• Title/Summary/Keyword: 가변형

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Phase Behavior of Simvastatin Drug in Mixtures of Dichloromethane and Supercritical Carbon Dioxide and Microparticle Formation of Simvastatin Drug Usins Supercritical Anti-Solvent Process (디클로로메탄과 초임계 이산화탄소의 혼합용매에서 Simvastatin 약물의 상거동과 초임계 역용매 공정을 이용한 Simvastatin 약물 미세입자의 제조)

  • Oh, Dong-Joon;Lee, Byung-Chul
    • Clean Technology
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    • v.13 no.1 s.36
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    • pp.34-45
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    • 2007
  • Phase behavior of the ternary systems of water-insoluble simvastatin drug, which is well known to be effective drugs for hypercholesterolemia therapy, in solvent mixtures of dichloromethane and supercritical carbon dioxide was investigated to present a guideline of establishing operating conditions in the particle formation of the drugs by a supercritical anti-solvent recrystallization process utilizing dichloromethane as a solvent and carbon dioxide as an anti-solvent. The solubilities of simvastatin in the mixtures of dichloromethane and carbon dioxide were determined as functions of temperature, pressure and solvent composition by measuring the cloud points of the ternary mixtures at various conditions using a high-pressure phase equilibrium apparatus equipped with a variable-volume view cell. The solubility of the drug increased as the dichloromethane composition in solution and the system pressure increases at a fixed temperature. A lower solubility of the drug was obtained at a higher temperature. The second half of this work is focused on the particle formation of the simvastatin drug by a supercritical anti-solvent recrystallization process in a cylindrical high-pressure vessel equipped with an impeller. Microparticles of the simvastatin drug were prepared as functions of pressure (8 MPa to 12 MPa), temperature (303.15 K, 313,15 K), feed flow rate of carbon dioxide, and stirring speed (up to 3000 rpm), in order to observe the effect of those process parameters on the size and shape of the drug microparticles recrystallized.

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A Parametric Study of Pulsed Gamma-ray Detectors Based on Si Epi-Wafer (실리콘 에피-웨이퍼 기반의 펄스감마선 검출센서 최적화 연구)

  • Lee, Nam-Ho;Hwang, Young-Gwan;Jeong, Sang-Hun;Kim, Jong-Yeol;Cho, Young
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.7
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    • pp.1777-1783
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    • 2014
  • In this paper, we designed and fabricated a high-speed semiconductor sensor for use in power control devices and analyzed the characteristics with pulsed radiation tests. At first, radiation sensitive circular Si PIN diodes with various diameters(0.1 mm ~5.0 mm) were designed and fabricated using Si epitaxial wafer, which has a $42{\mu}m$ thick intrinsic layer. The reverse leakage current of the diode with a radius of 2 mm at a reverse bias of 30 V was about 20.4 nA. To investigate the characteristic responses of the developed diodes, the pulsed gamma-radiation tests were performed with the intensity of 4.88E8 rad(Si)/sec. From the test results showing that the output currents and the rising speeds have a linear relationship with the area of the sensors, we decided that the optimal condition took place at a 2 mm diameter. Next, for the selected 2 mm diodes, dose rate tests with a range of 2.47E8 rad(Si)/sec to 6.21E8 rad(Si)/sec were performed. From the results, which showed linear characteristics with the radiation intensity, a large amount of photocurrent over 60mA, and a high speed response under 350ns without saturation, we can conclude that the our developed PIN diode can be a good candidate for the sensor of power control devices.

Performance Improvement of an Energy Efficient Cluster Management Based on Autonomous Learning (자율학습기반의 에너지 효율적인 클러스터 관리에서의 성능 개선)

  • Cho, Sungchul;Chung, Kyusik
    • KIPS Transactions on Computer and Communication Systems
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    • v.4 no.11
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    • pp.369-382
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    • 2015
  • Energy aware server clusters aim to reduce power consumption at maximum while keeping QoS(quality of service) compared to energy non-aware server clusters. They adjust the power mode of each server in a fixed or variable time interval to activate only the minimum number of servers needed to handle current user requests. Previous studies on energy aware server cluster put efforts to reduce power consumption or heat dissipation, but they do not consider energy efficiency well. In this paper, we propose an energy efficient cluster management method to improve not only performance per watt but also QoS of the existing server power mode control method based on autonomous learning. Our proposed method is to adjust server power mode based on a hybrid approach of autonomous learning method with multi level thresholds and power consumption prediction method. Autonomous learning method with multi level thresholds is applied under normal load situation whereas power consumption prediction method is applied under abnormal load situation. The decision on whether current load is normal or abnormal depends on the ratio of the number of current user requests over the average number of user requests during recent past few minutes. Also, a dynamic shutdown method is additionally applied to shorten the time delay to make servers off. We performed experiments with a cluster of 16 servers using three different kinds of load patterns. The multi-threshold based learning method with prediction and dynamic shutdown shows the best result in terms of normalized QoS and performance per watt (valid responses). For banking load pattern, real load pattern, and virtual load pattern, the numbers of good response per watt in the proposed method increase by 1.66%, 2.9% and 3.84%, respectively, whereas QoS in the proposed method increase by 0.45%, 1.33% and 8.82%, respectively, compared to those in the existing autonomous learning method with single level threshold.

