• Title/Summary/Keyword: 구성 수준

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Is Genotypic Resistance-guide Eradication Therapy Effective for Patients with Refractory Helicobacter pylori Infection? (불응성 Helicobacter pylori 감염 환자들에게 유전자형 내성을 기반한 제균 치료는 유용한가?)

  • Kim, Sung Eun
    • The Korean journal of helicobacter and upper gastrointestinal research
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    • v.18 no.4
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    • pp.277-279
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    • 2018
  • 전 세계적으로 Helicobacter pylori의 항생제 내성률은 지속적으로 증가하고 있으며, 기존의 제균 치료에 실패한 H. pylori 감염 환자들에 대한 효과적인 구제요법(rescue therapy)의 필요성 역시 증가하고 있다. 이 연구는 두 개 기관, 공개, 평행 그룹, 무작위 배정 연구로서 불응성 H. pylori 감염 환자들의 구제요법으로 유전자형 내성을 기반한 치료(genotype resistance-guided therapy)와 경험적 치료(empirical therapy) 중 어느 것이 보다 효과적인지를 비교하고자 하였다. 2012년 10월부터 2017년 9월까지 20세 이상의 불응성 H. pylori 감염 환자들을 대상으로 하였으며, 불응성 H. pylori 감염은 과거 두 종류 이상의 H. pylori 제균 치료를 받았음에도 불구하고 H. pylori 제균에 실패한 환자들로 정의하였다. 이들에게서 한 군은 14일간의 유전자형 내성을 기반한 순차 치료(n=21 in trial 1, n=205 in trial 2)를, 다른 한 군은 환자들의 과거 제균 치료 종류를 감안한 14일간의 경험적 순차 치료(n=20 in trial 1, n=205 in trial 2)를 시행하였다. 순차 치료법은 첫 7일은 esomeprazole 40 mg과 amoxicillin 1 g을 하루 두 번 복용한 다음, 나머지 7일은 esomeprazole 40 mg과 metronidazole 500 mg, 그리고 1) levofloxacin 250 mg 또는 2) clarithromycin 500 mg 또는 3) tetracycline 500 mg을 하루 두 번 복용하는 것으로 구성하였다. 23S ribosomal RNA (rRNA)나 gyrase A에 대한 내성 관련 돌연변이 여부는 direct sequencing을 통한 중합효소연쇄반응(polymerase chain reaction, PCR) 검사를 이용하였고, 제균 성공 여부는 요소호기검사를 통해 확인하였다. 일차 결과 지표는 치료 방법에 따른 제균율로 정하였다. Trial 1에서는 tetracycline 대신 doxycycline 100 mg을 사용하였는데, 제균 성공률이 유전자형 내성을 기반한 치료군에서는 17명(81%), 경험적 치료군에서는 12명(60%)으로 나타났다(P=0.181). 하지만, 다른 순차 치료군들과 비교하였을 때, doxycycline을 포함한 순차 치료군의 제균율이 현저히 낮은 것으로 나타나서(15/26, 57.7%) doxycycline을 포함한 순차 치료법은 종결하기로 하고, trial 2부터는 doxycycline 대신 tetracycline으로 교체하여 연구를 지속하였다. Trial 2의 intention-to-treat (ITT) 분석 결과, 유전자형 내성을 기반한 치료군에서는 160/205명(78%), 경험적 치료군에서는 148/205명(72.2%)으로 두 그룹 간의 통계적인 제균율의 차이는 보여주지 못하였다(P=0.170). 부작용 및 환자 순응도에서도 양 군 간의 의미 있는 차이는 없었다. 따라서, 두 종류 이상 H. pylori 제균 치료에 실패한 환자들이라고 할지라도 기존의 제균 치료력을 바탕으로 적절한 경험적 치료를 시행하는 것은 유전자형 내성을 기반한 치료 정도의 효과는 있으며 접근성, 비용, 환자들의 선호도 등의 여러 가지 부가적인 사항들을 고려할 때, 제균 치료력을 고려한 경험적 치료는 간단한 수준의 유전자형 내성을 기반한 치료의 대안으로 받아들여질 수 있을 것으로 제안하였다.

