• Journal of Life Science
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• v.33 no.2
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• pp.183-190
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• 2023

Red yeast rice, also known as Hong Qu and red Koji, has been used for a long time in Asian functional food and traditional medicine. It consists of multiple bioactive substances, which can potentially be used as nutraceuticals. Alcoholic liver disease (ALD) can range from simple steatosis or inflammation to fibrosis and cirrhosis, possibly through leaky gut and systemic endotoxemia. This study examined the liver and gut effects of red yeast rice (RYR) (Monascus purpureus) ethanol extract against binge ethanol-induced liver injury in mice. RYR extract was orally administered to C57BL/6N mice at a concentration of 200 mg/kg body weight per day for 10 days. Then, mice were administered binge alcohol (5 g/kg/dose) three times at 12 hr intervals. Binge alcohol exposure significantly elevated the endotoxin, aspartate aminotransferase (AST), and alanine transaminase (ALT) activity of plasma, as well as hepatic triglyceride levels; however, RYR treatments reduced these levels. In addition, RYR pretreatment significantly reduced the alcohol-induced oxidative maker protein and apoptosis maker in binge alcohol-induced gut and liver injuries. These results suggest that RYR may prevent alcohol-induced acute leaky gut and liver damage.

• The Korean Journal of Applied Statistics
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• v.36 no.2
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• pp.141-166
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• 2023

This paper investigates synthetic data generation methods and their evaluation measures. There have been increasing demands for releasing various types of data to the public for different purposes. At the same time, there are also unavoidable concerns about leaking critical or sensitive information. Many synthetic data generation methods have been proposed over the years in order to address these concerns and implemented in some countries, including Korea. The current study aims to introduce and compare three representative synthetic data generation approaches: Sequential regression, nonparametric Bayesian multiple imputations, and deep generative models. Several evaluation metrics that measure the utility and disclosure risk of synthetic data are also reviewed. We provide empirical comparisons of the three synthetic data generation approaches with respect to various evaluation measures. The findings of this work will help practitioners to have a better understanding of the advantages and disadvantages of those synthetic data methods.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.506-506
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• 2022

비점오염원에서 배출되는 오염부하량(BOD, T-P)은 점오염원의 2배 이상을 차지하고 있어 비점오염원 관리에 대한 관심이 증대되고 있다. 이에 비점오염원의 효율적 관리를 위한 전략 및 추진과제 마련을 위해 제1차('04-'11), 제2차('12-'20) 비점오염원 관리 종합대책(이하 종합대책)이 수립 및 이행되었다. 이어 2016년 물환경보전법 개정에 따라 종합대책의 수립이 법제화되고 지난 2020년 말 제3차 비점종합대책('21~'25)이 수립되었다. 제3차 비점종합대책은 수질개선이 체감되는 비점오염원 관리라는 비전을 가지며 도시, 농·축산, 산림, 관리기반의 4개 분야에 총 71개의 세부 추진과제를 제시하고 있다. T-P 비점오염배출부하량 5% 감축, 불투수율 감축, 비점오염관리지역개소 확대, 고랭지 흙탕물 관리지역 구역 확장, 지역 거버넌스 구축을 대책의 목표와 각 분야별 관리지표로 제시하고 있다. 물환경보전법 제53조의5와 동법 시행령 제75조의3에 따라 환경부장관은 매년 이행사항을 점검 및 평가하여 그 결과를 비점오염원 관리 정책의 수립 및 집행에 반영해야 한다. 지난 제1·2차 대책의 경우 성과 점검 및 관리를 위한 체계가 부재하여 사업의 실효성 확보에 한계가 있었으며 이에 따라 소관별 이행사항 점검 및 평가체계의 필요성이 제기되었다. 따라서 본 연구에서는 종합대책 이행평가 전략 및 세부 추진체계를 마련하여 효율적인 소관별 이행사항 점검 및 평가를 도모하고자 하였다. 분야별 세부 추진과제는 매년, 대책의 목표와 각 분야별 관리지표는 대책 시행 후 5차년에 점검 및 평가할 수 있도록 구성하였다. 또한 종합대책의 최종 목표 달성 시뮬레이션을 통해 5차년 이후 원활한 평가가 이루어질 수 있도록 하였다. 본 연구에서 마련한 이행평가 체계를 통해 적절한 이행평가 및 효율적인 비점오염원 관리를 도모할 수 있을 것으로 사료된다.

