• Title/Summary/Keyword: 고지된 동의

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Effects of Stephaniae Tetrandrae Rhizoma and Sinomenii Caulis on Hyperlipidemia in Rat (분방기(粉防己)와 청풍등(淸風藤)이 고지혈증(高脂血症) 흰쥐에 미치는 효과)

  • Shih, Chen-Kuo;Lee, Young-Jong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.2
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    • pp.495-500
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    • 2005
  • To compare the efficacy of Stephaniae Tetrandrae Rhizoma and Sinomenii Caulis which are medicinal plants used as Bang Kee(防己), the plants were combined with Astragali Radix and Lycopii Herba into 6 different medicinal decoctions. The specimen decoctions prepared were each decoctions of Stephaniae Tetrandrae Rhizoma(St), Sinomenii Caulis(Si), Stephaniae Tetrandrae Rhizoma-Astragali Radix(StA), Stephaniae Tetrandrae Rhizoma-Lycopii Herba(StL), Sinomenii Caulis-Astragali Radix(SiA) and Sinomenii Caulis-Lycopii Herba(SiL). They were dosed to rats with induced hyperlipidemia. In the groups of rats with hyperlipidemia induced by high cholesterol diet, in the group which St was dosed to, there was no significant effect on the level of Tc, TG, HDLc. And in the group which Si was dosed to, the level of Tc, TG dropped and that of HDLc rose. In the groups of rats with hyperlipidemia induced by high cholesterol diet, in the group which StA was dosed to, there was no significant change in the level of Tc, TG, or HDLc. But in the group which SiA was dosed to, the level of Tc and TG dropped and that of HDLc rose. In the groups of rats with hyperlipidemia induced by high cholesterol diet, in the group which StL was dosed to, the level of TG dropped, but there was no significant change in the level of Tc or HDLc. And in the SiL group, there was no significant change in the level of Tc or TG, but the level of HDLc rose. On diseases such as hyperlipidemia, when using drug couple of Bang Kee-Astragali Radix as a treatment, Sinomenii Caulis is recommended rather than Stephaniae Tetrandrae Rhizoma, and when using drug couple of Bang Kee-Lycopii Herba as a treatment, Sinomenii Caulis and Stephaniae Tetrandrae Rhizoma neither showed significant effect. And as Lycopii Herba interrupts the effect of Sinomenii Caulis, drug couple of Sinomenii Caulis-Lycopii Herba is not recommended.

Anti-Obesity Effects of Lactic Acid Bacteria-Fermented Dioscoreae Rhizoma Powder on High Fat Diet-Fed Animal Model (고지방식이에 의한 비만 동물모델에서 유산균 마분말의 항비만 효과)

  • Park, Young Mi;Oh, Hong Geun;Kang, Yang Gyu;Kim, Young Pill;Sin, Hong Sig;Jang, Seung Hwan;Kim, Hee Jeong;Lee, Sang Wang;Lee, Hak Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.29 no.3
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    • pp.267-272
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    • 2015
  • The purpose of this study was to examine the antiobesity effects of lactic acid bacteria-fermented Dioscoreae Rhizoma powder (LDR) in Sprague-Dawley rats with high-fat diet (HFD)-induced obesity. Rats were divided into 5 groups: normal diet group, control (high fat diet-vehicle) group, 0.4 g/kg LDR (high fat diet + 0.4 g/kg lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 1 g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 2.5g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group. Our results indicate that LDR administration has effects on decreasing of body weight, fat weight, blood parameters and adipocyte size in the obesity animals. In addition, verified that fat degeneration and ballooning degeneration were alleviated in the experimental group fed on a high fat diet combined with LDR groups. These results indicate that lactic acid bacteria-fermented Dioscoreae Rhizoma powder may reduce elevating body weight and lipid accumulation in rat fed a high fat diet, suggesting its usefulness as a functional food for reducing body fat and obesity.

Inhibitory Effects of Bogigambi-tang on the Obese-mouse Induced by High Fat Diet (보기감비탕(補氣減肥湯)이 고지방사료 식이로 비만이 유발된 생쥐에게 미치는 영향)

