• Preventive Nutrition and Food Science
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• v.20 no.1
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• pp.43-51
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• 2015

${\varepsilon}$-Polylysine (EPL) is used as a natural preservative in food. However, few studies have been conducted to assess the beneficial functions of dietary EPL. The purpose of this study was to elucidate the mechanism underlying the inhibition of neutral and acidic sterol absorption and hepatic enzyme activity-related fatty acid biosynthesis following EPL intake. EPL digest prepared using an in vitro digestion model had lower lipase activity and micellar lipid solubility and higher bile acid binding capacity than casein digest. Male Wistar rats were fed an AIN-93G diet containing 1% (wt/wt) EPL or L-lysine. After 4 weeks of feeding these diets, the marked decrease in serum and liver triacylglycerol contents by the EPL diet was partly attributed to increased fecal fatty acid excretion. The activities of hepatic acetyl-coenzyme A carboxylase and glucose-6-phosphate dehydrogenase, which are key enzymes of fatty acid biosynthesis, were enhanced in rats fed EPL diet. The increased fatty acid biosynthesis activity due to dietary EPL may be prevented by the enhancement of fecal fatty acid excretion. The hypocholesterolemic effect of EPL was mediated by increased fecal neutral and acidic sterol excretions due to the EPL digest suppressing micellar lipid solubility and high bile acid binding capacity. These results show that dietary EPL has beneficial effects that could help prevent lifestyle-related diseases such as hyperlipidemia and atherosclerosis.

• Transactions of the KSME C: Technology and Education
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• v.3 no.3
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• pp.233-240
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• 2015

Analysis of the aerodynamic performance of a bobsleigh has been performed for various types of bobsleigh body shape. To analyze the aerodynamic performance of the bobsleigh, three-dimensional Reynolds-averaged Navier-Stoke equations were used with the standard k-${\varepsilon}$ model as a turbulence closure. Grid structure was composed of unstructured tetrahedral grids. The radii of curvature of cowling, and height and length of front bumper at the tip on the drag coefficient were selected as geometric parameters. And, the effects of these parameters on the aerodynamic performance, i.e., the drag coefficient, were evaluated. The results shows that the aerodynamic performance is significantly affected by the height of front bumper and radius of curvature.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.1
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• pp.104-111
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• 2017

This research focuses on simulation and visualization of flow field characteristics inside a centrifugal pump. The 3D numerical analysis was carried out by using a numerical CFD tool, addressing a Reynolds Average Navier-Stock code with a standard k-${\varepsilon}$ two-equation turbulence model. The simulation accounts for friction head loss due to rough walls at suction, impeller, discharge areas and volumetric head loss at impeller wear ring. A comparison of performance curves between simulation and experimentation is included, and it reveals a same trend of those results with a small difference of maximum 5 %. At best efficiency point, velocity vectors are smooth but it changes significantly under off-design point, a strong recirculation appears at the outlet of impeller passages near tongue area. A relatively uniform preassure distribution was observed around the impeller in despite of the tongue. Within the volute, because of its geometry, spiral vortexes formed, proving that the flow field in this region was relatively turbulent and unsteady.

• Journal of Korean Society for Atmospheric Environment
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• v.21 no.5
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• pp.525-535
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• 2005

Using a three-dimensional computational fluid dynamics (CFD) model with the $k-{\varepsilon}$ turbulence closure scheme based on the renormalization group theory, flow regimes in urban street canyons are classified according to the building and street aspect ratios. The transition between skimming flow (SF) and wake interference flow (WIF) is determined with the size of double-eddy circulation generated behind the upwind building. The transition between WIF and isolated roughness flow (IRF) is determined with the flow reattachment distance from the upwind building. The critical aspect ratios at which the flow transition occurs are found and compared with those in previous studies. The results show that the flow-regime classification method used in this study is quite reasonable and that the values of the critical aspect ratios are generally consistent with those in fluid experiments or large-eddy simulation. The regression equation describing a relation between the building and street aspect ratios at the flow-regime transition is presented.

• Journal of Ocean Engineering and Technology
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• v.26 no.1
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• pp.9-16
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• 2012

This paper presents the numerical results of a simulation of the free surface flow around a blunt bow ship model and focuses on the validation of the proposed method with a brief investigation of the relation between the resistance and free surface behavior. A finite volume method based on the Reynolds Averaged Navier-Stokes (RANS) approach is used to solve the governing flow equations, where the free surface, including wave breaking,is captured by using a two-phase Level-Set (LS) method. For turbulence closure, a two equation k-${\varepsilon}$ model with the standard wall function technique is used. Finally, the numerical results are compared with the available experimental data, showing good agreement.

