• Journal of the Korea Academia-Industrial cooperation Society
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• 제14권7호
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• pp.3191-3196
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• 2013

Ultrasonic transducer is the sensor which is measuring distance. Piezo ceramic of ultrasonic sensor and adhesive technique of matching layer are the most core techniques. With the study of relation on matching layer which takes off the ultrasonic wave into the air, this paper aims to find the second useful frequency as the results which can be changed are extracted in case piezo ceramic and matching layer are bonded. And the experiment is done with piezo ceramic as real piezoelectric element and matching layer of chemical wood. OD of piezo ceramic has designed by ${\Phi}50{\times}3T$ and OD of matching layer is designed by ${\Phi}62{\times}12t$ with ${\lambda}=1/4$. Acoustic impedance is generated at the most optimum resonant frequency of 53 Khz. As experimental result, more available frequency can be generated by using the adhesive close to solid than the flexible one.

• YAKHAK HOEJI
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• 제50권5호
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• pp.301-307
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• 2006

A simple and sensitive high-performance liquid chromatographic method for quantitation of hydrochlorothiazide in human plasma was developed and bioavailability parameters of hydrochlorothiazide were assessed in Korean healthy male volunteers. Caffeine was used as an internal standard. Hydrochlorothiazide and internal standard in plasma sample were extracted using tert-butylmethylether (TBME). A centrifuged upper layer was then evaporated and reconstituted with mobile phase of acetonitrile-25 mM phosphate buffer (20/80, pH 2.5). The reconstituted samples were injected into a Luna C18 column $(250{\times}4.6\;mm,\;5{\mu}m)$ at a flow-rate of 1.0 ml/min. The wavelength was set at 230 nm and no endogenous substances were found to interfere, A linear relationship for hydrochlorothiazide was found in the range of $10{\sim}300\;ng/ml$. The lower limit of quantitation (LLOQ) was 10 ng/ml with acceptable precision and accuracy. Assayed in plasma, the intra- and inter-day validation for all coefficients of variation (R.S.D.%) were found less than 15%. Main pharmacokinetic parameters of 50mg of hydrochlorothiazide were revealed as follows: $AUC_t\;1761{\pm}509.0\;ng{\cdot} hr\;ml,\;C_{max}\;296.5{\pm}95.5\;ng/ml,\;T_{max}\;1.94{\pm}0.85hr,\;K_{el}\;0.12{\pm}0.04\;hr^{-1}\;and T_{12}\;6.81{\pm}2.92\;hr.\;C_{max}\;and\;T_{max}$ were in accordance with the values $(270{\sim}350\;ng/ml\;and\;1.9{\sim}2.7\;hr)$ of Caucasian.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• 제20권2호
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• pp.141-146
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• 2009

A triangular microstrip antenna with T-shaped slits is proposed for tunable dual-band applications. The proposed antenna is designed using chip capacitors as a prototype. From this result the capacitor can be replaced to a varactor diode to control capacitance value. Since the input impedance of the antenna can be varied with the value of the chip capacitors on the T-shaped slits, the resonant frequency may be changed. The return losses are better than 10 dB at the lower band of $0.78{\sim}1.21$ GHz and 20 dB at the upper band of $1.97{\sim}2.17$ GHz, respectively. This antenna has the bandwidth of about 10 MHz and 50 MHz at each band. The peak gains of the antenna yield 0 dBi at the lower band and 3 dBi at the upper band, respectively. Details of the antenna design are described, and its performances are presented and analyzed.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• 제50권4호
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• pp.467-475
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• 2014

This study was performed to estimate optimum fishing mortality (F) and the age at first capture ($t_c$) for small yellow croaker in Korean waters. We first estimated optimum F and $t_c$ using traditional yield-per-recruit (YPR) analysis, and the results were 0.8/year and 2.5 years old, respectively. However, the individual fish price per unit weight of small yellow croaker in Korea increases dramatically by size. Thus, we developed an alternative method, which is called as production value-per-recruit (PPR) analysis. We developed two types of the PPR analysis, that is, the discrete function and the continuous function method. We estimated optimum F and $t_c$ using the two types of the PPR analysis and compared the results. The optimum F and $t_c$ from the discrete function method, were 0.3/year and 5.0 years old, respectively, while those from the continuous function method were 0.5/year and 3.5 years old, respectively. These PPR estimates were much more conservative for the stock management than the traditional YPR analysis, which can prevent the fish stock from the economic overfishing. As a result, the PPR analysis could be more proper approach for stock assessment in the case that the individual fish price per unit weight increases dramatically by size like small yellow croaker in Korea.

• Korean Journal of Microbiology
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• 제46권1호
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• pp.93-95
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• 2010

White rot fungi which have lignin degrading enzymes show high degrading activity to diverse recalcitrant compounds such as polycyclic aromatic compounds, dyes, explosives and endocrine disrupting chemicals. We have examined decolorizing activity of dyes by Phlebia tremellosa and two transformants which had genetically transformed using laccase or manganese peroxidase (MnP) gene. In case of methyl green, wild type strain showed 50% decolorization while laccase transformant (TF2-1) and MnP transformant (T5) showed more than 90% decolorization on day 3. Remazol brilliant blue R(RBBR) was decolorized up to 85% by two transformants while the wild type showed 67% decolorization on day 3. Transformants TF2-1 and T5 both showed increased laccase and MnP activity respectively during the whole growing phase.

