• Title/Summary/Keyword: $T_2$ contrast

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A Study on the Image Quality According to the Change of Flip Angle in Flow-Related Enhancement Magnetic Resonance Angiography (유속증강 자기공명혈관조영술에서 숙임각 변화에 따른 영상의 질 연구)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.12 no.2
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    • pp.201-208
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    • 2018
  • The purpose of this study was to investigate the optimal flip angle by measuring the SNR and CNR according to the angle of changes of the MRI technique using the Image J program. A total of 30 normal volunteers were assessed by using a 1.5T magnetic resonance imaging system (Philips, Medical System, Achieva). For the MRI angiography, we set the region of interest in four regions and evaluated the SNR and CNR. The statistical significance of SNR and CNR was calculated by one-way ANOVA using quantitative analysis at five different positions. The Bonferroni method was used for post-hoc analyzes. Statistical significance was determined by using ANOVA analysis at p<0.05 and Bonferroni method was used as a post-hoc analysis. The results of this study, the measurement values of ACA(SNR:$876.59{\pm}14.22$, CNR:$1999.7{\pm}12.5$), PCA(SNR:$863.48{\pm}13.29$, CNR:$1870.18{\pm}12.56$), ICA(SNR:$1116.87{\pm}08.34$, CNR:$2979.37{\pm}14.69$) and MCA(SNR:$848.66{\pm}15.25$, CNR:$2199.25{\pm}13.48$) were obtained with the high signal intensity at $25^{\circ}$(p<0.05). The values of a1, a2, a3, p1, p2, p3, m1, m2 and m3 were also the same (p<0.05). Post-hoc analysis results, There was a statistically significant difference (p=0.000) between $10^{\circ}$, $15^{\circ}$, $20^{\circ}$ on the $25^{\circ}$ reference for the flip angle, but no significant results were obtained with $30^{\circ}$(p<0.05). In concision, because the signal intensity decreased at $30^{\circ}$, this study revealed that the optimal flip angles were $25^{\circ}$ in cerebrovascular MR angiography.

Magnetic Properties of Superparamagnetic Ni-Zn Ferrite for Nano·Bio Fusion Applications (나노·바이오 융합응용을 위한 초상자성 Ni-Zn Ferrite의 자기적 특성연구)

  • Lee, Seung-Wha;Ryu, Yeon-Guk;Yang, Kea-Joon;An, Jung-Su;Kim, Chul-Sung
    • Journal of the Korean Magnetics Society
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    • v.15 no.2
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    • pp.100-105
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    • 2005
  • $Ni_{0.9}Zn_{0.1}Fe_2O_4$ nanoparticles have been prepared by a sol-gel method. The structural and magnetic properties have been investigated by DTA/TGA, XRD, SEM, and $M\ddot{o}ssbauer$ spectroscopy, VSM. $Ni_{0.9}Zn_{0.1}Fe_2O_4$ powder that was annealed at $300^{\circ}C$ has spinel structure and behaved superparamagnetically. The estimated size of superparammagnetic Ni-Zn ferrite nanoparticle is around 10 nm. The hyperfine fields at 13 K for the A and B patterns were found to be 533 and 507 kOe, respectively. The blocking temperature ($T_B$) of superparammagnetic $Ni_{0.9}Zn_{0.1}Fe_2O_4$ nanoparticle is about 250 K. The magnetic anisotropy constant and relaxation time constant of $Ni_{0.9}Zn_{0.1}Fe_2O_4$ nanoparticle were calculated to be $1.6\times10^6\;ergs/cm^3$ and ${\tau}_0=5.0{\times}10^{-13}$ s, respectively. Also, Temperature increased up to $43^{\circ}C$ within 10 minutes under AC magnetic field of 7 MHz. It is considered that $Ni_{0.9}Zn_{0.1}Fe_2O_4$ powder that was annealed at $300^{\circ}C$ is available for biomedicine application such as hyperthermia, drug delivery system and contrast agents in MRI.

