• Title/Summary/Keyword: 거대과학

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The Production, Distribution, and Utilization of Rice in Japan (일본의 쌀 생산, 유통 및 이용 현용)

  • Inouchi, Naoyoshi
    • Food preservation and processing industry
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    • v.1 no.1
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    • pp.17-26
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    • 2002
  • 일본은 기후적으로도 쌀의 생산에 적합하며 쌀은 일본의 주곡이다. 1893년 국립농업연구소가 설치된 이래로 쌀은 품질과 단보당 생산량이 꾸준히 개선되어와 116의 노동시간으로 생산량은 2.5배의 증가를 가져왔다. 이러한 진전은 재배방법의 개선, 비료, 농약, 재배기술, 기계화, 관개배수, 농지개량 등의 요인들로 볼 수 있다. 현재 일본에서 생산되고 있는 주요 쌀 품종으로는 코시히카리($35.5\%$), 히토메보레($9.7\%$), 히노히카리($9.0\%$), 아키다코마치($8.5\%$), 키라라($4.8\%$) 등 10여 품종이며 최근에는 형질전환 품종의 연구와 함께 생물공학적 연구 ,생리, 품질, 곤충과 잡초, 토양, 식품가공 등 기본적인 연구에 심혈을 기울이고 있다. 새로운 형태의 쌀 품종으로는 냉동조리쌀밥, 초밥, 레토르트룡 쌀 등 가공용으로 적합하도록 하기 위하여 아밀로오즈의 함량을 $5-15\%$로 낮춘 쌀이나 카레, 필라프, 튀김 쌀 등의 용도에 적합하도록 아밀로오스의 함량을 $30\%$이상으로 높인 쌀뿐만 아니라 곡립의 크기와 길이 등을 변형시킨 쌀, 유색미, 향미, 단백질 함량 조절 쌀, 거대 배아미, lipoxygenase 활성을 없앤 쌀, 단맛나는 쌀 등이 연구, 생산되고 있다. 일본에서의 쌀이용은 먼저 가공용 쌀을 들 수 있다. 밥, 청주, 스낵, 쌀가루, 미소발효 등 다양하게 이용이 되고 있으며 parboiled rice와 이의 색과 향을 개선한 converted rice, 현미를 이용한 가공쌀, 쌀빵, 현미가루, 세척미, 쌀국수, 쌀스낵, 당과, 죽, 쌀은 채소아 함께하는 타키코미고한, 초밥, 냉동쌀밥, 무균포장밥, 건조밥, 즉석밥 등 매우 다양하다.는 일, 쌀 재배구조 조정과 함께 높은 미질을 가지는 품종육종, 기계화를 비롯한 경작기술의 발달, 쌀과 부산물 가공기술의 개발연구, 특정기능을 함유하는 유전공학적 기술의 적용, 토지와 도시화 그리고 식량순환에 시스템의 개혁 등 과학기술을 고양하는 일 등을 들 수 있다.하는데 도움이 되리라 생각된다.=0.002)가 통계적으로 유의한 인자였다. 결론 : 본 기관에서 시행되어진 근침윤성 방광암에 대한 방광보존치료법은 기존의 근치적 방광절제술에 비하여 대등한 치료성적을 내는 동시에 $63\%$에서 장기보존이 가능하였다. 따라서 본 치료법이 방광암의 치료에 적극적으로 적용되어야 할 것으로 생각하며 향후 여러 기관이 참여하는 활발한 연구를 통해 한국인에게 가장 적절한 치료법을 개발해야 될 것으로 생각한다. B2+3, C1, C2+3군에서 수술달독군과 방사선치료 추가군의 골반종양제어율은 각각 $79\%$$75\%$ (p=0.88), $100\%$$100\%,\;44\%$$68\%$ (p=0.01)이었다. 전체 환자를 대상으로 다요인 분석을 시행한 결과 생존율과 무병생존율에 병기만이 유의하였고 두 치료 군에서도 역시 병기가 유의한 인자로 나타났다. 전체환자에서 골반종양제어율에 유의한 예후인자로 다요인분석을 시행한 결과 병기와 수술방법이 유의하였다. 수술단독군에서는 병기만이 유의하였고 방사선치료 추가군에서는 수술방법만이 유의하여 복부회음절제술군의 골반종양재발률이 높았다. 결론 : 본 후향적 연구에서 수술 후 보조적 방사선치료를 시행하여 수술단독군에 비해 병기 C2+3군에서 골반종양제어율이 향상되었음을 알 수 있었다. 그러나 병기 B2이상의 모든 환자에서 골반종양제어율 뿐만 아니라 생존율의 향상을 가져오기