Exploring the Direction of School System Reorganization of Meister High School and Analyzing the Perceptions of Participants (마이스터고 학제 개편 방향 탐색 및 관계자 인식 분석)

  • Kim, Seoung-Nam
    • Journal of vocational education research
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    • v.37 no.5
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    • pp.1-23
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    • 2018
  • The purpose of this study was to explore the direction of school system reorganization in order to strengthen the educational competitiveness of Meister high school. Specifically, the first one was to review prior research related to the school system reorganization of vocational education at the secondary level, and to propose school system reorganization plans of Meister high school. And second one was to analyze the perceptions of related parties about this reorganization plans and to derive important implications. The results of this study were as follows. First, based on the results of the analysis of precedent research, school system reorganization plans of Meister high school was composed of (1) introduction of credit system, (2) introduction of 3-semester system, and (3) expansion of school year. Second, as a result of the questionnaire survey conducted by 138 Meister high school teachers and 185 Meister high school graduates, both group seemed to agree on the necessity of school system reorganization of Meister high school. In addition, the necessity of introducing the proposed reorganization plans was more than a certain level, but the applicability was recognized as somewhat lower than the necessity of introduction. Third, the results of the FGI analysis on industrial personnel showed a positive response, especially regarding the operation of advanced course due to the expansion of school year. Based on this results, it was proposed to design a more systematic reorganization model and provide policy support, to examine the whole scale expansion through pilot application, and to collect opinions more systematically from industrial field experts on school system reorganization plans.

A Study of Curriculum Changes in Dental Hygiene Department of Colleges (전문대학 치위생과 교육과정 편제의 변화 추이에 관한 연구)

  • Choi, Gyu Yil;Choi, Byung Ok;Choe, Ho Seong
    • Journal of vocational education research
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    • v.29 no.3
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    • pp.85-106
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    • 2010
  • The purpose of this study is to analyze and diagnose the curriculum framework of dental hygiene department. Through document analysis process, this study found several empirical data which could give us a clue to understand characteristics of curriculum changes and factors which have impacts on those changes in curriculum at college level. In this study, we could conclude that even curriculum changes at college level had been influenced by social changes like extention of academic years from 2 years to 3 years and changes in licensure test at national level. And also, essential issues in college curriculum like amount of credits, course titles, and requirements-electives distinction etc. also were changed in accordance to social changes and requests. This study found that there is many difference of objectives, credits and course titles among colleges. For that, colleges will form a consultative group under the college level. Based on these results, we can suggest that college curriculum should be flexibly and effectively adapted to changes coping with social and policy changes.

A Study on the Performance Evaluation of Effectiveness and Satisfaction of Veteran Medical Service Delivery System : Focused on the Perspective of Provider and Beneficiary (보훈의료서비스 전달체계의 효과성과 만족도에 관한 성과평가 연구 : 공급자 측면과 수요자 측면을 중심으로)

  • Kim, Yong Hwan;Lee, Hee Sun
    • Korean Journal of Social Welfare Studies
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    • v.47 no.3
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    • pp.187-221
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    • 2016
  • This study examines determining factors of effectiveness and satisfaction of Veteran Medical Service Delivery System. Especially, the association between the relevant variables of the effectiveness of the Veteran Medical Service Delivery System and the variables of the satisfaction from the perspective of beneficiaries was studied. Multi-level analysis was utilized to separate results of the evaluation of effectiveness in organizational-level and the evaluation of satisfaction in individual-level. This study tests key posited hypothesis by using survey data collected from 5 medical center of country(Seoul, Busan, Daejeon, Daegu, Gwangju). In terms of the result of the hypothesis testing on the effectiveness variable, integrity(${\beta}=.156$), accountability(${\beta}=.376$, financial sufficiency(${\beta}=.109$), and adequacy (${\beta}=.367$) are the determinants among various factors in evaluating veteran medical service delivery system, statistically reflecting the perception of directors of the veteran medical service delivery facilities on effectiveness. In other word, professionalism variable(${\beta}=0.99$) and effectiveness variable(${\beta}=-1.09$) are statistically reflecting the perception of directors of the beneficiaries satisfaction with employee. The findings suggests that the theoretical and practical implications will improve Effectiveness and Satisfaction of Veteran Medical Service Delivery System.