Role of p-38 MAP Kinase in apoptosis of hypoxia-induced osteoblasts (저산소 상태로 인한 조골세포 고사사기전에서 p-38 MAP kinase의 역할에 관한 연구)

  • Yoon, Jeong-Hyeon;Jeong, Ae-Jin;Kang, Kyung-Hwa;Kim, Sang-Cheol
    • The korean journal of orthodontics
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    • v.33 no.3 s.98
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    • pp.169-183
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    • 2003
  • Tooth movement by orthodontic force effects great tissue changes within the periodontium, especially by shifting the blood flow in the pressure side and resulting in a hypoxic state of low oxygen tension. The aim of this study is to elucidate the possible mechanism of apoptosis in response to hypoxia in MC3T3El osteoblasts, the main cells in bone remodeling during orthodontic tooth movement. MC3T3El osteoblasts under hypoxic conditions ($2\%$ orygen) resulted in apoptosis in a time-dependent manner as estimated by DNA fragmentation assay and nuclear morphology stained with fluorescent dye, Hoechst 33258. Pretreatment with Z-VAD-FMK, a pancaspase inhibitor, or Z-DEVD-CHO, a specific caspase-3 inhibitor, completely suppressed the DNA ladder in response to hypoxia. An increase in caspase-3-like protease (DEVDase) activity was observed during apoptosis, but no caspase-1 activity (YVADase) was detected. To confirm what caspases are involved in apoptosis, Western blot analysis was performed using anti-caspase-3 or -6 antibodies. The 10-kDa protein, corresponding to the active products of caspase-3, and the 10-kDa protein of the active protein of caspase-6 were generated in hypoxia-challenged cells in which the processing of the full length form of caspase-3 and -6 was evident. While a time course similar to this caspase-3 and -6 activation was evident, hypoxic stress caused the cleavage of lamin A, which was typical of caspase-6 activity. In addition, the stress elicited the release of cytochrome c into the cytosol during apoptosis. Furthermore, we observed that pre-treatment with SB203580, a selective p38 mitogen activated protein kinase inhibitor, attenuated the hypoxia-induced apoptosis. The addition of SB203S80 suppressed caspase-3 and -6-like protease activity by hypoxia up to $50\%$. In contrast, PD98059 had no effect on the hypoxia-induced apoptosis. To confirm the involvement of MAP kinase, JNK/SAPK, ERK, or p38 kinase assay was performed. Although p38 MAPK was activated in response to hypoxic treatment, the other MAPK -JNK/SAPK or ERK- was either only modestly activated or not at all. These results suggest that p38 MAPK is involved in hypoxia-induced apoptosis in MC3T3El osteoblasts.

THE EFFECT OF ORTHODONTIC TREATMENT BY PREMOLAR EXTRACTION ON THE PRONUNCIATION OF THE KOREAN CONSONATS (소구치 발거를 통한 교정치료가 한국어 자음의 발음에 미치는 영향)

  • Lee, Jeong-Hee;Yoon, Young-Jooh;Kim, Kwang-Won
    • The korean journal of orthodontics
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    • v.27 no.1
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    • pp.91-103
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    • 1997
  • This paper aimed to study what the influences of orthodontic treatment of pronunciation are. We compared the duration and the acoustic wave patterns of Korean consonants pronounced by a control group with those of a patient who had his four premolars extracted and had been given orthodontic treatment The results were as follows : 1. Compared to the control group, the treatment group had a longer duration time of consonant pronunciation for all consonants but "ㅅ(s)" and "ㅌ($(t^h)$" in CV(consonant-vowel) pairs. Especially in the case of "ㅈ(dz)", "ㅆ$({\varphi}^h)$" for CV-pairs, and "ㄷ(d)" in VCV(vowel-consonant-vowel) clusters, the duration of consonant sound showed a sharp contrast between the control group and the treatment group. 2. There were clear differences in the acoustic wave patterns of "ㅉ(ts)", "ㅆ$({\varphi}^h)$" and "ㅊ$(c^h)$", all of which were in VCV-clusters. The acoustic wave pattern of "ㅉ(ts)", when pronounced by the treatment group, was stronger than the control group's. This phenomenon was most remarkable in the transitive section where the "ㅉ(ts)" sound flowed into the following vowel. When a preceding vowel shifted to the consonant "ㅆ$({\varphi}^h)$", the attack property of the appeared clearly in the acoustic waves of the treament group, while in the control group the starting point of consonart was indistinctive. Consonant duration for the treatment group was longer, and the appearance of a zero crossing point in the acoustic wave was more frequent. In the case of "ㅊ$(c^h)$", the treatment group produced a strong acoustic wave, and the property of aspiration was obvious in it. 3. When the treatment group pronounced "ㄷ(d)" and "ㅈ(dz)" in CV-pairs, the acoustic-wave was similar to that of aspirated "ㅌ$(t^h)$" and "ㅊ$(c^h)$". 4. The aspirated "ㅌ$(t^h)$" and "ㅊ$(c^h)$" pronounced by the treatment group showed the stronger airstream and acoustic wave form.

