• 대한의용생체공학회:의공학회지
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• 제33권1호
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• pp.47-52
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• 2012

The purpose of this study is to investigate whether medication and deep brain stimulation (DBS) have differential effects on the speed and amplitude of bradykinesia in patients with Parkinson's disease (PD). Five PD patients with implanted DBS electrodes (age: $60.6{\pm}7.4yrs$, H&Y stage: $3.1{\pm}0.2$) participated in this study. FT (finger tapping) movement was measured using a gyrosensor system in four treatment conditions: Med (Medication)-off/DBS-off, Med-off/DBS-on, Med-on/DBS-off and Med-on/DBS-on. Quantitative measures representing average speed and amplitude of FT movement included root-mean-squared (RMS) angular velocity and RMS angle. One-way repeated measures ANOVA showed that RMS angular velocity of Med-on/DBS-on was significantly greater than those of Med-off/DBS-off and Med-off/DBS-on (p < 0.01) whereas RMS angle was not different among conditions (p = 0.06). Two way repeated measures ANOVA showed that only medication improved RMS angular velocity (p < 0.01), whereas both medication and DBS had no significant effect on RMS angle (p > 0.02). Effect size of RMS angular velocity was greater than that of RMS angle in both medication and DBS. This suggests that medication and DBS have differential effects on FT bradykinesia and velocity and amplitude impairments may be associated with different functional aspects in PD.

• 한국자동차공학회논문집
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• 제19권1호
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• pp.82-88
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• 2011

Lean combustion and exhaust emission characteristics in a ethanol fueled spark-ignited engine according to ethanol-gasoline fuel blending ratio were investigated. The test engine was $1591cm^3$ and 10.5 of compression ratio SI engine with 4 cylinders. In addition, lambda sensor system was connected with universal ECU to control the lambda value which is varied from 1.0 to 1.5. The engine performance and lean combustion characteristics such as brake torque, cylinder pressure and rate of heat release were investigated according to ethanol-gasoline fuel blending ratio. Furthermore, the exhaust emissions such as carbon monoxide (CO), unburned hydrocarbon (HC), nitrogen oxides ($NO_x$) and carbon dioxide ($CO_2$) were measured by emission analyzers. The results showed that the brake torque, cylinder pressure and the stability of engine operation were increased as ethanol blending ratio is increased. Brake specific fuel consumption (BSFC) was increased in higher ethanol blending ratio while brake specific energy consumption (BSEC) was decreased in higher ethanol blending ratio. The exhaust emissions were decreased as ethanol blending ratio is increased under overall experimental conditions, however, some specific exhaust emission characteristics were mainly influenced by lambda value and ethanol-gasoline fuel blending ratio.

• The Journal of Advanced Prosthodontics
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• 제8권3호
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• pp.201-206
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• 2016

PURPOSE. The aim of this study was to compare the radiopacity of 6 modern resin cements with that of human enamel and dentine using the Digora digital radiography system, to verify whether they meet the requirements of ANSI/ADA specification no. 27/1993 and the ISO 4049/2000 standard and assess whether their radiopacity is influenced by the thickness of the cement employed. MATERIALS AND METHODS. Three 3-thickness samples (0.5, 1 and 1.5 mm) were fabricated for each material. The individual cement samples were radiographed on the CCD sensor next to the aluminium wedge and the tooth samples. Five radiographs were made of each sample and therefore five readings of radiographic density were taken for each thickness of the materials. The radiopacity was measured in pixels using Digora 2.6 software. The calibration curve obtained from the mean values of each step of the wedge made it possible to obtain the equivalent in mm of aluminium for each mm of the luting material. RESULTS. With the exception of Variolink Veneer Medium Value 0, all the cements studied were more radiopaque than enamel and dentin (P<.05) and complied with the ISO and ANSI/ADA requirements (P<.001). The radiopacity of all the cements examined depended on their thickness: the thicker the material, the greater its radiopacity. CONCLUSION. All materials except Variolink Veneer Medium Value 0 yielded radiopacity values that complied with the recommendations of the ISO and ANSI/ADA. Variolink Veneer Medium Value 0 showed less radiopacity than enamel and dentin.