Three Dimensional Implementation of Intelligent Transportation System Radio Frequency Module Packages with Pad Area Array (PAA(Pad Area Array)을 이용한 ITS RF 모듈의 3차원적 패키지 구현)

  • Jee, Yong;Park, Sung-Joo;Kim, Dong-Yong
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.1
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    • pp.13-22
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    • 2001
  • This paper presents three dimensional structure of RF packages and the improvement effect of its electrical characteristics when implementing RF transceivers. We divided RF modules into several subunits following each subunit function based on the partitioning algorithm which suggests a method of three dimension stacking interconnection, PAA(pad area array) interconnection and stacking of three dimensional RF package structures. 224MHz ITS(Intelligent Transportation System) RF module subdivided into subunits of functional blocks of a receiver(RX), a transmitter(TX), a phase locked loop(PLL) and power(PWR) unit, simultaneously meeting the requirements of impedance characteristic and system stability. Each sub­functional unit has its own frequency region of 224MHz, 21.4MHz, and 450KHz~DC. The signal gain of receiver and transmitter unit showed 18.9㏈, 23.9㏈. PLL and PWR modules also provided stable phase locking, constant voltages which agree with design specifications and maximize their characteristics. The RF module of three dimension stacking structure showed $48cm^3$, 76.9% reduction in volume and 4.8cm, 28.4% in net length, 41.8$^{\circ}C$, 37% in maximum operating temperature, respectively. We have found that three dimensional PAA package structure is able to produce high speed, high density, low power characteristics and to improve its functional characteristics by subdividing RF modules according to the subunit function and the operating frequency, and the features of physical volume, electrical characteristics, and thermal conditions compared to two dimensional RF circuit modules.

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A Design and Adaptation Technique of UML-based Layered Meta-Model for Component Development (컴포넌트 개발을 위한 UML 기반의 계층형 메타 모델 설계 및 적용기법)

  • Lee, Sook-Hee;Kim, Chul-Jin;Cho, Eun-Sook
    • Journal of the Korea Society for Simulation
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    • v.15 no.2
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    • pp.59-69
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    • 2006
  • Component-based software development is introduced as a new development paradigm in software development method. This approach is different from existing software development approach because it is based on reusable and autonomous unit, component. Therefore, component-based development(CBD)is divided into two stages; component development process and component assembly process; application development process. Component development process is the core of CBD because component has a key for good software. Currently many methodologies or tools have been introduced by various academies or industries. However, those don't suggest systematic and flexible modeling techniques adaptable easily into component development project. Existing approaches have a unique orarbitrary modeling technique or provide heuristic guidelines for component modeling. As a result, many component developers are faced with a difficult problems; how to developcomponent models, when develop which diagrams, and so on. In order to address this problem, we suggest a meta-model driven approach for component development in this paper. We provide meta-models according to both layer and development phase. We expect that suggested meta-models allow component developers to develop appropriate models of the time.

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Development of Screening Technology for Marine Waste Disposal (수산폐기물 전처리 용 스크린기술 개발)

  • Moon, Serng-Bae;Jun, Seung-Hwan;Jin, Gang-Gyoo
    • Journal of Navigation and Port Research
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    • v.33 no.1
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    • pp.57-63
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    • 2009
  • In order to effectively isolate the marine wastes with an effluent standard, the pretreatment process is required to isolate solid materials from the liquid-solid mixed wastes. The more effective the pretreatment becomes, the more processing capacity of posttreatment will be improved and process facilities will be downsized. In this paper, we suggested the vibrating reverse-slant screen, investigated the optimal vibration frequency and vibrator installation angle for the separation of the liquid solid mixed wastes. Several experiments for separation efficiency were conducted under the condition of various vibration frequency($35{\sim}60Hz$, 5Hz interval) and vibrator angle($0^{\circ}$, $30^{\circ}$, $45^{\circ}$, $90^{\circ}$) considering the crack of screen. The screen inclination angle is set up the gradient as $3^{\circ}{\sim}5^{\circ}$ through the preliminary experiments. Also, we made two types of screen(respectively rectangle and square screen). The separation device has shown the optimum efficiency at vibrator angle $0^{\circ}$ and vibration frequency 60Hz, and has no relation with the shape of screen. And the proposed technology is verified by comparing with quantity of suspended solids before and after filtration.

