• Journal of Korean Clinical Nursing Research
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• v.26 no.1
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• pp.47-58
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• 2020

Purpose: The aim of this study was to develop a simulation-based High Flow Nasal Cannula Oxygen Therapy training program based on NLN/ISF to identify the effect on knowledge, clinical performance, and educational satisfaction compared to a group who had traditional High Flow Nasal Cannula Oxygen Therapy training after applying it to clinical nurses. Methods: 31 experimental groups and 33 control groups were conducted from August 2019 to September 2019 for inexperienced nurses over 4 months to 5 years with no experience using high-flow oxygen therapy. Educational programs were developed in scenarios according to Airvo2 and Optiflow, such as facilitator, participant, educational condition, design, characteristics, and educational outcomes. The education application was conducted in advanced for knowledge and clinical performance ability after watching therapy video. Since then, a total of 90 minutes have been conducted for respiratory failure theory training, airvo2 and optiflow simulation training, and debriefing. After applying the education, the medical institution measured nurses' knowledge, clinical performance, and education satisfaction. Data were analyzed using descriptive statistics, with the SPSS/WIN 22.0 program. Results: Both knowledge and educational satisfaction were higher in the experimental group than in the control group (t=-14.09, p<.001), (t=-12.99, p<.001). The clinical performance for both use of Optiflow and Airvo2 were higher in the experimental group than in the control group (t=-11.39, p<.001), (t=-11.38, p<.001). Conclusion: Results showed that the simulation-based High Flow Nasal Cannula Oxygen Therapy training was effective with the experimental group having increased scores for every area of this study.

• Journal of the Korean Society of Radiology
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• v.16 no.6
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• pp.761-769
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• 2022

Pads with high dielectric materials have been used in a variety of applications to locally improve the field sensitivity and homogeneity of RF pulses in clinical MRI studies. In this study, we aimed to improve such pads in consideration of the practical problems associated with the application of actual clinical images. A high permittivity pad to increase the attenuated B1 field strength was fabricated and tested in 7T MRI. Sim4Life simulation and experimental results show stronger and relatively uniform B1 near field. In order to improve the image quality in the whole cerebellum, known as a region with low sensitivity, a guide was made to reduce the mechanical change of the pad. In order to improve the wearing comfort, the pad was designed by dividing it into upper and lower parts. The facial pad showed an overall signal increase effect in areas such as the turbinate in the nasal cavity. Signal increase was expected in areas such as the frontal lobe and eyes, but the effect was either insignificant or it was difficult to see the effect in the imaging protocol. In conclusion, this paper showed a cerebellar-optimized pad with an improved nasal signal while maintaining its effectiveness.

• Journal of the Korean Society of Radiology
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• v.85 no.3
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• pp.654-660
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• 2024

Primary malignant fibrous histiocytoma (MFH) is a malignant tumor of mesenchymal origin that rarely occurs in the urinary tract, particularly in the urinary bladder. Unlike urothelial carcinoma, which accounts for most bladder cancers, it occurs in the submucosal portion of the bladder wall and consists of the lamina propria, muscularis propria, and adventitia. It is presumed to originate from poorly differentiated pluripotent mesenchymal cells in which fibroblasts and histiocytes are partially differentiated. Radiologically, it is known as the "non-papillary tumor" and is commonly diagnosed as a large mass without necrosis, which shows invasion beyond the muscularis propia. Although the prognosis of this rare malignancy depends on pathological parameters, it generally has a poor prognosis with high local tumor recurrence. Here, we present a case of primary MFH in the urinary bladder with clinical symptoms of lower abdominal pain without gross hematuria that recurred rapidly and showed an aggressive disease course.

• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.1-9
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• 2024

Exosomes are nano-sized membrane-bound extracellular vesicles containing various biological molecules, such as nucleic acids, proteins, and lipids, which can be used to modulate physiological processes. The exosomal molecules secreted by cells can be extensively used as tools for diagnosis and therapy. Exosomes carry specific molecules released by the cells they originate from, which can be transferred to surrounding cells or tissues by the exosome. For these reasons, exosomes can be exploited as biomarkers for diagnosis, carriers for drug delivery, as well as therapeutics. In stem cell technology, exosomes have been an attractive option because they can be used as safer therapeutic agents for stem cell-based cell-free therapy. Recently, studies have demonstrated the safety and efficacy of mesenchymal stem cell-derived exosomes in alleviating symptoms associated with coronavirus disease 2019 as they have anti-inflammatory and immunomodulatory potential. Performing multiple studies on exosomes would provide innovative next-generation options for clinical diagnostics and therapy. This review summarizes the use of exosomes focusing on their diverse roles. In addition, the potential of exosomes is illustrated with a focus on how exosomes can be exploited as powerful tools in the days to come.

