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Hypofractionated Radiation Therapy for Early Glottic Cancer - Preliminary Results - (초기 성문암 환자에서의 소분할 조사법을 이용한 방사선치료 - 예비적 결과 -)

  • Wu Hong-Gyun;Hong Semie;Shin Seong Soo;Park Charn Il
    • Radiation Oncology Journal
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    • v.19 no.4
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    • pp.301-305
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    • 2001
  • Purpose : This study was peformed for the evaluation of the feasibility and toxicity of hypofractionated radiation therapy for early glottic cancer Methods and Materials : From February 1999 to February 2000, 20 patients with Histologically confirmed Stage I, II glottic cancer were enrolled into this study. There were 18 males and 2 females, the median age of the patients was 59 years. The distribution of stage distribution was as fellows; T1aN0-16 patients, T1bN0-1 patient, T2N0-3 patients. Eighteen patients underwent laryngomicroscopic biopsy only, and two patients underwent laser cordectomy. All patients received radical radiation therapy (2.5 Gy per fraction, 24 fractions, total 60 Gy). Median duration of treatment was 36 days (range $31\~45\;days$). Results : Radiation therapy were well tolerated. Most common acute reactions were odynophagia and hoarseness, and these reactions resolved after radiation therapy. There were one case of RTOG grade 3 odynophagia $(5\%)$, six cases of grade 3 hoarseness $(30\%)$. Response of radiation therapy was evaluated one month after completion of treatment. All patients revealed complete response. During follow up, total three cases of treatment failure were detected. two cases were local recurrence in 10 and 13 months of radiation therapy and one case was local recurrence and distant metastasis in 2 months of radiation therapy. Conclusion : This hypofractionated radiation therapy schedule was feasible and effective for control of early glottic cancer But longer follow up time would be required to assess the long-term disease control and the late complication by shortening radiation therapy duration.

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Effect of Band Spot Fertilization for Reduction of Additional Application in Plastic Film Mulching Cultivation of Onion(Allium cepa L.) (양파 비닐피복 재배에서 추비 절감을 위한 토중시비 효과)

  • Yang, Chang-Hyu;Ryu, Chul-Hyun;Shin, Bok-Woo;Kang, Seung-Won
    • Korean Journal of Soil Science and Fertilizer
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    • v.39 no.2
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    • pp.102-108
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    • 2006
  • It is very important to improve fertilizer use efficiency for the saving of fertilizers and for environmental purposes as well. However, there was no effective ways for the fertilization in the mid of growth under the plastic film mulching cultivation so far. For this, a Band Spotty Fertilization (BSF) machine was developed recently. So, we tried to establish a low input fertilization technique using this BSF machine in the vinyl mulching cultivation of onion (Allium cepa L.). Fertilization efficiency, soil properties, and crop yield were examined and compared among treatments from 2000 to 2001. The content of exchangeable K in soils were higher after fertilization but that of available $P_2O_5$ was lower than before the experiment in all plots. The content of nitrate-N was highest at the early growth stage, and higher in BSF plots than that of conventional fertilization (CF). BSF plot showed higher growth rate, and uptake amount of nitrogen of onion by 59-69% than that of CF. N use efficiency in BSF was higher in the order of two time-split application, one time-split application, and three time application. K use efficiency was high 13-17% BSF plots than that in CF($63kg\;ha^{-1}$) plots. The amount of residual N in soils was high by 8-14% in BSF plots compared to that in CF plots, and the loss of N was lowered 26-34% by BSF. Also, the amount of residual K in soils was high by 13-18% and the loss of K was low by 29-31% in BSF plots compared to that in CF plots. The yield of onions increased by 7-13% by BSF due to increased diameter and weight of bulbs. As the results, N fertilization efficiency increased by 22-42% by BSF.

The Optimal Combination of Major Nutrients Computed by the Homés Systematic Variation Technique -III. Determination of the Optimal Combination of Σ Anion : Σ Cation and the Optimal Application Rate of Total Ions on the Various Grassland Soils (Homés방법(方法)에 의(依)한 다량요소(多量要素)의 적정(適正) 시비비율(施肥比率) 결정(決定)에 관한 연구 -III. 초지토양별(草地土壤別) 음(陰)이온 성분총량(成分總量) : 양(陽)이온 성분총량(成分總量) 적정(適正) 시비비율(施肥比率) 및 적정(適正) 총시비량(總施肥量))

