• Journal of the Korean Society of Radiology
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• v.15 no.5
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• pp.585-590
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• 2021

Wrist braces are being used for patients with wrist trauma. Recently, many studies have been conducted to manufacture custom wrist braces using 3D printing technology. Such 3D printing customized orthosis has the advantage of reflecting various factors such as reflecting different shapes for each individual and securing breathability. In this paper, the stress on the orthosis by the number and position of Velcro bands that should be considered when manufacturing a 3D printing custom wrist brace was analyzed. For customized orthosis, 3D modeling of the bone and skin regions was performed using an automatic design software (Reconeasy 3D, Seeann Solution) based on CT images. Based on the 3D skin area, a wrist orthosis design was applied to suit each treatment purpose. And, for the elasticity of the brace, a wrist brace was manufactured with an FDM-type 3D printer using TPU material. To evaluate the effectiveness according to the number and position of the Velcro band of the custom 3D printed wrist brace, the stress distribution of the brace was analyzed by the finite element method (FEM). Through the finite element analysis of the wrist orthosis performed in this study, the stress distribution of the orthosis was confirmed, and the number and position of the orthosis production and Velcro bands could be confirmed. These experimental results will help provide quality treatment to patients.

• Journal of Life Science
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• v.31 no.7
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• pp.631-640
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• 2021

Houttuynia cordata Thunberg has been studied for a variety of pharmacological actions in traditional oriental medicine. In this study, we investigated the effects of Houttuynia cordata ethanol extract (HCE) on benign prostatic hyperplasia (BPH) models induced by castration and testosterone propionate (TP) injection. Thirty rats were divided into six groups. One group was used as a normal control, and the other groups were castrated and had intraperitoneal injections of TP for 14 days to induce BPH. A positive control group was given daily doses of finasteride (5 mg/kg) to the BPH model. Rats administered HCE (0.5, 1 or 2 mg/kg) instead of finasteride were compared with controls as experimental groups. There was no statistical significance in terms of prostate weight based on 100 g of body weight. The concentrations of 5-α reductase and dehydroxytestosteronre (DHT) were determined via ELISA tests, and there was a significant decrease in all experimental groups. The 0.5 mg/kg HCE group had the lowest level of 5-α reductase, and the 2 mg/kg HCE group had the lowest level of DHT. In the histopathological observation of prostates, the control and the 2 mg/kg HCE groups had normal cell shapes and no swelling. However, in the negative control group and the 1 mg/kg HCE group, the cells were swollen, and the gap between the cells was narrowed. In particular, in the 0.5 mg/kg HCE group, some cells were bursting. Therefore, the administration of more than 2 mg/kg of HCE is suitable to protect against BPH.

• KIPS Transactions on Computer and Communication Systems
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• v.10 no.7
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• pp.199-204
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• 2021

Digital substation refers to a substation that digitizes functions and communication methods of power facilities such as monitoring, measuring, control, protection, and operation based on IEC 61850, an international standard for the purpose of intelligent power grids. Based on the intelligent operating system, efficient monitoring and control of power facilities is possible, and automatic recovery function and remote control are possible in the event of an accident, enabling rapid power failure recovery. With the development of digital technology and the expansion of the introduction of eco-friendly renewable energy and electric vehicles, the spread of direct current distribution systems is expected to expand. MVDC is a system that utilizes direct current lines with voltage levels and transmission capacities between HVDCs applied to conventional transmission systems and LVDCs from consumers. Converting existing lines in substations, where most power equipment is alternating current centric, to direct current lines will reduce transmission losses and ensure greater current capacity. The process bus of a digital substation is a communication network consisting of communication equipment such as Ethernet switches that connect installed devices between bay level and process level. For MVDC linkage to existing digital substations, the process level was divided into two buses: AC and DC, and a system that can be comprehensively managed in conjunction with diagnostic IEDs as well as surveillance and control was proposed.