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A Study on Radio-Protection Mechanism of Platelet Cells After Injection of Alliin (알리인 투여 후 혈소판의 방사선 방어기전 연구)

  • Ji, Tae-Jeong
    • Journal of radiological science and technology
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    • v.33 no.3
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    • pp.185-192
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    • 2010
  • Platelets originating from Megakaryocyte are sensitive to radiation along with white blood cells, and thus these platelets are used as an index of radiation hazard as they decrease in advance. Thus, when there is a scarcity of platelets, dot hemorrhage occurs and it leads to decrease of blood corpuscle and a decline in immunity. In particular, when 4~6 Gy whole body irradiation is received, after three weeks, the platelets will decrease to the lowest level, which can be a cause of death by bleeding and anemia. Therefore, this study tried to identify the mechanism of platelet damage and protection effect. The protection substance used in the experiment is Alliin, which is a component of garlic, and it was observed by an Transmission Electron Microscope(TEM) after its injection to the rat's tail vein. In the study, it was found that the cell membrane was severely damaged in a 10-day progressed platelet organ after receiving 5 Gy irradiation. It billowed as balloon-like figure and the glycocalyx became hyperplasia. The minute organ was damaged to the point that it was beyond recognition in a 20-day progressed platelet organ after receiving irradiation, and the cytoplasmic contents were exposed to epilepsy parts and outrageously damaged. Furthermore, the form of granules could also not be observed. A hole was formed in the middle, and the damaged organ was found in a 30-day progressed platelet. However, the form of granules was consistently maintained in the experiment group injecting Alliin, as with the control group, and there was no damage to the cell membrane recognized. Thus, it was possible to verify the effectiveness of radiation protection of the platelet when Alliin was injected to the blood vessel.

DENTAL TREATMENT IN A PATIENT WITH ANGELMAN SYNDROME DUE TO UNIPARENTAL DISOMY (편친 이염색체성 엔젤만 증후군(Angelman syndrome) 환자의 치과치료)

  • Park, Sung-Hee;Shin, Teo-Jeon;Hyun, Hong-Keun;Kim, Young-Jae;Kim, Jung-Wook;Lee, Sang-Hoon;Kim, Chong-Chul;Jang, Ki-Taeg
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.12 no.1
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    • pp.11-15
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    • 2016
  • Angelman syndrome is characterized by a partial deficit of paired autosomal chromosome 15, which contains a subunit of the GABA (Gamma-Amino Butyric Acid) receptor. The main clinical characteristics of this syndrome are delayed neuropsychological development, intellectual disability, and speech impairment. The syndrome has oral manifestations such as diastemas, tongue thrusting, sucking swallowing disorder, and excessive chewing behavior. A 3-year-6-month old girl with Angelman syndrome was scheduled for dental treatment. She had multiple caries, but she was poorly cooperative for treatment due to developmental delay and movement disorder, so general anesthesia was considered. The patient with Angelman syndrome was successfully treated under general anesthesia. There were no postoperative complications related to anesthesia and dental treatment. When treating children with this syndrome, the dentist needs to manage their uncooperative behavior and medical problem.

Star Formation Rate and AGN in Barred Galaxies (막대은하의 별탄생율과 활동성 은하핵)

  • Bang, Jun;Ann, Hong-Bae
    • Journal of the Korean earth science society
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    • v.30 no.1
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    • pp.69-80
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    • 2009
  • We investigate the dependence of star formation rate and Active Galaxy Nuclei (AGN) frequency on the bar properties, especially the bar strength, using SDSS DR6. To better represent the bar strength, we divided the bars into 6 classes according to their length and axial ratios. There seems to be a fairly good correlation between the star formation rate derived from $H{\alpha}$ emission lines and the bar strength, whereas there is no apparent correlation between the AGN activity and the bar strength. We interpret that the former correlation is due to the dependence of bar-driven gas inflow on the strength of bar. The lack of correlation between AGN and bar properties suggests that the accretion of gas onto a supermassive black hole (SMBH) is regulated by the interplay between the bar and SMBH. The frequency of AGN seems to be dependent on the background density but the star formation rate does not. It suggests that star formation is a localized phenomenon that is mostly determined by the gas density in a galaxy, while AGN activity is more closely related to the host property such as mass and luminosity that are thought to be dependent on the environment through the density-luminosity relation.

