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A study on characteristics of the autonomic nervous system in students with Keongke - Using Heart Rate Variability and Pupil Size Variability - (경계(驚悸) 증상을 지닌 학생 집단의 자율 신경 기능 특성에 대한 연구 - 심박변이도와 동공크기 변이도를 중심으로 -)

  • Lee, Seung-Gi;Lee, Jeong-Chan;Kim, Ji-Eun;Park, Kyung-Mo;Kang, Hee-Chul
    • Journal of Oriental Neuropsychiatry
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    • v.17 no.2
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    • pp.133-145
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    • 2006
  • Objective : The purpose of this experimental-controlled study was to investigate the characteristics of the autonomic nervous system in students with Keongke by using HRV(Heart rate variability) and PSV(Pupil size variability). Method : The study group was consisted of 11 students with self recognition as the experimental group, and 25 normal students as the control group. Informations on gender and age were obtained by medical charts and personal interviews. By using heart rate variability and pupil size variability, we measured the value of HRT(Heart rate), SDNN(Standard deviation of NN intervals), LFnorm(Low frequency normalization), HFnorm(High frequency normalization), LF/HF ratio, Pupil area, B.S.(Basic size), C.R.(Max Constriction Rate) and 1s.d.(1sec Dilation Rate). I compared the degrees of the sympathetic and parasympathetic activity. Result : 1. In the result of heart rate variability between experimental and control group, none of the parameters of experimental group were significantly different from control group. And even though there were no statistical significance, there were some numerical differences in SDNN, LF norm, HF norm. 2. In pupil size variability, C.R. and 1s.d. of the experimental group were increased compared to control group. Conclusion : The study results suggest that the group with Keongke has differences of autonomic nervous system as compared to those in normal state. Measurement value of PSV is a new technical approach to estimate the autonomic nervous system.

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Association Between Serum Uric Acid Level and Metabolic Syndrome

  • Lee, Ju-Mi;Kim, Hyeon-Chang;Cho, Hye-Min;Oh, Sun-Min;Choi, Dong-Phil;Suh, Il
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.3
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    • pp.181-187
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    • 2012
  • Objectives: Serum uric acid levels have been reported to be associated with a variety of cardiovascular conditions. However, the direct association between uric acid levels and metabolic syndrome remains controversial. Thus, we evaluated the association of serum uric acid levels and metabolic syndrome in a community-based cohort study in Korea. Methods: We performed cross-sectional analysis of baseline data of 889 males and 1491 females (aged 38 to 87) who participated in baseline examinations of the Korean Genome and Epidemiology Study: Kanghwa study. Blood samples were collected after at least an 8 hour fast. Uric acid quartiles were defined as follows: <4.8, 4.8-<5.6, 5.6-<6.5, ${\geq}6.5$ mg/dL in males; and <3.8, 3.8- <4.3, 4.3 - <5.1, ${\geq}5.1$ mg/dL in females. Metabolic syndrome was defined by the National Cholesterol Education Program Adult Treatment Panel III Criteria with adjusted waist circumference cutoffs (90 cm for males; 80 cm for females). The association between serum uric acid quartiles and metabolic syndrome was assessed using multivariate logistic regression. Results: The odds ratio for having metabolic syndrome in the highest versus lowest quartiles of serum uric acid levels was 2.67 (95% confidence interval [CI], 1.60 to 4.46) in males and 2.14 (95% CI, 1.50 to 3.05) in females after adjusting for age, smoking, alcohol intake, body mass index, total cholesterol, HbA1c, albumin, ${\gamma}$-glutamyltransferase, blood urea nitrogen, and log C-reactive protein. The number of metabolic abnormalities also increased gradually with increasing serum uric acid levels (adjusted p for trend < 0.001 in both sexes). Conclusions: Higher serum uric acid levels are positively associated with the presence of metabolic syndrome in Korean males and females.