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Effect of Different Dietary n-6 to n-3 Fatty Acid Ratios on the Performance and Fatty Acid Composition in Muscles of Broiler Chickens

  • Mandal, G.P.;Ghosh, T.K.;Patra, A.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.11
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    • pp.1608-1614
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    • 2014
  • The objective of this study was to investigate the different dietary ratios of n-6 to n-3 (n-6/n-3) fatty acid (FA) on performance and n-6/n-3 FA in muscles of broiler chickens. A total of 300 one-day-old Cobb chicks were randomly assigned to 3 treatments of 10 replicates in each (10 birds/replicate). Birds were fed on a corn-soybean meal-based diet containing 1% oil during starter (day 1 to 21) and 2% oil during finisher (day 22 to 39) phases, respectively. Treatments of high, medium and low dietary n-6/n-3 FA were formulated by replacing rice bran oil with linseed oil to achieve n-6/n-3 FA close to >20:1, 10:1 and 5:1, respectively. Average daily gain, average daily feed intake, and feed conversion ratio were similar (p>0.05) among the treatments. Serum glucose, cholesterol and triglycerides concentrations were not affected (p>0.05) by dietary treatments. In breast, concentration of C18:3n-3 was significantly greater (p = 0.001) for medium and low vs high n-6/n-3 FA, while concentrations of C20:5n-3, C22:6n-3, total n-3 FA, and n-6/n-3 FA were significantly higher for low vs medium, and medium vs high dietary n-6/n-3 FA. In contrast, concentrations of C18:2 and mono-unsaturated FA (MUFA) were lower for low vs high dietary n-6/n-3 FA. In thigh muscles, concentrations of C20:5n-3 were higher (p<0.05) for medium and low vs high dietary n-6/n-3 FA, and concentrations of C18:3n-3, C22:6, and n-3 FA were greater (p<0.05) for medium vs high, low vs medium dietary n-6/n-3 FA. However, concentrations of C18:1, MUFA, n-6/n-3 were lower (p<0.05) for low and medium vs high dietary n-6/n-3 FA. In conclusion, lowering the dietary n-6/n-3 FA did not affect the performance of chickens, but enhanced beneficial long-chain n-3 FA and decreased n-6/n-3 FA in chicken breast and thigh, which could be advantageous for obtaining healthy chicken products.

A study on the current status of oriental medical care services in health centers and implications for its expansion (보건소장의 한방진료에 대한 태도와 관련 요인 분석)

  • 류규수;김문수
    • Korean Journal of Health Education and Promotion
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    • v.18 no.2
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    • pp.157-168
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    • 2001
  • Currently the oriental medical care services in the health centers is getting popularity because of their unique aspects which western medicine can not cover. This study was conducted to speculate the current status of oriental medical care services in health centers and possibility of how to effectively provide the oriental medical care services(or traditional medical care services) in health centers. For the study, the survey questionnaires were distributed to all 269 health centers and 138(51.3%) of them were collected. Eight of the collected were inadequate for the analysis and 130 of 269 questionnaires were finally chosen for the study. The SPSS/PC WIN 8.0 was used for the statistical analysis. The results are as follows. First, 91 out of 130 sample health centers(70%) are providing oriental medical care services. The results show that the willingness of the directors and the public awareness in community are the most important factors to provide oriental medical care services in health centers. In contrast, the lack of cooperative efforts between western and oriental medical doctors and the lack of government supports are considered as factors that intervene the oriental medical care services in health centers. About 80% of the sample health centers respond that the government supports is needed for oriental medical care services in health centers. Second, it was asked to the directors of 39 health centers which do not provide oriental medical care services regarding their future plan to include the services. About 70% of health centers respond that no plan is available now. They acknowledge that the demand on the services is the most important factor to consider the oriental services as their future medical services. Third, 69.2% of the oriental medical doctors in health centers are public health doctor. 95.6% of the sample health centers have space for the oriental medical care services in their facilities and some health centers provide the services through the private clinics nearby facilities. Finally, the surveyors consider both budgetary constraints and difficulty in recruiting doctors as barriers for the effective oriental medical care services in health centers. Finally, t-test and LSD were employed to find out the difference among several groups. The analysis shows statistically significant difference among groups about their recognition on health care policy, health care system, and effectiveness of oriental medical care services. To be conclude, the study shows the necessity of oriental medical care services in health centers. To do so, the government supports, cooperative efforts between oriental and western medical doctors, and providing job security for doctors should proceed to provide effective oriental medical care services in health centers.

