• Journal of Radiation Protection and Research
• /
• v.38 no.2
• /
• pp.119-123
• /
• 2013

A simple laboratory-made radioactive source to check the integrity of a gamma spectrometry system with HPGe detector was developed. The check source consists of radium-riched soil which was ground in size of less than 0.154mm and contained in air tight cylinderical vial, and provides photons with 12 distinct energies. The spectra of the check source were measured once a month during one year, analyzed the charactreictics of their peaks. When the gamma spectrometry system was in normal state, the areas and FWHMs of the gamma rays with more than 3% gamma emission rate in radium and its decay products was constant within standard deviation 2% and 3%, respectively, except 77 keV peak. And it was found that this check source can play a sufficient role to check the integrity of a gamma spectrometry system using 10 peaks in the range of 77 to 2202 keV.

• Journal of Radiation Protection and Research
• /
• v.38 no.4
• /
• pp.237-241
• /
• 2013

The gamma energy distributions at the major working places during refueling outage of Korean PWR nuclear power plants were measured. In order to estimate the dose reduction effect of a lead vest, Monte Carlo calculation method was used. For the simulations, the MIRD-V phantom with a lead vest was formed and exposed to the measured radiation field. The average measured gamma energy is lower than that of standard which is generally applied to radiation protection procedures. For the efficient use of a lead vest and achievement of radiation protection purpose, it is necessary to estimate the energy distribution of radiation field at working places.

• Journal of Radiation Protection and Research
• /
• v.28 no.1
• /
• pp.19-24
• /
• 2003

The self-attenuation factor for an $^{198}Au$ sample and the 0.412 MeV gamma-ray penetration ratio in the circular Al-cover of the radiation detector have been determined using an analytical solution and MCNP code. The results show that the self-attenuation factors obtained from the analytical solution coincide with those of MCNP code for all but the Au sample with the relatively larger radius. Then the maximum difference between the two methods appears to be 9 % in the Au sample of 1.5 mm radius. It also is revealed that the analytical solutions of the 0.412 MeV gamma-ray penetration ratio in the Al-cover of 7.62 cm radius are consistent with those of the MCNP code within the standard deviation.

• The Korean Journal of Applied Statistics
• /
• v.28 no.2
• /
• pp.221-230
• /
• 2015

Traditionally, sib-pair linkage analysis with repeated measures has employed linear mixed models, but it suffers from the lack of power to find genetic marker loci associated with a phenotype of interest. In this paper, we use a gamma mixed model to improve sib-pair linkage analysis and compare it with a linear mixed model in terms of power and Type I error. We illustrate that the use of gamma mixed model can achieve higher power than linear mixed model with Genetic Analysis Workshop 13 data.

• The Korean Journal of Applied Statistics
• /
• v.1 no.2
• /
• pp.27-33
• /
• 1987

Let $\Pi_i, \cdots, \Pi_k$ denote k gamma distributions with a common known shape parameter (degrees of freedom) r and scale parameters $\theta_1, \cdots, \theta_k$, respectively. Kim proposed an improved lower bound LB$(\delta^*)$, which concerns a two-stage elimimation type procedure for selecting the population associated with the largest scale parameter $max_{1\leqi\leqk} \theta_i$. The design constants (nr, mr, c) are given for k=4(1)10, $p^*=.95,.90 and \delta^*=1.75,2.0$. With these design constants, a comparison study was made with the procedure of Lee and Choi. As can be seen from the table, these are moderate amount of savings in the expected total sample size. Thus, together with the result in Lee and Choi, the two-stage procedure can perform much better than a single stage procedure.

• Journal of Periodontal and Implant Science
• /
• v.35 no.1
• /
• pp.133-152
• /
• 2005