• Korean Journal of Breeding Science
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• v.42 no.3
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• pp.294-297
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• 2010

A new intermediate parent 'Wonye 30001' (Allium cepa L.) was developed by Bioenergy Crop Research Center, NICS in 2009. As a male sterile line, 'Wonye 30001' could be used for hybrid seed production by crossing with pollen parent. The first cross was conducted in 2000. Male sterile plants were selected from 'Ginque' breeding lines and fertile plants were selected from YG-1-1. The male sterile line 'Wonye 30001' has circular bulb and bulb weight of 260 g. As mid-late maturing type, lodging date is around May 20. Plant height and stem diameter are 57 cm and 15.9 mm, respectively. In seed harvesting characteristics, number of flower stalks and the length are 6 and 135cm, respectively. Flowering date of 'Wonye' is May 23 and is completely male sterile. 'Wonye 30001' is a promising male sterile line for hybrid bulb onion seed production.

• Korean Journal of Breeding Science
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• v.42 no.5
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• pp.495-501
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• 2010

Peaches (Prunus persica) are less popular than the fresh fruits, because their flesh gets soft faster. So many breeders focused on their aim to firmness. Other breeders focused on juiciness, flavor and aroma. Breeding requires much labor, time and money. To reduce these requirements, many scientists develop many SSR, CAPS and SCAR makers. New peach varieties bred in our National Institute of Horticultural & Herbal Science (NIHHS) such as, Cheonhong, Suhong and Harhong are yellow flesh cultivars and Yumyeong, Baekmijosaeng, Baekhyang, Jinmi, Soomee, Mihong, Misshong and Yumee are white flesh cultivars. These peach cultivars are planted in orchard of Korea. To assert breeding cultivar patents and prevent patent disputes, we detected cultivar-specific DNA fragment using 235 sets of Operon RAPD primers, analyzed 134 DNA sequences and constructed SCAR primers. To confirm the cultivar-specific SCAR markers, we applied candidate SCAR primers to 30 peach cultivars widely cultivated in Korea. These selected lines are included father and mother lines that were used to develop new varieties in NIHHS. Using fourteen SCAR primer sets, we characterized thirty cultivars selected. The SCAR marker is expected to serve as molecular evidence distinguishing different peach varieties.

• Korean Journal of Environment and Ecology
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• v.33 no.2
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• pp.131-167
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• 2019

Securing reference information (inventory) is essential for proper conservation and management of protected areas. Moreover, the investigation results should be available for comparison and evaluation. For this study, we established seven investigational lattices and carried out the field examinations to obtain comparable data in the Donggang river basin ecological and scenery conservation area, We conducted a total of 16 field surveys and identified a total of 830 taxa that is composed of 127 families, 408 genera, 716 species, 10 subspecies, 88 varieties, and 16 forms. We identified a total of 487 taxa in the 6th investigational lattice and 457 taxa in the 4th. We observed 6 species (grade II) designated by the Ministry of Environment as the endangered plants, one "species to monitor" designated by the Ministry of Environment, and 23 taxa designated as endemic species. Regarding the floristic characteristics plants, 15 taxa of grade V, 27 taxa of grade IV, 38 taxa of grade III, 31 taxa of grade II, and 19 taxa of grade I were identified. The 6th investigational lattice showed the largest number of taxa at 70. A total of 58 taxa were identified as the naturalized plant, and the 6th investigational lattice showed the most at 35 taxa. The Donggang river basin ecological and scenery conservation area was assessed to be an extremely important area to conserve and maintain plants species diversity not only in the regional scale but also national scale.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.3
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• pp.169-183
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• 2019

Should a startup file for a patent subject to imitation in its quest to attract venture capital(VC) investors? Considering the US pharmaceutical biotechnology industry context, this paper attempts to answer this question by investigating the relations between the number of applied patents of startups, patent imitability, and the total amount of money the startups received as their first VC funding round. Data of 157 US-based pharmaceutical biotechnology startups founded in between 1995 and 2005 are analyzed. Empirical results from this study show that the number of applied patents is positively related to the total amount of money received at the time of the first funding round, and patent imitability is negatively related to the total amount of money received as first VC funding round. Nonetheless, the interaction term between the number of applied patents of startups and patent imitability came out as positive, raising interesting questions and implications for innovation-oriented startup entrepreneurs. The current study's empirical findings suggest that, in the pharmaceutical biotechnology sector, VC investors pay attention to the quantity and quality of the patents possessed by startups when they decide the level of funding. In particular, imitability of applied patents may not be a one-sided concept related to negative features such as the weak protectability of an invention. Rather, patent imitability may be a multi-facet element which also contains positive attractiveness of the startup's invention. Furthermore, it seems that the positive side of imitability can be augmented by the number of applied patents.

