• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.2
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• pp.115-121
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• 2005

Using a general Saccharomyces cerevisiae as a model strain, continuous ethanol fermentation was carried out in a stirred tank bioreactor with a working volume of 1,500 mL. Three different gravity media containing glucose of 120, 200 and 280 g/L, respectively, supplemented with 5 g/L yeast extract and 3 g/L peptone, were fed into the fermentor at different dilution rates. Although complete steady states developed for low gravity medium containing 120 g/L glucose, quasi-steady states and oscillations of the fermented parameters, including residual glucose, ethanol and biomass were observed when high gravity medium containing 200 g/L glucose and very high gravity medium containing 280 g/L glucose were fed at the designated dilution rate of $0.027\;h^{-1}$. The observed quasi-steady states that incorporated these steady states, quasi-steady states and oscillations were proposed as these oscillations were of relatively short periods of time and their averages fluctuated up and down almost symmetrically. The continuous kinetic models that combined both the substrate and product inhibitions were developed and correlated for these observed quasi-steady states.

• Journal of Korean Society for Atmospheric Environment
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• v.12 no.3
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• pp.289-296
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• 1996

Effects of crustal species on the characteristics of ambient particles were studied by applying a gas-particle equilibrium model, SCAPE, to the measurements at Kosan, Cheju Island during the spring and summer, 1994. Two cases were simulated; the measured composition was used without any modification (case 1), and the metal ion concentrations originated from crust were subtracted from the measured particle composition (case 2). Total suspended particles (TSPs) were collected by an automatic high volume tape sampler during spring period and by high volume samplers during summer period. The fine particles, PM 2.5, and gaseous volatile species were collected using a filter pack smapler during summer period. The water soluble ion concentrations were analyzed from all the particle samples. According to the simulation results, the effect of crustal elements on the chemical composition of particles is negligible for both TSP particles and PM 2.5 particles. Acidity of particles measured at Kosan, however, is affected by the change of the concentrations of crustal species, stronger effects for TSP particles than for PM 2.5 particles during summer, and stronger effects during summer than spring for TSP particle. The average pH decrease due to the absence of crustal species was about 0.10 for PM 2.5 particle during summer and 1.51 and 0.85 for TSP particles during summer spring, respectively. Water contents of PM 2.5 particles for both cases are comparable to each other. Estimated water content of TSP particles for case 2 is higher than that for case 1 by about 4 $\sim 6 \mum/m^3$ because salts of metal ions are not hygroscopic.

• The KSFM Journal of Fluid Machinery
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• v.14 no.5
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• pp.12-17
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• 2011

The seawater lift pump system is responsible for maintaining the open canal level to provide the suction flow of circulating water pump at the set point. The objective of this paper is to design a 2-stage mixed flow pump (for seawater lifting) by inverse design method and to evaluate the overall performance and the local flow fields of the pump by using a commercial CFD code. Rotating speed of the impeller is 1,750 rpm with the flow rate of 2,700 $m^3$/h. Finite volume method with structured mesh and realized k-${\varepsilon}$ turbulent model is used to guaranty more accurate prediction of turbulent flow in the pump impeller. The numerical results such as static head, brake horse power and efficiency of the mixed flow pump are compared with the design data. The simulated results are good agreement with the design data less 3% error.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.11a
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• pp.277-278
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• 2005

Admittance Spectroscopic analysis was applied to study the effect of LiF buffer layer and to model the equivalent circuit for poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV)-based polymer light emitting diodes (PLEDs) with the LiF cathode buffer layer. The single layer device with ITO/MEH-PPV/Al structure can be modeled as a simple parallel combination of resistor and capacitor. Insertion of a LiF layer at the Al/MEH-PPV interface shifts the highest occupied molecular orbital level and the vacuum level of the MEH-PPV layer as a result the barrier height for electron injection at the Al/MEH-PPV interface is reduced. The admittance spectroscopy measurement of the devices with the LiF cathode buffer layer shows reduction in contact resistance ($R_c$), parallel resistance ($R_p$) and increment in parallel capacitance ($C_p$).