1. 목적 Prostaglandin은 치주질환과 관련된 국소적 골 대사에 중요한 역할을 한다. ${\Delta}^{12}PGJ_2$는 생체 내에서 혈장의 존재 하에 형성되는 천연 $PGD_2$ 대사산물이며 peroxisome- proliferator에 의해 활성화되는 감마 수용체 (PPAR ${\Gamma}$)에 대해 높은 친화성을 갖는 리간드로서 핵 수용체군에 속하는 전사조절인자이다. 이 연구의 목적은 골화 과정에서 ${\Delta}^{12}PGJ_2$의 역할을 규명하기 위해, 조골세포주의 증식과 분화에 미치는 영향과 그에 관련된 세포기전을 조사하는 데에 있다. 2. 방법 인간 골육종세포주인 Saos-2 (ATCC.HTB 85)와 쥐의 조골세포주 (MC3T3-E1)를 배양한 후 실험군에 농도가 각각 $10^{-5}$, $10^{-6}$, $10^{-7}$, $10^{-8}$, $10^{-9}$ 몰인 ${\Delta}^{12}PGJ_2$와 ciglitazone (합성 PPAR 감마 길항체)를 첨가하였다. 조골세포에서 PPAR 감마의 발현을 관찰하기 위해 역전사효소-중합효소연쇄반응(RT-PCR)을 특정한 primer를 이용하여 시행하였다. 세포 증식은 1일, 2일, 3 일째에 MIT 분석법으로 측정하였고, 2 일째에 알칼리성 인산효소 (ALPase) 생산을 측정하였다. 위의 결과에서 얻은 적정한 농도에서 다양한 조골세포 분화의 표지자들-제 1 형 교원질, 알칼리성 인산효소, osteopontin 및 bone sialoprotein-에 대한 간이 정량적 역전사효소-중합효소연쇄반응 (semiquantitative RT-PCR)을 실시하였으며 골결절 형성에 대한 효과를 알아보고자 석회화 분석도 시행하였다. 3. 결과 ${\Delta}^{12}PGJ_2$와 ciglitazone 모두 Saos-2 세포주의 증식을 촉진시켰다 .$10^{-8}$ 몰의 ${\Delta}^{12}PGJ_2$와 $10^{-6}$몰의 ciglitazone을 첨가한 실험군을 대조군과 비교했을 때, 시간에 비례하여 세포 증식률이 증가되었다. 알칼리성 인산효소의 활성화 검사에서도 증식률에서와 유사한 결과를 보여주었다. 간이 정량적 RT-PCR에서는 ${\Delta}^{12}PGJ_2$로 처리한 군의 경우 제 1 형 교원질, 알칼리성 인산효소, osteopontin, 그리고 bone sialoprotein의 상대적 mRNA 수준이 유의하게 높았다. 석회화 분석에서는 MC3T3-E1 세포를 $10^{-6}$ 몰의 ${\Delta}^{12}PGJ_2$로 처리한 군과 $10^{-5}$ 몰의 ciglitazone으로 처리한 군에서 현저한 골결절 형성을 보였다. 이러한 결과들은 ${\Delta}^{12}PGJ_2$가 유용한 골 유도물질이 될 수 있으며 또한 그 작용기전이 PPAR 감마-의존형 경로와 연관되어 있음을 보여준다.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.25 no.5
• /
• pp.796-803
• /
• 1996

Gamma irradiation was applied to soybean(Glycine max.), Hwangkeum, at dose levels of 0, 5, 10 and 20 kGy to improve the physical properties of soybeans. The time to reach a fixed moisture content was reduced depending on the increment of soaking temperatures and applied irradiation dose levels. Irradiation at 5~20 kGy resulted in reduction in soaking time of the soybeans by about 3~6 hrs at soaking temperature of $20^{\circ}C.$ The degree of cooking of soybeans in boiling water was determined by measuring the maximum cutting force of cotyledon. The cutting force to reach complete cooking was about 145g/g. Irradiation at 5~20 kGy resulted in a reduction of cooking time of soybeans by 55~75% as compared to the nonirradiated soybean. In electron microscopic observation of seed coat inner, the parenchyma of nonirradiated soybean showed tight fibrillar structure, whereas that of irradiated soybeans showed loosened and deformed structure. The microstructure of compressed cells and cotyledon epidermis was also deformed by gamma irradiation. In subcellular structure of cotyledon, the roundness of protein body was deformed and changed to spike shape at 20 kGy. Also, the size of lipid body decreased as the irradiation dose levels increased.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2010.05a
• /
• pp.393-394
• /
• 2010

• 대한방사선방어학회:학술대회논문집
• /
• 2010.04a
• /
• pp.164-165
• /
• 2010

• 대한방사선방어학회:학술대회논문집
• /
• 2009.04a
• /
• pp.184-185
• /
• 2009