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Metallurgical Investigation and Functional Consideration of the Iron Swords from Bongseon-ri Site in Seocheon (서천 봉선리유적 출토 철제대도의 금속학적 조사 및 기능성 고찰)

  • Cho, Hyun Kyung;Jung, Young Sang;Cho, Nam Chul;Lee, Hun
    • Journal of Conservation Science
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    • v.30 no.2
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    • pp.111-122
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    • 2014
  • In Bongseon-ri site, the central type and the local type of the Baekje tombs co-exist together. Many swords with ring pommel which to regional leaders in Seocheon the Beekje government granted are excavated from these tombs. These represent that the regional leaders were controlled by the Baekje government gradually. Four swords with ring pommel and one simple sword are investigated metallurgically and we seek what swords have a function of weapon or what sword produce for grave goods. The simple sword is made by solid carburizing technology and quenching of heat treatment so it's possibly used as a weapon. In contrast, four swords with ring pommel has little chance of weapon because the blade of swords consists of microstructure that have low hardness and the back of swords don't have microstructure can absorb the shock. The most identical characteristic of the simple sword and swords with ring pommel is that they are possible to classify clearly into practical/non-practical tools. Additionally, according to non-metallic inclusion analysis result of these swords, w$\ddot{u}$stite and glass phase are found together. Thus, it is able to say that reduction method in low temperature is applied during smelting process.

A Study on the Health Professional's Perception of Postpartal care (건강전문가의 산후관리 인식에 대한 연구)

  • Jang, Moon-Hee;Yoo, Eun-Kwang
    • Women's Health Nursing
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    • v.5 no.3
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    • pp.313-326
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    • 1999
  • This study sought to find out the level of perception of postpartal care and the meaning and opinion of traditional postpartal care (Sanhujori) from health professional. The subjects were 188 health professionals who work at University hospital, clinics, Oriented clinics, and midwifery clinics in Seoul and Chung-Buk, Korea. Data were collected from 8th April, 1999 to 6th May, 1999. The data were analyzed through the SPSS program by use of frequency, percentage, t-test, ANOVA and Scheffe test as a post hoc contrast, $x^2$-test, and stepwise multiple regression. The results of the study were as follows: mean age of the subject was 33.0 years and female was 58.0%. Occupation of the subject was nurse 28.7%, doctor 22.3%, midwife 21.3 Korean Oriental doctor 27.0%. Mean period of career was 7.6 years and the subject who experienced Sanhujori was 54.3%. The subject who did not know 6 principles of Sanhujori was 73.9%. In the opinion on traditional Sanhujori method 68.1% of respondents expressed that Sanhujori is scientific postpartal care which fits Korean people's physical constitution and culture. On the opinion of effective postpartal care in 97.9% of respondents expressed that it is to in hospital postpartal care and traditional Sanhujori perform it according to Korean culture constitution. On the opinion of Sanhujori, 96.6% of respondents expressed that it is necessary to understand Sanhujori with consideration which was adapted to Oriental culture and to verify it through continual study. On the opinion of the effect of the level of performance of Sanhujori upon women's health life, 43.2% of respondents expressed that the level of performance of Sanhujori has great effect on women's general health, including postpartal recovery, Sanhujori prevention, and so on. On the opinion of Sanhujori of women who undergo Caesarean operation, 57.7% of respondents expressed that women who undergo Caesarean operation perform Sanhujori with more attention. On the opinion of Sanhujori center (sanhujorwon), 56.3% of respondents expressed that the center is necessary for women's health and health professional are required to manage the center scientifically. On considering the level of importance of post care according to occupation, midwife showed highest level of importance of traditional Sanhujori doctor the lowest level. Midwife showed the hi level of importance of postpartal care and K Oriental doctor showed the lowest level of importance of women's postpartal care. On considering the relationship between the level of importance of postpartal care and general characteristics, sex, career, clinical department and whether they know 6 principles of Sanhujori or not were statistically significant at the level of 5%. In the stepwise multiple regression analysis, the main influencing variables on the level of importance of postpartal care were occupation, sex, and clinical department. In conclusion, this finding confirmed that professionals were considering the traditional Sa importantly for women's health. Above all things necessary for health professional to integrate concept of traditional Sanhujori into practical nu intervention program, to apply it to profes practices in order to reestablish effective integrative postpartal caring system, and to Sanhujori scientific through performing continual research.