  • Choi, Jung-Sik;Oh, Min-Seok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.3
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    • pp.634-641
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    • 2007
  • In order to investigate the effects of Bogigambi-tang(here in after referred to BGGBT) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high fat diet. C57BL/6 mice were divided into three groups(normal, high fat diet with control, high fat diet with BGGBT extract) and fed for 15 weeks. Items of this experimental study are as follows. Body weight change, final inclose of body weight, the weight change of the adipocytes in body, the level change of ALT, AST, total cholesterol, LDL-Cholesterol, triglyceride, glucose, free fatty acid and creatinine, the expression of ${\beta}$3AR and leptin gene in primary adipocytes, the production change of leptin in primary adipocytes, the expression of ${\beta}$3AR and leptin in adipocytes tissue. The following results have been obtained All experimental group have shown that the weight and the final increase of weight have decreased considerably. All experimental group have shown that the amount of the adipocyte in weight has decreased considerably. All experimental group have shown that the amount of leptin has decreased considerably. All experimental group have shown that the revelation of ${\beta}$3AR in primary adipose cell and 3T3-L1 cell has increased considerably, and that the revelation of leptin in primary adipose cell and 3T3-L1 cell has decreased considerably, All experimental group have shown that the size of adipocyte in adipocytes tissue has decreased. The high density group have shown that the adipose vacuoles in liver tissue has decreased considerably, and that the cell nucleuses has similar with normal group.

Optimal Node Analysis in LoRaWAN Class B (LoRaWAN Class B에서의 최적 노드 분석)

  • Seo, Eui-seong;Jang, Jong-wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2019.05a
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    • pp.100-103
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    • 2019
  • Due to the fourth industrial revolution called 'fusion and connection', interest in 'high connectivity society' and 'highland society' is increasing, and related objects are not limited to automation and connected cars. The Internet of Things is the main concern of the 4th Industrial Revolution and it is expected to play an important role in establishing the basis of the next generation mobile communication service. Several domestic and foreign companies have been studying various types of LPWANs for the construction of the Internet based on things, and there is Semtech's LoRaWAN technology as representative. LoRaWAN is a long-distance, low-power network designed to manage a large number of devices and sensors, with communications from hundreds to thousands to thousands of devices and sensors. In this paper, we analyze the optimum node capacity of gateway for maximum performance while reducing resource waste in using LoRaWAN.

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A Study on the Conflict between the Use of Personally non-Identifiable Information and the Protection of Personal Information in Digital Behavioral Advertising: Focusing on the Domestic and Foreign Status and System (디지털 맞춤형 광고에서 비식별개인정보의 활용과 개인정보 보호와의 갈등에 관한 연구: 국내외 현황과 제도를 중심으로)

  • Choi, Min-Wook
    • Journal of Convergence for Information Technology
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    • v.11 no.1
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    • pp.71-79
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    • 2021
  • This study looked at the conflict between the aspect of the use of personally non-identifiable information for the development of the big data industry and the digital advertising industry and the aspect of personal information protection. In order to achieve the research purpose, this study focused on literature research such as thesis, legal texts, administrative regulations, and recent media articles. As a result of this study, the main issues related to the protection of personally non-Identifiable Information in digital behavioral advertising were 'conflict between freedom of advertising expression and personal rights', 'personalization of unidentifiable information', 'information imbalance'. In this regard, as measures to protect personally non-identifiable information in digital behavioral advertising, it was proposed to 'harmonize with freedom of advertising expression and personal rights, 'improve notification and consent. process', and 'reinforce the right to control personal information'.

Massa Medicata Fermentata improves fatty liver in high fat diet-fed nonalcoholic fatty liver disease's mouse model (고지방식이 유도 비알콜성지방간 마우스 모델에서 육신국(六神麯)의 지방간(脂肪肝) 개선효과)

  • Roh, Jong Seong;Lee, Hye Rim;Ahn, Ye Ji;Yoon, Mi Chung;Shin, Soon Shik
    • The Korea Journal of Herbology
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    • v.29 no.2
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    • pp.23-31
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    • 2014
  • Objectives : This study was undertaken to verify the effects of Massa Medicata Fermentata (MMF) on nonalcoholic fatty liver disease (NAFLD) using high fat diet-fed male mice. Methods : Fifty four male C57BL/6N mice (age matched) were used for all experiments. Nine standard chow diet-fed mice were used as normal group and forty five high fat diet-fed obese mice were randomly divided into 5 groups: control, atorvastatin-10mg/kg, MMF(1)-62.5mg/kg, MMF(2)-125mg/kg and MMF(3)-250mg/kg. After all groups were treated with several kinds of diets for 8 weeks, we measured body weight gain, adipose tissue weights, plasma lipid and glucose metabolism, visceral organ weights, histological analysis for liver on the mice. Results : MMF-treated mice had lower body weight gain compared with controls. Among MMF-treated mice, the effect was magnified in MMF(2). MMF(3)-treated mice had lower blood plasma total cholesterol (TC) and glucose level compared with controls. MMF decreased hepatic lipid accumulation, liver fibrosis and liver inflammation of mice compared with controls. The effects was maximized in MMF(2) and atorvastatin. Blood plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), ${\gamma}$-glutamyltransferase (${\gamma}$-GT) concentrations tends to be decreased by MMF compared with controls. Blood plasma AST, ALT, ${\gamma}$-GT concentrations and organ weights were not changed by MMF, indicating that all three kinds of MMF do not show any hepatotoxicity. Conclusions : These results suggest that MMF improves NAFLD by reducing body weight gain, hepatic lipid accumulation, liver fibrosis, liver inflammation.