• Clinical and Experimental Pediatrics
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• v.51 no.5
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• pp.492-499
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• 2008

Purpose : Helicobacter pylori infection is one of the most common gastrointestinal infections worldwide; it almost invariably causes chronic gastritis. Pediatric studies may provide important insights into the mucosal immune response of H. pylori-infection, as children are not submitted to environmental factors such as alcohol, tobacco and anti-inflammatory medication. The aim of the present study was to investigate the mucosal immune response against H. pylori in clinically well-defined groups: H. pylori-positive (divided into peptic ulcer disease and gastritis) and H. pylori-negative control. Methods : Antral biopsies were obtained from 45 children undergoing an upper GI endoscopy for dyspeptic symptoms. T cells (CD3+, CD4+, CD8+) and B cells (CD20+) were analyzed by quantitative immunohistochemistry. The correlation of lymphocyte subsets of gastric mucosa with histology was evaluated. Results : T cells (CD3+, CD4+, CD8+) and B cells (CD20+) were significantly increased in the lamina propria of H. pylori-positive group (P<0.01). CD8+ T cells were significantly increased in the lamina propria of the H. pylori-positive peptic ulcer disease (P<0.01). Within the epithelium, only CD4+ T cells were significantly increased in the H. pylori-positive group (P<0.01). Gastric histological parameters had a closer correlation with lymphocytes in the lamina propria than intraepithelial lymphocytes. Conclusion : This study suggests that both T cells and B cells in the lamina propria play important roles in the local immune response of H. pylori-infected children. Furthermore, it remains to be elucidated whether CD8+ T cells in the lamina propria may contribute to peptic ulcer formation in H. pylori-infected children.

• The Journal of the Korea Contents Association
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• v.8 no.10
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• pp.251-258
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• 2008

This study was to investigate the effects of the combined patterns of PNF(proprioceptive neuromuscular facilitation) on the static balance ability by 20 subjects for 6 weeks. The combined patterns of PNF were carried out by Sprinter and Skater suggested by Dietz which were practiced once a day, 3 times a week. This study were measured normal standing, one leg left and one leg right standing when eye open and close on GOOD BALANCE system. These result lead us to the conclusion that mean velocity of X,Y direction, COP velocity moment were showed a statically decrease applying post-exercise on Normal Standing Eye Open(NSEO), Normal Standing Eye Close(NSEC), One Leg Right Standing Eye Close(OLRSEC) and Just velocity of X direction were showed a statically decrease applying post-exercise on One Leg Right Standing Eye Close(OLRSEC). The above results from this study indicated that combined patterns of PNF have improved the static balance ability. However the used self-exercise ca be applied to normal people, i.e., the exercise is difficult to apply into clinical patients. The further study should be focused at development of various modified forms of the combined patterns of PNF in keeping up the improvement effect of the exercise.

• The Journal of the Acoustical Society of Korea
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• v.16 no.6
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• pp.36-40
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• 1997

The effectiveness of Extracorporeal Shock Wave Lithotripter(ESWL) for the therapy of calculus has been generally known in the field of urology. However, there are very little paper investigated about physical characteristics of sounds radiated when phantom is shotting with shock waves. Therefore, this paper, firstly, investigates the sounds radiated when impact is applied to the phantom with a single shot by an impact hammer and a clinical ESWL Next, it determines the variance of the sounds radiated during the breaking process using a piece of chalk as a phantom of a calculus. These results will be applied to the examination of the existence of the calculus at the focus and the monitoring the breaking process.

• Journal of Korean Academy of Nursing
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• v.37 no.3
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• pp.286-294
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• 2007

Purpose: The aim of this study was to develop a performance measurement scale for nurses in the hospital setting and to test the reliability and validity of the scale. Methods: This study was conducted in three phases including an application of conceptual framework, development of scale items, and test of validity and reliability of the scale. In order to test validity and reliability, data was collected from 1,966 nurses who work in twenty eight hospitals nation-wide. The data was analyzed by the SAS 8.0 program using descriptive statistics, factor analysis, and reliability coefficients. Results: The Performance measurement scale consisted of 4 factors which included competency, attitude, willingness to improve, and application of nursing process, and a total of 17 items. The Four factors explained 63.45% of the total variance, and Cronbach's alpha of the scale was.92. Conclusion: The performance measurement scale developed by this study is a reliable and valid instrument that is utilized effectively to evaluate the performance of hospital nurses. Furthermore, it could be used as a sloping stone to assess educational needs of nurses, develop professionalism among nurses, and improve quality of nursing care in the hospital setting.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2005.04a
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• pp.93-95
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• 2005

MRS is to measure very small metabolite signals, whose resonant frequencies spread over the chemical shift range characteristic of the measured nucleus. The MR signal originates from the excited volume, which is a column of tissue divided into slices by gradient or rf encoding. The parameters that acquired data affected by TE, TR, and other variables. The higher spatial resolution of 3D CSI compared to SVS and its ability to examine regional metabolite variations for brain study.

• PNF and Movement
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• v.11 no.1
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• pp.43-54
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• 2013

Purpose : The purpose of this research was to verify the effects of the clinical practice and the educational satisfaction through internship program on students of health-related majors. Methods : We investigated 120 students using a self-reporting method with experience of internship program. A statistical analysis was performed using SPSS 17.0 for window version. Results : It showed that educational satisfaction had scored 4.18 in curriculum, 4.16 in environment, 4.16 in schedule, 4.32 in teaching and 3.82 in evaluation, 4.21 in satisfaction for clinical practice. Conclusion : It was revealed by this survey that the educational satisfaction of internship program in school hospital had higher score in curriculum, environment, schedule, evaluation, teaching and clinical practice. To maximize the effects of internship program, a clinical internship program in school hospital is needed and further research and attention are suggested.