• The Bulletin of The Korean Astronomical Society
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• v.38 no.1
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• pp.59.2-59.2
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• 2013

Wilson and Bappu found a tight correlation between the stellar absolute visual magnitude (MV) and the width of the Ca II K emission line for late-type stars in 1957. Here, we revisit the Wilson-Bappu relationship (hereafter, WBR) to claim that WBR can be an excellent indicator of stellar surface gravity of late-type stars as well as a distance indicator. We have measured the width (W) of the Ca II K emission line in high resolution spectra of 125 late-type stars, which were obtained with Bohyunsan Optical Echelle Spectrograph (BOES) and adopted from the UVES archive. Based on our measurement of the emission line width (W), we have obtained a WBR of $M_V=33.76-18.00{\log}W$. In order to extend the WBR to be a surface gravity indicator, the stellar atmospheric parameters such as effective temperature ($T_{eff}$), surface gravity (logg), metallicity ([Fe/H]), and micro-turbulence (${\xi}_{tur}$) have been derived from the self-consistent detailed analysis using the Kurucz stellar atmospheric model and the abundance analysis code, MOOG. Using these stellar parameters and logW, we found that ${\log}g=-5.85\;{\log}W+9.97\;{\log}T_{eff}-23.48$ for late-type stars.

• Journal of Ocean Engineering and Technology
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• v.25 no.5
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• pp.21-26
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• 2011

Seawater lift pump systems are responsible for maintaining open canal levels to provide the suction flow of circulating water pumps at the set point. The objective of this paper is to design a 2-stage mixed flow pump (for seawater lifting), investigate the new impeller modeling method, and performance improvements of the impeller by using a commercial CFD code. The rotating speed of the impeller is 1,750 rpm with a flow rate of 2,700 m3/h. A finite volume method with a structured mesh and realized k-${\varepsilon}$ turbulent model is used to guarantee a more accurate prediction of turbulent flow in the pump impeller. The performance variables such as the static head, brake horsepower, and efficiency of the mixed flow pump are compared based on changes in the impeller blade shape.

• The Journal of Korean Medicine
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• v.30 no.2
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• pp.63-78
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• 2009

Objective: The purpose of experimental study was to prove the effects of Boyangmakseong-bang (BYMSB) treatment on cBSA-induced in a MN mouse model. Methods: We divided mice into 4 groups. The Normal group had no treatment. We used cBSA and induced MN mouse model to the other 3 groups. The Control group was treated with cBSA (9mg/kg i.p) only. The second group, named 'BY-250', was treated with cBSA (9mg/kg i.p) and BYMSB extract (250mg/kg, p.o). The third group, named 'BY-500', was treated with cBSA (9mg/kg i.p) and BYMSB extract (500mg/kg, p.o). After cBSA and BYMSB extract treatment for 4 weeks, the increase in percentage of body weight, proteinuria, serum albumin, total cholesterol, creatinine and BUN of all groups were measured. The CD3+, CD19+, CD4+, CD8+ cell levels of spleen of all groups were analyzed. IgA, IgG, IgM, IL-$1{\beta}$, TNF-${\alpha}$, IL-6 and IFN-${\gamma}$ levels of all groups were gauged. H&E staining, immunofluorescence staining and electron microscopy of kidney were observed. Results: BYMSB showed significant decrease in the 24hrs proteinuria, serum total cholesterol, serum IgG levels and BUN levels, and showed significant increase in the serum albumin levels compared with the control group. BYMSB showed increase in the increasing percentage of body weight and IFN-${\gamma}$ levels compared with the control. BYMSB showed decrease in the CD3+ T cells, CD4+ Th cells, IL-$1{\beta}$, TNF-${\alpha}$ and IL-6 levels, but did not show significant change compared with the control. BYMSB showed considerable decrease in the thickening of the GBM on H&E staining, deposition of IgG on immunofluorescence staining and deposition of electron-density on electron microscopy of kidney compared with the control. Conclusions: According to the above results, it is suggested that BYMSB decreases the symptoms of MN induced by cBSA in a mouse model. Therefore BYMSB seems to be applicable to MN in clinical practice.

• Natural Product Sciences
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• v.27 no.3
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• pp.201-207
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• 2021

