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Blood Pressure in Relation to α-Adducin, Angiotensinogen, ACE Gene Polymorphisms and Sodium Intake in Korean Female Elderly Subjects (한국 여성 노인에서 α -Adducin, Angiotensinogen, ACE 유전자다형성 및 나트륨 섭취수준에 따른 혈압의 비교)

  • Chae, Sun-Ju;Chung, Ja-Yong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1371-1377
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    • 2006
  • Gene polymorphisms that are associated with sodium homeostasis in the body, such as $\alpha-adducin$ (ADDI, Gly460Trp), angiotensinogen (AGT, Met235Thr), and angiotensin converting enzyme (ACE, Ins/Del) may increase the risk for the development of hypertension. The purpose of this study was to elucidate the relationship between the singular and combined effects of ADD1, AGT, ACE genotypes, and blood pressure in elderly population. Moreover, we examined the interaction of sodium intake and polymorphisms of aforementioned genes and their effects on blood pressure. Among one hundred and nine female subjects, aged 60 and over (mean 75.9 yr), the major alleles for ADD1, AGT, and ACE polymorphisms in the studied population were Gly (66.1%), Thr (64.2%), Ins (83.5%), respectively. Analysis on the combined effects of genetic variation showed that subjects who were both ADD1 Trp/Trp and ACE Del/Del homozygotes had significantly higher systolic blood pressure (p=0.01). Similarly, ACE Del/Del homozygotes who had AGT Met allele had significantly higher diastolic blood pressure (p<0.001). However, in single-gene analyses, no association was found between any specific genotype and blood pressure. In subjects with low sodium intake, ADD1 Trp/Trp homozygotes had significantly higher systolic blood pressure than subjects who had ADD1 Gly allele (138 mmHg vs. 127 mmHg, p=0.03). There was no difference in blood pressure between ADD1 Trp/Trp and ADD1 Gly/Gly or Gly/Trp, in subjects with high sodium intake. In summary, this study shows that interactions between the ADD1, AGT and ACE genes influence systolic and diastolic blood pressure in elderly subjects, and dietary sodium intake can modulate the effects of ADD1 Gly460Trp polymorphisms on systolic blood pres sure.

Clustering according to Inpatients' Opinion on Hospital Foodservice and Analyzing Inpatient Response to Foodservice Qualify and Revisit Intention by the Cluster: In Case of S Hospital (입원환자의 급식서비스 인식에 따른 고객 군집화 및 군집별 급식서비스 질 평가, 재이용 의도 분석: S병원을 대상으로)

  • Lee, Hae-Young;Chang, Seung-Hee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1491-1497
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    • 2006
  • The purpose of this study was to analyze the relationship among inpatients' perceptions of foodservice quality, satisfaction and revisit intention. Questionnaires were hand-delivered to 350 inpatients and a total of 230 questionnaires were usable (response rate 65.7%), Statistical data analysis was completed using the SPSS Win 11.0 for descriptive analysis, independent t-test, $x^2$ test and k-means cluster analysis. The results of this study can be summarized as follows: The average score of overall importance of meal service in medical service was 4.25 out of 5.0, yet the score of overall quality of meal service and value had lower than importance score. A helpfulness to medical treatment (3.48), bringing customer happiness (3.18), overall satisfaction for foodservice (3.66), satisfaction based on expectation before discharge (3.53) and offering foodservice apt to hospital reputation (3.40) were measured as expressions of satisfaction. As a result of clustering analysis, two clusters were classified and named as affirmative opinion group and negative one. Expectation for four factors of foodservice quality between two groups had no significance. But affirmative opinion group had significantly higher score than negative one in perception and satisfaction. Affirmative customers' intention to revisit in the near future was evaluated as high in both considering general medical service (4.04) and reflecting meal service level (3.84).

A Study on Correlations between Dietary Nutrients and Body Composition of College Students (남녀 대학생의 영양소 섭취 상태와 체성분 조성의 상관관계)

  • Chung, Hee-Chung;Chang, Kyung-Ja
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1378-1384
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    • 2006
  • A survey was conducted for 221 male and 191 female college students to study correlations between dietary food intakes and body composition. Among the subjects 75 male and 82 female students were analyzed body protein mass, body mineral mass, percent body fat, waist-hip ratio (WHR), body mass index (BMI) and fitness score using Inbody 3.0. The results show that 94.6% of the males and 24.7% of the females were observed at high level in body protein mass. As for body mineral mass, 86.4% of the males were observed below the normal range. As for WHR, 32.1% of the males and 43.5% of the females were evaluated as abdominal obesity. As for BMI, 34.8% of the males were observed above the normal range. In female students, correlation coefficient between sodium intakes and age showed significantly negative 0.232 while correlation between calcium intakes and self-reported health status showed significantly positive 0.234. In males, correlation coefficient between fiber intakes and self-reported health status resulted in significantly positive 0.237 and that between BMI and age showed significantly positive 0.276. In females, correlation coefficient between type of living and WHR showed significantly positive 0.253 and that between self-reported health status and percent body fat showed significantly positive 0.230. Also correlation coefficient between body protein mass and sodium intakes showed significantly negative 0.276 in female students.

