentric (D) chromosomes was counted under the light microscope, and used to calculate the frequency of chromosomal aberration. Ydr, which was defined as the sum of R and D divided by the total number of counted lymphocytes. Results: Ydr in patients before I-131 therapy ($0.09{\pm}0.01$) was not different from that of controls ($0.08{\pm}0.01$). Ydr was significantly increased to $0.13{\pm}0.02$ (p<0.0001) after I-131 therapy. Increase of Ydr after the challenge irradiation of 1 Gy was significantly lower in patients after I-131 therapy than before I-131 therapy ($0.17{\pm}0.03\;vs\;0.21{\pm}0.02$, p<0.0001). Cycloheximide (CHM), an inhibitor of protein synthesis, abolished this effect. Ydr after CHM ($0.20{\pm}0.01$) was significantly higher than Ydr after I-131 therapy ($0.17{\pm}0.03$, p<0.0001), but was not different from Ydr before I-131 therapy ($0.21{\pm}0.02$).Conclusion: High dose I-131 therapy induces an adaptive response in peripheral lymphocytes of patients with well-differentiated thyroid cancer, which is associated with protein synthesis.

• The Journal of the Korea Contents Association
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• v.19 no.8
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• pp.240-251
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• 2019

This study was conducted to analyze the mediating effect of grit and self-leadership on the relationship between military life adaptation and college life adaptation among male college students. The subjects of this study were 233 male college students who returned to college after military duty and the average age was 25(SD=1.7). The main results of the study were as follows: First, significant positive relationships were seen between military life adaptation, grit, self-leadership, and college life adaptation. Second, military life adaptation had a significant positive impact on grit, self-leadership, and college life adaptation. Third, grit had a significant mediating effect on the relationship between military life adaptation and college life adaptation. Fourth, self-leadership had a significant mediating effect on the relationship between military life adaptation and college life adaptation. This study showed that military life adaptation improved the grit and self-leadership of college students and that this personal growth had a significant effect on college life adaptation after returning from military duty. Based on these results, the relationship between military life and college life was discussed.

• Korean Journal of Plant Resources
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• v.29 no.1
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• pp.90-109
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• 2016

This study aims to investigate the flora of Mt. Cheonma (Namyangju-si, Gyeonggi-do, Korea), including Korean endemic, rare and endangered plants. To support the biodiversity and usefulness of this investigation, we checked the red list plants, floristic regional indicator plants, climate change adaptation target plants and naturalized plants, and compared composition of plant species in Mt. Cheonma with nearby mountains. Totally, we performed 22 field investigations from April 2012 to October 2014. The number of vascular plants in this region is 433 taxa and comprised of 94 families, 266 genera, 378 species, 2 subspecies, 46 varieties, and 7 forms. Among them, there are 13 endemic plants designated by Korean Forest Service, whereas only 10 taxa are endemic species by Korean Ministry of Environment (KME). According to the IUCN criteria, there are 12 rare and endangered plants composed of 9 Least Concerned (LC), 2 Vulnerable species (VU), and one Endangered species (EN) found by Korea National Arboretum (KNA). Meanwhile, 8 taxa including 7 Least Concerned (LC) were found in Red List of KME. The floristic regional indicator plants designated by KME were 49 taxa. In addition, there are 14 taxa in The Adaptable to Climate Change Plant List designated by KNA, while only 19 taxa are naturalized plants. Generally, there are 190 common taxa in Gwangju Mountains area, and only 51 taxa are distributed in Mt. Cheonma.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.19 no.2
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• pp.211-224
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• 1994

In this paper, a multi-level adaptive intraframe method has been proposed to separate the luminance and chominance components in NTSC composite signal. The control signals are generated by detecting the vertical correlation and transition in the horizontal and diagonal directions. The chrominance component is adaptively processed through vertical and horizontal filters according to the control signals and the luminance component is processed by subtracting the chrominance component from the composite video signal. The several filters have been used at the sampling rate of four times the color subcarrier frequency and computer simulation and SVP(Serial Video Processing) system have been introduced to compare the performance of the conventional methods and that of proposed one.

