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Safety analysis and deterioration evaluation of water pipe for improvement according to service year (상수도관의 개량을 위한 시간에 따른 노후도 및 안전성 분석)

  • Kwon, Hyuk Jae;Lee, Kyung Je
    • Journal of Korea Water Resources Association
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    • v.54 no.8
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    • pp.589-597
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    • 2021
  • In this study, corrosion depth equation was suggested according to real measured corrosion data, and then management indexes of pipe network which can determine the deterioration rate and safety rate has been established and applied to real pipe networks. Furthermore, reliability analysis and management index analysis have been conducted to estimate and compare the deterioration rate. From the results of reliability analysis, it was found that probability of failure of 200 mm steel pipe can be increased from 4.36% at present time to 8.23% after 20years at Gaduk and from 7.35% to 12.99% at Nami. From the results of management index analysis, it was found that deterioration rates of Gaduk and Nami are 1.009 and 1.174, respectively. Priority of improvement and replacement of water pipe can be determined by results of reliability analysis and management index analysis.

농업용수 이용량 산정을 위한 인자 조사

  • Maeng, Seung-Jin
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.48 no.2
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    • pp.9-14
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    • 2006
  • 우리나라의 수자원정책이 과거 개발위주의 정책에서 수요관리 중심의 정책으로 전환됨에 따라 제한된 수자원의 효율적인 활용 차원에서 수자원 개발 및 관리계획 수립의 기초정보인 용수이용량 자료의 신뢰성 확보가 중요하게 되었다. 용수 이용량은 생활, 공업, 농업용수로 대별하여 산정하며 이들 중에서 특히 농업용수의 이용량을 상대적으로 산정하기 어렵다. 농업용수 이용량 산정시 고려되는 인자는 자료의 신뢰성이 우선되어야 수자원계획과 관리에 효율적으로 대처할 수 있을 것이다. 따라서 본고에서는 이러한 농업용수 이용량 산정을 위한 조사인자의 획득 방법과 체계를 다룬 "용수이용조사 합리화 방안 연구(3차)" 보고서(2003. 11, 건설교통부)의 내용을 중심으로 정리하였다. 용수이용량 산정을 위한 조사인자는 수자원계획 및 관리차원에서의 활용측면과 대국민 신뢰도 확보 등 홍보효과 측면 등을 감안하여 종합적으로 고려하였으며 용수수요량을 추정할 경우 필요한 인자에 대해서는 "수자원장기종합계획(2001. 7, 건설교통부/한국수자원공사)"에서 제시된 산정방법을 기준으로 하여 결정하였다.

In silico Analysis of Downstream Target Genes of Transcription Factors (생명정보학을 이용한 전사인자의 하위표적유전자 분석에 관한 연구)

  • Hwang, Sang-Joon;Chun, Sang-Young;Lee, Kyung-Ah
    • Clinical and Experimental Reproductive Medicine
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    • v.33 no.2
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    • pp.125-132
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    • 2006
  • Objective: In the previous study, we complied the differentially expressed genes during early folliculogenesis. Objective of the present study was to identify downstream target genes of transcription factors (TFs) using bioinformatics for selecting the target TFs among the gene lists for further functional analysis. Materials & Methods: By using bioinformatics tools, constituent domains were identified from database searches using Gene Ontology, MGI, and Entrez Gene. Downstream target proteins/genes of each TF were identified from database searches using TF database ($TRANSFAC^{(R)}$ 6.0) and eukaryotic promoter database (EPD). Results: DNA binding and trans-activation domains of all TFs listed previously were identified, and the list of downstream target proteins/genes was obtained from searches of TF database and promoter database. Based on the known function of identified downstream genes and the domains, 3 (HNF4, PPARg, and TBX2) out of 26 TFs were selected for further functional analysis. The genes of wee1-like protein kinase and p21WAF1 (cdk inhibitor) were identified as potential downstream target genes of HNF4 and TBX2, respectively. PPARg, through protein-protein interaction with other protein partners, acts as a transcription regulator of genes of EGFR, p21WAF1, cycD1, p53, and VEGF. Among the selected 3 TFs, further study is in progress for HNF4 and TBX2, since wee1-like protein kinase and cdk inhibitor may involved in regulating maturation promoting factor (MPF) activity during early folliculogenesis. Conclusions: Approach used in the present study, in silico analysis of downstream target genes, was useful for analyzing list of TFs obtained from high-throughput cDNA microarray study. To verify its binding and functions of the selected TFs in early folliculogenesis, EMSA and further relevant characterizations are under investigation.