Development of Instruction Consulting Strategy for Improving Science Teacher's Gaze Empathy Using Eye-tracking (과학교사의 시선 공감 향상을 위한 시선 추적 기반 수업 컨설팅 전략 개발)

  • Kwon, Seung-Hyuk;Kwon, Yong-Ju
    • Journal of Science Education
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    • v.42 no.3
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    • pp.334-351
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    • 2018
  • Teacher's gaze empathy for students in science class is considered to be effective in enhancing the learning effect. Thus, studies on gaze empathy have been conducted, but most of the studies are just to reveal the characteristics of gaze. Therefore, it is necessary to deal with a research to raise the level of science teacher's gaze empathy. The purpose of this study is to develop an instruction consulting strategy based on eye tracking for improving science teachers' gaze empathy. In this study, we selected and analyzed relevant literature on teacher's gaze empathy. We also designed a consulting strategy and then revised the design through expert reviews on validity and reliability. The developed consulting strategy was aimed to improve science teacher's gaze empathy and set quantitative goal based on eye tracking. The consulting strategy consisted of six steps: preparation for consulting, measurement and analysis of teacher's gaze empathy, instruction and feedback of gaze empathy, training for improving gaze empathy, evaluation of consulting result, and completion of the consulting. In addition, the consultation was completed or repeated again through the measurement and evaluation of gaze empathy using eye tracking. The developed consulting strategy has a value in that it provides an alternative with quantitative diagnosis and prescription for improving gaze empathy. The strategy can contribute to enhance teacher professional competency through the analysis of teaching behavior.

A Research on the Use of Faceted Navigation of KOLIS-NET (KOLIS-NET의 패싯 네비게이션 활용에 관한 연구)

  • Yoon, Cheong-Ok
    • Journal of the Korean Society for Library and Information Science
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    • v.53 no.1
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    • pp.109-132
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    • 2019
  • The purpose of this study is to examine and propose to improve the features of a simple keyword search box and faceted navigations of KOLIS-NET operated by the National Library of Korea. A record group of '2011-2020 (776)' under 'Publication date' facet, out of 3,702 records retrieved from a search of '김훈', were examined. Major findings are as follows: (1) Five facets including 'Format', 'Publication date', 'Subject', 'Language' and 'Country' are used to limit search results only in the first step, and multiple facets cannot be simultaneously used; (2) With 'Publication date' facet formed in the span of ten years, a separate publication year cannot be identified; (3) 'Subject' facet based on KDC limits the results only in broad subject classes without sub-facets; (4) Under 'Format' facet, a special format such as large print texts cannot be identified; (5) Without 'Author' facet, authors cannot be identified; and (6) 'Publication date missing', 'Language missing', and 'Miscellaneous subject' record groups cannot be clicked and displayed, a navigation to-and-fro between a brief list and bibliographic records is not smooth, etc. Therefore an application of multiple facets in all stages of limiting the search result, a construction of sub-facets for 'Publication date' and 'Subject' facets, an accurate description and coding of 'General Material Designation', etc. are suggested to improve KOLIS-NET's faceted navigation.

Developement of Small 360° Oral Scanner Embedded Board for Image Processing (소형 360° 구강 스캐너 영상처리용 임베디드 보드 개발)

  • Ko, Tae-Young;Lee, Sun-Gu;Lee, Seung-Ho
    • Journal of IKEEE
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    • v.22 no.4
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    • pp.1214-1217
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    • 2018
  • In this paper, we propose the development of a Small $360^{\circ}$ Oral Scanner embedded board. The proposed small $360^{\circ}$ oral scanner embedded board consists of image level and transfer method changing part FPGA part, memory part and FIFO to USB transfer part. The image level and transmission mode change unit divides the MIPI format oral image received through the small $360^{\circ}$ oral cavity image sensor and the image sensor into low power signal mode and high speed signal mode and distributes them to the port and transfers the level shift to the FPGA unit. The FPGA unit performs functions such as $360^{\circ}$ image distortion correction, image correction, image processing, and image compression. In the FIFO to USB transfer section, the RAW data transferred through the FIFO in the FPGA is transferred to the PC using USB 3.0, USB 3.1, etc. using the transceiver chip. In order to evaluate the efficiency of the proposed small $360^{\circ}$ oral scanner embedded board, it has been tested by an authorized testing institute. As a result, the frame rate per second is over 60 fps and the data transfer rate is 4.99 Gb/second

