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Anti-diabetic peptides derived from milk proteins (우유단백질 유래 혈당 조절 기능성 펩타이드)

  • Kim, Seonyoung;Imm, Jee-Young
    • Food Science and Industry
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    • v.51 no.4
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    • pp.302-312
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    • 2018
  • Bioactive peptides generated from milk proteins play an important role in the prevention and alleviation of diabetes. Whey proteins possess direct insulinotropic effect by amino acids (especially branch chain amino acids) produced through its gastrointestinal digestion. Additionally, blood glucose level can be lowered by gut hormone which called incretin [glucose dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)]. However, physiological effects of incretin readily disappeared by dipeptidyl peptidase-4 (DPP-4) causing degradation of GLP-1. Several DPP-4 inhibitors are currently used as therapeutic medicines for the treatment of type II diabetes. More than 60 natural peptide (2-14 amino acids) DPP-4 inhibitors were identified in milk proteins. Peptide DPP-4 inhibitors act as substrate inhibitor and delay breakdown of GLP-1 both in vitro and in vivo. This review summarizes nutritional quality of milk proteins, absorption and mode of action of bioactive peptides, and finally up-to-dated knowledge on DPP-4 inhibitory peptides derived from milk proteins.

Big Data Utilization and Policy Suggestions in Public Records Management (공공기록관리분야의 빅데이터 활용 방법과 시사점 제안)

  • Hong, Deokyong
    • Journal of Korean Society of Archives and Records Management
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    • v.21 no.4
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    • pp.1-18
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    • 2021
  • Today, record management has become more important in management as records generated from administrative work and data production have increased significantly, and the development of information and communication technology, the working environment, and the size and various functions of the government have expanded. It is explained as an example in connection with the concept of public records with the characteristics of big data and big data characteristics. Social, Technological, Economical, Environmental and Political (STEEP) analysis was conducted to examine such areas according to the big data generation environment. The appropriateness and necessity of applying big data technology in the field of public record management were identified, and the top priority applicable framework for public record management work was schematized, and business implications were presented. First, a new organization, additional research, and attempts are needed to apply big data analysis technology to public record management procedures and standards and to record management experts. Second, it is necessary to train record management specialists with "big data analysis qualifications" related to integrated thinking so that unstructured and hidden patterns can be found in a large amount of data. Third, after self-learning by combining big data technology and artificial intelligence in the field of public records, the context should be analyzed, and the social phenomena and environment of public institutions should be analyzed and predicted.

A Study on Application of Archival Information Services Based on Metaverse (메타버스 기반 기록정보서비스 적용 방안 연구)

  • Kim, Hyunjin;Yim, Jinhee
    • The Korean Journal of Archival Studies
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    • no.74
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    • pp.119-153
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    • 2022
  • Metaverse combines the real and virtual worlds to create a world where all experiences and activities in the real world are possible even in the virtual world without time and space constraints. Currently, metaverse technology is expanding and converging into the realms of society, economy, and culture. In particular, the MZ generation, the main user base, is engaged in various cultural activities such as games, contents, culture, exhibitions, and performances in the metaverse world. Archives, one of the cultural institutions, should provide a new type of service by fusion of Archival information services with metaverse technology so that the MZ generation can know the value and meaning of archives. This will arouse the interest of the MZ generation, which will naturally increase the awareness of the archives, increase visits and use, and will serve as an opportunity to expand the user base. Therefore, in this study, the concept, type, and characteristics of each service were examined, and the representative metaverse platform for each service was selected and a platform utilization plan suitable for Archival information services such as exhibition, experience, and publicity was proposed. In addition, by using 'Spatial', a blockchain-based social metaverse platform, to directly produce exhibition contents, we want to check the considerations suggested, the production process, and the advantages of the metaverse exhibition.

The Anthropocene and the Humanities - Future of the Earth and the Humanities Envisioned by the Ecofeminism of Carolyn Merchant's (인류세와 인문학 -캐롤린 머천트의 생태 페미니즘이 조망하는 지구와 인문학의 미래)

  • Lee, Yun-Jong
    • Journal of Popular Narrative
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    • v.27 no.2
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    • pp.265-291
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    • 2021
  • This paper explores the academic topography of the discourses on the anthropocene to delve into how the humanities can insightfully respond to the ecological crisis of the Earth through the lens of environmental humanities proposed in a 2020 book, The Anthropocene and the Humanities: From Climate Changes to a New Age of Sustainability by a scientific philosopher, Carolyn Merchant. By publishing her latest book, The Anthropocene and the Humanities, Merchant, a pioneering scholar of ecofeminism, has recently started into inquiring into the discourses on the anthropocene, meaning a geological age led by anthropos/humans. In one of her most distinguished works of 1980, The Death of Nature: Women, Ecology, and the Scientific Revolution, Merchant has revealed that the modern Western perception of nature, often identified with women, have been figuratively killing nature as well as women. Arguing in The Anthropocene and the Humanities that the anthropocene has been enacting a "second death of nature," which has been practically and technially killing nature, Merchant calls for the insight of the environmental humanities that help us to build a "sustainable livelihood" based on the "partnership" between human and nonhuman nature. This paper contemplates on what humanities can do in the era of anthropocenic planetarian crisis with the environmental humanistic alternatives in ecofeminist perspective to overcome the anthropocenic crisis aggravated by the covid-19 occurred at the point when the climate change was viscerally felt by the humans in the twenty first century.