• Journal of Environmental Science International
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• v.15 no.1
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• pp.95-100
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• 2006

Heat transfer and flow characteristics in a pipe in which the rotating cutting tool for boring a underground pipe without digging were considered in this study. The amount of heat generation due to the friction between the rotating cutter and pipe wall, mixing (low of air and water injected to cool down are the two important factors to design the boring machine Computational fluid dynamics analysis using the Eulerian mixture model and the standard $\kappa-\varepsilon$ turbulence model was used to analyze the complex phenomena in a pipe during the process. Results show that pipe wall temperature decreased with increasing the cooling water inlet velocity. it is also shown that pipe wail temperature was lowered when the cutter rotation speed was increased until 600 rpm. There was no further cooling effect over 600 rpm.

• 한국전산유체공학회:학술대회논문집
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• 1998.11a
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• pp.90-95
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• 1998

The two-dimensional incompressible and compressible Navier-Stokes codes are developed for the computation of the viscous turbulent flow over high-lift airfoils. Incompressible code using pseudo-compressibility and dual-time stepping method involves a conventional upwind differencing scheme for the convective terms and LU-SGS scheme for time integration. Compressible code also adopts an FDS scheme and LU-SGS scheme. Several two-equation turbulence models (the standard $k-{\varepsilon}$ model, the $k-{\omega}$ model. and $k-{\omega}$ SST model) are evaluated by computing the flow over single and multi-element airfoils. The compressible and incompressible codes are validated by computing the flow around the transonic RAE2822 airfoil and the NACA4412 airfoil, respectively. Both the results show a good agreement with experimental surface pressure coefficients and velocity profiles in the boundary layers. Also, the GA(W)-1 single airfoil and the NLR7301 airfoil with a flap are computed using the two-equation turbulence models. The grid systems around two- and three-element airfoil are efficiently generated using Chimera grid scheme, one of the overlapping grid generation methods.

• Nuclear Engineering and Technology
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• v.41 no.7
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• pp.907-920
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• 2009

This study was performed to evaluate the prediction capability of a commercial CFD code and to investigate the effects of different geometries such as a 4.4 mm tube and an 8/10 mm annular channel on the detailed flow structures. A numerical simulation was performed for the conditions, at which the experimental data was produced by the test facility SPHINX. A 2-dimensional axisymmetric steady flow was assumed for computational simplicity. The RNG $\kappa-\varepsilon$ turbulence model (RNG) with an enhanced wall treatment option, SST $\kappa-\omega$ (SST) and low Reynolds Abid turbulence model (ABD) were employed and the numerical predictions were compared with the experimental data generated from the experiment. The effects of the geometry on heat transfer were investigated. The flow and temperature fields were also examined in order to investigate the mechanism of heat transfer near the wall. The local heat transfer coefficient predicted by the RNG model is very close to the measurement result for the tube. In contrast, the local heat transfer coefficient predicted by the SST and ABD models is closer to the measurement for the annular channel.

• Journal of Biomedical Engineering Research
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• v.34 no.3
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• pp.111-116
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• 2013

Finite element analysis(FEA) has been extensively applied in the analyses of biomechanical properties of stents. Geometrically, a closed-cell stent is an assembly of a number of repeated unit cells and exhibits periodicity in both longitudinal and circumferential directions. This study concentrates on various parameters of the FEA models for the analysis of drug-eluting biodegradable polymeric stents for application to the treatment of coronary artery disease. In order to determine the mechanical characteristics of biodegradable polymeric stents, FEA was used to model two different types of stents: tubular stents(TS) and helicoidal stents(HS). For this modeling, epigallocatechin-3-O-gallate (EGCG)-eluting poly[(L-lactide-co-${\varepsilon}$-caprolactone), PLCL] (E-PLCL) was chosen as drug-eluting stent materials. E-PLCL was prepared by blending PLCL with 5% EGCG as previously described. In addition, the effects of EGCG blending on the mechanical properties of PLCL were investigated for both types of stent models. EGCG did not affect tensile strength at break, but significantly increased elastic modulus of PLCL. It is suggested that FEA is a cost-effective method to improve the design of drug-eluting biodegradable polymeric stents.

• Journal of the Korean Geosynthetics Society
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• v.14 no.1
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• pp.11-21
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• 2015

This study aims at investigating of the behavioral characteristics of foundation ground subjected to a strip load in anisotropy. Using marine clays sampled at Shihwa area, a series of laboratory tests including triaxial compressive test, plane strain compressive and expansion tests that allows horizontal deformation only and zero strain (${\varepsilon}_2$) in the direction of intermediate stress (${\sigma}_2$) are conducted. In addition, a numerical analysis using parameters obtained from the tests is carried out. In the numerical analysis, Cam-clay model that simulates the behavior of natural deposited clay properly is adopted. The analysis results show that the vertical displacements of the plane strain compressive tests are relatively larger than those of triaxial compressive tests by 18-25%. Likewise, the horizontal displacements is 13-19% larger.