한국에 있어서의 원자력발전의 전망 (1)

  • 박연용
    • 전기의세계
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    • v.13 no.1
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    • pp.24-29
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    • 1964
  • 원자력발전의 실현성은 그의 경제적 가치에 의하여 결정되나 그 경제적 가치는 그 지역의 전력 수급전망과 "에너지"사정, 공업발전에 관한 사정 등 복잡한 여러 요소에 의하여 결정되는 것이다. 이와같은 인자를 현재 얻을 수 있는 개략적인 자료에 의거 분석하여 원자력의 경제성을 검토하고 한국에 있어서의 그 전망을 논하고져 한다.을 논하고져 한다.

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화상처리를 응용한 단섬유 강화 고분자 재료내의 섬유배향 결정에 관한 연구

  • 이용훈;윤재륜
    • Proceedings of the Korean Fiber Society Conference
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    • 1998.10a
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    • pp.311-315
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    • 1998
  • 고분자 재료의 섬유 배향 상태는 각종 물성치의 지표가 되는 가장 기본적인 인자이므로 섬유 배향각 분포의 측진법을 확립하여 섬유 배향 상태를 밝혀두는 것은 재료 설계, 성형조건의 결정, 성형품의 역학적 특성 둥을 예측하는데 있어서 매우 중요하다. (중략)

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Properties and defects of Mn-Zn Ferrite single crystals grown by the modified process (연속 성장법으로 성장된 Mn-Zn Ferrite 단결정 특성 및 결함)

  • 정재우;오근호
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.1 no.2
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    • pp.23-33
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    • 1991
  • Mn - Zn Ferrite has the natural characteristics of incongruent melting and the zinc oxide evaporation while the crystal is being grown. As a result of these, it comes into existence to be a non-uniform distribution of cations along the crystal growth axis and also Pt particles are usually precipitated into the crystals in Bridgman method since the melt zone is maintained for a long time in the crucible. These have bad effects on the magnetic properties of ferrites. But, to overcome these faults and then acquire the better single crystals. new modified growth method was developed and the growth factors were investigated as following: melt height in the crucible, surface tension and density of melt, the behavior of melt at interface, the shapes of crucible and solid -liquid interface, powder feeding rate, and the crystal growing speed. In additon, when we analyzed the compositional fluctuations of grown crystals, they were supressed within 1.5 mol% $Fe_20_3$, 2 mol% MnO, ZnO respectively with comparing to initial composition of crystal and the microstructures of crystals on the(110) plane were observed by optical microscope through the chemical etching technique and the magnetic properties were determined.

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Build up decision making system for management and environment accompany change the environment police (환경정책변화에 따른 경영 및 환경 의사결정체계 구축)

  • Chun Jin-Ku;Kim Byeong-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.4 no.3 s.15
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    • pp.112-118
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    • 2003
  • This study aims to management and environmental system is a set of a theory logic management tools and principles designed to create the administrative procedures that a company needs to integrate management and environmental concerns into its daily business practices. Integrate environmental considerations of risk reduction and wise resource management into daily business decision making that includes performance and cost. Seek management and environmental solutions that promote competitiveness environmental aspect recognize need for a commitment to continuous improvement of a it's decision making model. Provide business with tools and methodologies to make better environmental choices and understand the environmental effects of resource flows. A last of understand use of the Decision Making element principal as a guideline for evaluating and ranking approaches. The result of this study are summarized as follows; (1) setting for approach decision management select of the change environment police, (2) making improvements of developing operational controls setting targets, (3) measuring and achieving success of EMS, (4) decision making system on the Environment and Management

Removal of ${\alpha}$-Gal Epitopes in Aortic Valve and Pericardium of Pig Using Green Coffee Bean ${\alpha}$-Galactosidase (돼지의 대동맥 판막 및 심낭에서 녹색콩 알파-갈락토시다아제를 이용한 알파-갈 항원결정인자 제거)