Effect of Larva Extract of Allomyrina dichotoma on Carbon Tetrachloride-induced Hepatotoxicity in Mice (장수풍뎅이 유충 추출물이 사염화탄소에 의한 마우스의 간 손상에 미치는 영향)

  • Choi, Yong-Hwa;Lee, Ki-Yeol;Yang, Kyung-Mi;Jeong, Yun-Mi;Seo, Jung-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1349-1355
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    • 2006
  • This study was conducted to investigate the effect of methanol extract of Allomyrina dichotoma larva (MEAL) on carbon tetrachloride $(CCl_4)-induced$ hepatotoxicity in mice. ICR mice were divided into 5 groups [Vehicle control, $CCl_4\;(10{\mu}g/g)$ alone, $CCl_4$ plus a low dose $(50{\mu}g/g)$ of MEAL, $CCl_4$ plus a high dose $(100{\mu}g/g)$ of MEAL]. Silymarin $(2{\mu}g/g)$ was used as the reference in the experiment. Administration of MEAL tended to decrease the serum alanine transaminase (ALT) activity induced by $CCl_4$ treatment in mice. Hepatic concentration of thiobarbituric acid-reactive substances (TBARS) in a high-dose group of diet decreased to the level of silymarin-treated group. Hepatic activity of glutathione S-transferase in MEAL-treated group was lower than that of $CCl_4-treated$ group. Serum concentration of bilirubin was significantly increased by $CCl_4$ treatment, but MEAL or silymarin recovered the level. These results suggest that MEAL may exert the protective effect against $CCl_4-induced$ hepatotoxicity in mice. However, more intensive studies would be needed to elucidate the protective mechanism of the beetle on hepatotoxicity of mice.

Characteristics of Soil Erosion on the Forest Fired Sites by Using Rainfall Simulator (인공강우장치를 이용한 산불발생지의 토양침식 특성에 관한 연구)

  • Lee, Heon Ho;Joo, Jae Duk
    • Journal of Korean Society of Forest Science
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    • v.95 no.6
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    • pp.649-656
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    • 2006
  • The purpose of study is to measure soil erosion quantity for elapsed four years from the fire on forest fired sites of Dong-gu, Daegu. This study was conducted to investigate the characteristics of soil erosion by fire occurrence influencing on the soil erosion were. Also analysis result follows that the relations between soil erosion quantity and rainfall intensity, the slope and elapsed year. The results analysed were as follows: 1. Soil erosion by year of occurrence of forest fire was increased 1.9 to 5.7 times as rainfall intensity was increased by 30 m/hr, and 1.4 to 14.2% as degree of slope was increased by $10^{\circ}$. 2. In the first year of forest fire occurrence, soil erosion was fairly heavy for 10 minutes of initial rainfall of which rainfall intensity was 80 m/hr and degree of slope was $30^{\circ}$. The amount of soil erosion was gradually reduced as elapsed time. From two years after fire, the amount of soil erosion by rainfall intensity and degree of slope was nearly constant. 3. The amount of soil erosion by rainfall intensity and slope in accordance with elapsed time after fire was reduced 28.9 to 94.1% in three years after occurrence of forest fire as compared to the first year of fire. Soil erosion was fairly heavy by rainfall intensity and slope in the first year of fire, but it was gradually reduced from two years after fire. 4. In the analysis on influences of each factors on the amount of soil erosion on forest fired sites, the amount of soil erosion was significant differences in major impacts of each rainfall intensity, degree of slope and elapsed year after fire and interaction of rainfall intensity${\times}$degree of slope and rainfall intensity${\times}$elapsed year after fire, but no differences were observed in interaction of degree of slope${\times}$elapsed year after fire and rainfall intensity${\times}$degree of slope${\times}$elapsed year after fire. Rainfall intensity was the most affecting factor on the amount of soil erosion and followed by degree of slope and elapsed year after fire. 5. For correlation between soil erosion and affecting three factors, soil erosion showed significant positive relation with rainfall intensity and degree of slope at I % level, and significant negative relation with elapsed year after fire at 1 % level. 6. As a result of regression of affecting three factors on soil erosion. rainfall intensity was most significant impact factor in explaining the amount of soil erosion on forest fired sites, followed by degree of slope and elapsed year after forest fire. 7. The formula for estimating soil erosion using rainfall intensity, degree of slope and elapsed year after forest fire occurrence was made. S.E = 0.092R.I + 0.211D.S - 0.942E.Y(S.E : Soil erosion, R.I : Rainfall intensity, D.S : Degree of slope, E.Y : Elapsed year after forest fire occurrence)

