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Transcatheter Closure of Patent Ductus Arteriosus with a Amplatzer$^{(R)}$ Vascular Plug in Two Dogs (개에서 Amplatzer$^{(R)}$ vascular plug를 이용한 동맥관개존증의 폐쇄 2 증례)

  • Kang, Min-Hee;Kim, Jung-hyun;Moon, So-Jeung;Kim, Seung-gon;Yeo, Jung-Jin;Lee, Chang-Min;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.28 no.6
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    • pp.591-594
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    • 2011
  • A 9-month-old, intact female Maltese dog and one-year-old, intact female beagle dog were presented with continuous heart murmur. These 2 dogs were diagnosed as patent ductus arteriosus (PDA) based on the two-dimensional echocardiography and angiography. Due to the large shunt size, commercially available ductal occlude device was used for transcatheter occlusion of PDA. After Amplatzer$^{(R)}$ vascular plug placement, cardiac murmur was abruptly disappeared in Maltese dog and mildly decreased in beagle dog. Complications and safety after the procedure were evaluated regularly in these 2 dogs. This is first clinical application of Amplatzer$^{(R)}$ vascular plug for transcatheter closure of PDA in two dogs in Korea.

Algorithm and Performance Evaluation of High-speed Distinction for Condition Recognition of Defective Nut (불량 너트의 상태인식을 위한 고속 판별 알고리즘 및 성능평가)

  • Park, Tae-Jin;Lee, Un-Seon;Lee, Sang-Hee;Park, Man-Gon
    • Journal of Korea Multimedia Society
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    • v.14 no.7
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    • pp.895-904
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    • 2011
  • In welding machine that executes existing spot welding, wrong operation of system has often occurs because of their mechanical motion that can be caused by a number of supply like the welding object. In exposed working environment for various situations such as worker or related equipment moving into any place that we are unable to exactly distinguish between good and not condition of nut. Also, in case of defective welding of nut, it needs various evaluation and analysis through image processing because the problem that worker should be inspected every single manually. Therefore in this paper, if the object was not stabilization state correctly, we have purpose to algorithm implementation that it is to reduce the analysis time and exact recognition as to improve system of image processing. As this like, as image analysis for assessment whether it is good or not condition of nut, in his paper, implemented algorithms were suggested and list by group and that it showed the effectiveness through more than one experiment. As the result, recognition rate of normality and error according to the estimation time have been shown as 40%~94.6% and 60%~5.4% from classification 1 of group 1 to classification 11 of group 5, and that estimation time of minimum, maximum, and average have been shown as 1.7sec.~0.08sec., 3.6sec.~1.2sec., and 2.5sec.~0.1sec.

Assessment of Attenuation Correction Algorithms With a $^{137}$Cs Point Source (Cs-137 점선원을 이용한 감쇠보정기법들에 대한 평가)

  • Bong, Jung-Kyun;Kim, Hee-Joung;Park, Hae-Jung;Kwon, Yun-Youn;Son, Hye-Kyoung;Yun, Mi-Jin;Lee, Jong-Doo;Jung, Hae-Jo
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2004.11a
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    • pp.96-99
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    • 2004
  • The objective of this study is to assess attenuation correction algorithms utilized in a multipurpose whole-body GSO PET scanner. Four different types of phantoms were tested using different types of attenuation correction techniques. FOV (Field of View) of 256mm was used for brain PET imaging. For compensating attenuation, transmission data of a $^{137}$Cs point source were acquired after the F-18 emission source was infused to the phantoms. Scatter correction were peformed. Reconstructed images of the phantoms were assessed. In addition, reconstructed images of a normal subject were compared and assessed by nuclear medicine physicians. As a result, decreased intensity at the central portion of the attenuation map with cylindrical phantom was noticed during use of the measured attenuation correction. On the other hand, segmentation or remapping attenuation correction provided uniform phantom image. the images reconstructed from the clinical brain data explained the attenuation of a skull, at though reconstructed images of the phantoms couldn't explain it. in conclusion, the complicated and improved attenuation correction methods were required to obtain the better accuracy of the quantitative brain PET images. Our study will be useful in improving quantitative brain PET imaging modalities with attenuation correction of $^{137}$Cs transmission source.

