• Journal of Marine Life Science
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• v.7 no.1
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• pp.37-44
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• 2022

This study was performed to obtain information on the sex ratio, size at sexual group maturity, and main spawning period of Glyptocephalus stelleri. The sex ratio (female: male) was 1:0.54 (n=189:103, 64.7% female), and the frequency of females in the population tended to increase with total length. The oocyte development pattern was group synchronous development, in which oocyte groups at different stages were identified within the same ovary. The total length at 50% sexual group maturity was analyzed using a logistic regression model, and was determined to be 28.51 (female) and 30.49 cm (male). The gonadosomatic index (GSI) displayed the highest values in April (female) and March (male), and the main spawning period being in April to May.

• Journal of Practical Agriculture & Fisheries Research
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• v.20 no.2
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• pp.117-123
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• 2018

The purpose of this report is to describe the diagnosed case of a large colonic impaction in an adult donkey. An adult female donkey (Equus africanus asinus; 6-years-old) was admitted to the Equine Hospital of Jeju Race Park with signs of anorexia, which had started 1 day previously. Clinical examination revealed: weak gut sounds, dehydration, and severe abdominal distension, but normal respiratory and heart rates and no signs of pain. Transrectal palpation identified an impaction in the colon. The patient was treated with nasogastric siphonage, fluid therapy, and nonsteroidal anti-inflammatory drugs. Over the course of a day, her condition worsened; she started trembling, could not stand, and 2 hours later she died. Upon necropsy, a vast amount of ingesta was found in the large colon, particularly in the left ventral colon. The cecum and small colon were normal. Eleven days prior to presentation, the stable management and diet of the donkey had changed. We suspect that the change of feed, reduced water consumption, and lack of exercise precipitated the illness. However, the exact cause of the sudden death of the donkey requires further investigation.

• Korean Journal of Heritage: History & Science
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• v.51 no.2
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• pp.78-91
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• 2018

Sangjogam, located in Goseong, Gyeongsangnam-do, was designated as Natural Monument #411, because of its diverse geological heritage, such as fossils, ripple marks, dykes, and columnar joints. In the area, Byeongpungbawi, with its beautiful columnar joints vertical to the bedding plane of the underlying sedimentary rocks and spectacular coastal view, was named after its overall shape reminiscent of a huge folding screen. The purpose of this study was to investigate the formation process of the columnar joints using the anisotropy of magnetic susceptibility (AMS) method. AMS measurements showed that the k1 and k3 values representative of directions of the long and short axes of a magnetic particle at each point strongly clustered, and the oblate magnetic foliation structure in Byeongpungbawi developed during sill-type intrusion rather than lava flow. In summary, Byeongpungbawi was produced by sill-type intrusion along the bedding plane of the underlying sedimentary layer, and the subsequent formation of columnar joints was accompanied by the cooling and contraction of intruding rhyolite magma. This study potentially provides a basic research tool in understanding the formation mechanism of columnar joints which are widely distributed in southern Korea.

• Journal of the Korean Society of Radiology
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• v.82 no.4
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• pp.903-913
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• 2021

Purpose To identify the imaging features indicative of sarcoid-like reactions in patients with intrathoracic lymphadenopathy after complete remission of malignancies. Materials and Methods This study enrolled five patients with histopathologically confirmed sarcoid-like reactions that developed after cancer remission. The clinical features and findings of CT and ¹⁸F-fluorodeoxyglucose (FDG) PET/CT were assessed. Results The underlying malignancies included breast, nasopharyngeal, colon, and endometrial cancer and lymphoma. The time intervals between complete remission of malignancy and the diagnosis of sarcoid-like reaction ranged from 6 to 78 months. CT findings of sarcoid-like reaction included bilateral hilar and mediastinal lymphadenopathies (n = 5), pulmonary nodules (1-15 mm) with peribronchovascular, fissural, or subpleural distribution, and interlobular interstitial thickening in the lungs (n = 4). ¹⁸F-FDG PET/CT revealed hypermetabolic uptake in the mediastinal and hilar lymph nodes and both lungs in the absence of extrathoracic uptake (n = 3). The sarcoid-like reactions resolved in all patients after corticosteroid treatment. Conclusion In patients with complete remission of malignancies, newly developed bilateral hilar and mediastinal lymphadenopathies with or without pulmonary nodules of perilymphatic distribution, in the absence of recurrence at the primary tumor site and extrathoracic metastasis, may suggest a sarcoid-like reaction. Such cases warrant histologic evaluation of the lymph nodes to prevent unnecessary systemic chemotherapy.