• The Journal of the Korea Contents Association
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• v.17 no.3
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• pp.633-642
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• 2017

The purpose of this study was to examine the effectiveness that group counselling by transactional analysis influence on personal competence and communication for maladaptive soldier. 8 participants were assigned to an experimental group and pre and post test was performed. Experimental group were given group counselling program by Transactional Analysis(TA) sessions during 4day, which one session offered for 240 minutes' 8 hour a day. To verify the effectiveness of the group counselling Wilcoxon Matched-Pairs Signed-Ranks Test was performed. The result revealed that group counselling by transactional analysis positively influence on personal competence(self-efficacy, positive character) for maladaptive soldier. This study has a meaning and great achievements to present the possibility of using this program in practical and clinical field, which significant improvement in personal competence, self-efficacy, positive character.

• The Korean Journal of Nuclear Medicine
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• v.33 no.2
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• pp.172-177
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• 1999

Purpose: The purpose of this study was to ascertain whether radiation adaptive response could be induced by Tc-99m-methylene diphosphonate (Tc-99m-MDP) in peripheral lymphocytes of patients undergoing bone scintigraphy. Materials and Methods: Lymphocytes from 22 patients (6 males, 16 females, mean age $50{\pm}14$ years) were collected before and after bone scintigraphy using 740 MBq Tc-99m-MDP Lymphocytes from 10 controls (6 males, 4 females, mean age $43{\pm}7$ years) were also collected. They were exposed to challenge dose of 2 Gy gamma rays using a cell irradiator. Number of ring-form and dicentric chromosomes per 600 cells (chromosomal aberrations) was counted under the light microscope. Results: Chromosomal aberrations in patients before bone scintigraphy ($385.1{\pm}30.5$) was not different from that of controls ($367.8{\pm}36.6$). However, chromosomal aberrations in patients after bone scintigraphy was significantly decreased to $192.6{\pm}22.1$ (p=0.0001). Conclusion: Low dose gamma-irradiation by Tc-99m-MDP used for bone scintigraphy induces a cytogenetic adaptive response in peripheral lymphocytes.

• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.171-179
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• 2023

Due to man-made climate change, global abnormal weather phenomena have occurred, increasing disasters. Major developed countries(military) are preparing for disasters caused by extreme weather appearances. However, currently, disaster prevention plans and facilities have been implemented based on the frequency and intensity method based on statistical data, it is not enough to prepare for disasters caused by frequent extreme weather based on probability basis. The U.S. and British forces have been the fastest to take research and policy approaches related to climate change and the threat of disaster change, and are considering both climate change mitigation and adaptation. The South Korean military regards the perception of disasters to be storm and flood damage, and there is a lack of discussion on extreme weather and disasters due to climate change. In this study, the process of establishing disaster management systems in developed countries(the United States and the United Kingdom) was examined, and the response policies of each country(military) were analyzed using literature analysis techniques. In order to maintain tight security, our military should establish a response policy focusing on sustainability and resilience, and the following three policy approaches are needed. First, it is necessary to analyze the future operational environment of the Korean Peninsula in preparation for the environment that will change due to climate change. Second, it is necessary to discuss climate change 'adaptation policy' for sustainability. Third, it is necessary to prepare for future disasters that may occur due to climate change.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2009.05a
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• pp.215-216
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• 2009

본 연구는 꾸준한 신체활동이 고혈압을 강하시키는데 어떠한 효과가 있는지를 확인하는데 그 목적이 있다. 실험대상은 연령과 성별이 같은 SHR로 실험군과 통제군으로 무작위샘플로 분류하였다. 실험실적응 및 운동적응 기간을 거친 후 운동기간별 혈압의 변화를 관찰하였다. 통계분석은 SPSS 10.0을 사용하였다. 실험결과 집단 간 혈압의 차이가 있었다(p<.05). 실험집단간, 집단내 기간별 상호작용은 유의하게 나타났다(p<.05). 결론적으로 주지적인 신체활동은 SHR의 혈압을 감소시키는 효과가 있다.

• Journal of KIISE:Computer Systems and Theory
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• v.32 no.8
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• pp.399-410
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• 2005

This paper Proposes a novel adaptive genetic algorithm (GA) extrapolated by an ant colony optimization. We first prove that the algorithm converges to the unique global optimal solution with probability arbitrarily close to one and then, by experimental studies, show that the algorithm converges faster to the optimal solution than GA with elitism and the population average fitness value also converges to the optimal fitness value. We further discuss controlling the tradeoff of exploration and exploitation by a parameter associated with the proposed algorithm.