• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.13 no.1
• /
• pp.7-22
• /
• 2010

Purpose: Nodular gastritis is a characteristic finding of Helicobacter pylori infection in children. The aim of this study was to evaluate the difference in gene expression in the gastric mucosa of H. pylori-infected and non-infected children, and to analyze the difference in gene expression using cDNA microarray analysis of nodular gastritis caused by H. pylori infection. Methods: Twelve children (6 boys and 6 girls; mean age 9.8 years) who underwent upper gastrointestinal endoscopy and biopsy at Seoul National University Bundang Hospital were included in the study. The subjects were divided into three groups according to the presence of H. pylori infection and nodular gastritis on endoscopic examination. Gastric mucosa tissue was kept at $-70^{\circ}C$ and RNA was extracted to perform cDNA microarray analysis in each patient. Results: cDNA microarray analysis in children revealed a clear distinction between H. pylori-infected and non-infected gastric mucosa. Specifically, 182 over-expressed genes and 29 under-expressed genes were identified in H. pylori-infected gastric mucosa compared to non-infected mucosa. H. pylori-infected nodular gastritis revealed different gene expression patterns from H. pylori-infected normal gastric mucosa; five genes were over-expressed and five genes were under-expressed. Conclusion: In the presence of H. pylori infection, gastric mucosa shows distinct differences in gene expression, and nodular gastritis with H. pylori infection in children may be associated with over- or under-expression of some genes. Further studies are required to clarify the host response and the pathogenesis of nodular gastritis in children.

• Journal of Korean Foot and Ankle Society
• /
• v.8 no.1
• /
• pp.97-100
• /
• 2004

Purpose: To evaluate the results of surgical treatment and relationship between the recurrence and characteristics of ganglions in foot and ankle. Materials and Methods: Seventeen cases of ganglions located in foot and ankle, excised at St. Benedict Hospital from Mar. 1993 to Apr. 2003, were included in the study. All of cases were analyzed retrospectively in terms of age, sex of the patients, location and size of the ganglion, symptom, operative method as well as recurrence rate were evaluated. The mean follow up was 1.8 years (11 months${\sim}$6.5 years). Results: The size of ganglion ranged from 0.5 cm to 5.0 cm with mean size of 2.5 cm. The most common area of ganglion was the dorsum of foot and pain was the primary chief complain. The recurrence was found in 4 cases (23.5%): 1 of them occurred among 8 cases the diameter of which was less than 2.5 cm and other 3 occurred among 9 cases larger than 2.5 cm. 12 cases were completely excised mass with no recurrence. But 5 cases were incompletely excised & ligated stalk of mass and 4 cases of them were recurred. A correlation was only observed between complete excision and low recurrence rate. Conclusion: Recurrence rate of ganglions in foot and ankle was high and the correlation was obtained between complete excision and low recurrence rate.

• Journal of Veterinary Clinics
• /
• v.27 no.5
• /
• pp.569-572
• /
• 2010

A 4-year-old neutered female Pekingese dog (weighing 3.6 kg) was referred with the primary complaint of exercise intolerance with occasional syncope. Physical examination revealed irregularly irregular heart rhythm with persistent pulse deficits. The 12-lead surface ECG showed a marked sinus arrest with occasional junctional escape beats, indicating a sick sinus syndrome. Permanent transvenous cardiac pacing with a rate-responsive bipolar implantable pacemaker (VVIR type) was performed in the right ventricle. After pacemaker implantation, the clinical signs were remarkably improved. No further syncopal episodes have yet been occurred after implantation.

• The Journal of the Korean dental association
• /
• v.24 no.2 s.201
• /
• pp.183-189
• /
• 1986

우측 측두악관절에 동통과 연발음을 수반한 개구장애 및 저작장애를 호소하는 환자에 있어서 측두 악관절조영술을 하므로써 관절원판부의 천공과 관절원판의 전방전위의 악관절내장증으로 진단하였으며, 악관절원판부의 성형술과 측두악관절 결절의 절제술을 시행하였다. 수술후 8주부터 최대개구가 4.5cm이였으며 측두악관절의 원활한 운동으로 별 불편없이 저작 및 개구운동이 가능하게 되었다.

• The Journal of the Korean bone and joint tumor society
• /
• v.7 no.2
• /
• pp.64-67
• /
• 2001

Epithelioid sarcoma has been well characterized as a distincitve entity. In the classic form, it occurs in the distal extremities of young adults. However, in the proximal form, it was found mostly in the pelvis, perineum, and genital tract of young to middle-aged adults. Morphologically, the tumor cells had promient epithelioid or rhabdoid features with marked cytologic atypia, and grew in a multinodular pattern. Immunohistochemically, cytokeratin, epithelial membrane antigen, and vimentin were positive in the tumor cells. This reports dealt with 32-year-old male lesion on his perineum. The tumor shows typical features of proximal type epithelioid sarcoma. We also discussed pathological differential diagnosis and prognosis on this particular disease.

