• Animal Bioscience
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• v.37 no.2
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• pp.193-202
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• 2024

Objective: Oxidative stress (OS) is a pathological process arising from the excessive production of free radicals in the body. It has the potential to alter animal gene expression and cause damage to the jejunum. However, there have been few reports of changes in the expression of long noncoding RNAs (lncRNAs) in the jejunum in piglets under OS. The purpose of this research was to examine how lncRNAs in piglet jejunum change under OS. Methods: The abdominal cavities of piglets were injected with diquat (DQ) to produce OS. Raw reads were downloaded from the SRA database. RNA-seq was utilized to study the expression of lncRNAs in piglets under OS. Additionally, six randomly selected lncRNAs were verified using quantitative real-time polymerase chain reaction (qRT-PCR) to examine the mechanism of oxidative damage. Results: A total of 79 lncRNAs were differentially expressed (DE) in the treatment group compared to the negative control group. The target genes of DE lncRNAs were enriched in gene ontology (GO) terms and Kyoto encyclopedia of genes and genomes (KEGG) signaling pathways. Chemical carcinogenesis-reactive oxygen species, the Foxo signaling pathway, colorectal cancer, and the AMPK signaling pathway were all linked to OS. Conclusion: Our results demonstrated that DQ-induced OS causes differential expression of lncRNAs, laying the groundwork for future research into the processes involved in the jejunum's response to OS.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.1
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• pp.85-93
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• 2024

In this study, we prepared fractions from Cynanchum paniculatum (C. paniculatum) with ethyl acetate and identified the structure and content of paeonol, an indicator substance. Fractions were obtained by sequential solvent fractions using n-hexane, methylene chloride, ethyl acetate, n-butanol, and distilled water, and showed the highest paeonol content in ethyl acetate (EtOAc). The structure of the ethyl acetate fraction (EA) was confirmed by nuclear magnetic resonance (NMR) and the content was determined by high performance liquid chromatography (HPLC) analysis. The antioxidant activity of EA was tested through its ability to scavenge 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and its ability to inhibit nitric oxide (NO) production in RAW 264.7 cells induced by lipopolysaccharide (LPS) was tested for its ability to inhibit NO production in a concentration-dependent manner. Furthermore, MMP-1 production induced by ultraviolet B (UVB) was decreased in a concentration-dependent manner by the EA, and the ability to produce procollagen type-I was increased in a concentration-dependent manner. In addition, as a result of conducting clinical trials using cosmetic formulations containing EA, the effect of improving wrinkles around the eyes was confirmed. Thus, it is expected that Cynanchum paniculatum can be used as a natural functional cosmetic material with antioxidant and anti-aging effects.

• Journal of the Economic Geographical Society of Korea
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• v.27 no.1
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• pp.18-37
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• 2024

This study examines migrant workers' occupational health and safety issues through a case study of the UK construction industry, focusing on structural vulnerabilities. Migrant workers are at the bottom of the hierarchically fragmented labour market, performing outsourced hazardous work. Structural vulnerability focuses on the social structures that create hierarchies and increase risk in the workplace, rather than on individual responsibility or 'cultural' differences of migrant workers. The study considers the structural factors that perpetuate the migrantisation of risk in the UK construction industry, focusing on the structural necessity of low-wage migrant labour, precarious employment and the legal status of migrant workers, and discusses how these three factors interact to increase migrant workers' vulnerability to health and safety. The migrantisation of risk is not only a matter of occupational health and safety or universal workers' compensation, but also of the intertwining of labour migration policies with employment structures that rely on low-wage, low-skilled labour. This calls for proactive measures to address structural risks that go beyond passive declaratory policies that do not exclude migrant workers from education, training or legal systems.