• Korean Journal of Clinical Pharmacy
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• 제21권2호
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• pp.131-137
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• 2011

The purpose of this study was to evaluate the clinical efficacy of a standardized special ethanol extract from Gynostemma pentaphyllum as a management for anxiety and stress of normal population. This is a two-arm, parallelgroup, randomized, double blind clinical trial comparing Gynostemma pentaphyllum extract 200 mg bid (GP-EX, n=48) or placebo bid (n=54). The main outcome measures were the decrease in anxiety sensitivity index (ASI), the State version (S-STAI) of the Stait-Trait Anxiety Inventory (STAI) and the Trait version (T-STAT) of the STAI from baseline over a 6 weeks treatment period. In more anxious group (S-STAI50 or ASI19), the anxiety in group with GP-EX was decreased significantly than one in normal population with placebo [S-STAI50: T-STAI = from $57.7{\pm}6.5$ ($mean{\pm}S.D.$) to $46.8{\pm}11.2$ in normal population with GP-EX, p=0.002 vs. from $54.1{\pm}9.9$ to $49.0{\pm}9.6$ in normal population with placebo, p>0.05; ASI19: T-STAI = from $47.2{\pm}12.0$ to $42.4{\pm}11.1$ in normal population with GP-EX, p=0.022 vs. from $48.7{\pm}11.5$ to $46.0{\pm}10.4$ in normal population with placebo, p>0.05]. The most frequently reported adverse reactions considered possibly related to treatment were mild gastrointestinal events. GP-EX is more effective than placebo and is well tolerated as a therapy for anxiety and stress of normal population.

• Transactions of the Korean Society of Mechanical Engineers A
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• 제38권9호
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• pp.999-1004
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• 2014

In the present paper, the effects of initial crack location on spatial randomness of fatigue crack growth resistance (FCGR) in friction stir welded (FSWed) AA7075-T651 plates were studied. The objective of this study is to characterize the statistical properties of FCGR for three different types of initial crack location (ICL) specimens. In this work, the FCGR coefficients were treated as a spatial random process. It was found that the FCGR coefficients for all initial crack location specimens closely followed a two parameter Weibull distribution. The shape parameter of the Weibull distribution for BM-ICL specimens showed the largest value of 7.50, and that for the WM-ICL specimens showed the smallest value of 2.61. In addition, the autocorrelation functions for all the ICL specimens followed the exponential function.

• The Journal of Korean Society of Virology
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• 제28권4호
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• pp.359-368
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• 1998

Cytomegalovirus is the most common cause of life-threatening viral infection in HIV-infected patients. This study was done prospectively to investigate the incidence of CMV infection according to the decrease of CD4+ T cell count (CD4+) in Korean AIDS patients. Thirty-nine HIV-infected patients diagnosed before 1994 were followed for regular immunological monitoring. We have used urine shell vial method for the CMV detection from 1994 and have also checked clinical findings. Positive urine culture rate definitely depended on the CD4+ as follows; 45%, 22%, 17%, 11% and 0%, CD4+ <50, 50-100, 100-200, 200-500 and >500, respectively. Except culture positive 2 patients with CD4+ of $200{\sim}300/{\mu}l$, all eight culture positive patients with CD4+ less than $200/{\mu}l$ showed CMV related diseases on or before urine culture. But, we could not get a positive culture for a late AIDS patient with vision loss. With ganciclovir therapy, all culture results were at least negative just after or on late of first 14 days-ganciclovir infusion-course. These data suggest that the incidence of CMV disease in Korean AIDS patients is very high, and early diagnosis and treatment for CMV diseases is required for the prevention of life threatening results.

• Journal of Korea Water Resources Association
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• 제37권2호
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• pp.163-172
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• 2004

In this paper, the sub-soil storage system for utilizing urban instream flow of rainfall runoff was developed and examined through experiments. The artificial rainfall facility and sub-soil storage were installed in the experimental area. The effect of the water qualify improvement and the storage effect were analyzed through the several experiments. Through the experiments of rainfall intensity variation, which are the rainfall intensity of 20mm/hr, 30mm/hr, 40mm/hr, 50mm/hr was indicated SS concentration can be reduction until 68％. Also, the ration of the storage volume is varied from 42.8％∼79.9％ based on the rainfall intensity. The reduction rate of the BOD, CO $D_{Mn}$, SS, T-N, T-P was 30％, 42％, 68％, 39％, 26％. As the result, water quality of runoff and efficient of runoff reduction by the system are much improved. The rainfall runoff with the installation of sub-soil storage could be used for instream flow.

• Environmental Analysis Health and Toxicology
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• 제22권1호
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• pp.83-90
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• 2007

This study was investigated the effort of growth and gonadal development in olive flounder, Paralichthys olivaceus exposed to PCBs Effluent Allowance Concentration, 3.0 ppb in Korea. Total length, body weight and weight gam of fish were no significant differences between two treatments (control: T.L.-110.0 mm, T.W.-9.61 g: treatment: T.L.-112.8 mm, T.W.-9.68 g), however, weight gain of fish unexposed to PCBs wat observed to increase gradually from 100 days after hatching (30 days after treatment). In the indifferentiated gonad to the juvenile stage, the differentiation of the ovary occured at 60 days after hatching (20 days after treatment) and that of the testis occured at 70 days after hatching (30 days after treatment) in two groups. In the ovary, the oogonia and ovarian lamellar appeared 130 days after hatching (50 days after treatment). The spermatogonia and resticular lobule of the testis were observed at 130 days after hatching (50 days after treatment). Testicular cyst appeared 140 days after hatching (60 days After treatment). There was no difference on the development of ovary and testis. There was no obvious difference of sex ratios. Therefore, These results considerate that PCBs have any effect for growth and gonadal development, but a little act for early growth in olive flounder.