• Title/Summary/Keyword: $pH_u$

Search Result 1,698, Processing Time 0.023 seconds

POSITIVE SOLUTIONS TO p-KIRCHHOFF-TYPE ELLIPTIC EQUATION WITH GENERAL SUBCRITICAL GROWTH

  • Zhang, Huixing;Zhang, Ran
    • Bulletin of the Korean Mathematical Society
    • /
    • v.54 no.3
    • /
    • pp.1023-1036
    • /
    • 2017
  • In this paper, we study the existence of positive solutions to the p-Kirchhoff elliptic equation involving general subcritical growth $(a+{\lambda}{\int_{\mathbb{R}^N}{\mid}{\nabla}u{\mid}^pdx+{\lambda}b{\int_{\mathbb{R}^N}{\mid}u{\mid}^pdx)(-{\Delta}_pu+b{\mid}u{\mid}^{p-2}u)=h(u)$, in ${\mathbb{R}}^N$, where a, b > 0, ${\lambda}$ is a parameter and the nonlinearity h(s) satisfies the weaker conditions than the ones in our known literature. We also consider the asymptotics of solutions with respect to the parameter ${\lambda}$.

Structure-Activity Relationships of Dimethylsphingosine (DMS) Derivatives and their Effects on Intracellular pH and $Ca^{2+}$ in the U937 Monocyte Cell Line

  • Chang, Young-Ja;Lee, Yun-Kyung;Lee, Eun-Hee;Park, Jeong-Ju;Chung, Sung-Kee;Im, Dong-Soon
    • Archives of Pharmacal Research
    • /
    • v.29 no.8
    • /
    • pp.657-665
    • /
    • 2006
  • We recently reported that dimethylsphingosine (DMS), a metabolite of sphingolipids, increased intracellular pH and $Ca^{2+}$ concentration in U937 human monocytes. In the present study, we found that dimethylphytosphingosine (DMPH) induced the above responses more robustly than DMS. However, phytosphingosine, monomethylphytosphingosine or trimethylsphingosine showed little or no activity. Synthetic C3 deoxy analogues of sphingosine did show similar activities, with the C16 analogue more so than C18. The following structure-activity relationships were observed between DMS derivatives and the intracellular pH and $Ca^{2+}$ concentrations in U937 monocytes; 1) dimethyl modification is important for the DMS-induced increase of intracellular pH and $Ca^{2+}$, 2) the addition of an OH group on C4 enhances both activities, 3) the deletion of the OH group on C3 has a negligible effect on the activities, and 4) C16 appears to be more effective than C18. We also found that W-7, a calmodulin inhibitor, blocked the DMS-induced pH increase, whereas, KN-62, ML9, and MMPX, specific inhibitors for calmodulin-dependent kinase II, myosin light chain kinase, and $Ca^{2+}$-calmodulin-dependent phosphodiesterase, respectively, did not affect DMS-induced increases of pH in the U937 monocytes.

Use of Lysozyme as a Feed Additive on In vitro Rumen Fermentation and Methane Emission

  • Biswas, Ashraf A.;Lee, Sung Sill;Mamuad, Lovelia L.;Kim, Seon-Ho;Choi, Yeon-Jae;Bae, Gui-Seck;Lee, Kichoon;Sung, Ha-Guyn;Lee, Sang-Suk
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.29 no.11
    • /
    • pp.1601-1607
    • /
    • 2016
  • This study was conducted to determine the effect of lysozyme addition on in vitro rumen fermentation and to identify the lysozyme inclusion rate for abating methane ($CH_4$) production. An in vitro ruminal fermentation technique was done using a commercial concentrate to rice straw ratio of 8:2 as substrate. The following treatments were applied wherein lysozyme was added into 1 mg dry matter substrate at different levels of inclusion: Without lysozyme, 2,000, 4,000, and 8,000 U lysozyme. Results revealed that, lysozyme addition had a significant effect on pH after 24 h of incubation, with the highest pH (p<0.01) observed in 8,000 U lysozyme, followed by the 4,000 U, 2,000 U, and without lysozyme. The highest amounts of acetic acid, propionic acid (p<0.01) and total volatile fatty acid (TVFA) (p<0.05) were found in 8,000 U after 24 h of incubation. The $CH_4$ concentration was the lowest in the 8,000 U and the highest in the without lysozyme addition after 24 h of incubation. There was no significant differences in general bacteria, methanogen, or protozoan DNA copy number. So far, addition of lysozyme increased the acetate, propionate, TVFA, and decreased $CH_4$ concentration. These results suggest that lysozyme supplementation may improve in vitro rumen fermentation and reduce $CH_4$ emission.

pH가 메조포러스 탄소의 톨루엔 흡착에 미치는 영향

  • Son, U-Jeong;Chu, Heon-Jik;Kim, Yun-Gap;Choe, Seong-U
    • Proceedings of the Korean Environmental Sciences Society Conference
    • /
    • 2006.11a
    • /
    • pp.153-155
    • /
    • 2006
  • 메조포러스 탄소의 톨루엔 흡착은 peak가 사전실험을 거쳐 조사된 Reference에 도달함에 의해 파과되는 것을 확인하였다. pH와 촉매의 함량을 달리하여 제조한 메조포러스 탄소를 이용한 톨루엔의 흡착실험에서 MC50-6, MCl00-6, MC100-7, MC50-7의 순으로 파과됨을 나타내었다. 톨루엔 흡착에 효율적인 합성조건은 촉매보다는 pH에 따라 달리 제조된 메조포러스 카본이 우수함을 보여주었다.