  • Jung, Yeun-Kyu;Kim, Sang-Chul;Weinberger, P.
    • Korean Journal of Soil Science and Fertilizer
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    • v.15 no.3
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    • pp.178-187
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    • 1982
  • This pot experiment was undertaken to find out the optimum fertilization ratios of total anions to total cations, ${\Sigma}A/{\Sigma}C$, and the optimum application rates of total macro-nutrients in various soil conditions. Soil samples were collected from uncultivated mountains and hills where grassland development was under consideration. 1. The optimum application ratios of ${\Sigma}A/{\Sigma}C$ and the optimum application rates of total macro-nutrients for the high yields of mixed grass-clover sward in various grassland soils were computed by the Hom$\acute{e}$s systematic variation techniqu.e. 2. With respect to the optimum application ratios of ${\Sigma}A/{\Sigma}C$ in fertilization in a mixed grass-clover sward, the grass yield and botanical composition were distinctly proportional to ${\Sigma}A$ wheras the regume yield and botanical composition were proportional to ${\Sigma}C$. 3. The optimum fertilization rates of total macro-nutrients for the high legume yields were depended upon ${\Sigma}A/{\Sigma}C$ ratios. These optimum rates were in proportional to ${\Sigma}C$ ratios and were inversely proportional to ${\Sigma}A$ ratios. 4. The efficiencies of ${\Sigma}A$ and ${\Sigma}C$ in relation to the grass and grass plus legume yields were highest with the low ratios of each other and the low fertilization rates of total macronutrients. The ${\Sigma}A$ effieiency in the legume yield tended to be similar to that of ${\Sigma}A$ related to the grass yield noted above except Daegu soil. The ${\Sigma}C$ efficiency, however, was proportional to the ${\Sigma}C$ ratio, although that was varied with the fertilization rates of total macro-nutrients and with the kinds of soils. 5. The yield of mixed forages, yield component, and botanical composition in a mixed sward were greatly influenced by the ${\Sigma}A/{\Sigma}C$ ratios, the fertilization rates of total macronutrients, and the interactions of ratio and rate noted above. In addition, these effects were generally different and opposite according to grass and legume.

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Prognostic Factors Affecting Postoperative Morbidity and Mortality in Destroyed Lung (파괴폐의 술후 합병증과 사망에 영향을 미치는 예후 인자)

  • 홍기표;정경영;이진구;강경훈;강면식
    • Journal of Chest Surgery
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    • v.35 no.5
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    • pp.387-391
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    • 2002
  • Background: Postoperative morbidity and mortality in destroyed lung are relatively high. We tried to identify the prognostic factors affecting postoperative morbidity and mortality in destroyed lung through a retrospective study. Material and method: The retrospective study was undertaken in 112 patients who had undergone pneumonectomy or pleuropneumonectomy for destroyed lung at Severance Hospital from 1970 to 2000. We analyzed the correlation between postoperative morbidity and mortality and etiology, duration of disease, preoperative FEV1, presence or absence of peroperative empyema, operation timing, the side of operation, duration of operation, and operation type. Result: There were 55 men and 57 women, aged 20 to 81 years (mean 44 years). Etiologic diseases were tuberculosis in 86 patients(76.8%) including tuberculos empyema in 20 and tuberculous bronchiectasis in 4, pyogenic empyema in 12(10,7%), bronchiectasis in 12(10.7%), and lung abscess in 2(1.8%). Postoperative morbidity were 25%(n=28) and postoperative mortality was 6%(n=7). The presence of preoperative empyema(p=0.016), pleuropneumonectomy(p=0.037) and preoperative FEV1 of less than 1.75 L(P=0.048) significantly increased the postoperative morbidity, If operation time was less than 300min, postoperative morbidity(p=0.002) and mortality(p=0.03) were significantly low. Conclusion: Postoperative morbidity and mortality in destroyed lung were acceptable. Postoperative morbidity and mortality were significantly low when operation time was less than 300 min. Preoperative existence of empyema, pleuropneumonectomy and preoperative FEV1 of less than 1.75 L significantly increased postoperative morbidity.

Knowledge and Attitude on the Restaurant-Related Sanitation of New Restaurateurs (신규 일반음식점 영업자의 위생관리 지식 및 태도)