The Effect of Stream Anion and River-Bed Materialson Aquatic Insects (계류수의 음이온과 하상재료가 수서곤충에 미치는 영향)

  • Seo, Mun Won;Chun, Kun-Woo
    • Journal of Forest and Environmental Science
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    • v.15 no.1
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    • pp.89-97
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    • 1999
  • This study was carried out to obtain basic data on the kinds of aquatic insects and their living conditions in the mountain stream. The investigation was done in Bongmyung stream. Experimental Forest, Kangwon National University on aquatic insects, anions and river-bed materials. The results are as follows. 1. At every plot surveyed, diversity index, richness index and evenness index of aquatic insects appeared higher at upper stream than at lower stream in erosion control dam. 2. Anion concentrations were almost the same in plots A, B, C, D and E, but plot F at the lower stream showed 1.5 to 89 times higher concentration than the others. 3. In river-bed materials analysed, particle diameter was bigger at the upper stream than at the lower stream. At the down stream of erosion control dam showed high pebble composition ratio. 4. The number of aquatic insects showed the negative relation with the anion concentration and the positive one with the size of river-bed materials. Especially, they were affected much by the distribution chart of boulder.

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Electrical Properties of PNN-PMN-PZT ceramics for Rosen Type Transformer Applications (Rosen type 변압기 응용을 위한 PNN-PMN-PZT 세라믹스의 전기적 특성)

  • Joo, H.K.;Kim, I.S.;Song, J.S.;Kim, M.S.;Jeong, S.J.;Lee, D.S.
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.1244-1245
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    • 2008
  • Recently, piezoelectric transformer is applied to wide fields. Multi layer piezoelectric transformer has the advantage of high step up ratio, electromechanical coupling coefficient(Kp) and mechanical quality factor(Qm), but is indicated of peeling-phenomenon of electrode, rising sintering temperature made price of costly electrode. So in this study, it discuss on method for fabrication of rosen type piezoelectric transformers. For the fabrication as rosen type piezoelectric transformers, synthesized the powder using 0.01Pb$(ni_{1/3}Nb_{2/3})O_3$ - 0.08Pb$(Mn_{1/3}Nb_{2/3})O_3$ - 0.91Pb$(Zr_{0506}Ti_{0496})O_3$ (abbreviated as PNN-PMN-PZT) ceramics. The density, microstructure, dielectric and piezoelectric properties as a function of sintering temperature were investigated. The results indicated that the optimized properties of ceramics were obtained at sintering temperature of 1200$^{\circ}C$, showed the value of $d_{33}$=273pC/N, $K_p$=0.60 $Q_m$=1585, ${\varepsilon}_r$=1454, density=7.917$g/cm^3$ and $tan{\delta}$=0.0064.

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Immune Responses in Broiler Chicks Fed Propolis Extraction Residue-supplemented Diets

  • Eyng, C.;Murakami, A.E.;Santos, T.C.;Silveira, T.G.V.;Pedroso, R.B.;Lourenco, D.A.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.1
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    • pp.135-142
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    • 2015
  • This study was conducted to evaluate the effect of inclusion of propolis extraction residue in the feed of broilers from 1 to 21 d of age on phagocytic activity of macrophages, cutaneous basophil hypersensitivity response to phytohemagglutinin, antibody production against Newcastle disease, lymphoid organ weight and hematological profile and to determine the optimal level of inclusion. 120 chicks, reared in metabolism cages until 21 days of age, were distributed in a completely randomized design, with five treatments (0%, 1%, 2%, 3%, and 4% of propolis residue) and six replications. The relative weight of thymus and monocyte percentage were affected by propolis residue, with a quadratic response (p<0.05) and lowest values estimated at 2.38% and 2.49%, respectively. Changes in relative weight of cloacal bursa and spleen, percentage of lymphocyte, heterophil, basophil, eosinophil, and heterophil:lymphocyte ratio, antibody production against Newcastle disease, phagocytic activity of macrophages and the average number of phagocytosed erythrocytes were not observed. The nitric oxide production with regard to positive control (macrophages+erythrocytes) decreased linearly (p<0.05) with increased doses of propolis residue. The remaining variables of nitric oxide production (negative control - macrophages, and difference between the controls) were not affected by propolis residue. The cutaneous basophil hypersensitivity response to phytohemagglutinin as determined by the increase in interdigital skin thickness exhibited a quadratic response (p<0.05), which predicted a lower reaction response at a dose of 2.60% of propolis residue and highest reaction response after 43.05 hours of phytohemagglutinin injection. The inclusion of 1% to 4% of propolis extraction residue in broiler diets from 1 to 21 days of age was not able to improve the immune parameters, despite the modest changes in the relative weight in thymus, blood monocyte percentage, nitric oxide concentration, and interdigital reaction to phytohemagglutinin.

