• Nutrition Research and Practice
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• v.9 no.6
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• pp.606-612
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• 2015

BACKGROUND/OBJECTIVES: Several medicinal properties of Smilax china L. have been studied including antioxidant, anti-inflammatory, and anti-cancer effects. However, the antiobesity activity and mechanism by which the water-soluble fraction of this plant mediates its effects are not clear. In the present study, we investigated the lipolytic actions of the water-soluble fraction of Smilax china L. leaf ethanol extract (wsSCLE) in 3T3-L1 adipocytes. MATERIALS/METHODS: The wsSCLE was identified by measuring the total polyphenol and flavonoid content. The wsSCLE was evaluated for its effects on cell viability, lipid accumulation, glycerol, and cyclic adenosine monophosphate (cAMP) contents. In addition, western blot analysis was used to evaluate the effects on protein kinase A (PKA), PKA substrates (PKAs), and hormone-sensitive lipase (HSL). For the lipid accumulation assay, 3T3-L1 adipocytes were treated with different doses of wsSCLE for 9 days starting 2 days post-confluence. In other cell experiments, mature 3T3-L1 adipocytes were treated for 24 h with wsSCLE. RESULTS: Results showed that treatment with wsSCLE at 0.05, 0.1, and 0.25 mg/mL had no effect on cell morphology and viability. Without evidence of toxicity, wsSCLE treatment decreased lipid accumulation compared with the untreated adipocyte controls as shown by the lower absorbance of Oil Red O stain. The wsSCLE significantly induced glycerol release and cAMP production in mature 3T3-L1 cells. Furthermore, protein levels of phosphorylated PKA, PKAs, and HSL significantly increased following wsSCLE treatment. CONCLUSION: These results demonstrate that the potential antiobesity activity of wsSCLE is at least in part due to the stimulation of cAMP-PKA-HSL signaling. In addition, the wsSCLE-stimulated lipolysis induced by the signaling is mediated via activation of the ${\beta}$-adrenergic receptor.

• Journal of Convergence for Information Technology
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• v.9 no.12
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• pp.47-53
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• 2019

The purpose of the study was to utilize VECM(Vector Error Correction Model) and detect causal relationships among shipping freight rates. Shipping freight rates used in this study were BDI(Baltic Dry Index), HRCI(Howe Robinson Containership Index), WS(World Scale rate) and SCFI(Shanghai Containerized Freight Index). Using weekly data published since August 2nd, 2013 to September 6th, 2019, it was discovered that BDI and WS were heavily influenced by past week's BDI and WS respectively. VECM also found that one percent increase in WS resulted in 0.022% increase in following week's HRCI data. One percent increase in HRCI affects SCFI by 0.77% on the following week. This study believes that finding may help each shipping market of shipping freight rates estimates, thereby encouraging decision markers to exercise discretion and establish best interest decision.

• The Journal of Internal Korean Medicine
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• v.26 no.1
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• pp.48-59
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• 2005

Objectives : The aim of the study was to evaluate the effect of WS on HepG2 cell cycle and expression of related genes. Methods : The MTT assay, Cell counting analysis, $[^3H]-Thymidine$ Incorporation Assay, Flow cytometric analysis, Quantitative RT-PCR were studied. Results : WS inhibited HepG2 cell proliferation in low concentration$(1-10\;{\mu]g/ml)$ which did not cause direct cytotoxicity, with dose-dependant manner. WS in-hibited DNA synthesis as well. Flow cytometric analysis on the HepG2 cell showed G2/M phase arrest. Conclusion : These results suggest that WS inhibits HepG2 cell proliferation not by the gene regulation but by G2/M phase arrest in the cell cycle. Thus further studies on the effect of WS in G2/M phase regulation are thought to be needed.