• Journal of Korean Society of Forest Science
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• v.112 no.4
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• pp.544-553
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• 2023

The purpose of this study was to reveal the thermal comfort and physiological and psychological effects of spending time in broad-leaved forests in suumer. Thirty-one university students (with an average age of 21.4 ± 2.1 years) participated in the study, and a within-subjects experimental design methodology was used. The participants moved to an experimental site (with a crown closure of 76.6%) or a control site (25.9%), sat on a chair to eliminate the impact of movement, and rested for 5 minutes with closed eyes. At this time, thermal comfort, heart rate variability, heart rate, and forehead temperature were continuously measured. After that, blood pressure and pulse rate were measured, and a subjective evaluation was conducted. As a result, spending time at an experimental site showed a statistically significant decrease in the predicted mean vote and the percentage of dissatisfied values, enhancement of parasympathetic nerve activity, decrease of forehead temperature, diastolic blood pressure, heart rate, pulse rate, and improvement of personal thermal sensation (thermal sensation vote and comfort sensation vote). In conclusion, it was found that a forest with high crown closure reduces thermal stress and induces physiological and psychological relaxation.

• Proceedings of the Korean Society of Food Hygiene and Safety Conference
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• 2002.05a
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• pp.3-42
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• 2002

21세기에는 인구의 폭발적 증가와 함께 가속화된 산업화로 말미암아 경지 면적은 줄고 농업 환경은 더욱 피폐해질 것으로 예상된다. 지금도 이미 화석 에너지원의 고갈로 대체 에너지 개발이 시급히 요구되고 있으며, 지구의 자연 환경 보존 목소리도 그 어느 때 보다 높다. 한마디로 식량, 에너지, 환경 문제가 새 세기에 우리가 시급히 해결해야할 과제로 주어져 있다. 이에 과학계에서는 식량 및 대체 에너지원의 공급을 증대시키고 환경을 보존할 수 있는 보편적인 수단으로 환경 친화적 유전자 변형 (GM)작물의 활용이 제시되고있다. 따라서 선진국들은 이의 기반이 되는 식물유전체 연구에 대규모 투자를 아끼지 않고 있으며, 이를 이 용한 식물 생명공학산업을 국가 전략 산업으로 집중 육성하고 있다. GM작물 제조 기술은 유용 유전자의 발굴 및 재조합, 식물세포로의 이식 및 재분화를 통한 완전한 식물체 재생, 이를 품종으로 실용화하는 단계로 구성되어 있다. GM작물은 1983년 항생제 저항성 담배가 개발된 것을 시점으로 하여, 1994년에는 연화지 연 토마토 Flaver Saver이후 지금까지 개발 실용화된 작물은 제초제 저항성 콩, 카놀라, 목화, 그리고 해충 저항성 옥수수 등이 있으며,2001년까지 세계적으로 상품화 승인을 얻은 경우는 15 작물 68품종에 이른다. 2001년 경우 GM작물 종자시장은 약 30억 달러에 달하고 있으며, 미국, 아르헨티나, 캐나다 등 세계적으로 52.6백만 ha에 이르는 면적에서 재배되었다. 그러나 GM농산물의 식품 및 환경 안전성에 대한 의구심이 일기 시작하였고, 따라서 이의 생산 및 소비에 대한 전반적 인 문제가 뜨거운 쟁점으로 부각되기도 하였다. 이 에 각국 정부는 객관적 인 안전성을 확보하기 위한 제도적인 장치를 마련하고 있으며, 아울러 과학기술자들은 더욱 안전한 형질전환 기술 개발을 도모하고 있다. 다음 세대의 GM작물은 단순한 제초제 및 병해충 저항성을 넘어서서 특정 영양 또는 건강기능성을 향상시켜 부가가치를 증가시킨 신품종 맞춤작물이 지속적으로 개발 상업화될 것이다. 따라서 고유성을 가진 유용 유전자의 대량 확보 여부가 산업적 경쟁력을 결정하게 될 것이다. 지금까지 개별 유전자 중심으로 이루어지던 유용 유전자 발굴 작업은 유전체학의 출현으로 규모가 대량화되고 그 효율이 증진되었다. 따라서 진 각국은 유용 유전자 발굴에 국가적 차원의 역량을 집중하고 있다. 그러나 우리나라는 정부와 민간의 소규모 지원으로 근근히 기술 습득 차원에 머물러 왔으며, 산업적 경쟁력의 무기가 될 고유한 유용 유전자와 형질전환 기술이 거의 없는 어려운 상황에 놓여 있다. 최근 정부가 시작한 생명공학 분야 대규모 연구지원 사업 기대를 모아 보며 이 분야 과학기술자들의 노력을 촉구한다.