Antiproliferation Effects of Ethanol and Water Extracts from Germinated Rough Rice (발아 벼 열수 및 에탄올 추출물의 암세포주 증식억제 효과)

  • Kim, Hyun-Young;Hwang, In-Guk;Kim, Tae-Myoung;Kim, Dae-Joong;Park, Dong-Sik;Kim, Jae-Hyun;Lee, Jun-Soo;Jeong, Heon-Sang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.8
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    • pp.1107-1112
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    • 2010
  • This study was conducted to investigate the effect of 70% ethanol and water extract of Korean rough rice ('Ilpum', 'Goami2', 'Keunnun', 'Sulgaeng', 'Baegjinju', and 'Heugkwang') before and after germination on proliferation of human cancer cell lines (HepG2, PC-3, and MCF-7). Antiproliferation effect was higher in ethanol extract than water extract, and was higher in after germination. 'Ilpum' ethanol extract after germination showed higher anti-proliferation effect on HepG2 and PC-3 cell lines than before germination. The cell viability on HepG2 and PC-3 cell lines of 'Ilpum' ethanol extract after germination was 27.23% and 5.05% at 1.0 mg/mL, respectively. The anti-proliferation effect on MCF-7 was the highest in 'Ilpum' and 'Heugkwang' 70% ethanol extract after germination and those cell viabilities were 7.27% and 17.00% at 0.5 mg/mL, respectively. These results suggest that germinated rough rice might have a potentially preventive effect on human cancer cells.

Rapid Hybrid Recommender System with Web Log for Outbound Leisure Products (웹로그를 활용한 고속 하이브리드 해외여행 상품 추천시스템)

  • Lee, Kyu Shik;Yoon, Ji Won
    • KIISE Transactions on Computing Practices
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    • v.22 no.12
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    • pp.646-653
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    • 2016
  • Outbound market is a rapidly growing global industry, and has evolved into a 11 trillion won trade. A lot of recommender systems, which are based on collaborative and content filtering, target the existing purchase log or rely on studies based on similarity of products. These researches are not highly efficient as data was not obtained in advance, and acquiring the overwhelming amount of data has been relatively slow. The characteristics of an outbound product are that it should be purchased at least twice in a year, and its pricing should be in the higher category. Since the repetitive purchase of a product is rare for the outbound market, the old recommender system which profiles the existing customers is lacking, and has some limitations. Therefore, due to the scarcity of data, we suggest an improved customer-profiling method using web usage mining, algorithm of association rule, and rule-based algorithm, for faster recommender system of outbound product.

Study on Radioprotection of Alliin and Damage Mechanism in Hepatocyte After Irradiation (방사선 피폭 시 간세포의 손상 기전과 알리인의 방어효과)

  • Ji, Tae-Jeong;Kim, Won-Tae
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.623-630
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    • 2016
  • Liver tissue damage by a radiation exposure caused a jaundice and ascitic fluid e form harden atrophy. The reason for this lies in morphological damage of a liver cells. This study tried that observe damage mechanism of the cell organelles. It was especially observed mitochondria, endoplasmic reticulum and nuclear membrane associated with energy metabolizable. also, This study had with a radio-protector development research at the same time. Radio-protector was used to alliin that has an blood flow increase. Cell observation make used of transmission electron microscope(TEM). The result of an experiment, 7Gy of whole body irradiation was caused an inflammation in cell organelles and hypertrophy of the nucleus membrane. After 20 days, The hepatocyte has been observed in a damaged membrane on peroxisome, mitochondria and vacuole of the cell organelles. After 30 days, The hepatocyte has been observed in disconnected ribosomes on a rough endoplasmic reticulum. There was looked a giant lipoblast. There was clearly normal observed a mitochondria and nucleus membrane in the hepatocyte after alliin injection. aslo, It was no damaged the nucleus membrane. therefore, It was identified portion a radio-protector effect from alliin.