• Tribology and Lubricants
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• v.25 no.1
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• pp.61-65
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• 2009

Tribological properties of the semi-metallic friction materials containing different solid lubricants (graphite, $WS_2$, $MoS_2$) were investigated. The friction materials were fabricated with an experimental formulation and tested with gray cast iron disks. Results showed that graphite contributed to stabilize the friction coefficient during run-in processes. Also, graphite provided better fade resistance than that of $WS_2$ and $MoS_2$. At intermediate temperature ranges, however, friction materials with $WS_2$ or $MoS_2$ maintained higher friction effectiveness than that of graphite. On the other hand, friction materials containing $MoS_2$ showed increased wear rates than that with graphite or $WS_2$. Friction materials with proper combinations of two solid lubricants showed better friction and wear properties than that of the friction materials containing single solid lubricant.

• Journal of the Semiconductor & Display Technology
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• v.17 no.3
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• pp.31-35
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• 2018

Tungsten disulfide($WS_2$) thin films were directly deposited by direct-current(DC) sputtering and annealed by rapid thermal processing(RTP) to materialize two-dimensional p-type transition metal dichalcogenide (TMDC) thin films on soda-lime glass substrates without any complicated exfoliation/transfer process. $WS_2$ thin films deposited at various DC sputtering powers from 80 W to 160W were annealed at different temperatures from $400^{\circ}C$ to $550^{\circ}C$ considering the melting temperature of soda-lime glass. The optical microscope results showed the stable surface morphologies of the $WS_2$ thin films without any defects. The X-ray photoelectron spectroscopy (XPS) results and the Hall measurement results showed stable binding energies of W and S and high carrier mobilities of $WS_2$ thin films.

• Applied Microscopy
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• v.50
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• pp.27.1-27.6
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• 2020

Transition metal dichalcogenides (TMD), which is composed of a transition metal atom and chalcogen ion atoms, usually form vacancies based on the knock-on threshold of each atom. In particular, when electron beam is irradiated on a monolayer TMD such as MoS₂ and WS₂, S vacancies are formed preferentially, and they are aligned linearly to constitute line defects. And then, a hole is formed at the point where the successively formed line defects collide, and metal clusters are also formed at the edge of the hole. This study reports a process in which the line defects formed in a monolayer WS₂ sheet expends into holes. Here, the process in which the W cluster, which always occurs at the edge of the formed hole, goes through a uniform intermediate phase is explained based on the line defects and the formation behavior of the hole. Further investigation confirms the atomic structure of the intermediate phase using annular dark field scanning transition electron microscopy (ADF-STEM) and image simulation.

• Journal of Korea Foresty Energy
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• v.17 no.1
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• pp.8-22
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• 1998

The phytomass and productivity of the evergreen needle pines(Pinus densiflora and Pinus rigida) and of the deciduous broad- leaved oaks(Quercus acutissima, Quercus variabililis and Quercus mongolica) in the watershed forests of South Han River, central part of Korea was estimated by the allometry. The allometic relations between D$^2$H and dry weight of stem(Ws), branches(Wb) and leaves(Wl) of these forests were as follows: Pinus densiflora community : logWs=0.58482D$^2$H-0.42417 logWb=0.6234D$^2$H-1.2321 logWl=0.2247D$^2$H-0.09359 Pinus rigida community : logWs=0.9218D$^2$H-1.4692 logWb=1.0064D$^2$H-2.2278 logWl=0.6275D$^2$H-1.1715 Quercus acutissima community : logWs=0.96659D$^2$H-1.56975 logWb=0.86315D$^2$H-2.17944 logWl=0.79876D$^2$H-1.97137 Quercus variabilis community : logWs=0.4753D$^2$H＋0.20026 logWb=0.5725D$^2$H-0.92006 logW1=0.61649D$^2$H-1.4288 Quercus momgolica community : logWs=0.5526D$^2$H-0.1228 logWb=0.5188D$^2$H-0.9787 logWl=0.7754D$^2$H-2.6273 From the above formulae, the phytomass of Pinus densiflora was estimated to be much as 1,200,000 ton, Pinus rigida 610,000 ton, Quercus acutissima 289 ton, Quercus variabilis 2,800ton and Quercus mongolica 570,000 ton in the surveyed area, respectively. Accordingly, the phytomass of Pinus densiflora forest was occupied about 43.9 % in toto and was higher thanthose of other forests. The phytomass of watershed forests belonging to Degree 8 and Degree7 divided by degree of green naturality(DGN) was 74,000 ton and 2,000,000 ton, resfectively. Accordingly, the watershed forests in South Han River were mainly composed of Pinus densiflora and Quercus mongolica forests belonging to Degree 7.