Direct Coombs Test Positivity in B-Chronic Lymphoid Leukemia: a Marker of Advanced Clinical Disease

  • Abbas, Syeda Alia;Zeeshan, Rozina;Sultan, Sadia;Irfan, Syed Mohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6007-6010
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    • 2015
  • Background: Chronic lymphoid leukemia (CLL) is a malignant hematopoietic disorder, the most common of all adult leukemias with a distinctive immunophenotype. It is well established that CLL patients can have autoimmune complications, amongst them autoimmune hemolytic anemia as the most frequent. This study was carried out to determine the frequency of direct Coombs Test positivity in CLL patients and its possible correlation with Rai staging, hematological parameters and biochemical markers. Materials and Methods: This descriptive cross sectional study was carried at Liaquat National Hospital from January 2011 to June 2013. Sixty untreated patients with B- chronic lymphoid leukemia were enrolled. Complete blood count, direct Coombs test, serum urea, creatinine, uric acid and LDH levels were determined. Data were compiled and analyzed using SPSS version 21. Results: Out of 60 patients, 42(70%) were males and 18(30%) were females. Mean age was $59{\pm}9.2years$. Male to female ratio was 2.1: 1. The frequency of direct antiglobulin test (DAT) positivity was found to be 23.3%. The monospecific IgG was positive in 11 patients (18.3%); C3d positivity was evident in 1 patient (1.6%) and 2 patients (3.3%) had dual IgG and C3d positivity. The mean hemoglobin was $10.8{\pm}2.4gm/dl$. Significantly low mean hemoglobin of $8.3{\pm}3.0gm/dl$ was seen in Coombs positive patients compared with negative patients having a mean hemoglobin level of $11.7{\pm}1.6gm/dl$ (P<0.001). DAT positivity also demonstrated a positive association with advanced Rai stage III disease (P<0.01). No associations were noted with age, gender and biochemical markers. Conclusions: Direct Coombs test positivity in CLL in our patients, unlike in Western studies, appears relatively high, indicating significant autoimmune hemolytic anemia and advanced Rai stage in our setting. DAT positivity can be considered as a surrogative marker for advanced clinical disease.

Prognostic Value of Vascular Endothelial Growth Factor Expression in Resected Gastric Cancer

  • Liu, Lei;Ma, Xue-Lei;Xiao, Zhi-Lan;Li, Mei;Cheng, Si-Hang;Wei, Yu-Quan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3089-3097
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    • 2012
  • Background and Aims: Vascular endothelial growth factor (VEGF) is a potential prognostic biomarker for patients with resected gastric cancer. However, its role remains controversial. The objective of this study was to conduct a systematic review and meta-analysis of published literature. Methods: Relevant literature was identified using Medline and survival data from published studies were collected following a methodological assessment. Quality assessment of eligible studies and meta-analysis of hazard ratio (HR) were performed to review the correlation of VEGF overexpression with survival and recurrence in patients with gastric cancer. Results: Our meta-analysis included 44 published studies with 4,794 resected patients. VEGF subtype for the prediction of overall survival (OS) included tissue VEGF (HR=2.13, 95% CI 1.71-2.65), circulating VEGF (HR=4.22, 95% CI 2.47-7.18), tissue VEGF-C (HR=2.21, 95% CI 1.58-3.09), tissue VEGF-D (HR=1.73, 95% CI 1.25-2.40). Subgroup analysis showed that HRs of tissue VEGF for OS were, 1.78 (95% CI 0.90-3.51) and 2.31 (95% CI 1.82-2.93) in non-Asians and Asians, respectively. The meta-analysis was also conducted for disease free survival (DFS) and disease specific survival (DSS). Conclusion: Positive expression of tissue VEGF, circulating VEGF, VEGF-C and VEGF-D were all associated with poor prognosis in resected gastric cancer. However, VEGF demonstrated no significant prognostic value for non-Asian populations. Circulating VEGF may be better than tissue VEGF in predicting prognosis.