Guidelines and Status of Hospital Library in Korea: for Patients and Carers (국내 병원도서관 관련 기준 및 현황)

  • Rhee, Hey Young
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.29 no.4
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    • pp.179-202
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    • 2018
  • This study examined and analyzed the related study, Library Law, comparison of Korean Library Standards and IFLA guidelines and the status of domestic hospital library provision in order to grasp the regulations and status of domestic hospital library. As a result, the related study is very insufficient compared to overseas, and the Law and Standards for hospital libraries are not clearly and in detail in the Library Law. It is impossible to grasp the statistics and actual condition of the hospital library through the Yearbook of the Korean Library. The Korean Library Standards and IFLA guidelines also show differences in composition and key elements. According to the survey, 49 hospitals (1.3%), 8 hospitals (0.2%), 5 nursing hospitals (0.1%), 4 children's hospitals (0.1%), and 1 military hospital (0.0%) were among the 67 hospitals surveyed. Of the 49 general hospitals, 42 were advanced general hospitals, of which 17 were providing hospital libraries. The most urgent issue for providing hospital libraries is the revision of the Library Law and the Korean Library Standards, and the mandatory provision of hospital libraries, publicity through library magazines, and related research should be carried out.

The Trends and Prospects of ICT based Education (ICT를 활용한 교육의 동향과 전망)

  • Woo, Hyun-Jeong;Jo, Hye-Jeong;Choi, Yool
    • Informatization Policy
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    • v.25 no.4
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    • pp.3-36
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    • 2018
  • This article discusses the possibilities and limitations of ICT education by reviewing the previous research on its various aspects including educational goals, contents, methods, and evaluation. First, when it comes to its educational goal, the prior studies suggest that ICT education aims to nurture digital citizenship among students and to enable them to participate in different sectors of our society. ICT education characterizes the core capacities of its future learners as 'lifelong learners,' 'information producers/consumers,' and 'local/global citizens.' Second, in regard to the educational content of ICT education, researchers investigate SW education importantly: They develop the educational programs and examine the effectiveness of those programs. However, to ensure the relevancy of the educational contents to the future society, institutional support is imperative including facilitating educators' capacities and synchronizing ICT education with subject education. Third, as the educational methods, various ICTs such as flipped learning and augmented reality (AR) are being applied to actual classroom teaching. Research on the educational methods, which is the most vibrant area in the ICT education scholarship, is expected to improve the previous educational methods and to lead the qualitative development of ICT education. Fourth, the previous discussion on the educational evaluation focuses on computer-based evaluations. Educational evaluation using ICT will enable educators to assess the characteristics and achievement of an individual learner accurately and to lead them to apply a teaching-learning process effectively, which will ultimately enhance the effectiveness of educational evaluation. Along with the overall review on the possibilities of ICT education, this article discusses the limitations of the current ICT education and its implications for educational inequalities.

Development and Usability of a Cognitive Rehabilitation System Based on a Tangible Object for the Elderly (고령자를 위한 실감객체기반 인지재활 시스템의 개발과 사용성 연구)

  • Park, Sangmi;Won, Kyung-A;Shin, Yun-Chan;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.8 no.1
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    • pp.51-62
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    • 2019
  • Objective: To develop and verify the usability of a cognitive rehabilitation system with diverse cognitive functional levels based on tangible objects for the elderly population. Methods: A study was conducted to investigate the system's strengths and weaknesses by upgrading it with responses from two groups of 15 patients and 4 occupational therapists. After undergoing three forms of training - regarding executive function, memory, and concentration for a total of 20-30 min, the participants were asked to answer a structured questionnaire about contents of the three forms of training, hardware including the tablet PC functioning as a CPU and display media and tangible objects, and satisfaction of experiential usage of the system. Results: Both groups responded that the most interesting training area was executive function while the least interesting was concentration. Six participants reported that the size of the screen of the tablet PC was inappropriate, and five responded that the size of the tool was inappropriate. All therapists and 40% of the patients responded that they were satisfied with this system. Conclusion: This system's features include easy manipulation of tangible tools for performing training tasks, easy selection of and training in cognitive areas based on users' needs, and automatic adjustment of difficulty level based on users' performance. The training environment was designed to be similar to the natural environment by using tangible objects in both hands as input devices for the system, and the system was considered as an alternative to the lack of community cognitive rehabilitation specialists.