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Customers' perception of the attributes of different formats of menu labeling: a comparison between Korea and the U.S.

  • Bosselman, Robert;Choi, Hyung-Min;Lee, Keum Sil;Kim, Eojina;Cha, Jaebin;Jeong, Jin-Yi;Jo, Mina;Ham, Sunny
    • Nutrition Research and Practice
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    • v.14 no.3
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    • pp.286-297
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    • 2020
  • BACKGROUND/OBJECTIVES: This study compared the perception of customers from Korea and the U.S. on the attributes of different formats of menu labeling The specific objectives were 1) to compare the customers' perceived usefulness, ease-of-understanding, clarity, and attractiveness of different formats of menu labeling between Korea and the U.S.; and 2) to compare the customers' use intention to different formats of menu labeling between Korea and the U.S. SUBJECTS/METHODS: A survey was conducted in Korea and the U.S. The participants were allocated randomly to view 1 of the 7 restaurant menus that varied according to the following types of menu labeling formats: (type 1) kcal format, (type 2) traffic-light format, (type 3) percent daily intake (%DI) format, (type 4) kcal + traffic-light format, (type 5) kcal + %DI format, (type 6) traffic-light + %DI format, and (type 7) kcal + traffic-light + %DI format. A total of 279 Koreans and 347 Americans were entered in the analysis. An independent t-test and 1-way analysis of variance were performed. RESULTS: Koreans rated type 4 format (kcal + traffic light) the highest for usefulness and attractiveness. In contrast, Americans rated type 7 (kcal + traffic light + %DI) the highest for usefulness, ease-of-understanding, attractiveness, and clarity. Significant differences were found in the customers' perceived attributes to menu labeling between Korea and the U.S. Americans perceived higher for all the 4 attributes of menu labeling than Koreans. CONCLUSIONS: The study is unique in identifying the differences in the attributes of different formats of menu labeling between Korea and the U.S. Americans rated the most complicated type of menu labeling as the highest perception for the attributes, and showed a higher use intention of menu labeling than Koreans. This study contributes to academia and industry for practicing menu labeling in different countries using different formats.

The study of Literature Review on the pathological mechanism and Therapeutic methods of sudden coma -Focused on Different opinion of successive dynastic medical group in HwangJeNaeKyung and SangHanRon- (궐증(厥證)의 병인병기(病因病機) 및 치방(治方)에 관한 문헌적(文獻的) 고찰(考察) -내경(內經)과 상한론(傷寒論)에 대(對)한 역대의가(歷代醫家)의 견해(見解) 차이(差異)를 중심(中心)으로-)

  • Ryu Hyung-Cheon;Kwack Jeong-Jin;Choi Chang-Won;Lee Gang-Nyoung;Lee Young-Soo;Kim Hee-Chul
    • Herbal Formula Science
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    • v.11 no.1
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    • pp.57-90
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    • 2003
  • The result of Bibliographic studies on the pathological mechanism of the sudden coma, we got the conclusion like this. 1. The sudden coma is an acute syndrome that refers to be a sudden fainting, an unconsciousness, an aphasia or a cold clammy limb, and immediately awakes or dies, and awakes in a short time, and if we awake, it doesn't leave over and above a sequela. 2. The clinical presentation of the sudden coma can be summarized as follows : The 1st is a disease raising the sudden death due to unconsciousness accompanied by wry mouth & sudden syncope with coma. The 2nd is simply the state of cold limbs. The 3rd is the meaning of the physique and symptomes of the six meridians. The last is the ancient method of expression in contrast of the beriberi. 3. The pathological mechanism of the sudden coma consists of the toxoid from outside, Qi and Xie, fatigue, damp phegm, the damage from seven emotions and the damage from five mental elements, especially the mental disorder due to the angry energy, causes the problems when the fleming-up of liver fire and the depressed of liver qi raise the physiological disorder. 4. Therapeutic methods of sudden coma are soothing the liver and remove stasis, soothing depression and circulating of the qi, calming the liver and suppressing yang. When that is early stage, at first, we must checking upward adverse flow of the qi after promoting the circulation of qi and awakening, and then, we must regulate excessive deficiency of yin yang by therapy that is based on differentiated in symptoms according to heat & cold, deficiency & excess, and use invigorating herb medicine for supporting vigour.

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