• Knowledge Management Research
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• v.25 no.1
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• pp.1-19
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• 2024

This study analyzed the changes in social media reactions of data subjects to major personal data breach incidents in South Korea from January 2014 to October 2022. We collected a total of 1,317 posts written on Naver Blogs within a week immediately following each incident. Applying the LDA topic modeling technique to these posts, five main topics were identified: personal data breaches, hacking, information technology, etc. Analyzing the temporal changes in topic distribution, we found that immediately after a data breach incident, the proportion of topics directly mentioning the incident was the highest. However, as time passed, the proportion of mentions related indirectly to the personal data breach increased. This suggests that the attention of data subjects shifts from the specific incident to related topics over time, and interest in personal data protection also decreases. The findings of this study imply a future need for research on the changes in privacy awareness of data subjects following personal data breach incidents.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.379-386
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• 2024

The purpose of this study was to pay attention to the increase in the frequency of expression of butterflies and insects, whose decrease in the number of individuals is symbolized as a measure of environmental pollution, among the various motifs of nature as we go through the COVID-19, when we realized the importance of nature. The scope of this study was limited to fashion collection fashion show photos and interview articles of online for fashion collections from 2019 to 2023. As a result of the study, 185 butterfly motivation fashion design appeared, and digital printing techniques were the most used as a type of plane expression method. Along with this, techniques such as quilting, embroidery, and beading have appeared a lot as techniques to express the planar motif of butterflies. As for the three-dimensional expression types, 3D printing, laser cutting, corsage techniques, and draping techniques showed similar proportion. It can be seen that the expressed butterfly motif had more realistic description the shape of the butterfly as it was than abstract expressions. In conclusion, it can be seen that the butterfly motif fashion design over the past five years contains a stronger message about the environment than the butterfly motif fashion in the past. It was confirmed that it is a motif with a great symbolic meaning that can convey an eco-friendly message beyond just the morphological beauty and colorful design elements of the butterfly.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.484-491
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• 2023

Maize is one of the major crops consumed in worldwide, which nutrients accounts for a large amount of starch, but also functional components, and phenolic acid is known to have a high content. Maize is divided into waxy maize, sweet maize, and normal maize with its shape and use, therefore there is also a difference in nutritional composition. This study was conducted to analyze the content of functional components according to the type of maize and to produce natural variation data in consideration of environmental factors. 3 shapes of maize (waxy maize, sweet maize, and normal maize) samples cultivated in 3 regions (Suwon, Daegu, and Hongcheon) were analyzed using HPLC and GC-TOF-MS. Comparing with type through ANOVA, multivariate statistical analysis, Pearson correlation analysis, 28 components, including carotenoids and tocopherols, showed significant differences among a total of 32 components (p <0.05), 15 of them showed very significant differences (p <0.001). When comparing with regions, 15 components showed significant differences and only vanillate, syringate, C23-ol of them showed most significant differences (p <0.001). As a result of principal component analysis, cluster classification was distinguished by shape than by region, with α-carotene, cholesterol for waxy maize, vanillate and stigmasterol for sweet maize, lutein and β-carotene for normal maize had a great effect on cluster formation. It suggests that the content of functional components is more affected by genetic factors than environmental factors.

• Journal of Microbiology and Biotechnology
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• v.34 no.3
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• pp.606-621
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• 2024

This study evaluated the hepatoprotective effect of fermented Protaetia brevitarsis larvae (FPB) in ethanol-induced liver injury mice. As a result of amino acids in FPB, 18 types of amino acids including essential amino acids were identified. In the results of in vitro tests, FPB increased alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities. In addition, FPB treatment increased cell viability on ethanol- and H₂O₂-induced HepG2 cells. FPB ameliorated serum biomarkers related to hepatoxicity including glutamic oxaloacetic transaminase, glutamine pyruvic transaminase, total bilirubin, and lactate dehydrogenase and lipid metabolism including triglyceride, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. Also, FPB controlled ethanol metabolism enzymes by regulating the protein expression levels of ADH, ALDH, and cytochrome P450 2E1 in liver tissue. FPB protected hepatic oxidative stress by improving malondialdehyde content, reduced glutathione, and superoxide dismutase levels. In addition, FPB reversed mitochondrial dysfunction by regulating reactive oxygen species production, mitochondrial membrane potential, and ATP levels. FPB protected ethanol-induced apoptosis, fatty liver, and hepatic inflammation through p-AMP-activated protein kinase and TLR-4/NF-κB signaling pathways. Furthermore, FPB prevented hepatic fibrosis by decreasing TGF-β1/Smad pathway. In summary, these results suggest that FPB might be a potential prophylactic agent for the treatment of alcoholic liver disease via preventing liver injury such as fatty liver, hepatic inflammation due to chronic ethanol-induced oxidative stress.