• 실천공학교육논문지
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• 제11권2호
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• pp.167-174
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• 2019

비전공 학부생을 대상으로 Java 프로그래밍 교육을 실시하는 데 있어, 피지컬 컴퓨팅 교육 방법을 적용한 사례는 전무하다고 할 수 있다. 피지컬 컴퓨팅 교육의 장점은 디지털 및 아날로그 센서의 입력 값에 따른SW 처리 출력 결과를 직접 확인할 수 있어, 프로그래밍 오류를 빠르게 수정하고 학습자의 학습 관심과 만족도를 향상시킬 수 있다. 본 논문에서는 마이크로비트를 사용하여, 기초적인 Java 프로그래밍 교육에 피지컬 컴퓨팅 교육을 접목하였다. 그리고, 컴퓨팅적 사고과정에 따라, 마이크로비트를 사용하여 Java 프로그램을 창작해보는 교육 방법을 제안하였다. 마이크로비트를 제어하는 블록 프로그래밍을 통해, 알고리즘을 설계하고, 이에 따라, Java 프로그램으로 변환하는 교육 방법을 적용하였다. 그리고, 본 교육방법을 적용한 강좌에서 학생들의 평가 결과를 분석하여, 마이크로비트를 활용한 교육방법의 유효성을 분석하였다.

• 한국추진공학회지
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• 제17권1호
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• pp.89-96
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• 2013

산화제 과잉 예연소기의 연소안정성을 알아보기 위하여 예연소기의 각 부위에서 압력을 측정하였다. 압력측정은 정압센서와 동압센서를 모두 이용하여 이루어졌다. 이 때 사용된 정압센서와 동압센서의 해상도는 각각 최고 1000 Hz와 25,600 Hz이다. 예연소기의 정격압은 200 bar이나 위험을 줄이기 위하여 초기에는 80 bar로 낮추어 시험을 하였고 안정성이 확인된 이후 200 bar 시험을 실시하였다. 또한 모든 시험에서 점화충격을 줄이기 위하여 저압점화 후 연소압을 정격압력까지 올리는 2단 점화를 사용하였다. 시험은 최대 약 10초가량 실시되었으며 메인모드 진입 이후에는 연소압에 큰 변화 보이지 않았다. 연소압의 측정결과는 FFT를 통해 좀 더 심도 있게 분석되었으며 그 결과 예연소기의 연소안정성을 해할 만한 주파수의 커플링은 발견되지 않았다. 따라서 현재 개발되고 있는 예연소기는 향후 다단 연소사이클 엔진 연구에 활용할 수 있을 것으로 기대한다.

• 한국소음진동공학회논문집
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• 제14권6호
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• pp.512-519
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• 2004

This paper described the free vibration characteristics of Optimized H Type (OHT) spacer grids (SG) supporting the PWR fuel rod. The vibration test and the finite element (FE) analysis are performed under the free boundary condition and the clamped at two points (or three points) in the bottom which is the same one as the experimental condition for the dummy rod continuously supported by spacer grids. A modal test is conducted by the impulse excitation method using an impulse hammer and an accelerometer, and the TDAS module of the I-DEAS software is used to acquire and analyze the sensor signals. The softwares related to the FE analysis are the I-DEAS for the geometrical shape modeling and meshing, and the ABAQUS for solving. The fundamental frequency of the OHT SG by experiment under a clamped condition at two points is 175.18 Hz, and shows a bending mode. We think there is no resonance between the fuel rod and the SG because the SG's frequency is higher than that of the fuel rod existing in the range from 30 to 120 Hz. The fundamental frequency of the SG under the free boundary condition is 349.2 Hz showing a bending mode, and the results between the test and the analysis have a good agreement with maximum 7 ％ in error It is also found that the FE analysis model of the OHT SGs to analyze an impact, a buckling and vibration et al. has been generated with reliability.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권4호
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• pp.235-244
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• 2018

