• Journal of Hospice and Palliative Care
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• v.21 no.4
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• pp.158-162
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• 2018

Breast cancer related lymphedema (BCRL) is one of the most intractable complications after surgery. Patients suffer from physical impairment, as well as psychological depression. Moreover, a recent study revealed that cellulitis significantly increased the risk of BCRL, and cellulitis has been suggested as a risk factor of BCRL development. We describe a patient treated with stellate ganglion blocks (SGBs) without steroid for relief of symptoms and reduction of the arm circumference of breast cancer-related infectious lymphedema in a month. We measured the arm circumference at four locations; 10 cm and 5 cm above and below the elbow crease, numeric rating scale (NRS) score, lymphedema and breast cancer questionnaire (LBCQ) score on every visit to the pain clinic. A serial decrease of the arm circumference and pain score were observed after second injection. In the middle of the process, cellulitis recurred, we performed successive SGBs to treat infectious lymphedema. The patient was satisfied with the relieved pain and swelling, especially with improved shoulder range of motion as it contributes to better quality of life. This case describes the effects of SGB for infectious BCRL patients. SGB could be an alternative or ancillary treatment for infectious BCRL patients.

• Korean Journal of Psychosomatic Medicine
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• v.30 no.2
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• pp.112-118
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• 2022

Objectives : Zolpidem is a common drug used in insomnia. However, there are several reports of side effects of the central nervous system or sleep related behavior in patients who took zolpidem. This study was conducted to investigate risk factors affecting sleep related behavior after taking zolpidem in inpatients. Methods : From January 1, 2019 to December 31, 2019, medical records of patients who took zolpidem hospitalized at Inha University Hospital were reviewed retrospectively. Results : 907 patients who took Zolpidem, 102 (11.2%) showed sleep related behavior, and if they were 65 years of age or older, men, taking antipsychotics, and taking antipsychotics and benzodiazepines at the same time, they were significantly more likely to show sleep related behavior. Conclusions : Risk factors for sleep-related behavior after use of zolpidem are estimated gender, elderly, antipsychotics, and combination of antipsychotics and benzodiazepines.

• Journal of agricultural medicine and community health
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• v.47 no.2
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• pp.78-89
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• 2022

목적: 이 연구는 2019학년도 역학조사관 입문교육 과정에 참여한 29명의 수습과정생에게 참여형 자기주도 학습 역학조사관 연수 프로그램(FETP)의 효과와 만족도 등 역량 변화를 분석해 그 결과를 향후 과정 개발의 참고 자료로 활용하고자 하였다. 방법: 교육 프로그램의 만족도와 교육 후 모듈에 대한 역량 변화를 평가하는 연구가 수행되었다. 만족도와 역량의 차이 비교는 크루스칼 왈리스 검정(Kruskal-Wallis test)를 실시하였고, 역량의 차이는 윌콕슨 부호순위검정(Wilcoxon signed rank test)에 의해 이루어 졌다. 결과: 2019년 FETP에 참여한 역학조사관 중 여성은 48.3% 였으며, 40세 미만은 9.4% 였다. 역학조사관 입문교육과정 모듈(역학조사, 보건통계 및 정보통계, 감염병 국가 체계, 감염병 질환 감시 체계, 진단 및 실험실 검사, 생물 안전 및 관리, 주요 감염성질환 관리와 조사, 커뮤니케이션, 협동과 리더십, 일반과정)별 만족도는 실무적 도움, 전문성, 기능, 태도 등에서 4점(5점 만점)을 초과하였고, 전체 4.2±0.21(5점 만점)점으로 높은 수준이였다, 모듈의 교육훈련 전후 평균 점수는 2.25±0.91, 3.68±0.63점 등으로 유의한 향상이 있었으며, 모든 모듈 및 하위 주제들도 유의한 향상이 있었다(p<0.001). 그 중에서 현장역학조사 경험이 가장 높은 변화가 있었고, 표본 수집과 실무가 가장 낮은 역량 변화가 있었다. 결론: 2019년 진행된 입문교육 과정은 수료 후 학생들의 역량은 개선되었고, 만족도는 높은 편이었다. 참여형 자기주도학습의 촉진은 역량을 향상시킬 뿐만 아니라 보건 종사자들의 자신감을 높일 수 있었다.