Effect of Soil Moisture and Weather (atmospheric) Conditions on the Fruiting of Sarcodon aspratus in Oak Stand (토양수분과 가상인자가 참나무림내 능이의 발생에 미치는 영향)

  • Lee, Sang-Hee;Kim, Je-Su;Kim, Hong-Eun;Koo, Chang-Duck;Park, Jae-In;Shin, Chang-Sop;Shin, Won-Sop
    • Journal of Korean Society of Forest Science
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    • v.94 no.6
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    • pp.370-376
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    • 2005
  • Sarcodon aspratus is well known as a natural edible mushroom and a symbiotic mycorrhizal fungus with oaks. This study was conducted to clarify the effects of environmental conditions on the fruiting of S. aspratus on the hillslope of Wolak Mt., Jecheon city, Chungbuk, South Korea. Soil moisture and soil temperature in S. aspratus colony were measured hourly and compared with those in the non-colony soil. The mean soil moisture during the mushroom development was 14.3% in the colony soil and 16.4% in the non-colony soil. The S. aspratus colony soils showed 2.1% less soil moisture. The mean soil temperature was $16.8^{\circ}C$ in the colony soil and $16.5^{\circ}C$ in the non-colony soil. The S. asprauts colony soils showed slightly higher temperature. It is considered that more soil water was consumed and more energy was emitted during the mycelial elongation and the mushroom development. The development of S. aspratus seems similar to that of T. matsutake which is known to be considerably affected by soil moisture, daily maximum air temperature, daily minimum air temperature and daily minimum soil temperature. The season of S. aspratus development ranges from the end of August to the beginning of October. And Ellino phenomenon and its unusual change in the weather seems to affect primodia and fruiting body development. Especially if daily minimum soil temperature continues to become higher than $20^{\circ}C$, the damage of primodia and its fruiting body was frequently observed in the field plots during the last few years recently.

Properties and Suitability of Bark Extractives from Larix leptolepsis as a Bonding Agent (낙엽송(落葉松) 수피추출물(樹皮抽出物)의 특성(特性)과 접착제화(接着劑化)의 적합성(適合性))

  • Oh, Jung Do;Ahn, Won Yung
    • Journal of Korean Society of Forest Science
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    • v.77 no.3
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    • pp.294-302
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    • 1988
  • The experiment was carried out to investigate the properties of bark extractives form Larix epilepsies and to evacuate their suitability as a bonding agent. The yield and reactivity were measured to examine the influence of temperature and time and the effect of carbonation and sulfonation. To define the possibility of practical application as wood adhesives the viscosity and gelation time were measured at 33% concentration. The results obtained were summarized as follows : 1. As the both yield and reactivity were high, extraction for 2 hours at $80^{\circ}C$ was the optimal temperature and time. 2. The highest effect achieved at 1% $Na_2CO_3$ about carbonation and 1% $Na_2SO_3$ : $NaHSO_3$ and 0.25% $Na_2SO_3$ about sulfonation. The sulfonation of 0.25% $Na_2SO_3$ increased the yield and reactivity most highly. 3. By using hot water as extraction liquid the yield was 17.2%, while the addition of 1% and 5% NaOH to the extraction liquid increased the yield to 38.6% and 44.6%, respectively. 4. Hot water extracts showed the highest reactivity(68.8%). The addition of 1% and 5% NaOH led to decrease in reactivity(49.3% and 25.8%, respectively). 5. At 33% concentration of the extracts the viscosity appeared very variable. Significantly high values of viscosity was measured in 1% NaOH solution, while very low values appeared for 5% NaOH solution. 6. The shortest gelation time was determined at pH 7 to 10 and the highest at pH 4. The use of paraformaldehyde resulted in gelation times longer than those of 37% formaldehyde solution. 7. Except the sulfonation extracts of hot water and 1% NaOH, the other extracts were found unsuitable due to high viscosity(1% NaOH extracts, sulfonation extracts) or to curing inability(5% NaOH extracts, sulfonation extracts of 5% NaOH). 8. From the three extract solutions which appeared to be suitable for use as bonding agents the hot water extracts and the sulfonation extracts of hot water were superior in extract reactivity, while the sulfonation extracts of 1% NaOH exceeded the other two extracts in extract yield.