Response Properties of Meridians for focused variable electromagnetic stimulus (접속형 가변 전자계 자극에 대한 경락반응특성)

  • Lee, Gyoun-Jung;Cho, Dong-Guk;Kim, Soo-Byung;Kwon, Sun-Min;Shin, Tae-Min;Lee, Kyoung-Joung;Lee, Yong-Heum
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.7
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    • pp.1399-1410
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    • 2009
  • It is a method to treat pain using medication, neurotomy, and surgery. And acupuncture, ultrasound, electric treatment, and magnetic treatment are applied as a alternative physiotherapy. Electronic therapy is useful but it can be affected by impedance of skin or subcutaneous tissue. So, percutaneous stimulation is leading therapy, that is very randomly. We developed the system which can stimulate parts of acupuncture point noninvasively using the focused magnetic field. And we designed the magnetic stimulation electrode which is considered efficiency of the magnetic stimulation. It can make similar stimulation with manual acupuncture. To confirm the availability and reliability we compared Meridian Electronic Potential(MEP) change between manual acupuncture and magnetic stimulation. From this result, we found out the MEP changes of manual acupuncture and magnetic stimulation were similar. And there were various response properties as changes of stimulation method, intensity, and frequency. Also, the MEP change can be induced by electromagnetic stimulation. We confirmed that it is possible to use electromagnetic stimulation as a acupoint stimulation or pain treatment instrument.

Development of the Automatic Watering System for the Soybean Sprouting Equipment by Siphon and Well Bucket (싸이펀과 두레박을 이용한 콩나물 재배기용 자동 수주 시스템 개발)

  • Kim, Joong-Man;Choi, Yong-Bae;Hwang, Ho-Sun;Yang, Dai-Ki;Jeon, Ye-Jung;Song, Young-Ae
    • Korean Journal of Food Science and Technology
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    • v.34 no.3
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    • pp.533-535
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    • 2002
  • The new watering system for the cabinet type of soybean sprouting equipment was developed. It was made of one siphon $({\Phi}35 mm)$, one well bucket $(13{\times}10{\times}10\;cm)$ that its weight-center is changed by water level, and bottle-neck water tank (bottom: $18.5^W{\times}32^L{\times}29^H\;cm$, top: $14^W{\times}14^L{\times}25^H\;cm)$. The watering system can be automatically watered more than 750 mL/sec without electric supply. The soybean sprouting equipment is consisted of the watering system and nine sprouting buckets. In addition siphon phenomena brought about easily by narrowing same as bottle-neck shape top portion of water tank that inserted a siphon. The equipment with the watering system may be produced more than three box a day in the condition of $25{\pm}1^{\circ}C$, and $6{\sim}7$ watering times a day.

Gesture Spotting by Web-Camera in Arbitrary Two Positions and Fuzzy Garbage Model (임의 두 지점의 웹 카메라와 퍼지 가비지 모델을 이용한 사용자의 의미 있는 동작 검출)

  • Yang, Seung-Eun
    • KIPS Transactions on Software and Data Engineering
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    • v.1 no.2
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    • pp.127-136
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    • 2012
  • Many research of hand gesture recognition based on vision system have been conducted which enable user operate various electronic devices more easily. 3D position calculation and meaningful gesture classification from similar gestures should be executed to recognize hand gesture accurately. A simple and cost effective method of 3D position calculation and gesture spotting (a task to recognize meaningful gesture from other similar meaningless gestures) is described in this paper. 3D position is achieved by calculation of two cameras relative position through pan/tilt module and a marker regardless with the placed position. Fuzzy garbage model is proposed to provide a variable reference value to decide whether the user gesture is the command gesture or not. The reference is achieved from fuzzy command gesture model and fuzzy garbage model which returns the score that shows the degree of belonging to command gesture and garbage gesture respectively. Two-stage user adaptation is proposed that off-line (batch) adaptation for inter-personal difference and on-line (incremental) adaptation for intra-difference to enhance the performance. Experiment is conducted for 5 different users. The recognition rate of command (discriminate command gesture) is more than 95% when only one command like meaningless gesture exists and more than 85% when the command is mixed with many other similar gestures.

Study of the Effect of the Transmittance of a Diffuser Plate on the Optical Characteristics of High-power Quantum-dot Illumination (확산판의 투과율이 고출력 양자점 조명의 광특성에 미치는 영향에 대한 연구)

  • Kim, Hye-Rin;You, Dong Geun;You, Jae Hwan;Jang, Jun Won;Choi, Moo Kyu;Hong, Seung Chan;Ko, Jae-Hyeon;Joe, Sung-Yoon;Kim, Yongduk;Park, Taehee;Ko, Young Wook
    • Korean Journal of Optics and Photonics
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    • v.32 no.5
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    • pp.220-229
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    • 2021
  • The optical characteristics of high-power direct-lit white light-emitting diode (LED) lighting were investigated, where a quantum dot (QD) film was adopted to enhance the color-rendering index (CRI). The transmittance of the diffuser plate and the concentration of the QD film were varied in this study. The color coordinates and the correlated color temperature (CCT) did not show any appreciable change, while the CRI values increased slightly as the transmittance of the diffuser plate decreased. The investigated optical properties were nearly independent of the viewing angle, and the luminance distribution was close to Lambertian. The CCT decreased from approximately 6000 K to approximately 4000 K as the concentration of the QD film increased from 0 to 7.5 wt%, which was due to the enhanced red component in the emission spectrum. The CRI increased to approximately 95 for some optical configurations of the lighting. These results demonstrate that glare-free, color-changeable, high-rendering LED lighting can be realized by using a combination of a diffuser plate of appropriate transmittance and a red QD film.