  • PDF

Adsorption Properties of Uranium on Acrylic Fibers Treated with Hydroxylamine (하이드록실 아민으로 처리한 아크릴 섬유의 우라늄 흡착특성)

  • Chin Young Gil;Lee Jung Sook
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.14 no.2
    • /
    • pp.98-103
    • /
    • 1990
  • Fibrous adsorbents containing amidoxime group which make chelate complexes with uranyl ions are studied for the recovery of uranium from sea water. Acrylic fibers are used as base Polymer. The adsorption properties of uranium are carried out to examine pH effect, concen-tration dependence, adsorption rate, separation, and chelate complex. The results obtained are as follows; 1. Metal capacity of U (VI) ion is in the range of pH $2\~10.2$. Amidoxime group-containing fiber recover U (VI) ions existed in sea water or waste water in extremely small quantities. 3. Using amidoxime group-containing fiber Cu (II) and U (VI) are separated with each other in dilute nitric acid solution (pH 2.3). 4. U (VI) chelate complexes are conformed by tridendate ligands, which are coordinated with one nitrogen and two oxygens onto amidoxime group-containing fiber.

  • PDF

A Chelating Resin Containing 2-(2-Thiazolylazo)-5-dimethylaminophenol as the Functional Group: Synthesis and Sorption Behavior for Some Trace Metal Ions

  • Lee, Won;Lee, Si-Eun;Kim, Mi-Kyoung;Lee, Chang-Heon;Kim, Young-Sang
    • Bulletin of the Korean Chemical Society
    • /
    • v.23 no.8
    • /
    • pp.1067-1072
    • /
    • 2002
  • A new polystyrene-divinylbenzene resin containing 2-(2-thiazolylazo)-5-dimethylamino-phenol (TAM) functional groups has been synthesized and its sorption behavior for nineteen metal ions, including Zr(Ⅳ),Hf(Ⅳ) and U(Ⅵ) has been investigated by batch and column methods. The chelating resin showed high sorption affinity for Zr(Ⅳ) at pH 1-5 and U(Ⅵ) at pH 4. Some parameters affecting the sorption of the metal ions have been detailed. The breakthrough and overall capacities were measured under optimized conditions. The overall capacities of Zr(Ⅳ), Th(Ⅳ) and U(Ⅵ), which showed higher than the other metal ions, were 0.90,0.84 and 0.80 mmol/g, respectively. The elution order of metal ions at pH 4 was evaluated as Zr(Ⅳ) > Th(Ⅳ) > U(Ⅵ) > Cu(Ⅱ) > Hf(Ⅳ) > W(Ⅵ) > Mo(Ⅵ) > In(Ⅲ) > Sn(Ⅳ) > Cr(Ⅲ) > V(Ⅴ) > Fe(Ⅲ). Quantitative recovery of most metal ions except Zr(Ⅳ) was achieved using 2M HNO3. Desorption and recovery of Zr(Ⅳ) was successfully performed with 2 M HClO4 and 2 M HCl.

Characteristics of Technical Meat Quality Parameters & Carcass Traits between the PSE and Normal Pork Classified by Conductance Threshold (전기전도도 기준에 의한 PSE육과 정상육의 육질 및 도체 특성에 관한 연구)

  • 김동훈;이무하;이제룡;박범영;유영모;이종문;김용곤
    • Food Science of Animal Resources
    • /
    • v.18 no.3
    • /
    • pp.248-254
    • /
    • 1998
  • The two hundreds and twenty two pork carcasses from commercial breed were tested to compare technical quality characteristics and relationships with meat quality parameters between PSE and normal pork classified buy 24hr postmortem conductivity($C_u$). In characteristics of PSE and normal pork by $C_u$ value, highly significant differences were found in NPPC color scale and CIE L*(p<0.001), moderately significant differences in $C_3$ and cooking loss(p<0.01), and significant differences were in $C_6$, CIE b*, WHC and juiciness(p<0.05). In correlation coefficients between $C_u$ and other meat quality determining factors, $C_u$ was poorly related with $pH_1$($R^2$=0.28, p<0.001), CIE a*($R^2$=0.14, p<0.05), b*($R^2$=0.28, p<0.01) and cooking loss($R^2$=0.26, p<0.01). Also, relatively low correlation coefficients were observed in $pH_u$($R^2$=0.32, p<0.001), WHC($R^2$=0.39, p<0.001) and juiciness($R^2$=0.41, p<0.001). Moderately high coefficients were found in NPPC color scale($R^2$=0.59, p<0.001) and CIE L*($R^2$=0.58, p<0.001).