Paleomagnetism of the Tonggo Formation in the Baekunsan Syncline (백운산 향사대에 분포하는 동고층에 대한 고지자기 연구)

  • Doh, Seong-Jae
    • Economic and Environmental Geology
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    • v.26 no.3
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    • pp.383-393
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    • 1993
  • Paleomagnetic data have been obtained from the Lower Triassic Tonggo formation which is exposed in the E-W trending Baekunsan syncline comprising the Pyongan Supergroup in eastern Korea. Two ancient components of magnetization are recovered in this formation by detailed thermal demagnetization: a post-folding component and a pre-folding component The post-folding component ($D/I=58.8/55.5^{\circ}$) is normally magnetized and appears to acquire in the Cretaceous Normal Superchron. It is a magnetic signature of the Daebo Orogeny and has been rotated clockwise since this magnetization has been acquired, in common with the main synclinal axis. The pre-folding component ($D/I=1.1/19.4^{\circ}$, Paleopole at $306.1^{\circ}E$, $63.2^{\circ}N$) passes fold and reversal tests and is inferred to be a post-depositional or early chemical diagenetic remanence of Lower-Middle Triassic age. This paleopole corresponds only with the Lower Triassic poles from the North China Block: it is removed from the contemporary poles from the South China Block. If the result of this study is corrected for the clockwise rotation deduced from the Cretaceous overprint, the enhanced agreement with the Lower Triassic poles from the North China block can be achieved. Therefore, a first order correlation between the Korean Peninsula and North China at least since Lower Triassic times is identified in this study.

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Miniaturization of Log-Periodic Dipole Array Antenna for PS-LTE Service (재난안전 통신망 서비스를 위한 대수 주기 다이폴 배열 안테나의 소형화)

  • Jeon, Hoo-Dong;Heo, Soo-Young;Ko, Ji-Hwan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.28 no.3
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    • pp.170-176
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    • 2017
  • In this paper, we proposed the miniaturized structure of the Log-Periodic Dipole Array(LPDA) antenna for PS-LTE(Pubic Safety-Long Term Evolution) service. The length of array dipole was shortened by adding a fractal tree element with iteration to the array dipole to miniaturize the LPDA antenna. As the result, the proposed LPDA antenna was reduced up to 25 %, compared a typical LPDA antenna. To validation of the proposed LPDA antenna specification, the proposed LPDA antenna is fabricated using aluminum with 1.5 mm thickness and performances are measured. Comparison between simulation result and experiment shows good agreement.

A Paleomagnetic Study of the Tonggo Formation in Tanyang Area (단양지역에 분포하는 동고층에 대한 고지자기 연구)

  • Doh, Seong-Jae;Park, Yong-Hee;Kim, Ji-Youn
    • Economic and Environmental Geology
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    • v.31 no.1
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    • pp.45-52
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    • 1998
  • Paleomagnetic data have been obtained from the Lower Triassic Tonggo Formation which is exposed in Tanyang area comprising the Pyeongan Supergroup in eastern Korea. Mean characteristic direction of the Tonggo Formation is declination/inclination=$121.4^{\circ}/-26.4^{\circ}$ (k=52.7, ${\alpha}_{95}=7.2^{\circ}$, N=9 Sites) and paleopole at longitude/latitude=$30.7^{\circ}E/33.3^{\circ}N$ ($dp/dm=4.2^{\circ}/7.8^{\circ}$). The mean direction passes reversal test and fold test at 99% confidence level. Therefore, it is inferred to be a pre-folding component. The paleopole position of this study is close to the Triassic pole positions of the North China Block; it is far from those of the South China Block. Therefore, a first order correlation between the Korean Peninsula and North China at least since Lower Triassic times is identified in this study.

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A CASE REPORT OF ANTROLITH IN THE MAXILLARY SINUS (상악동에 발생한 동석의 증례보고)

  • Cho Jeong-Shin;Shin In-Sook;Lee Jang-Yeol;Go Jee Young;Kim Sun Yong;Park Chang-Seo;Kim Kee-Deog
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.24 no.1
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    • pp.197-202
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    • 1994
  • The antrolith is a rare disease in the maxillary sinus. We experienced a 67-year-old female whose chief complaint was a intermittent dull pain of clinical, radiological and histological findings, we diagnosed it as antrolith in the left maxillary sinus and obtained results as follows: 1. Three radiopaque substances in the left maxillary sinus was revealed as 'Antroliths'. 2. These antroliths were movable in the left maxillary antrum and combined with maxillary sinusitis. 3. We supposed it internal origin of nidus in this case.

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