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Analysis of Thyroid Nodule Prevalence and Related Factors in Adult Men and Women (성인 남녀에서 갑상선결절 유병률과 관련 인자 분석)

  • Ye-Eun Oh;Jung-Hoon Kim;Sung-Hee Yang
    • Journal of the Korean Society of Radiology
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    • v.18 no.4
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    • pp.373-381
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    • 2024
  • This study aimed to identify and assess the influence of risk factors on the frequency of thyroid nodules diagnosed through ultrasonography among adults visiting for health screenings. The study analyzed 210 adult men and women who underwent thyroid ultrasound at J Hospital in Busan. The differences in variables were analyzed using Chi-square and independent t-tests, and risk ratios were calculated using binary logistic regression. The results showed significant differences in gender, age, T3, Free T4, Uric acid, T-chol, HDL-C and LDL-C. The risk ratios for risk factors indicated that women had a 2.42 times higher risk compared to men, and the age groups 41-50 and over 61 had risks 2.32 and 2.22 times higher, respectively compared to those under 40. Conversely, and increase in T3 and Free T4 levels was associated with a decreased risk of 0.12 and 0.86 times, respectively, while lipid levels had negligible influence. Based on these findings, it is concluded that regular ultrasonography monitoring, rather than solely relying on biochemical markers, is crucial for the early detection and management of thyroid nodules.

Connectivity Analysis of the Tourism Resources in Jeju-do (제주특별자치도 관광자원의 연결성 분석)

  • Kim, Won-Jin
    • Journal of the Speleological Society of Korea
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    • no.81
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    • pp.79-81
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    • 2007
  • 제주특별자치도는 총면적 1,845km2로서 국토전체의 2%에 불과하나 고유한 전통문화와 이국적이며 아름다운 자연환경을 갖고 있는 우리나라의 대표적인 관광지이다. 최근에는 각종 국제행사를 유치함으로써 국내관광객 뿐만 아니라 외래 관광객도 흡입하는 국제적인 관광지로 인식되고 있다. 본 연구는 제주도에 분포하고 있는 개방형 용암동굴과 관광자원과의 연계성을 파악하고 네트워크 구조분석을 통하여 접근성과 연결성을 분석하고자 한다. 이러한 연구결과는 도로망에 따른 관광객의 이동성에 대한 관광개발계획에 시사점을 제공할 수 있다.

Effect of Patient Size on Image Quality and Dose Reduction after Added Filtration in Digital Chest Tomosynthesis (부가필터를 적용한 디지털 흉부단층합성검사에서 환자 체형에 따른 화질 평가와 선량감소 효과)

  • Bok, Geun-Seong;Kim, Sang-Hyun
    • Journal of the Korean Society of Radiology
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    • v.12 no.1
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    • pp.23-30
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    • 2018
  • To evaluate the effect of patient size on effective dose and image quality for Digital Chest Tomosynthesis(DTS) using additional 0.3 mm copper filtration. Eighty artificial nodules were placed in the thorax phantom("Lungman," Kyoto Kagaku, Japan), and Digital Chest Tomosynthesis(DTS) images of the phantom were acquired both with and without added 0.3 mm Cu filtration. To simulate patients of three sizes: small, average size and oversize, one or two 20-mm-thick layer of PMMA(polymethyl methacrylatek) blocks were placed on the phantom. The Effective dose was calculated using Monte Carlo simulations. Two evaluations of image quality methods have been employed. Three readers counted the number of nodules detected in the lung, and the measured contrast-to-noise ratios(CNRs) were used. Data were analyzed statistically. The ED reduced $26{\mu}Sv$ in a phantom, $33{\mu}Sv$ in one 20-mm-thick layer of PMMA block placed on the phantom, and $48{\mu}Sv$ in two 20-mm-thick layer of PMMA blocks placed on the phantom. The Effective dose(ED) differences between DTS with and without filtration were significant(p<0.05). In particular, when we used two 20-mm-thick layer of PMMA blocks placed on the phantom, the ED was significantly reduced by 36% compared with those without additional filtration. Nodule detection sensitivities were not different between with and without added filtration. Differences of CNRs were statistically insignificant(p>0.05). Use of additional filtration allows a considerable dose reduction during Digital Chest Tomosynthesis(DTS) without loss of image quality. In particular, additional filtration showed outstanding result for effective dose reduction on two 20-mm-thick layer of PMMA blocks placed on the phantom. It applies to overweight patients.