Application and Adequacy Evaluation of Mobile Sewage Treatment Facilities for Concrete Wastewater Treatment Generated during Construction (공사 중 발생되는 콘크리트 폐수처리를 위한 이동식 오수처리 시설의 적용 및 적정성 평가)

  • Wooseok Jeong;Kyungik Gil
    • Journal of Wetlands Research
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    • v.25 no.2
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    • pp.91-98
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    • 2023
  • Some concrete wastewater generated during construction is in the form of non-point pollution sources that workers, managers, and users are unaware of, and it is not easy to manage as it flows through sewage pipes. Due to these characteristics, construction sludge is inflow into rivers and sewage pipes in the form of non-point pollution sources in an unmanaged state. This study applied the D.W.S method to the concrete retaining wall removal method installed on the road, and the resulting concrete wastewater was physically and chemically treated through a mobile sewage treatment facility, and it was examined whether it met the removal efficiency and wastewater discharge acceptance standards. Accordingly, it is intended to meet the standards for effluent concentration of wastewater during construction by removing 73.5% of BOD and 89.1% of SS through physical and chemical treatment through portable sewage treatment facilities during construction. In addition, we would like to review the adequacy and economic analysis of calculating environmental conservation costs for physicochemical treatment through portable sewage treatment facilities and sewage treatment generated during construction.

A study on method of acquisition of modernity in comic narrative;in 『Byeolgeongon』 (웃음서사의 근대성 획득방식 연구;『별건곤』을 중심으로)

  • Lim, Seon-Ae
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.3
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    • pp.151-161
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    • 2017
  • In the period of Japanese occupation comic narratives were popular to such an extent as to be published not only newspapers and magazines but also books as 『Yojigyeong』(1910), 『Jeodobaekhwa』(1912), 『Gaegeonhuihui』(1912), 『Angcheondaeso』(1913), 『Kkalkkaluseum』(1916), 『Socheonsoji』(1918), 『Gogeumgidamjip』(1923), 『Mangogidam』(1924), 『Joseonpaldo iksal & jaedam』(1927), 『Segyesohwajip』(1934). This study is to discuss about how those narratives gain modernity with the titles scattered in 『Byeolgeongon』 as the central figure, and to reveal the nature of the comic narratives in 『Byeolgeongon』 by looking into contents. The comic narratives in the magazine are 149, especially from the titles show the editors' agony at that time. The narratives gain modernity by combining the new trend cultural terms which can't be found in our traditional culture as 'sinbu huboja jeonramhwoe.', 'sinrang huboja jeonramhoe.', 'nonsense teuksseolgwan', 'how modern shipbuilding 10 inventions sinjejo', 'sohwabangsongsil', 'sohwabangsongguk', 'freedom march', 'sinchunpoksodaehwoe' and 'humor orchestra'. The narratives give laughter to the readers by carrying the characters such as wit, enlightenment, critics of social conditions, grotesque. The narratives in the magazine 『Byeolgeongon』 represent much to survive with comic story in a time of gloom in the period of Japanese occupation.

A Servicism Model of the New Society and Education System (서비스주의 사회교육시스템의 구조와 운용 연구)

  • Hyunsoo Kim
    • Journal of Service Research and Studies
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    • v.11 no.3
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    • pp.75-97
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    • 2021
  • This study was conducted to derive a society and education system model that will improve the happiness and sustainability of human society. An ideological model for making human society a happy society was derived, and a society and education system structure and operation model based on this was presented. A fair society, a justice society, a mutually considerate society, and a society where individuals are happy are the conditions for a sustainable society. After analyzing the current situation of freedom and equality pursued by capitalism and democracy, which are currently adopted by most societies, an improvement model was derived from the perspective of a sustainable society. The cost of freedom and equality were analyzed and a new alternative system was discussed. The social solidarity and class mobility issues were discussed together and servicism was derived as an alternative solution. It is a system in which two opposing opponents of individual freedom and social norms form a symmetrical balance, and material and spiritual values are balanced. Servicism is a dynamic balance model. That is, the dimensions of time and space are involved. It is a model that maintains a thorough balance through a dialectical process as time and space change, and one value can dominate the other at a specific time or space. The service-oriented society and education system is a system that simultaneously pursues the goals of individual happiness and sustainable development of the social community.