  • PDF

Isolation and Identification of Alkalophilic Microorganism and its Mutant Growing at Neutral pH (호알칼리성 미생물의 분리, 동정 및 중성에서 생육 가능한 변이주의 분리)

  • 심창환;신원철;유주현
    • Microbiology and Biotechnology Letters
    • /
    • v.19 no.6
    • /
    • pp.543-547
    • /
    • 1991
  • An alkalophilic microorganism, SH-8, was isolated from soil samples. It was a Grampositive, catalase-positive, spore-forming and motile rod which was capable of growth in aerobic condition at the initial pH 9.0 or above up to 11.0 and between 15 and $42^{\circ}C$ The characteristics of this strain resembled those of the Bacillus group of bacteria. The mutant, Bacillus sp. SH- 8M, was selected from Bacillus sp. SH-8 by U.V. mutagenesis and was able to grow at pH 6.9 up to 11.0. These two strains will be suitable for the comparative study on growth and enzyme production at various pH conditions.

  • PDF

Developmental Capacity of Mouse Oocytes within Preantral Follicles Cultured in Medium Supplemented with Gonadotroplhins (성선자극호르몬이 첨가된 배양액에서 체외배양된 생쥐 Preantral Follicles 내 난자의 발생능력)

  • Kim, D.H;Kang, H.G.;Kim, M.K.;Han, S.W.;Chi, H.J.;Lee, H.J.;Lee, H.T.;Chung, K.S.
    • Korean Journal of Animal Reproduction
    • /
    • v.24 no.4
    • /
    • pp.395-406
    • /
    • 2000
  • The present study was conducted to examine the developmental capacity of mouse oocytes within prenatal follicles cultured various concentrations of FSH and LH and the expression of cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc) and cytochrome P450 17 $\alpha$ -hydroxylase (P450)$_{17{\alpha}}$ mRNA, as luteinization and atretic marker, in these culture conditions. In addition, we investigated the concentrations of progesterone and testosterone in culture medium. The developmental potential up to blastocyst of the oocytes grown in vitro was higher in the FSH alone (30.2%) and 10 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH treated (28.0%) groups than in the 100 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH treated group (22.0%). And the mean numbers of cell per blastocyst was higher in the FSH alone (50.9$\pm$26.1) and 10 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH treated (51.0$\pm$21.1) groups when compared to the 100 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH treated group (45.2$\pm$15.1). The expressions of P450scc and P450$_{17{\alpha}}$ mRNA in the oocyte -cumulus complexes were increased with increasing of LH concentration, and also the secretions of progesterone and testosterone were increased. Especially, in the 100 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH treated group, the expression of P450scc and P450$_{17{\alpha}}$ were significantly increased, and the secretion of progesterone and testosterone were significantly increased. Therefore, these data show that gonadotrophins are essential for the in vitro culture of preantral follicles, but that increasing of LH concentration is reduced the developmental capacity of oocytes. The cause of these findings may be due to increasing of progesterone and testosterone secretion by the enhance of P450scc and P450$_{17{\alpha}}$ mRNA expressions, as markers of luteinization and atresia. Conclusively, this study suggest that supplementation of 100 $m\ell$U/$m\ell$ FSH or 10 $m\ell$U/$m\ell$ LH and 100 $m\ell$U/$m\ell$ FSH may be optimal condition for the culture of mouse pre antral follicles.

  • PDF

Purification and Characterization of Phospholipase D from Actinomycetes KF923. (방선균 KE923이 생산하는 Phospholipase D의 정제 및 특성)

  • 곽보연;윤석후;김창진;손동화
    • Microbiology and Biotechnology Letters
    • /
    • v.31 no.4
    • /
    • pp.389-394
    • /
    • 2003
  • In order to screen microorganisms producing phopholipase D (PLD) had high transphosphatidylation activity, about 1,000 Actinomycetes strains were isolated from the 63 soil samples, collected over 6 local area in Korea. When the hydrolytic activity in the supernatant was determined, 131 strains produced PLD more than 0.3 U/ml. Among 131 culture broths tested, 23 ones had transphosphatidylation activity higher than 20% and finally one strain (Actinomycetes KF 923), which had highest hydrolytic and transphophadylation activity, was selected. Actinomycetes KF923 showed the highest hydrolytic activity (13 U/ml) and phosphatidylation activity (95%) after 48 h fermentation using the P medium (yeast extract 1%, peptone 1%, glucose 1.5%, glycerol 1%, $CaCo_3$ 0.4%, pH 7.2). PLD was purified from the culture broth of Actinomycetes KF923 and the specific activity of purified PLD was 567 U/mg. The molecular weight of PLD was about 55 kD and the optimum pH and temperature were 6.0 and $60^{\circ}C$, respectively. The stability of PLD toward pH and temperature were high around pH 8.0 and below $40^{\circ}C$. Special metal ions were not necessary to the PLD activity.