• Korean Journal of Breeding Science
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• v.41 no.3
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• pp.236-243
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• 2009

This study was conducted to develop a japonica-type rice cultivar with brown planthopper (BPH) resistance using DNA markers. A doubled haploid (DH) population consisting of 120 pure-lines was established by anther culture of $F_1$ hybrids between 'Samgang', a Tongil type BPH resistance cultivar, and 'Nagdong', a japonica cultivar. To determine the map position of genes responsible for BPH resistance in rice, a genetic map was constructed based on 120 DH lines. A total of 162 molecular markers were classified into 12 linkage groups, covering 1,884 Kosami centimorgan (cM) with an average of 11.6 cM. Five QTLs (qBPR3, qBPR6, qBPR7, qBPR8, and qBPR12) associated with BPH resistance were identified and mapped on chromosomes 3, 6, 7, 8, and 12, respectively, using the genetic map constructed in this study. To analyze the relationship between BPH resistance and agronomic traits, a total of eight QTLs related to the agronomic traits were detected on 12 rice chromosomes. In an analysis of relationships, three QTLs (qBPR3, qBPR7, and qBPR8) showed a linkage with tested agronomic traits. A QTL (qBPR3) located on chromosome 3 (RM282-3023) was closely linked to culm length (qCL3). The QTL (qBPR8) for BPH resistance on the short arm of chromosome 8 also overlapped the region detected in culm length (qCL8).

• Journal of Climate Change Research
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• v.3 no.1
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• pp.39-50
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• 2012

KMA(Korea Meteorological Administration) projected that annual mean temperatures of South Korea will rise $3.8^{\circ}C$ and the annual total precipitation will increase by 17 percent by 2100. Rainfall is concentrated during the summer in South Korea. Thus the risk of landslide by heavy rain is expected to increase. After the landslide of Mt. Umyeon occurred in July 2011, disaster of forest sector is highlighted. Therefore vulnerability assessment of landslide is urgent. However, vulnerability assessment based on local governments was not done yet. In this study, we assess vulnerability of landslide by heavy rain for local governments. We used several scenarios to consider uncertainty of climate change. Through this study, local governments can use the results to establish adaptation plans. Also, the results could be used to decrease vulnerability of landslide.

• Journal of the Korean earth science society
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• v.43 no.1
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• pp.30-40
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• 2022

Wildfires, which occur sporadically and irregularly worldwide, are distinct natural disturbances in combustible vegetation areas, important parts of the global carbon cycle, and natural disasters that cause severe public emergencies. While many previous studies have investigated the variability and changes in wildfires globally based on fire emissions, burned areas, and fire weather indices, studies on East Asia are still limited. Here, we explore the characteristics of variability and changes in wildfire danger over East Asia by analyzing the fire weather index for the 40 years-1981-2020. The first empirical orthogonal function (EOF) mode of fire weather index variability represents an increasing trend in wildfire danger over most parts of East Asia over the last 40 years, accounting for 29% of the total variance. The major contributor is an increase in the surface temperature in East Asia associated with global warming and multidecadal ocean variations. The effect of temperature was slightly offset by the increase in soil moisture. The second EOF mode exhibits considerable interannual variability associated with the El Nino-Southern Oscillation, accounting for 17% of the total variance. The increase (decrease) in precipitation in East Asia during El Nino (La Nina) increases (decreases) soil moisture, which in turn reduces (increases) wildfire danger. This dominant soil moisture effect was slightly offset by the temperature increase (decrease) during El Nino (La Nina). Improving the understanding of variability and changes in wildfire danger will have important implications for reducing social, economic, and ecological losses associated with wildfire occurrences.

• Membrane Journal
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• v.34 no.2
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• pp.87-95
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• 2024

Recent studies explore a wide array of desalination and water treatment methods, encompassing membrane processes such as reverse osmosis (RO), nanofiltration (NF), and electrodialysis (ED) to advanced capacitive deionization (CDI) and its membrane variant (MCDI). Comparative analyses reveal ED's cost-effectiveness in low-salinity scenarios, while hybrid systems (NF-MCDI, RO-NF-MCDI) show improved salt removal and energy efficiency. Novel ion separation methods (NF-CDI, NF-FCDI) offer enhanced efficacy and energy savings. These studies also highlight the efficiency of these methods in treating complex wastewater specific to various industries. Environmental impact assessments emphasize the need for sustainability in system selection. Additionally, the integration of microfabricated sensors into membranes allows real-time monitoring, advancing technology development. These studies underscore the variety and promise of emerging desalination and water treatment technologies. They provide valuable insights for enhancing efficiency, minimizing energy usage, tackling industry-specific issues, and innovating to surpass conventional method limitations. The future of sustainable water treatment appears bright, with continual advancements focused on improving efficiency, minimizing environmental impact, and ensuring adaptability across diverse applications.

• Journal of Information Management
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• v.20 no.2
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• pp.69-99
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• 1989

With regard to system configuration, file structure and function, this study has compared and analyzed KITLAS developed by KIT Library and CD-ROM BiblioFile, which is selected among CD-ROM Catalog Production Products, the mass storage media, produced by the fast-growing laser technology and information technology. Furthurmore, this study illuminates how to improve the reliability of bibliographic database, implementing downloading and uploading processes which make possible the conversion and online, mass transmission of CD-ROM MARC records at once.