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In Vivo Measurement of Extracellular Monoamines and Their Metabolites in the Rat Posterior Hypothalamus Using Microdialysis Technique (미세투석법을 이용하여 흰쥐 후 사상하부에서 세포외액의 모노아민과 대사체들의 생체내 측정)

  • Sung, Ki-Wug;Kim, Seong-Yun;Cho, Young-Jin;Lee, Kweon-Haeng;Lee, Sang-Bok
    • The Korean Journal of Pharmacology
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    • v.28 no.1
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    • pp.1-9
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    • 1992
  • Catecholamines, serotonin and their metabolites were measured in the posterior hypothalamus of urethane-anesthetized normotensive Wistar Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) using brain microdialysis which is a recently developed experimental method to measure the release of neurotransmitters and their metabolites at the localized brain area in vivo. Microdialysis probe was implanted stereotaxically to the rat posterior hypothalamus and perfused by Ringer's solution. Monoamines and their metabolites were quantified by reverse phase high performance liquid chromatography with electrochemical detection. In vitro recovery test of microdialysis showed that there exist inverse relationship between the perfusion flow rate and the relative recovery of neurochemical compounds. The estimated extracellular concentration of dopamine was about 32 nM, of norepinephrine 50 nM, of epinephrine 50 nM, of serotonin 73 nM, of 3, 4-dihydroxyphenylacetic acid (DOPAC) 281 nM, of homovanillic acid (HVA) 181 nM, and of 5-hydroxyindoleacetic acid (5HIAA) 3767 nM in the hypothalamic perfusate of the normotensive rat. There was no difference in the basal level of monoamines between the SHR and the WKY. In contrast, the level of DOPAC, HVA and 5HIAA in SHR was higher than that in the WKY, This study demonstrated that the microdialysis technique should be an applicable tool for in vivo measurement of central neurochemical substances.

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Comparison of Stereoscopic Fusional Area between People with Good and Poor Stereo Acuity (입체 시력이 양호한 사람과 불량인 사람간의 입체시 융합 가능 영역 비교)

  • Kang, Hyungoo;Hong, Hyungki
    • Journal of Korean Ophthalmic Optics Society
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    • v.21 no.1
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    • pp.61-68
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    • 2016
  • Purpose: This study investigated differences in stereoscopic fusional area between those with good and poor stereo acuity in viewing stereoscopic displays. Methods: Stereo acuity of 39 participants (18 males and 21 females, $23.6{\pm}3.15years$) was measured with the random dot stereo butterfly method. Participants with stereo-blindness were not included. Stereoscopic fusional area was measured using stereoscopic stimulus by varying the amount of horizontal disparity in a stereoscopic 3D TV. Participants were divided into two groups of good and poor stereo acuity. Criterion for good stereo acuity was determined as less than 60 arc seconds. Measurements arising from the participants were statistically analyzed. Results: 26 participants were measured to have good stereo acuity and 13 participants poor stereo acuity. In case of the stereoscopic stimulus farther than the fixation point, threshold of horizontal disparity for those with poor stereo acuity were measured to be smaller than the threshold for those with good stereo acuity, with a statistically significant difference. On the other hand, there was no statistically significant difference between the two groups, in case of the stereoscopic stimulus nearer to the fixation point. Conclusions: In viewing stereoscopic displays, the boundary of stereoscopic fusional area for the poor stereo acuity group was smaller than the boundary of good stereo acuity group only for the range behind the display. Hence, in viewing stereoscopic displays, participants with poor stereo acuity would have more difficulty perceiving the fused image at farther distances compared to participants with good stereo acuity.