• Journal of Life Science
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• v.33 no.9
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• pp.703-712
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• 2023

Angiogenesis, the formation of blood vessels from pre-existing vessels, is a multistep process regulated by modulators of angiogenesis. It is essential for various physiological processes, such as embryonic development, chronic inflammation, and wound repair. Dysregulation of angiogenesis causes many diseases, such as cancer, autoimmune diseases, rheumatoid arthritis, cardiovascular disease, and delayed wound healing. However, the number of effective anti-angiogenic drugs is limited. Recent research has focused on identifying potential drug candidates from natural sources. For example, marine natural products have been shown to have anti-cancer, anti-oxidant, anti-inflammatory, antiviral, and wound-healing effects. Thus, this study aimed to describe the angiogenesis inhibitory effect of Hizikia fusiforms (brown algae) extract. The hexane extract of H. fusiformis has shown inhibitory effects on in vitro angiogenesis assays, such as cell migration, invasion, and tube formation in human umbilical vein endothelial cells (HUVECs). The hexane extract of H. fusiformis (HFH) inhibited in vivo angiogenesis in a mouse Matrigel gel plug assay. In addition, the protein expression of vascular endothelial growth factor (VEGF), mitogen-activated protein kinase (MAPK)/extracellular signal kinase, and AKT serine/threonine kinase 1 decreased following treatment with H. fusiformis extracts. Our results demonstrated that the hexane extract of H. fusiformis (HFH) inhibits angiogenesis in vitro and in vivo.

• Journal of Life Science
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• v.34 no.2
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• pp.122-127
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• 2024

This study investigated the reproductive ecology and spawning of Hoplobrotula armata on the coast of Jejudo Island. Samples were collected from February to December 2019 and February to December 2020, with a total of 2,634 samples. The results of the investigation showed that total length (TL) ranged from 22.0 cm to 68.8 cm, and the body weight (BW) ranged from 66.5 g to 3,553.9 g. According to the development process of gonads and the gonadosomatic index (GSI), the spawning period of H. armata was from July to October. The relationship between TL and BW was BW = 0.0024TL^3.3278 in females and BW = 0.0035TL^3.2162 in males. The sex ratios of surveyed female to male H. armata was 1:0.71, with more females. At 50%, 75%, and 97.5%, the group maturities of H. armata were as follows: Females, 39.9 cm, 42.7 cm, and 49.4 cm; males, 37.6 cm, 40.4 cm, and 46.9 cm, respectively. According to monthly GSI and gametocyte (ovarian, testis) development stage observations of H. armata on the coast of Jejudo Island, they spawn once a year and are presumed to be summer spawners.

• Journal of agricultural medicine and community health
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• v.30 no.3
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• pp.293-303
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• 2005

Objectives: Yearly, annual report of cancer patients in Korea is released by National Cancer Center. But, this report is focused in all of the patients in nation. So, there is needed to modify and analyze this report to be used properly for local resident. In Ulleung island, local county and Ulleung medical center don't have cancer occurrence data of local resident until now. The aim of this analysis is to know characteristics and data of cancer patients occurrence in Ulleung island for 10 years. Methods: We are offered data of cancer patients occurrence in Ulleung island for 10 years from National Cancer Center. This data was composed of sex, address (only town level), diagnosed date, diagnosis. So, we analyze this data and compare to Korea data for same duration. Results: There were 268 patients for 10 years (1993-2002). Man were 175 about 65% and women were 93 about 35%. There were 163 in Ulleungeup about 60%, 39 in Seomyun about 14.5% and 48 in Bukmyun about 18%. There were 19 patients in unknown residence. After 1998, above 30 patients were occurred, but before 1998, below 27 patients were occurred. Diagnosed date was concentrated in June, 33 patients were occurred about 12%, but least occurred month was December. Most occurred age were from 60 to 69, there were 80 patients about 30%. Most occurred cancer was gastric cancer, there were 54 patients about 20%. Hepatic cancer was second and third was lung cancer. In man, most occurred cancers were gastric cancer and hepatic cancer, both was 38 patients. In woman, gastric cancer and uterine cervix cancer were occurred mostly. After 2001, in Korea most occurred female cancer was breast, but in Ulleung island, most occurred cancer was stomach. Conclusions: Researcher should demand and analyze cancer data from National Cancer Center that cancer management project in local county and public health education of cancer could focus on local resident because annually released cancer data from National Cancer Center focus on a nation. In Ulleung island, cancer incidence was more than incidence in Korea and breast cancer was occurred less than in Korea. So, more study should be needed to confirm why more cancer were occurred than Korea and breast cancer was less occurred.