• Journal of the korean academy of Pediatric Dentistry
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• v.50 no.3
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• pp.307-317
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• 2023

Due to increasing demand for aesthetics, zirconia crowns have become a popular choice for treating primary molars. However, there is limited literature available comparing the survival rates of zirconia crowns with those of other restorative materials. The objective of this study was to compare the 36-month survival rates of zirconia crowns and stainless steel crowns for proximal caries, as well as to analyze failure types associated with each crown type. Electronic medical records and radiographs of 1,061 primary molars from 498 patients treated with 2 types of prefabricated crowns at Chosun University Dental Hospital and 2 private dental clinics between 2017 and 2019 were collected and analyzed. The survival rate of zirconia crowns was found to be lower compared to that of stainless steel crowns. Regarding the groups without pulp treatment, the survival rate of stainless steel crowns was significantly higher than that of zirconia crowns. However, in the groups that received pulp therapy, no significant difference in the survival rates was observed between the two preformed crowns. Notably, abnormal root resorption or periapical lesions were identified as the primary cause of restorative failure in stainless steel crowns, whereas loss of restoration was the predominant cause in zirconia crowns. This study holds valuable implications for clinicians when selecting preformed crowns for primary molars.

• School Mathematics
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• v.9 no.2
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• pp.181-196
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• 2007

It would have a trouble to communicate mathematically without an appropriate use of mathematical language. Therefore it is necessary to form mathematics classroom culture to encourage students to use mathematical language precisely. A four-month teaching experiment in a 4th grade mathematics class was conducted focused the accurate use of mathematical language. In the course of the teaching experiment, children became more careful to use their language precisely. The use of demonstrative pronouns such as this or that as well as the use of inaccurate or wrong expressions was diminished. Children became to use much more mathematical symbols and terms instead of their imprecise expressions. The result of the experiment suggests that the culture that encourage students to use mathematical language precisely can be formed in elementary mathematics classroom.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.4
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• pp.378-384
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• 2021

Objectives: Horse trainers ensure the horses they are training and monitor horse's health, hygiene. While most of the studies on horse trainer's health focused on musculoskeletal disorders, few studies have examined the health effect of occupational exposure. This study aimed to investigate the risk of lung cancer in Korean Horse trainers. Methods: Among the largest health screening program of health screening service of the National Health Insurance Corporation, 2,246 workers were selected for study. We utilized data from the National Health Insurance Service (NHIS) National Cohort Data Base 2005-2017. We performed analyses using a Cox's proportional hazards model to identify the risk of lung cancer in Horse trainers. Results: This study found that the horse trainers group had a higher risk of lung cancer 10.07 (95% CI :2.38-42.64) compared to other occupational group. Additionally, there was 6.5 times higher risk of lung cancer in non-smoker horse trainers group. Conclusions: We, thus, verified horse trainers could have relation with increase of lung cancer risk. As lung cancer is known as a cancer with a high contribution of occupational factors compared to other cancers, it is necessary to determine the efficacy of continuous attention and active management of occupational exposure.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.1
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• pp.1-16
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• 2019

Objectives The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine in molluscum contagiosum in China, and to seek better methods to treat and study for molluscum contagiosum in Korea. Methods We searched the clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) by key words '傳染性軟?', '治療', '中?治療', '中藥' from January 2001 to August 2018. We analyzed the literature in regards to the treatment methods and results. Results Among the 103 searched studies, 9 randomized controlled trials, 2 controlled clinical trials, and 16 case studies were selected and analyzed. In most of the studies, the effectiveness of herbal medicine on molluscum contagiosum was significantly high. The most commonly used herbs for oral administration were Isatidis Radix (板藍根), Coicis Semen (薏苡仁), Cyperi Rhizoma (香附子), Equiseti Herba (木賊), Poria (茯?), Lithospermi Radix (紫草), Isatidis Folium (大靑葉) and Lonicerae Flos (金銀花). The most commonly used herbs for external applications were Isatidis Radix (板藍根), Lonicerae Flos (金銀花), Cyperi Rhizoma (香附子), Equiseti Herba (木賊), Dictamni Radicis Cortex (白鮮皮), Isatidis Folium (大靑葉) and Brucea javanica (鴉膽子). Conclusions Based on the results of the clinical studies from China, the use of Korean medicine for treatment of molluscum contagiosum has been shown to be effective in relieving symptoms. Based on the result of this study, it will be possible to widen the scope of Korean medicine on infectious disease, such as molluscum contagiosum. Additional clinical studies and experimental studies need to be performed to solidify these findings.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.3
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• pp.82-102
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• 2019