  • Park, Ki-Hong;Sohn, Seok-Joon
    • Journal of agricultural medicine and community health
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    • v.31 no.1
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    • pp.21-34
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    • 2006
  • Objectives: The purpose of this study was to investigate the knowledge, attitude and practice toward sanitary administration of the new restaurateurs, to carry out the sanitary management of business for improvement of sanitary level, and to provide basic data which were necessary for sanitary education of the restaurateurs. Methods: The self-recording survey on the attitude and the knowledge toward the sanitation, the sanitary administration, and its education was conducted against new 393 restaurateurs by the administrative division of Gwangju city in charge of the food industry which put in the regular sanitary education annually for the new restaurateurs. Results: In regard to food sanitation, some 87.9% to 94.4% got the right knowledge about the reason and precaution of food poisoning, storage methods of frozen or cold food, and the disposal of product after expiration of validity term. But it was about 56.0% to 63.0% who knew right about the cause and the major precaution of food poisoning, storage temperature in the refrigerator. 30.6% of the subject placed an emphasis on personal sanitation of the workers as the most important thing in the sanitary management. 83.6% replied that it was necessary to improve the sanitary level. Concerning the health examination, 78.3% replied it was needed. 76.4% pointed the need for education, but respondents with higher educational level less emphasized its needs. It was most frequently pointed out by 71.6% restaurateur's poor awareness about it. 36.7% indicated the environmental sanitation like facilities in the restaurants as the first thing to be improved. The rate of personal sanitation was 43.7%. Conclusions: To improve the poor sanitary conditions of the food service business, it was recommended to offer institutional backing and financial aid from administrative office, to encourage restaurateurs to take pride in their job, and to conduct the sanitary education effectively by the technical education institution.

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Differences in Farmer's Syndrome between Greenhouse-Melon Farmers and Rice Farmers (시설참외 및 수도작 농작업자의 농부증 비교)

  • Park, Jong-Seop;Oh, Gyung-Jae
    • Journal of agricultural medicine and community health
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    • v.33 no.1
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    • pp.27-36
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    • 2008
  • =Objectives: This study was conducted to evaluate the diferences in Farmer's syndrome between greenhouse-melon farmers and rice farmers. Methods: The study included 160 residents, who lived in rural community. Of those subjects, 73 and 87 from June 1 to July 30, 2006. Respondents were interviewed by means of a structured questionnaire. Results: This study showed that greenhouse-melon farmers had a lower average age, shorter experience of farming, more working hours per day than rice farmers (p<0.05). n farmers was 38.4% respectively, the prevalence in rice farmers was 22.6%. There was statistically significant diference in the prevalence of Farmer's syndrome between greenhouse-melon and rice farmers (p<0.05). The most frequent symptoms among eight symptoms that constitute the Farmer's syndrome were lumbago, shoulder pain and nocturnal urination regardless of type of farming. But greenhouse-melon farmers had higher prevalence of muskuloskeletal symptoms, such as lumbago and shoulder pain, than rice farmers (p<0.05).Conclusions: These results showed that prevalence of Farmer's syndrome was more common in the tools which reduce physical burden and take a rest and exercise periodically during work in the greenhouse-melon farmers.

The Associations of Empowerment and Social Capital with Self-Rated Health in Communities with Poor Health (사망률이 높은 지역사회에서 임파워먼트 및 사회적 자본과 주관적 건강수준의 연관성)

  • Kim, Jang-Rak;Jeong, Baek-Geun;Park, Ki-Soo;Kang, Yune-Sik
    • Journal of agricultural medicine and community health
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    • v.37 no.3
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    • pp.131-144
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    • 2012
  • Objectives: This study was performed to identify the associations of empowerment and social capital (such as social participation and trust) with self-rated health in Korean communities with poor health. Methods: This study used the data from community health interviews conducted at 29 administrative sections (dong, eup, or myeon) with high mortality from August to October in both 2010 and 2011 as part of the Health Plus Happiness Plus Projects in Gyeongsangnam-do Province. The study subjects comprised 6,383 individuals composed of approximately 220 adults randomly sampled from each administrative section. The empowerment was measured with five-point Likert scale responses to seven perceived control questions (two at the individual level, five at the community level). The social participation was measured with 'participation in formal and/or informal group' and trust using responses to three questions about trust of others. Results: The high empowerment scores at both individual and community levels, social participation in informal groups, and high trust level had independent and significant associations with good self-rated health after adjusting for socio-demographic factors (sex, age, marital status, occupation, and food affordability) and health behaviors (smoking, alcohol drinking, and exercise) in the logistic regressions. There were weak but significant associations among empowerment, social participation, and trust levels. Conclusions: Empowerment, social participation, and trust were weakly inter-related and significantly associated with self-rated health. More studies are warranted for empowerment and other social capital indices in health promotion.

A Search of the Community between Eight Constitution Medicine and Disease Ecology: A Perspective from Medical Geography (8체질의학과 질병생태학의 공통성에 관한 연구: 의료지리학적 접근을 중심으로)