A Study of Daesoon Jinrihoe's View of Time (I): Focusing on Time as Measured and Experienced (대순진리회의 시간관 연구 (I) - 측정되고 경험되는 시간을 중심으로 -)

  • Cha Seon-keun
    • Journal of the Daesoon Academy of Sciences
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    • v.48
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    • pp.1-40
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    • 2024
  • Time can be the fundamental basis of religious doctrine and the foundation for a life of faith. Therefore, understanding a religion's interpretation of time and exploring its perception is accepted as one of the approaches to comprehending its principles. Based on this idea, this article delves into how chronos (measured time) and kairos (experienced time) are manifested in Daesoon Jinrihoe. In Daesoon Jinrihoe, the moment when chronos and kairos intersect is considered a moment of spiritual experience. Ethical codes are accomplished in the midst of the process of defining this time as the Heavenly Dao and adjusting human affairs accordingly. These ethics lead individuals towards a religious life. East Asian traditions also apply this logic, but Daesoon Jinrihoe differs in that it emphasizes reinterpreted ethics. Furthermore, Daesoon Jinrihoe posits that Degree Numbers (度數) are a device that ensures the transition from chronos to kairos. Degree Numbers, which are both a law of the universe's motion and a function of time, were emphasized by the Kang Jeungsan when he advocated for the discarding of old ways and the creation of the new ways. He thereby urged humans to live in accordance with time. Time is also facilitated in the dimension of ritual observances and participation, with examples including prayers, devotional offerings, and holy works (gongbu, 工夫). Those rituals of Daesoon Jinrihoe actively incorporate a unique basis of reason for this style of engagement with time, which is one of the aspects that is held to secure justification.

Technology to Remove Trace Pollutants in Sewage Treatment Water Using Jellyfish Characteristics (해파리의 특성을 활용한 하수처리장 처리수 내 미량오염물질 제거 기술)

  • Hyeok Jin Park;Eun Jin Kim;Kyung Sil Choo;Joo Eun Shim;Min-Kyeong Yeo
    • Applied Chemistry for Engineering
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    • v.35 no.1
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    • pp.54-60
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    • 2024
  • The present study was aimed to evaluate the removal of the trace pollutants (heavy metals and microplastics) in the sewage treatment plant by using the jellyfish Extract at Immunity reaction (JEI) of Aurelia coerulea. The experiment was conducted on two different scales: the lab scale using a Jar-tester and the Pilot system scale equipped with two newly developed devices in the laboratory, the active tube connection mixed system and the concentration integrated separation device. Compared to anionic polymers currently used in the field, JEI showed similar or higher efficiency to remove the trace pollutants. When JEI was added to the effluent through the Pilot system, the combination of JEI and the trace pollutants was maximized through two mixing processes, and as a result, the removal rate of the trace pollutants was greatly improved. Based on these results, we propose the present technology as an alternative to removing trace pollutants that can reduce ecosystem risk and minimize the generation of inorganic waste, away from the existing method.

A study on automated soil moisture monitoring methods for the Korean peninsula based on Google Earth Engine (Google Earth Engine 기반의 한반도 토양수분 모니터링 자동화 기법 연구)

  • Jang, Wonjin;Chung, Jeehun;Lee, Yonggwan;Kim, Jinuk;Kim, Seongjoon
    • Journal of Korea Water Resources Association
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    • v.57 no.9
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    • pp.615-626
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    • 2024
  • To accurately and efficiently monitor soil moisture (SM) across South Korea, this study developed a SM estimation model that integrates the cloud computing platform Google Earth Engine (GEE) and Automated Machine Learning (AutoML). Various spatial information was utilized based on Terra MODIS (Moderate Resolution Imaging Spectroradiometer) and the global precipitation observation satellite GPM (Global Precipitation Measurement) to test optimal input data combinations. The results indicated that GPM-based accumulated dry-days, 5-day antecedent average precipitation, NDVI (Normalized Difference Vegetation Index), the sum of LST (Land Surface Temperature) acquired during nighttime and daytime, soil properties (sand and clay content, bulk density), terrain data (elevation and slope), and seasonal classification had high feature importance. After setting the objective function (Determination of coefficient, R2 ; Root Mean Square Error, RMSE; Mean Absolute Percent Error, MAPE) using AutoML for the combination of the aforementioned data, a comparative evaluation of machine learning techniques was conducted. The results revealed that tree-based models exhibited high performance, with Random Forest demonstrating the best performance (R2 : 0.72, RMSE: 2.70 vol%, MAPE: 0.14).