• Food Science and Preservation
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• v.31 no.3
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• pp.444-451
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• 2024

This study aimed to investigate the characteristics of protein hydrolysates derived from defatted egg yolk using various proteolytic enzymes and compare the antioxidant activity of the resulting hydrolysates. The defatted egg yolk powder was subjected to enzymatic hydrolysis using four different proteases (alcalase, bromelain, flavourzyme and neutrase), and the resulting hydrolysates were evaluated for their antioxidant properties. Through analysis of available amino group contents and sodium dodecyl sulfate-polyacrylamide gel electrophoresis, it was observed that the defatted egg yolk powder treated with alcalase, flavourzyme, and neutrase for 12 h exhibited a high degree of hydrolysis value. Based on the RC₅₀ values obtained from two different antioxidant analyses, all hydrolysates showed comparable antioxidant activity, except for the alcalase hydrolysate, which demonstrated notably higher scavenging activity against hydrogen peroxide than the other hydrolysates. These findings suggest the potential of protein hydrolysates from defatted egg yolk, a by-product of lecithin extraction, as natural antioxidants.

• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.331-337
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• 2024

The laws and regulations governing the operation of government committees in Korea provide for a system called exclusion. Exclusion is a system that excludes a member of a committee from deliberating or voting on a matter or agenda without having to go through a special procedure before deliberating or voting on the matter or agenda. This is because exclusion of a member from deliberation and voting is not only essential for the protection of the interests of the parties to the issue or matter and the peaceful resolution of disputes, but is also a very important value for the trust in the fairness of the process. However, in practice, it is not easy to determine that a member who has a reason for disqualification is naturally incapable of executing the duties of the matter or agenda just because he or she has a reason for disqualification. Prior to the overhaul of the disqualification rules for committee members in the statutes, it is necessary to eliminate the disqualification rules that are virtually dead in advance or to revise the rules that are difficult to determine without interpretation, contrary to the intention of the disqualification rules that are codified in the law. Therefore, this study analyzed the disqualification rules of nine committees in the domestic statutes (laws and enforcement regulations) and categorized the disqualification rules. We hope to contribute to the preparation of future legislative proposals to improve the rules on the exclusion of commissioner.

• Journal of Positioning, Navigation, and Timing
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• v.13 no.3
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• pp.257-268
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• 2024

The Korea Augmentation Satellite System (KASS) satellite was successfully launched and service is being started. By receiving messages transmitted from the KASS satellite, users can employ the messages to improve positioning accuracy or to verify the integrity of Global Positioning System (GPS). In this paper, we propose a test method for a beam-formed GPS receiver developed to improve the survivability of KASS augmented messages that can enhance positioning accuracy even in an environment with jamming or interfering signals. Through the test method proposed in this paper, quantitative verification is performed for a beam-formed GPS receiver aimed at maintaining the augmented navigation solution to which KASS augmented messages are applied by tracking the KASS signal as much as possible under conditions where the jamming signal strength is gradually increasing. In addition, the proposed test method includes three conditions; first, a static lab test method for repeated verification of functions under the same conditions; second, a static outdoor test method for performance verification in an operating environment of a platform equipped with the beam-formed GPS receiver; and finally, a dynamic lab test method for performance verification of a moving platform equipped with the beam-formed GPS receiver toward a jammer. In this paper, we propose a method for simulating the jamming signal incident direction through the phase delay of an RF cable designed to prevent unintentional jamming signal emission in both lab and outdoor tests, and a method of applying test software for injecting a jamming signal to compare the survivability performance consistently according to the presence or absence of beamforming signal processing. Through the proposed test method, it was verified that the augmented navigation solution could be output for a longer time period when the beamforming signal processing was applied to the KASS satellite signal in the beam-formed GPS receiver.