Background: Patients with intellectual disability (ID) often require general anesthesia during oral procedures. Anesthetic depth monitoring in these patients can be difficult due to their already altered mental state prior to anesthesia. In this study, the utility of electroencephalographic indexes to reflect anesthetic depth was evaluated in pediatric patients with ID. Methods: Seventeen patients (mean age, $9.6{\pm}2.9years$) scheduled for dental procedures were enrolled in this study. After anesthesia induction with propofol or sevoflurane, a bilateral sensor was placed on the patient's forehead and the bispectral index (BIS) was recorded. Anesthesia was maintained with sevoflurane, which was adjusted according to the clinical signs by an anesthesiologist blinded to the BIS value. The index performance was accessed by correlation (with the end-tidal sevoflurane [EtSevo] concentration) and prediction probability (with a clinical scale of anesthesia). The asymmetry of the electroencephalogram between the left and right sides was also analyzed. Results: The BIS had good correlation and prediction probabilities (above 0.5) in the majority of patients; however, BIS was not correlated with EtSevo or the clinical scale of anesthesia in patients with Lennox-Gastaut, West syndrome, cerebral palsy, and epilepsy. BIS showed better correlations than SEF95 and TP. No significant differences were observed between the left- and right-side indexes. Conclusion: BIS may be able to reflect sevoflurane anesthetic depth in patients with some types of ID; however, more research is required to better define the neurological conditions and/or degrees of disability that may allow anesthesiologists to use the BIS.

• The Journal of Korean Physical Therapy
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• 제24권2호
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• pp.113-117
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• 2012

Purpose: The purpose of this study was to analyze the weight bearing of the cane and foot for the different walking aids during walking. Methods: A total of 12 subjects (6 males, 6 female) with stroke were enrolled in the study. Foot sensor and an instrumented cane were integrated to analyze the vertical peak force on the foot and cane. Results: The vertical peak force applied on the quad cane gait resulted in a significantly higher rate, which was $10.60{\pm}6.48%$ of the body weight, when compared to that of mono cane gait which was $7.91{\pm}4.11%$. The results indicated significantly lower vertical peak force on the affected foot, without the help of a walking aid, as compared to that of walking with a cane (respectively, p<0.05). However, results showed that the differences in vertical peak force on the affected foot, between mono cane and quad cane, were not significant. Conclusion: In conclusion, the vertical peak forces were significantly greater, during a comparison between walking with a quad cane and walking with a mono cane. On the contrary, no significant difference in the vertical peak force on the affected foot between walking with quad cane and walking with a mono cane. Muscle activation pattern and walking pattern should be measured in future studies, to study the differences between walking with various walking aids in the lower and higher functioning hemiparetic subjects, as its use may mask underlying gait impairment.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.549-549
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• 2012

Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.

• 대한치과보철학회지
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• 제45권5호
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• pp.687-695
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• 2007

Statement of problem: The proper contact relation between adjacent teeth in each arch plays an important role in the stability and maintenance of the integrity of the dental arches. Proximal contact has been defined as the area of a tooth that is in close association, connection, or touch with an adjacent tooth in the same arch. Purpose: The aim of this study was to develop a digital device for measuring the proximal tooth contact tightness by pulling a thin stainless steel strip (2mm wide, 0.03mm thick) inserted between proximal tooth contact. Material and method: This device consists of measuring part, sensor part, motor part and body part. The stainless steel strip was connected to a stain gauge. The strain gauge was designed to convert the frictional force into a compressive force. This compressive force was detected as a electrical signal and the electrical signal was digitalized by a A/D converter. The digital signals were displayed by a micro-processor. The pulling speed was 8mm/s. Results: For testing reliability of the device in vivo, two healthy young adults (A, B) participated in this experiment. The tightness of proximal tooth contact between the second premolar and the first molar of mandible (subject A) and maxilla (subject B) was measured fifteen times for three days at rest. We double-checked the accuracy of the device with a Universal Testing Machine. Output signals from the Universal Testing Machine and the measuring device were compared. Regression analysis showed high linearity between these two signals. In vivo test, no significant differences were found between measurements. Conclusion: This device has shown to he capable of producing reliable and reproducible results in measuring proximal tooth contact. Therefore, it was considered that this device was appropriate to apply clinically.