Objectives The purpose of this study is to investigate clinical studies on the efficacy and safety of herbal medicine inhalation therapy in children by analyzing recent randomized controlled trials conducted in China. Methods We searched the clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) using a by key word '霧化吸入' and specific criteria from 1st January 2010 to 2nd July 2019. Data regarding years of publication, demographic information, target diseases or symptoms, treatment methods, outcome measure, results and adverse events are collected for this study. Results Total of 44 randomized controlled trials were selected and analyzed. Respiratory diseases and symptoms (84.1%) were the most frequent target diseases that herbal medicine inhalation therapy was used. Acute stomatitis was another disease state that the therapy was used. In most of the studies, the herbal medicine inhalation in children showed significant efficacies. The most commonly used herbal medicines were Ephedrae Herba (麻黃), Lonicera Flos (金銀花), Armeniacae Semen (杏仁), Glycyrrhizae Radix et Rhizoma (甘草), Scutellaria Radix (黃芩), Forsythia Fructus (連翹) etc. Hardly any adverse effects were reported from the trials selected. Conclusions Based on the results of the clinical studies from China, herbal medicine inhalation therapy in children can be an effective and safe option for treatment and symptom improvement.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.33-41
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• 2021

Background/Objectives: Extra-nodal extension (ENE) is one of the strongest prognosticators in oral cancers. Here we tried to evaluate clinicopathological factors associated with the presence of ENE. Materials & Methods: We retrospectively analyzed clinical information of 120 patients who diagnosed with oral cancer and received curative surgery at our hospital from Mar 2012 to Apr 2020. We comparatively analyzed clinicopathological factors associated with the presence of lymph node (LN) metastasis and ENE, respectively. Results: Variable factors of primary tumor characteristics such as lymphovascular invasion, perineural invasion, largest diameter of tumor, depth of invasion and maximum standardized uptake value were significantly associated with the presence of cervical LN metastasis. The largest diameter of tumor was statistically significant also in multivariate analysis for predicting the LN metastasis. Meanwhile, the association between primary tumor characteristics and the presence of ENE were not statistically significant except the primary tumor size. Importantly, factors associated with LN characteristics including the maximum diameter and number of metastatic LNs were significantly associated with ENE. Conclusion: In this study, several factors affecting cervical LN metastasis and ENE in oral cancer patients were identified. The ENE seems to be influenced by the status of the metastatic LNs, such as the number of metastatic LNs, rather than the characteristics of the primary tumor itself.

• Korean Journal of Schizophrenia Research
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• v.23 no.2
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• pp.65-70
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• 2020

Objectives: This study aimed to explore whether common genetic variants that confer the risk of schizophrenia have similar effects between Korean and European ancestries using the polygenic risk score (PRS) analysis. Methods: Study subjects included 713 Korean patients with schizophrenia and 497 healthy controls. The Korea Biobank array was used for genotyping. Summary statistics of the most recent genome-wide association study (GWAS) of the European population were used as baseline data to calculate PRS. Logistic regression was conducted to determine the association between calculated PRS of European patients with schizophrenia and clinical diagnosis of schizophrenia in the Korean population. Results: Schizophrenia PRS was significantly higher in patients with schizophrenia than in healthy controls. The PRS at the p-value threshold of 0.5 best explained the variance of schizophrenia (R²=0.028, p=4.4×10^-6). The association was significant after adjusting for age and sex (odds ratio=1.34, 95% confidence interval=1.19-1.51, p=1.1×10^-6). The pattern of the association remained similar across different p-value thresholds (0.01-1). Conclusion: Schizophrenia PRS calculated using the European GWAS data showed a significant association with the clinical diagnosis of schizophrenia in the Korean population. Results suggest overlapping genetic risk variants between the two populations.