Effects of Fermented Soy Protein on Growth Performance and Blood Protein Contents in Nursery Pigs

  • Min, B.J.;Cho, J.H.;Chen, Y.J.;Kim, H.J.;Yoo, J.S.;Lee, C.Y.;Park, B.C.;Lee, J.H.;Kim, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.7
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    • pp.1038-1042
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    • 2009
  • Fifty-four cross-bred ((Landrace${\times}$Yorkshire)${\times}$Duroc) pigs (13.47${\pm}$0.03 kg average initial BW) were evaluated in a 42 d growth assay to determine the effects of the fermented soy product (FSP). The dietary treatments were: FSP 0 (corn-soybean basal diet), FSP 2.5 (FSP 0 amended with 2.5% FSP), and FSP 5 (FSP 0 amended with 5% FSP). The body weight at the end of the experiment increased linearly (p = 0.05) as the FSP levels in the diets increased. In addition, the ADG and G/F ratio also increased (linear effect, p = 0.06) as the levels of FSP increased. However, there was no effect of FSP on ADFI or DM digestibility (p>0.05). Furthermore, the N digestibility increased as the FSP levels increased (linear effect, p = 0.003), although the total protein concentration in the blood was not affected by FSP (p>0.05). Additionally, the albumin concentration was higher in pigs fed diets that contained 2.5% FSP than in pigs in the control group or the FSP 5 group (quadratic effect, p = 0.07). The creatinine concentrations were also evaluated at d 42 and found to be greater in pigs that received the FSP 2.5 diet (quadratic effect, p = 0.09). Moreover, the creatinine concentration increased linearly in response to FSP treatment (p = 0.09). Finally, although the BUN concentration on the final day of the experiment was greater in pigs that received the FSP 2.5 diet (quadratic effect, p = 0.10), there were no incremental differences in BUN concentrations among groups (p>0.05). Taken together, the results of this study indicate that feeding FSP to pigs during the late nursery phase improves growth performance and N digestibility.

Influence of Sustain Voltage on Wall Charge and Wall Voltage Characteristics in AC-PDPs

  • Kim, T.Y.;Cho, T.S.;Kim, S.S.;Cho, D.S.;Kim, J.G.;Ahn, J.C.;Jung, Y.H.;Lim, J.Y.;Jung, J.M.;Ko, J.J.;Kim, D.I.;Lee, C.W.;Seo, Y.;Cho, G.S.;Choi, E.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2000.01a
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    • pp.119-120
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    • 2000
  • Influences of sustain voltage on wall charges and wall voltages are experimentally investigated in surface AC plasma display panels(AC-PDPs), in which electrode gap and width are $80\;{\mu}m$ and $270\;{\mu}m$, respectively. The filling gas is Ne-Xe gas mixture, and total pressures 300 Torr. Also it is found that the more amount of Xe mixing ratio makes the less wall charge and voltage for sustain voltage ranged from 140 V to 222 V. The response time has been delayed by adding a small amount of Xe to Ne in comparison with that without Xe. It is also found that the wall charge and voltage are reduced by adding a small amount of Xe to Ne in comparison with those without Xe.

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Characteristics of Undrained Cyclic Shear Behavior for the Nak-dong River Sand Due to the Aging Effect (Aging 효과에 따른 낙동강 모래의 비배수 반복전단거동 특성)

  • Kim Dae-Man;Kim Young-Su;Jung Sung-Gwan;Seo In-Shik
    • Journal of the Korean Geotechnical Society
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    • v.21 no.8
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    • pp.13-26
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    • 2005
  • It was known that the aging effect of sands is insignificant in comparison with clays, and hence the study on this effect had seldom been performed prior to the early 1980s. However, field tests for this effect have been actively carried out since it was investigated that penetration resistance of reformed sands increased with the lapse of time. Recently, the aging effect of sands has also been examined in laboratory testings. In this study, undrained static triaxial tests were performed to evaluate the effect on the Nak-dong River sands, with different .elative densities $(D_r)$, consolidation stress ratios $(K_c)$, and consolidation times. As a result of the tests, it was proved that the undrained cyclic shear strength $(R_f)$ increased with the aged time on the sands. The in situ range of Rf on the sands, which is applicable to the magnitude of earthquake in the Nak-dong River area, was proposed by using the test results.