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Improvement on Fish Odor of Extracts from Salmon Frame Soaked in Soybean Milk (두유 전처리에 의한 열수추출 연어 Frame 엑스분의 비린내 개선)

  • Heu, Min-Soo;Park, Shin-Ho;Kim, Hye-Suk;Kim, Hyung-Jun;Han, Byung-Wook;Ji, Seong-Gil;Kim, Jeong-Gyun;Yoon, Min-Seok;Kim, Jin-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.2
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    • pp.223-230
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    • 2008
  • For the use of extracts from salmon frame as a basic material of Gomtang-like products, various methods (soaking into soybean milk, adding anchovy, and adding spices) for masking fish odor into extracts from salmon frame were examined and the food component characteristics were also compared with commercial Gomtang. According to the results of volatile basic nitrogen, transmission at 660 nm and sensory evaluation of extracts, soaking treatment, which is the soaking of salmon frame into soybean milk, was the most efficient method among the various methods for masking fish odor into extracts from salmon frame. There was no difference in the proximate composition between extracts from salmon frame soaked (FS) and unsoaked (C) into soybean milk. The FS was not detected in heavy metals, such as chromium, lead and cadmium. The taste value of FS (16.26) was higher than that of C and the major amino acids were glutamic acid and aspartic acid. Total amino acid content of FS (3.08 g/100 mL) was also higher than those of C (2.95 g/100 mL) and commercial Gomtang (1.70 g/100 mL), and the major amino acids were glycine, proline, glutamic acid and arginine. The calcium and phosphorus contents of FS/500 mL accounted for 21.7% and 18.5%, respectively, of the recommended daily allowance of mineral for adult.

Effect of Grain Size and Added Water on Quality Characteristics of Abalone Porridge (쌀 입자 크기 및 물 첨가량에 따른 전복죽의 품질 특성)

  • Shin, Eun-Soo;Lee, Kyong-A;Lee, Hye-Kyung;Kim, Koth-Bong-Woo-Ri;Kim, Mi-Jung;Byun, Myung-Woo;Lee, Ju-Woon;Kim, Jae-Hun;Ahn, Dong-Hyun;Lyu, Eun-Soon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.2
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    • pp.245-250
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    • 2008
  • The purpose of this study was to evaluate quality of abalone porridge prepared with different sizes of rice and amounts of added water. pH of porridge was mostly stable from 6.3 to 6.8 but as more water was added, pH increased. Increase of added water resulted in higher TBARS value, but most of TBARS value was generally low, and there wasn't any significant difference. Lightness of the rice powder porridge was 53 to 59 and it was higher than that of round rice porridge. Redness tended to be high as rice size was bigger and less amount of water was added. Yellowness of round rice porridge and half rice porridge was higher than that of rice powder porridge. Also, yellowness of porridge had a tendency to decrease as amount of water was increased. Consistency, viscosity, and firmness was higher in round rice porridge and half rice porridge than in rice powder porridge, and increase in added water amount led to decrease of all textural properties. In the measurement of texture properties that is only present in rice grain, the hardness, gumminess, and chewiness of round rice grain porridge was significantly higher than that of half rice. In the sensory evaluation result, all sensory properties was significantly different (p<0.05) among the abalone porridges prepared with different rice sizes and added water. The viscosity, flavor, texture, and taste of half rice abalone porridge added 1000 mL water showed the highest sensory scores.

Inhibitory Effects of Ethanol Extracts from Polygoni multiflori radix and Cynanchi wilfordii radix on Melanogenesis in Melanoma Cells (하수오와 백하수오의 에탄올 추출물에 의한 B16/F10 Melanoma 세포주의 멜라닌 생성 억제효과)

  • Seo, Hee;Seo, Geun-Young;Ko, Su-Zie;Park, Young-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.8
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    • pp.1086-1091
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    • 2011
  • Anti-oxidative activity and tyrosinase inhibitory activity of various ethanol extracts of Polygoni multiflori radix (PMR) and Cynanchi wilfordii radix (CWR) were compared to identify an anti-oxidant and whitening agent source from nature. We conducted an investigation into the anti-oxidant activities of PMR and CWR ethanol extracts by measuring total polyphenol content, total flavonoid content, and ABTS radical capacity. The total polyphenol contents of PMR and CWR were 17.31${\pm}$0.54 mg GA/eq g, and 2.75${\pm}$0.22 mg GA/eq g, respectively. The total flavonoid contents of PMR and CWR were 6.38${\pm}$0.39 mg naringine/eq g, and 1.34${\pm}$0.09 mg naringine/eq g, respectively. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) radical decolorization of PMR and CWR were 96.89${\pm}$0.21% at 1 mg/mL and 93.49${\pm}$0.76% at 50 mg/mL. Melanoma cells were cultured with the PMR and CWR ethanol extracts for 48 hr, and total melanin content as a final product and the activity of tyrosinase, a key enzyme, in melanogenesis, were estimated. The PMR and CWR ethanol extracts increased melanin content and tyrosinase activity in a dose-dependent manner. These results suggest that PMR and CWR ethanol extracts could be useful as a skin whitening agent.