  • Park, Seong-Sik;Kim, Woong-Han;Kim, Kyung-Hwan;Lee, Chang-Ha;Choi, Sun-Young;Lee, Cheul;Oh, Sam-Sae;Kim, Kwan-Chang;Kim, Yong-Jin
    • Journal of Chest Surgery
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    • v.41 no.1
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    • pp.12-24
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    • 2008
  • Background: It is currently thought that tissue valve degeneration is related to an animal's immune response, which is mainly due to cell surface ${\alpha}$-Gal epitopes. Cell surface ${\alpha}$-Gal epitopes are known to be degraded by the enzyme called green coffee bean ${\alpha}$-Galactosidase. It is also well known that ${\alpha}$-Gal epitopes are immunologically stained by Griffonia Simplicifolia isolectin type B4. We know that many commercially available tissue valves are made of aortic valves and pericardial tissue of pig. So, we investigated whether ${\alpha}$-Gal epitopes of the aortic valve and pericardial tissue of a pig can be removed by green coffee bean ${\alpha}$-Galactosidase, and we did so by comparing immunologic staining of the tissues before and after the enzyme treatment. Material and method: After treating fresh porcine aortic valve and pericardial tissue with green coffee bean ${\alpha}$-Galactosidase at concentrations of 0.5 unit/mL, 1.0 unit/mL, 2.0 unit/mL, respectively, under the condition of pH 6.5, temperature. $4^{\circ}C$ and 24 hours of incubation, each sample was stained with Griffonia Simplicifolia isolectin type B4 immunpfluorescent labeling. We then examined whether the ${\alpha}$-Gal epitopes were reduced or abolished in each consecutive. concentration of green coffee bean ${\alpha}$-Galactosidase by comparing the degree of the Griffonia Simplicifolia isolectin B4 staining in each sample. Result: In the pig aortic valve tissue, a 1.0 unit/mL concentration of green coffee bean ${\alpha}$-Galactosidase at pH 6.5, $4^{\circ}C$ and reaction for 24 hours was enough for complete removal of ${\alpha}$-Gal epitopes from the cell sur face on the immunostaining with Griffonia Simplicifolia isolectin B4. On the other hand, more ${\alpha}$-Gal epitopes were present in the pig pericardial tissue on Griffonia Simplicifolia isolectin B4 staining before the enzyme treatment, and 1.0 unit/mL of galactosidase was not sufficient for complete removal of ${\alpha}$-Gal from the tissue. 2.0 units/mL of green coffee bean ${\alpha}$-Galactosidase was needed to completely remove the ${\alpha}$-Gal epitopes from the pericardial tissue on immunostaining. Conclusion: The ${\alpha}$-Gal epitopes of the pig's aortic valve and pericardial tissue were successfully stained with Griffonia Simplicifolia isolectin B4. We could remove nearly all the ${\alpha}$-Gal epitopes using green coffee bean ${\alpha}$-Galactosidase at the concentration of 1.0 unit/mL in the aortic valve. Of pig, and 2.0 unit/mL was need to nearly completely remove all the ${\alpha}$-Gal epitopes in the pericardial tissue of pig under the condition of pH 6.5, $4^{\circ}C$ and 24 hours of reaction time. In the near future, removal of ${\alpha}$-Gal epitapes in the pig's aortic valve and pericardial tissue will become a powerful tool for the improvement of the tissue valve durability. It needs to be determined if ${\alpha}$-galactosidase treated pig tissue is immune to human anti-Gal antibody or anit-Gal mooclonal antibodies.

A Study on the Land Suitability Analysis Based on Site Selection Variables using Macro Language (매크로 언어를 이용한 입지인자 변수조정에 따른 토지적합성 분석에 관한 연구)

  • Yi, Gi-Chul
    • Journal of the Korean Association of Geographic Information Studies
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    • v.6 no.1
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    • pp.59-77
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    • 2003
  • This study is to validate the use of macro language for the land suitability analysis aiming to help to resolve land use conflicts. The silver-town suitability analysis is conducted on the Geejang Gun, Busan Metropolitan city. Such digital maps as terrain, road, facility, and water body were created for various cartographic models. A cartographic model identified the best suitable areas for silver-town development based on the such site selection variables as a distance to facility and road, slope and aspect of terrain, land use etc. Then, the other cartographic model identified the most favorable site among the candidate sites based on the comparison of the aspect of proximity, usage and environmental quality. Macro language was used for these modeling process and was used for the manipulation of all these spatial variables used in the models to resolve land use conflicts relating to the decision making process of the final site selection. This study will improve the effectiveness and rationality of the traditional site suitability analysis.

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