  • Kim, Changkeun;Ryu, Je-Hun;Kim, Younghoon;Park, Sookyung;Jang, YoungHun;Han, JungHoon
    • Journal of the Korean Geographical Society
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    • v.49 no.6
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    • pp.897-916
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    • 2014
  • There is a considerable community between Eight Constitution Medicine and disease ecology in that they examine the relationship between humans and environment in terms of genetic, environmental and cultural factors, in addition to the factor of germs. In this respect, the purpose of this research aims to investigate the community between Eight Constitution Medicine, a branch of Eastern Medicine and disease ecology in geography. The research method is to analyse the clinical results from 647 patients and the data from a field survey on the Yeonggwang-gun County, Jeollanam-do Province. The results are summarized as the following: First, geographical distribution of patients varies depending on the type of physical constitution; it is also divided into two types, an oceanic type and an inland type. Second, it is highly probable that there is a significant relation between a vulnerable disease in association with a type of physical constitution and patient's native place; there are diseases that are not associated with all the patients who have the same constitution; they might be incurred by the eating or life habits in association with the characteristics of geographical environment. Third, the case study of Yeonggwang-gun County, Jeollanam-do Province, with a focus on the mutual relationship among the three factors. shows that patients, who share in common the eating or life habits that coincide with their own personal types of constitution, maintain a good health condition; if not, they tend to be exposed to a various kinds of disease. Because the study on the community between Eight Constitution Medicine and disease ecology is now at the early stage, diverse types of approaches should be tried to be applied in the future.

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Analysis of the Practical Reasoning Process Presented in Home Economics Textbooks of 2007 Revised Curriculum (2007년 개정 교육과정에 기초한 7학년 가정 교과서에 반영된 실천적 추론 과정의 분석)

  • Lee, Min-Jung;Yoo, Tae-Myung
    • Journal of Korean Home Economics Education Association
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    • v.22 no.4
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    • pp.109-138
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    • 2010
  • This study examined how practical reasoning process is reflected in the 2007 revised home economics textbook of the 7th grade that is being used in schools since 2010. For a textbook analysis of the components of practical reasoning process, 12 published textbooks were all analyzed, and analysis areas were decided by reconstructing the textbook system into introduction, body contents, learning activities, evaluation. Analysis criteria were extracted from the previous literatures. Practical reasoning process was classified into Valued Ends, Context and Background, Alternatives and Means, on sequence, and Action and Reflection. As a result of analyzing categories and problems that practical reasoning process is reflected in the textbook, firstly, here was a category, which Valued Ends was absent in the practical reasoning process. In the relevant category, general problem solving progress and practical reasoning process could not be differentiated, and activity was developed with 'strategies for solution' as objective. Second, there was a category that the practical reasoning process was reflected in body contents. In this category, knowledge, concept, principle, and theory were insufficiently dealt with. Third, there was a category that reflected components of practical reasoning process but was covered with general problem solving process. Fourth, there was a category that described theme of sub-unit and body contents from the different curriculum perspectives. A curriculum perspective works as the foundation of preparing class contents or consistency of methods when developing lessons. Therefore, confusion might occur when a teacher plans a class with this kind of textbook. Fifth, a category that suggested partial components of practical reasoning process was shown the most and this category is difficult to maximize effects of practical reasoning process.

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Evaluation on the bone regenerative capacity of hyaluronic acid applied poly (D,L-lactic-co-glycolic acid) membranes in rabbit calvarial defect (Rabbit calvaria를 이용하여 hyaluronic acid (HA)를 처리한 poly (D,L-lactic-co-glycolic acid) 차폐막들의 골 생성능력에 대한 비교 연구)

  • Kim, Nam-Sook;Yun, Kwi-Dug;Vang, Mong-Sook;Yang, Hong-So;Lim, Hyun-Phil;Kang, Sung-Soo;Park, Sang-Won
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.2
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    • pp.158-165
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    • 2010
  • Purpose: The objective of the present study was to histologically evaluate durability and bone regeneration capacity of new synthetic membranes in comparison to clinically available collagen membrane. Material and methods: To the skulls of 12 rabbits, we created 4 bone defects of 6 mm in diameter on each of them. Each of defects were covered with at least one of 5 membranes; No membrane, Collagen ($Ossix^{TM}$), PLGA, HA-coated-PLGA and HA-PLGA/PLGA. After 4, 8, 12 weeks, we cut the skulls and dyed with H-E. And then, the histologic observation was done. Results: In current study, the control group which did not use the membrane showed bone regeneration at 12 weeks and covered the bone defect partially. New bones were formed through the underneath of endocranium, and the upper defect was filled with connective tissues and fats. Collagen membrane ($Ossix^{TM}$) showed new bones after 4 weeks, and they were formed through the membrane which maintained until 12 weeks. PLGA, HA-coated-PLGA, HA-PLGA/PLGA showed bone regeneration after 4 weeks and after 8 weeks, they mostly filled defects. At 12 weeks, we could find new bones and previous bones almost look alike and also, they united well. Membranes were unnoticeable after 4 weeks and were absorbed. Conclusion: Bone formation and maturation of PLGA, HA-coated-PLGA and HA-PLGA/PLGA were faster than the control group. They showed no difference on the application of HA and after 4 weeks, they were absorbed.