생강엑기스의 제조에 관한 연구

  • 신애자
    • Food Industry
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    • s.94
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    • pp.37-40
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    • 1988
  • 1) 본 연구에서 시료로 선정한 충남 서산산 건강(dry ginger)은 수분이 $9.4\%$, 회분이 $8.7\%$ 그리고 alcohol에 의한 추출량이 약 $9\%$이다. 이는 선진국에 채택사용하고 있는 건강의 규격기준에 의하면 양호하다. 2) Non- flavor물질의 추출을 최소화하고 특히 증류과정에서 유효성분 손실을 최소화 할 수 있고, 엑기스내의 용매 잔류량이 인체에 유해하지 않고 추출효율을 높일 수 있는 용매는 ethyl alcohol이다. 3) 널리 사용하고 있는 관류추출(percolation)의 성능을 분석하고 이의 개선방안을제시하였다. - 추출효율을 높이기 위하여 건강(dry ginger)의 입자를 작게하면 압력강하가 증대되어순환되는 용액의 유속을 제어하기가 힘들다. - 입자가 작을 시에는 유체의 흐름이chan-nelling현상을 나타낸다. - 위와 같은 조건에서는 물질 전달속도가 느리므로 추출효율을 증대시킬 수가 없다. - 따라서 percolation추출에 사용되는 건강의 입자크기는 30mesh크기 이상이어야 운전조작이 용이하나 추출효율이 낮으므로, 추출시간 6시간에 회수된 생강엑기스양은 약 $2.5\%$이다. 4) percolation추출의 단점을 보완하기 위하여 기계적교반 추출을 선택하여 다음과 같은 개선점을 찾았다. - 교반형 추출에서는 고 - 액분리시 cake 저항에서 문제가 야기되지 않는 범위까지 건강의 입자를 작게할 수 있으므로 추출효율을 크게 향상시킬 수 있었다. 즉, 작게 분쇄된 건강(30mesh통과$90\%$)을 대상으로 추출시간 3시간에 $7\%$의 회수율로 증대시켰다. 최적 운전조건은 다음과 같다. 건강시료:1kg 시료크기:-30mesh$90\%$ 용매:ethyl alcohol 3$\iota$ 교반속도:900r.p.m 추출온도:상온($15\~25^{\circ}C$) 추출시간:3시간 일차 추출조건과 동일하게 하여 얻어진 엑기스의 수율이 $2\~2.5\%$이므로 총엑기스의 수율은 건강(dry ginger)무게기준으로 $8.5\~9.5\%$이었다. 5) 교반추출의 효율이 개선되었다 하더라도 추출물의 분리가 용이하여야만 공정의 이용이 가능하다. 그러므로 교반추출후 고 - 액분리를 위하여 정압여과 장치를 이용하여 여과시 cake의 평균 비저항을 얻었으며, 이의 값은 $4.31\times10^8cm\;/\;gr$으로서 여과에는 어려움이 없다는 것을 의미한다. 따라서 추출속도와 효율이 상대적으로 우수한 교반형 추출기의 가능성을 예시할 수 있음을 알 수 있었다. 6) 추출물을 농축과정에서 휘발성 oil의 손실을 최대로 줄이기 위해서는 단순증류를 하지 말고 분별증류를 수행하여야 하며, gingerol과 같은 중요성분의 열분해 반응을 억제하기 위해서는 열전달 효율을 증대시켜 증류조작을 원활히 수행하여야 하므로, still내의 농축물을 계속 교반시켜야 하며 감압상태에서 증류온도는 $40\~50^{\circ}C$로 유지시키는 것이 가장 바람직하다. 7) Ethyl alcohol로 추출된 엑기스내의 수분이나 회분함량은 외국산 제품에 비하여 약간 낮고, 반면에 조지방 및 조단백 성분의 함량은 약간 높게 나타나고 있어 대체적으로 본 연구에서 얻어진 엑기스내의 비풍미성분(non- fla-vour component) 함량은 외국산에 비하여 많은 차이가 없다. 8) 수입 외국산에 비하여 국산엑기스(본 연구에서 ethyl alcohol로 추출)내의 무기성분등의 함량은 비교적 낮은 편이다. 9) 건강에서부터 oleoresin을 얻어 paradol을 제거시킨 후 순수한 gingerol을 분리하여 IR과 NMR로 확인한 결과, 국산건강의 엑기스에는 주로 6-gingerol이고 약간의 10-gingerol이 함유된 것으로 나타났다. 10) 순수하게 분리된 gingerol을 열분석(TGA와 DTG)한 결과 약 $75^{\circ}C$에서 gingerol의 열분해 반응이 일어남을 알수 있었다. 11) 건강 분말시료와 엑기스내의 미생물 검사 결과 건강분말에서는 세균수가 많이 존재하는 것으로 나타났으나, 이는 ethyl alcohol로 추출하는 공정 중 대부분의 균들이 사멸된 것으로 나타났다. 12) 관능적 측면에선, 본 연구에서 제조한 엑기스와 수입엑기스를 비교한 결과 생강 특유의 맛은 비슷했으나, 수입엑기스에서는 쓴맛과 톱밥냄새를 느낀다는 결과를 나타내었으며 전체적인 종합적 풍미는 국산 건강엑기스가 좋은 것으로 나타났다.

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Studies on the Processing of Powdered Katsuobushi and Its Flavor Constituents 3. Volatile Flavor Components of Powdered Katsuobushi (분말가쓰오부시의 제조 및 풍미성분에 관한 연구 3. 분말가쓰오부시의 향기성분)

  • OH Kwang-Soo;LEE Eung-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.22 no.4
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    • pp.169-176
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    • 1989
  • Volatile flavor components in powdered Katsuobushi were simultaneous trapped by steam distillation-extraction method, and these were fractionated into the neutral, the phenolic, the acidic and the basic fraction. Volatile flavor components in these fraction were analyzed by the high-resolution GC and GC-MS equipped with a fused silica capillary column. The whole steam volatile concentrate consisted of $48\%$ neutral fraction(NF), $35\%$ phenolic fraction(PF), $12\%$ acidic fraction(AF) and $5\%$ basic fraction(BF). Thirty components such as 8 hydrocarbons, 8 aldehydes, 6 furans, 5 alcohols and 3 ketones were identified from NF. And sixteen components such as phenol, guaiacol, dimethoxy phenol, eugenol in PF, twelve components such as propionic, butanoic, isopentanoic, n-hexanoic, heptanoic, octanoic acid in AF, ten components such as 2,6-dimethylpyrazine, 2-nethylpyridine, 2,4-dimethylthiaBole in BF were identified. NF and PF gave a much higher yield than others and were assumed to be indispensable for the reproduction of aroma of powdered Katsuobushi. It was also identified eight components of volatile carbonyl compounds such as ethanal, propanal, butanal, pentanal by 2,4-DNPH method.