Three Cases of Mucocutaneous Angiomyolipoma in the Head and Neck Region with Reference to the HMB-45 and Melan-A Immunohistochemistry (두경부에서 발생한 점막피부 혈관근육지방종 3예 : HMB-45와 Melan-A에 대한 면역화학검사 특징)

  • Kim, Na-Rae;Kim, Dong-Young;Cha, Heung-Eog;Ha, Seung-Yeon
    • Korean Journal of Head & Neck Oncology
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    • v.25 no.2
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    • pp.150-152
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    • 2009
  • 혈관근육지방종은 지방, 평활근, 두꺼운 벽의 혈관이 다양한 비율로 구성된 흔하지 않은 과오종이며, 이는 결정 경화증을 동반하거나 산발적으로 발생한다. 저자들은 혈관근육지방종이 드물게 발생하는 두경부에서 발생한 귓바퀴 1예, 구개점막 2예의 혈관근육지방종을 보고하고자 한다. 병리소견상, 3예 모두에서 성숙지방조직, 불규칙한 혈관, 그리고 HMB-45와 Melan-A에 음성을 보이는 평활근육세포로 이루어진 조직소견을 보였으며, 여러군데에서 림프구 침윤이 3예 모두에서 관찰되었다. 점막피부 혈관근육지방종으로 진단하였다. 세증례 모두 결절경화증은 동반되지 않았다. 점막피부 혈관근육지방종에서는 혈관주변세포가 HMB-45와 Melan-A에서 음성을 보였으며, 이는 간이나 신장의 혈관근육지방종에서의 특징적인 양성반응과는 다른 점이었다. 간이나 신장에서 생긴 혈관근육지방종과 다른 임상병리적 특징을 비교 기술하고자 두경부에서 발생한 점막피부 혈관근육지방종 3예를 보고한다.

Clinicostatistical Analysis for 53 Cases which were performed Microlaryngeal Surgery under Suspension Laryngoscope (Suspension Laryngoscope 하에 후두미세 수술을 시행한 53명에 대한 임상통계학적 고찰)

  • 전하동;최인환;추광철;김선곤
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1979.05a
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    • pp.6.3-7
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    • 1979
  • During last two. decades, microlaryngeal surgery opened now era in the laryngeal surgery. In 1960, using Lynch's suspension laryngoscope, Seal co et al performed the first successful microsurgery in the treatment of polyp and other laryngeal diseases. In 1968, Kleinsasser reported a new technique of microlaryngeal surgery with a self retaining laryngoscope. Authors studied the statistic analysis of 53 cases (75 times) of the suspension laryngoscopic microsurgery at E.N.T. department of Han Yang University Hospital from May 1972 to April 1979 an reported this result. 1) sex distribution was male 1.3 : female 1. 2) age distribution was 3rd decade 14 cases (26.4%), 2nd decade 10 cases (18.7%) and 5th decade 9 cases (17%) in order. 3) chief compliant was hoarseness 48 cases (90.6%), dyspnea 16 cases (30.5%) and sore throat 8 cases (15.1%) in order. 4) diagnostic impression was polyp 18 cases (34%), nodule 12 cases (22.6%), papilloma 9 cases (17%), tumor 7 cases (13.2%), intubation granuloma 3 cases (5.7%) in order and other kinds were laryngeal stenosis with decannulation difficulty, laryngeal paralysis and hematoma. 5) histopathologic result of 48 cases was polyp 17 cases (35.4%), papilloma 11 cases (23%), nodule 9 cases (18.9%), malignancy 3 cases (6.3%), chronic inflammation 2 cases (4.2%) in order and others were hyperkeratosis, mucous retension cyst, nodule associated abscess, granuloma, hematoma and unconfirmed case. 6) in involved site, both sides 15 cases (60%), Lt.side 5 cases (19%), Rt side 3 cases (12%), anterior commissure 3 cases (12%) on the nodule and polyp (26 cases) and whole laryngeal involvement 7 cases (63.6%), one side cord involement 3 cases (23.7%), extralaryngeal involvement 1 cases (9.1%) on the papilloma (11 cases).