• Asian-Australasian Journal of Animal Sciences
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• v.7 no.3
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• pp.413-419
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• 1994

Mold growth decreased nutritive value of wheat straw (WS). Mold increased DM (94 vs 98%) and ADF (51 vs 56%) contents and had no effect on natural detergent fiber (NDF). Crude protein and N values were decreased in moldy wheat straw, Mold increased insoluble N content of wheat straw (WS) from 21 to 27%. Ammoniation increased the CP of nonmoldy straw from 3.8 to 8.3% and moldy straw from (3.3 to 6.2%). Aspergillus and zygomycetes fungal species were most prevalent and total numbers were higher on moldy straw. Ammoniation decreased total numbers of fungal spores on nonmoldy and moldy WS. Ammoniation of moldy WS increased (p < 0.10) feed in take (1.8%) as compared with nonmoldy, ammoniated, nonmoldy and moldy WS. Steers fed moldy WS had lowest (p < 0.10) feed intake (1.3% of BW daily) compared with other diet. There was little difference (p < 0.10) in intake of nonammoniated vs. ammoniated WS. Steers fed moldy straw lost 6 kg BW. Ammoniated, nonmoldy straw elevated Blood Urea Nitrogen (BUN) (10.5 mg/dl). Alkaline Phosphatase (ALK) was greater in steers fed moldy VS nonmoldy straw (148 VS 95 U/liter. p < 0.10).

• Proceedings of the Korean Nuclear Society Conference
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• 1997.05a
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• pp.611-616
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• 1997

The Level 1 probabilistic safety assessment(PSA) for Wolsong(WS) 2/3/4 nuclear power plant(NPPs) in design stage is performed using the methodologies being equivalent to PWR PSA. Accident sequence evaluation program(ASEP) human reliability analysis(HRA) procedure and technique for human error rate prediction(THERP) are used in HRA of WS 2/3/4 NPPs PSA. The purpose of this paper is to introduce the procedure and methodology of HRA in WS 2/3/4 NPPs PSA. Also, this paper describes the interim results of importance analysis for human actions modeled in WS 2/3/4 PSA and the findings and recommendations of administrative control of secondary control area from the view of human factors.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2012.05a
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• pp.324-325
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• 2012

다이아몬드 마이크로 블레이드의 절삭 효율을 향상시키고 소결 공정 중 윤활제의 유동성과 젖음성이 다이아몬드 마이크로 블레이드의 물성에 미치는 영향을 연구하기 위해 Cu/Sn 금속 결합재에 표면을 부식시킨 $WS_2$와 부식을 시키지 않은 $WS_2$ 윤활제를 각각 동일한 체적 분율로 첨가하였다. 윤활제의 표면 개질에 따른 마이크로 블레이드 결합재의 내마모성과 굽힘 강도 시험을 행하였고, 실착 절삭 시험을 위한 마이크로 블레이드 시편을 제작하여 수명 및 효율을 평가하였다. Cu/Sn 금속 결합재 파면에서의 $WS_2$ 입자 방향 분석을 통해 표면 개질 과정을 거친 $WS_2$가 압축소결 공정 중 압축 방향에 수직하게 위치하려는 경향이 크게 나타났으며, 이는 소결체의 강도와 경도를 향상시켰다. 마이크로 블레이드의 절삭 효율 및 수명을 평가하기 위한 실착 절삭 시험 결과, 윤활제 표면 부식처리는 처리하지 않은 경우에 비하여 절삭성능은 비슷하게 관찰되었으나 결합재와의 계면 결함을 줄이므로써 블레이드의 수명을 연장시킬 수 있었다.