• Restorative Dentistry and Endodontics
• /
• v.36 no.3
• /
• pp.238-242
• /
• 2011

Objectives: Palatogingival groove is a developmental anomaly that starts near the cingulum of the tooth and runs down the cementoenamel junction in apical direction, terminating at various depths along the roots. While frequently associated with periodontal pockets and bone loss, pulpal necrosis of these teeth may precipitate a combined endodontic-periodontal lesion. This case presents a case of a lateral incisor anatomically complicated with palatogingival groove. Methods: Two patients with lesion associated with the palatogingival groove were chosen for this report. Palatogingival grooves were treated with different restoration materials with endodontic treatment. Conclusions: Maxillary lateral incisor with a palatogingival groove may occur the periodontal disease with pulpal involvement. Elimination of groove may facilitate the periodontal re-attachment and prevent the recurrence.

• Journal of the Korean Arthroscopy Society
• /
• v.4 no.1
• /
• pp.67-70
• /
• 2000

Osgood-Schlatter's disease is generally treated conservatively. However, surgical treatment is necessary for some patients with recurrent or persistent pain that does not respond to conservative treatment. Most authors recommend the excision of the loose ossicles present around the distal end of the patellar tendon. The authors report the technique of arthroscopic removal of the ossicles for Osgood-Schaltter's disease instead of the conventional technique through the incision at the tibial tuberosity. The advantages of this technique are less damage to the patellar tendon, early postoperative recovery, making no incisional scar in front of the tuberosity which causes the scar discomfort in kneeling, and more cosmetic result.

• Journal of rehabilitation welfare engineering & assistive technology
• /
• v.10 no.1
• /
• pp.87-92
• /
• 2016

In this paper, we improved classification performance of benign and malignant lung nodules by including the parenchyma features. For small pulmonary nodules (4-10mm) nodules, there are a limited number of CT data voxels within the solid tumor, making them difficult to process through traditional CAD(computer aided diagnosis) tools. Increasing feature extraction to include the surrounding parenchyma will increase the CT voxel set for analysis in these very small pulmonary nodule cases and likely improve diagnostic performance while keeping the CAD tool flexible to scanner model and parameters. In AdaBoost learning using naive Bayes and SVM weak classifier, a number of significant features were selected from 304 features. The results from the COPDGene test yielded an accuracy, sensitivity and specificity of 100%. Therefore proposed method can be used for the computer aided diagnosis effectively.

• The Korean Journal of Zoology
• /
• v.32 no.3
• /
• pp.211-220
• /
• 1989

The fine structure of the aggregate glands-one of the capture thread producing organs-in the orb web spider, Nephila clavata L.Koch, is studied with light and electron microscopes. Gluey capture threads or sticky spirals of the orb web are originated from the silks of two flagelliform glands and four aggregate glands which are connected to the posterior spinnerets, and the arrangement fo their spigots(large spinning tubes) shows a charaterstic form called "triad". The aggregate galnd is composed of large and multilobed secretory portion and thick excretory duct surrounded by large irregular nodules. The excretory duct of the aggregate galnds basically consists of three superposed types of cells which are inner columnar epithelium, nodule-forming cells and outer connestives. The cuticles of the proximal duct near the secretory portion are composed of endocuticle and exocuticle, whereas ghe distal duct near the spinning tubes has a electron lucent subcuticle which had the functions of water removal and orientation of silk fibers. In the cytoplasmic process of the large and irregular nodule-forming cells surrounded by invaginations of the plasma membranes, numerous mitochondria and glycogen particles are contained. The maturational level of the nodule cells is perceived from the appearence of these cell inclusions. The secretory portion of the glands which porduce the secretory silk material shows two layers of the cells which are simple cuboidal epithelium and several connective layers. In the cytoplasm of the glandular epithelial cell, rough endoplasmic reticulums are well developed, and two types of secretory granules are observed. Between the adjacent epithelial cells, specialized septate junctions are formed along the plasma membranes.membranes.

• Tuberculosis and Respiratory Diseases
• /
• v.65 no.4
• /
• pp.339-342
• /
• 2008

Early CT findings of transient radiographic progression (TRP) during treatment of active pulmonary tuberculosis including subpleural, interlobular or intralobular septal thickening and micronodules are shown in the present case. Late CT findings of TRP are subpleural, enhancing nodular infiltration with internal low attenuation. These CT features accompanied by a lack of clinical worsening in young patients taking antituberculous medication due to pulmonary tuberculosis can help to differentiate TRP from other disease entities.