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Image Analysis of Computer Aided Diagnosis using Gray Level Co-occurrence Matrix in the Ultrasonography for Benign Prostate Hyperplasia (전립선비대증 초음파 영상에서 GLCM을 이용한 컴퓨터보조진단의 영상분석)

  • Cho, Jin-Young;Kim, Chang-Soo;Kang, Se-Sik;Ko, Seong-Jin;Ye, Soo-Young
    • The Journal of the Korea Contents Association
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    • v.15 no.3
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    • pp.184-191
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    • 2015
  • Prostate ultrasound is used to diagnose prostate cancer, BPH, prostatitis and biopsy of prostate cancer to determine the size of prostate. BPH is one of the common disease in elderly men. Prostate is divided into 4 blocks, peripheral zone, central zone, transition zone, anterior fibromuscular stroma. BPH is histologically transition zone urethra accompanying excessive nodular hyperplasia causes a lower urinary tract symptoms(LUTS) caused by urethral closure as causing the hyperplastic nodule characterized finding progressive ambient. Therefore, in this study normal transition zone image for hyperplasia prostate and normal transition zone image is analyzed quantitatively using a computer algorithm. We applied texture features of GLCM to set normal tissue 60 cases and BPH tissue 60cases setting analysis area $50{\times}50pixels$ which was analyzed by comparing the six parameters for each partial image. Consequently, Disease recognition detection efficiency of Autocorrelation, Cluster prominence, entropy, Sum average, parameter were high as 92~98%.This could be confirmed by quantitative image analysis to nodular hyperplasia change transition zone of the prostate. This is expected secondary means to diagnose BPH and the data base will be considered in various prostate examination.

CLINICO-STATISTICAL STUDY OF PATIENTS WITH HOARSENESS (사성환자의 임상통계적 관찰)

  • 문영일;박연아;김영주;조은아
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1987.05a
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    • pp.15.2-16
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    • 1987
  • 사성이란 후두의 발생기능에 장애가 있을 때 생기는 후두질환의 가장 대표적인 주증상으로 인간 문화의 발달에 병행되어서 대화에 의한 전달수단이 중요시되고 또한 암에 대한 인식이 높아져 사성을 호소하는 환자들이 많아지는 경향이 있다. 이에 저자는 1980년 1월부터 1984년 12월까지 이화여자대학교 의과대학 부속병원 이비인후과 외래에 내원한 신외래환자 총 24,949명 중 사성을 주소로 한 800명의 환자에 대하여 병력지를 기준하여 각 질환을 통계적으로 분석 검토하여 다음과 같은 성적을 얻었다. 1) 이비인후과 외래환자 총 24,949명중 사성환자는 800명으로 약 3.2%이었다. 2) 외래사성환자 800명중 남자 336명, 여자 464명으로 남녀비는 약 1 : 1.4이었다. 3) 질환별로는 급성 후두염 248예(31.0%), 만성 후두염 186예(23.3%), 성대결절 160예(20.0%), 성대폴립 90예(11.3%), 성대마비 56예(7.0%), 후두 유두종 12예(1.5%), 후두암 9예(1.1%)이었다. 4) 연령별로는 30대가 213예(26.6%), 20대가 190예(23.8%), 40대가 179예(22.4%)의 순이었다. 5) 각 질환별 최다연령은 급성 후두염 30대 73예(29.4%), 만성 후두염 30대 53예(28.5%), 성대결절 30대 52예(32.5%), 성대폴립 40대 26예(28.9%), 성대마비 40대 14예(25.0%), 후두암 50대 6예(66.7%)이었다. 6) 발병부터 초진까지의 기간은 10일 이내가 153예(19.1%)로 제일 많았고 1개월∼3개월 138예(17.3%), 11일∼l개월 119예(14.9%)의 순이었다. 7) 각 질환에 따른 발병부터 초진까지의 기간의 최다분포는 급성 후두염은 10일 이내가 117예(47.2%), 만성 후두염은 3개월∼6개월이 44예(23.7%), 성대결절은 3개월∼6개월이 40예(25.0%), 성대폴립은 6개월∼1년이 20예(22.2%), 성대마비는 10일이내가 12예(21.4%)이었다. 8) 질환별 동반증상 분포는 사성만을 호소한 경우가 394예(41.4%)로 가장 많았고 동반증상으로는 인두통, 이물감, 객담, 기침, 연하장애, 호흡곤란의 순이었다. 9) 저자의 연도별 사성환자의 평균발생빈도(3.2%)를 문(1981)의 1975년 1월부터 1979년 12월(만 5년간)까지의 평균발생빈도(2.9%)와 비교할 때 증가하였다.