• Journal of Practical Agriculture & Fisheries Research
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• v.4 no.1
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• pp.89-109
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• 2002

필수 미량원소인 셀레늄은 인간의 건강에 기본적으로 중요한 역할을 하는 물질이다. 항산화 관여 효소의 작용과 구조역할을 담당하는 셀레늄이 함유된 단백질(selenoproteins)은 항산화 기능이 있을 뿐만 아니라, 갑상선호르몬의 활성화에 관여하는 것으로 밝혀졌다. 또한, 셀레늄은 정상적인 면역체계의 유지에 필요하며, HIV(human immunodeficiency virus)가 진행되어 AIDS로 발전되는 것을 억제하는 작용이 있다는 사실도 밝혀지고 있으며, 정자의 생성과 운동성에 관계하기도 한다. 우울증 환자가 셀레늄을 섭취하게 되면 효과가 있으며, 셀레늄이 순환계질환의 발생을 억제하는 것으로 알려지고 있다. 특히 최근에는 셀레늄의 섭취가 암발생을 예방할 수 있다는 역학조사결과를 토대로, 대규모 셀레늄 임상실험이 다국적 연구의 형태로 2개의 프로젝트(PRECISE, SELECT)가 수행 중이다. 한편, 셀레늄의 항암효과에 대한 세포수준에서의 연구가 활발하게 이루어지고 있으며, 어느 정도 가시적인 결과를 보이고 있다. 따라서, 셀레늄에 대한 재평가가 우리 나라에서도 이루어져야 한다. 그러기 위해서는 지역별로 셀레늄의 정확한 섭취량조차도 파악되어 있지 않을 뿐만 아니라 일일권장량 값조차 정확하지 않은 현실을 볼 때, 셀레늄의 기본적 연구에 대한 관심을 가져야 할 때라고 판단된다.

• Korean Journal of Social Welfare
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• v.61 no.2
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• pp.325-348
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• 2009

This study intends to investigate the main and mediating effects which caregiving appraisal and positive reappraisal exert on quality of life (QOL) of primary family caregivers of cancer patient considering the relationship with social support. The processes of this study areas follows. First, the variables which research model were chosen on the basis of stress-appraisal-coping theory through reviews of the previous studies. Second, a survey was conducted upon 295 primary caregiver of patient with cancer at National Cancer Center. Collected data were analyzed by SPSS 12.0 and SEM (Structural Equation Modeling) method using AMOS 5.0. The summary of the result is as follows. First, the entire model including measurement and structural model shows sufficient fit index of CFI(.951), TLI(.940) and RMSEA(.062). Second, the results of analysis of direct effects among variables are as follows. The 'Social support' has statistically significant direct effect on the 'feeling of burden' and 'growth'. The 'feeling of burden' has statistically significant direct effect on the 'growth' and 'QOL-mental and physical'. The 'growth' has statistically significant direct effect on the 'QOL-mental'. Third, the results of analysis of mediating effects of the 'social support and QOL' and 'feeling of burden and QOL' are as follows. The effects of 'social support' on 'QOL-mental' are significantly mediated by the 'feeling of burden' and 'growth'. The effects of 'social support' on 'QOL-physical' are significantly mediated by the 'feeling of burden'. The effects of 'feeling of burden' on 'QOL-mental' are significantly mediated by 'growth'. Through this research, these implications in social work study and practice are found: (1) this study extended the scope of study in the caregiver's health area from negative sides into positive ones by using growth variables as positive reappraisalof caregiving in research model, which has not been tried on the Korean family caregivers of the cancer patient. (2) The effects of positive reappraisal on QOL-mental can provide a foundational necessity for social workers to help family caregivers find positive meaning in their caregiving experience. This approach of social work practice will improve QOL of family caregivers. (3) This study present a framework including social support, negative appraisal, positive reappraisal, and QOL variables available to social work practice and explaining affective relationships among these variables in various aspects.

• Korean Journal of Heritage: History & Science
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• v.43 no.3
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• pp.122-143
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• 2010

The Shilla Stone Monument in Jungseongri was found during the road-construction in Pohang. It has approximately two hundreds of letters inscribed on the surface of one side, and it is estimated to be older than Shilla Stone Monument in Naengsuri which had been known for the oldest stele in Shilla Period. This monument is made of fine to medium-grained biotite granite, while the Shilla Stone Monument in Naengsuri is made of fine-grained granodioritic porphyry bearing feldspar and amphibole phenocrysts. Both rock types of the monuments are interpreted to be cognate with biotite granite in Shinkwangmyeon, and with granodioritic porphyry in Gigyemyeon. They are characterized by xenolith and miarolitic cavity. Damage aspects in both monuments are discoloring, cracking and breaking. These damages do not cause structural instability of the monuments, but attenuate aesthetic value. Black and brown discoloring contaminants on the surface of the Jungseongri Monument contain a high amount of manganese and iron. As a result of ultrasonic test, both monuments were evaluated to be medium-weathered (MW), although the velocity of the Shilla Monument in Jungseongri was slightly lower than the Shilla Monument in Naengsuri. This is because the Monument in Juengseongri had been exposed to outdoor environment for long time until the discovery. It is necessary for Shilla Monuments to be protected by appropriately environmental control and management.