Dose Comparison Using Deformed Image Registration Method on Breast Cancer Radiotherapy (유방암 방사선치료에서 변형영상정합기법을 이용한 선량비교)

  • Won, Young Jin;Kim, Jong Won;Kim, Jung Hoon
    • Journal of radiological science and technology
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    • v.40 no.1
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    • pp.57-62
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    • 2017
  • The purpose of this study is to reconstruct the treatment plan by applying CBCT and DIR to dose changes according to the change of the patient's motion and breast shape in the large breast cancer patients and to compare the doses using TWF, FIF and IMRT. CT and CBCT were performed with MIM6 to create DIRCT and each treatment plan was made. The patient underwent computed tomography simulation in both prone and supine position. The homogeneity index (HI), conformity index (CI), coverage index (CVI) to the left breast as planning target volume (PTV) were determined and the doses to the lung, heart, and right breast as organ at risk (OAR) were compared by using dose-volume histogram and the unique property of each organ. The value of HI of the PTV breast increased in all treatment planning methods using DIRCT, and CVI and CI were decreased in the treatment planning methods using DIRCT.

Precisely Nondestructive Diagnosis and Slope Stability of the Bonghwa Bukjiri Maaeyeoraejwasang (Rock-Carved Seated Buddha Statue), Korea (봉화 북지리마애여래좌상의 비파괴 정밀진단과 사면안정성 분석)

  • Cho, Ji-Hyun;Jo, Young-Hoon;Chun, Yu-Gun;Choi, Joon-Hyun;Lee, Chan-Hee
    • Journal of Conservation Science
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    • v.26 no.2
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    • pp.121-132
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    • 2010
  • The Bukjiri Maaeyeoraejwasang (National Treasure No. 201) consists of two-mica granite in medium size, which was the simbol of power in the region of the Silla period. Magnetic susceptibility of the host rock was measured as 0.41(${\times}10^{-3}$ SI unit), which has the similar range with surrounding outcrop. The Buddha developed parallel discontinuous plane of NE to SW strike and damaged seriously by exfoliation, granular disintegration and brown discoloration as 41.5%, 16.7% and 40.0%, respectively. As a result of the ultrasonic velocity, which was relatively weak values as 1,629m/s (Buddha area) and 1,549m/s (surrounding outcrop), improved about 900m/s compared to last treatment. From the results of the evaluation for slope stability, identified the possibility of toppling failure in the Buddha, and planar and wedge failure in host rock. Therefore, we suggest for the safely conservation of the Buddha, continuance monitoring for understand behavior of discontinuity system of the surface, and necessitate foundation reinforcement method for the rock which has the danger of collapse.

High Resolution Rainfall Prediction Using Distributed Computing Technology (분산 컴퓨팅 기술을 이용한 고해상도 강수량 예측)

  • Yoon, JunWeon;Song, Ui-Sung
    • Journal of Digital Contents Society
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    • v.17 no.1
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    • pp.51-57
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    • 2016
  • Distributed Computing attempts to harness a massive computing power using a great numbers of idle PCs resource distributed linked to the internet and processes a variety of applications parallel way such as bio, climate, cryptology, and astronomy. In this paper, we develop internet-distributed computing environment, so that we can analyze High Resolution Rainfall Prediction application in meteorological field. For analyze the rainfall forecast in Korea peninsula, we used QPM(Quantitative Precipitation Model) that is a mesoscale forecasting model. It needs to a lot of time to construct model which consisted of 27KM grid spacing, also the efficiency is degraded. On the other hand, based on this model it is easy to understand the distribution of rainfall calculated in accordance with the detailed topography of the area represented by a small terrain model reflecting the effects 3km radius of detail and terrain can improve the computational efficiency. The model is broken down into detailed area greater the required parallelism and increases the number of compute nodes that efficiency is increased linearly.. This model is distributed divided in two sub-grid distributed units of work to be done in the domain of $20{\times}20$ is networked computing resources.