• Journal of Hospice and Palliative Care
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• v.22 no.3
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• pp.134-143
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• 2019

Purpose: This methodological study was conducted to test the reliability and validity of an instrument that measures attitudes of advance directives (ADs) among nurses. Methods: 1) Sixteen items related to attitudes in the English version of the Knowledge, Attitudinal, and Experiential Survey on Advance Directives (KAESAD) were forward/backward translated into Korean. 2) The content was validated by an expert panel (three nursing professors and eight hospice nursing specialists). 3) The preliminary 12 items were selected as a tool to assess the Korean version of Nurses' Attitudes towards Advance Directives (NAAD-K). 4) The instrument was validated by a survey (n=216). 5) It was confirmed to use the 12 items for the final version of the instrument. Results: NAAD-K was shown to be valid in terms of factors, items and content. The three factors extracted from the factor analysis were named as follows: Caring for patients with an AD (factor 1), nurses' role in informing patients (factor 2) and patient right (factor 3). The three factors explained total variance 57.796%. Factor loadings of the 12 items ranged from 0.47 to 0.93. For the 12 items, Cronbach's alpha was 0.81, and Guttman split-half coefficient was 0.78. Conclusion: This instrument was identified to be applicable with satisfactory reliability and validity for further use in measuring nurses' attitudes towards ADs in hospice and palliative care.

• Journal of the Korea Society for Simulation
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• v.28 no.2
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• pp.139-147
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• 2019

A MANPADS(Man Portable Air Defense System), which tracks infrared energy, is light enough for individuals to carry and can against to a variety of aircraft, making it widely deployed around the world, posing a major threat to aircraft. A flare has been developed as an IRCM(Infrared Countermeasures) that protects the life of friendly aircraft and combatants by deceiving such guided missiles. However, DIRCM, which can overcome the problems of existing IRCM, is being developed mainly in some developed countries, and the need for it has been increasing gradually. This paper modeled first generation IR seeker of AM modulation method, the second generation IR seeker of FM modulation method, and the third generation IR seeker of pulse modulation method among various MANPADS, and modeled the scattering light phenomenon in the seeker when laser beams are investigated in DIRCM. Using this, jamming simulations were performed in various engagement environments of the MANPADS and aircraft equipped with DIRCM, and the miss distance of the guided missiles and aircraft were analyzed. Simulation results show that DIRCM, which irradiates a modulated laser beam with one jamming code, deceives both first, second and third generation MANPADS at 1km and 2km of engagement distance. In particular, the survival rate of aircraft equipped with DIRCM increased when the distance of engagement increased from 1km to 2km, and the survival rate was at least 99% at 2km of engagement distance.

• The Journal of the Korea Contents Association
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• v.18 no.11
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• pp.516-526
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• 2018

Purpose: This study is to identify how depression, anxiety and social support influence on suicidal ideation of Parkinson disease patients related to general characteristics. Methods: This descriptive correlative study was conducted through an organized and structured questionnaire and 120 sampled Parkinson disease patients. Collected data was analyzed by t-tests, ANOVA, and Preason's correlation coefficient and multiple regression analysis using SPSS 19.0. Results : Finding revealed 1) The degrees of suicidal ideation were significantly different upon the martial status(F=3.37, p=.021) among groups, drinking(F=4.97, p=.008) and smoking history(F=4.77, p=.010): 2) Pearson's correlation coefficient indicated significant association among the depression, anxiety, social support and suicidal ideation 3) Multiple regression analysis showed depression(${\beta}=.58$ t=7.77, p<.001), social support(${\beta}=-.21$, t=-2.69, p=.008) and alcohol drinking(${\beta}=.17$ t=2.61, p=.010). Depression was the major influencing factor and it has 54% of explanation power. Conclusion: Based on the findings of this study, health professionals should provide parkinson disease patients with comprehensive and appropriate management method to prevent suicide ideation upon factors: depression, anxiety and social support to prevent suicide ideation. Especially, implement of self-help group program to parkinson disease patients is very needed.