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Evaluation of Diagnostic Usefulness of Thyroid Lesions of Deep Learning-based CAD System (딥러닝을 기반으로 한 CAD 시스템의 갑상샘 질환의 진단 유용성)

  • Chae Won Kang;Hyo Yeong Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.5
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    • pp.551-556
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    • 2024
  • This study aims to evaluate the diagnostic concordance and accuracy by comparing thyroid lesions diagnosed with the artificial intelligence-based computer-aided diagnosis (CAD) system, S-DetectTM, to the results of fine-needle aspiration biopsy(FNAB). A retrospective study was conducted involving 60 patients at N Hospital in Gyeongnam from May 2023 to September 2023. The study used S-DetectTM to analyze ultrasound findings and malignancy risk of thyroid nodules and compared these findings with FNAB results to determine accuracy. The study assessed the sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of S-DetectTM and evaluated the diagnostic concordance between the two methods using Kappa analysis. S-DetectTM demonstrated a sensitivity of 90.5%, specificity of 83.2%, accuracy of 88.3%, PPV of 80.7%, and NPV of 92.7%. The Kappa value for diagnostic agreement between S-DetectTM and FN AB was 0.719 (p<0.05), indicating a high level of agreement between the methods. Therefore, the CAD system S-DetectTM proves valuable in distinguishing between malignant and benign thyroid lesions and could reduce unnecessary tissue examinations when used appropriately before thyroid fine-needle aspiration.

Evaluation of the Usefulness of Differential Diagnosis of Breast Mass using Elasticity Score and Elasticity Ratio in Elastography (탄성초음파에서 유방종괴의 감별진단을 위한 탄성도 점수와 변형비의 유용성 평가)

  • An, Hyun;Im, In-Chul;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.12 no.5
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    • pp.677-682
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    • 2018
  • This study evaluated the usefulness of the elasticity score and elasticity ratio in the differential diagnosis of benign and malignant lesion in breast elastography. We performed a retrospective analysis based on the results of core needle biopsy histology. The Mann-Whitney U test was used to confirm the difference between the 5-degree elasticity score and the Fisher's Exact test. ROC curve analysis was used to determine the elasticity score and the best cut-off value of the elasticity ratio for the prediction of malignant lesions. There was a statistically significant difference (p= .000) between the homogeneity of the elasticity score and the difference of the elasticity ratio between the benign and malignant lesion groups. On the ROC curve analysis, the elasticity score and the elasticity ratio for predicting benign and malignant lesion were determined as AUC 0.806, 0.824, cut-off value 3, 4.4 (p= .001). Therefore, the elasticity score and elasticity ratio may be useful in the differential diagnosis of breast mass.

Automated Detection and Volume Calculation of Nodular Lung Cancer on CT Scans (CT 영상에서 결절성 폐암의 자동추출 및 체적계산)

  • Kim, Do-Yeon;Kim, Jin-Hwan;Noh, Seung-Moo;Park, Jong-Won
    • Journal of KIISE:Computing Practices and Letters
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    • v.7 no.5
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    • pp.451-457
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    • 2001
  • This paper describes automated methods for the detection of lung nodules and their volume calculation on CT scans. Gray-level threshold methods were used to segment the thorax from the background and then the lung parenchymes from the thoracic wall and mediastinum. A scanning-ball algorithm was applied to more accurately delineate the lung boundaries, thereby incorporating peripheral nodules contiguous to pleural surface within the segmented lung parenchymes. The lesions which have the high gray value were extracted from the segmented lung parenchymes. The selected lesions include nodules, blood vessels and partial volume effects. The discriminating features such as size, solid-shape, average, standard deviation and correlation coefficient of selected lesions were used to distinguish true nodules from pseudo-lesions. Volume and circularity calculation were performed for each identified nodules. The identified nodules were sorted in descending order of the volume. These method were applied to 621 image slices of 19 cases. The sensitivity was 95% and there was no false-positive result.

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