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A Study on the Design Improvement to prevent the stoppage phenomenon of Launch Support Device for Self-Propelled Artillery (자주포용 발사지지대의 멈춤현상 방지를 위한 설계개선 연구)

  • Kim, Sung Hoon;Park, Young Min;Noh, Sang Wan;Park, Dae Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.443-450
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    • 2020
  • This paper reports a design improvement study to solve the stoppage phenomenon caused by the launch-support device applied to K105A1. The K105A1 is a weapon system equipped with an old 105 mm towed howitzer in a wheeled vehicle, which provides superior maneuverability compared to track equipment. The launch support device serves to withstand fire impact and load. In this way, this device is fixed firmly to the ground in preparation for the shooting mission and is responsible for the critical performance, such as fixing the position of the vehicle. On the other hand, during the field test, a temporary stoppage of the launch support occurred, which caused a problem of not being fixed to the ground. To solve this problem, the cause of failure was analyzed by a replay test and parts inspection. In addition, the operating concept, method, and design were analyzed to derive the cause and solve the problem by changing the parts design. Finally, the performance and firing missions were performed normally by applying the changed design to K105A1. The performance stability and reliability of the launch support device were confirmed, which are expected to be of great assistance in the development of military equipment in the future.

Evaluation of Image Quality using ATS-539 Phantom and SNR in the Ultrasonographic Equipment (ATS-539 다목적 팬텀과 SNR을 이용한 초음파 영상평가)

  • Kim, Min-Ju;Lee, Jin-Soo;Ko, Seong-Jin;Kang, Se-Sik;Kim, Jung-Hoon;Kim, Dong-Hyun;Kim, Changsoo
    • The Journal of the Korea Contents Association
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    • v.13 no.8
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    • pp.284-291
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    • 2013
  • The importance of ultrasound examination in the field of medical imaging has been emphasized and the interest in sonographic image evaluation is growing. However image evaluations by the non-standardized criteria and methods, so establishment of legal provisions and objective evaluation criteria are needed. In this study, we used SNR to find out more quantitative way and supplement the limitations of the existing phantom image evaluation. The results of acquired 8 images using ATS-539 multipurpose phantom were compared in SNR of sensitivity and gray-scale dynamic range. In the result of the experiment, excellent equipment of existing phantom images are G1, S1 and G2 in regular sequence. In SNR of sensitivity, G1, S1 and G2 and in SNR of gray-scale dynamic range, S1 G1 and G2 in order. In the conclusion, all the experiment results did not show big difference and regular pattern neither. Therefore, the new evaluation measures should be used with the existing phantom image evaluation method for more objective and quantitative evaluation of the ultrasound imaging device.

A comparison of bladder volume by sonogram and CBCT for Pelvic region cancer (골반부 암 치료 시 초음파검사를 통한 방광체적과 CBCT영상 방광체적의 비교)

  • Son, Seong Ho;Park, Ha Ryung;Baek, Jung Jin;Son, Jong Ki;Choi, Min Ho
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.2
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    • pp.7-12
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    • 2019
  • Purpose: During the pelvic radiation therapy, it is performed with controlling bladder volume because the range of irradiation is changed depending on the bladder volume. Therefore in this study, we evaluate the accuracy of BVI by tracing the change of bladder volume using ultrasonic pulse diagnosis equipment(BVI 6100, Medical supply Co. LTD) Material and Methods: From January 2017 to September 2018, 19 patients who received pelvic radiation therapy at Pusan National University Hospital were included. To treat the patient, we compared that the bladder volume obtained from the BVI and the bladder volume obtained from the CBCT image then we evaluated for significance. Results: There was a significant correlation of r=0.773, BVI and CBCT in the whole volume section. However, based on the bladder volume in the RTP Image the p value was shown to be 0 at 125~175cc and lower than 0.05 at 175~275cc, And more than 0.05 at 275~375cc. Conclusions: In this study, the patient whose bladder volume is above than 275cc, there is a significance of bladder volume between BVI and CBCT image. However, we could make a decision to be undermined the reliability of BVI measurement in the case of the patient with emptied his urine. Therefore, it is possible to acquire a significant value for 175~275cc patients to use the correction value of BVI and the appropriate tolerance of volume.