We have previously reported that Acer tegmentosum extract, which is traditionally used in Korea to reduce alcohol-related liver injury, suppresses liver inflammation caused by excessive alcohol consumption and might improve metabolism. The active ingredient, 6-O-galloylsalidroside (GAL), was isolated from A. tegmentosum, and we hypothesized that GAL could provide desirable pharmacological benefits by ameliorating physiological conditions caused by alcohol abuse. Therefore, this study focused on whether GAL could ameliorate alcoholic fat accumulation and repair liver injury in mice. During chronic alcohol consumption plus binge feeding in mice, GAL was administered orally once per day for 11 days. Intrahepatic lipid accumulation was measured in vivo using a noninvasive method, ¹H magnetic resonance imaging, and confirmed by staining with hematoxylin and eosin and Oil Red O. The serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured using a Konelab system, and the triglyceride content was measured in liver homogenates using an enzymatic peroxide assay. The results suggested that GAL alleviated alcohol-induced steatosis,e as indicated by decreased hepatic and serum triglyceride levels in ethanol-fed mice. GAL treatment also correlated with a decrease in the Cd36 mRNA expression, thus potentially inhibiting the development of alcoholic steatosis via the hepatic de novo lipogenesis pathway. Furthermore, treatment with GAL inhibited the expression of cytochrome P450 2E1 and attenuated hepatocellular damage, as reflected by a reduction in ALT and AST levels. These findings suggest that GAL extracted from A. tegmentosum has the potential to serve as a bioactive agent for the treatment of alcoholic fatty liver and liver damage.

• Journal of Environmental Science International
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• v.11 no.5
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• pp.419-436
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• 2002

The current paper reports on the enhancement of O$_3$, CO, NO$_2$, and aerosols during the Asian dust event that occurred over Korea on 1 May 1999. To confirm the origin and net flux of the O$_3$, CO, NO$_2$, and aerosols, the meteorological parameters of the weather conditions were investigated using Mesoscale Meteorological Model 5(MM5) and the TOMS total ozone and aerosol index, the back trajectory was identified using the Hybrid Single-Particle Lagrangian Integrated Trajectory Model(HYSPLIT), and the ozone and ozone precursor concentrations were determined using the Urban Ashed Model(UAM). In the presence of sufficiently large concentrations of NO$\sub$x/, the oxidation of CO led to O$_3$ formation with OH, HO$_2$, NO, and NO$_2$ acting as catalysts. The sudden enhancement of O$_3$, CO, NO$_2$ and aerosols was also found to be associated with a deepening cut-off low connected with a surface cyclone and surface anticyclone located to the south of Korea during the Asian dust event. The wave pattern of the upper trough/cut-off low and total ozone level remained stationary when they came into contact with a surface cyclone during the Asian dust event. A typical example of a stratosphere-troposphere exchange(STE) of ozone was demonstrated by tropopause folding due to the jet stream. As such, the secondary maxima of ozone above 80 ppbv that occurred at night in Busan, Korea on 1 May 2001 were considered to result from vertical mixing and advection from a free troposphere-boundary layer exchange in connection with an STE in the upper troposphere. Whereas the sudden enhancement of ozone above 100 ppbv during the day was explained by the catalytic reaction of ozone precursors and transport of ozone from a slow-moving anticyclone area that included a high level of ozone and its precursors coming from China to the south of Korea. The aerosols identified in the free troposphere over Busan, Korea on 1 May 1999 originated from the Taklamakan and Gobi deserts across the Yellow River. In particular, the 1000m profile indicated that the source of the air parcels was from an anticyclone located to the south of Korea. The net flux due to the first invasion of ozone between 0000 LST and 0600 LST on 1 May 1999 agreed with the observed ground-based background concentration of ozone. From 0600 LST to 1200 LST, the net flux of the second invasion of ozone was twice as much as the day before. In this case, a change in the horizontal wind direction may have been responsible for the ozone increase.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.49.2-49.2
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• 2016

The number of discovery of asteroids with peculiar rotational states has recently increased, and hence a novel approach for lightcurve analysis is considered to be critical. In order to investigate objects such as Non-Principal Axis (NPA) rotator, we selected a NPA candidate, (5247) Kryolv as our target considering its Principal Axis Rotation (PAR) code and the visibility in early 2016. The observations of Krylov were made using Korea Microlensing Telescope Network (KMTNet) 1.6 m telescopes installed at the three southern sites with TO (Target of Opportunity) observation mode. We conducted R-band time-series photometry over a total of 51 nights from January to April 2016 with several exposures during each allocated run. The ensemble normalization photometry was employed using the AAVSO Photomtric All-Sky Survey (APASS) catalog for the standardization. We successfully confirmed its NPA spin state based on the deviation from the reduced lightcurve, and thus Krylov is recorded as the first NPA rotator of its kind in the main-belt, with its precession and rotation periods, $P{\varphi}=81.18h$ and $P_{\Psi}=67.17h$, respectively. In this paper, we present the spin direction, the 3D shape model and taxonomy of the newly confirmed NPA asteroid (5247) Krylov.