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Usefulness of $^{201}Tl$ Myocardial Perfusion SPECT in Prediction of Left Ventricular Remodeling following an Acute Myocardial Infarction (급성심근경색 후 발생하는 좌심실 재구도 예측에 대한 $^{201}Tl$ 심근관류 SPECT의 운용성)

  • Yoon, Seok-Nam;Park, C.H.;Hwang, Kyung-Hoon
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.1
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    • pp.30-38
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    • 2000
  • Purpose: We investigated the role of myocardial perfusion SPECT in prediction of ventricular dilatation and the role of revascularization including thrombolytic therapy and PTCA in prevention of ventricular dilatation after an acute myocardial infarction (AMI). Materials and Methods: We performed dipyridamole stress, 4 hour redistribution, and 24 hour reinjection Tl-201 SPECT in 16 patients with AMI two to nine days after attack. Perfusion and wall motion abnormalities were quantified by perfusion index (PI) and wall motion index (WMI). Left ventricular ejection fraction (LVEF), WMI and ventricular volume were measured within 1 week of AMI and after average of 6 months. According to serial changes of left ventricular end-diastolic volume (LVEDV), patients were divided into two groups. We compared WMI, PI and LVEF between the two groups. Relationships among degree of volume, stress-rest PI, WMI, CKMB, Q wave, LVEF and revascularization were analysed using multivariate analysis. Results: Only initial rest perfusion index was significantly different between the two groups (p<0.05). While initial LVEF, stress PI, CKMB, trial of revascularization procedure, presence of Q wave and WMI were not significantly different between the two groups. Eight of 16 patients (50%) showed LV dilatation on follow-up echocardiography. Three of 3 patients (100%) who did not undergo revascualrization procedure documented LV dilatation. And only 5 (38%) of the remaining 13 patients who underwent revascularization revealed LV dilatation. There was no difference in infarct location between the two groups. By multivariate linear regression analysis in patients only undergoing revascularization, rest perfusion index was the only significant factor. Conclusion: Myocardial perfusion SPECT performed prior to revascularization was useful in prediction of LV dilatation after an AMI. Rest perfusion index on myocardial perfusion plays as a significant predictor of left ventricular dilatation after AMI. And revascularization appears to be a valuable procedure in alleviating LV dilatation after AMI with or without viable myocardium in a limited number of patients studied retrospectively.

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Evaluation of Maternal Behavior between Normal Parturition and Expected Cesarean Section in Rats (자연 분만 및 예정된 제왕절개 수술 랫드에 있어서 모성 행동의 차이에 대한 검토)

  • Lee, S.K.;Kang, H.G.;Kim, I.W.;Jeong, J.M.;Hwang, D.Y.;Kim, C.K.;Chae, K.R.;Cho, J.S.
    • Journal of Embryo Transfer
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    • v.22 no.3
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    • pp.161-165
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    • 2007
  • Oxytocin is a neurohypophyseal hormone which has multiple functions in mammals. Mainly, oxytocin regulates milk ejection and has an effect on uterine contraction and is related to maternal behavior. Maternal behavior is believed to be suppressed by stress and facilitated by oxytocin. In the cesarean section, oxytocin may be administrated into uterus to promote uterine involution. The present study aimed to test the effect of oxytocin into uterus on maternal behavior of rats with cesarean section. It was measured the effects on maternal behavior of oxytocin infused into uterus in rats with cesarean section as a stressor. In the first experiment, pup survival rate of between a control group and a group with laparotomy as a stress in natural parturition rats was compared. In the second experiment, survival rate for 2 weeks and maternal pup searching behavior (MPSV) were observed in one cesarean sectioned group without oxytocin and the other cesarean sectioned group with oxytocin. Infanticide was observed in stressed group in the first experiment while a normal maternal behavior was observed in a control one. In the second experiment, MPSV was only observed in a cesarean sectioned group with oxytocin and infanticide was observed in two groups except one rat which is thought to be affected by oxytocin as operated relatively late. This is the first study to show that the administration of oxytocin into uterus in the cesarean section is not involved in the regulation of maternal behavior in rats. In conclusion, this study proves the needs of oxytocin into brain in cesarean section related rats model and further study of maternal behavior list, like MPSV.

Fertility status of Jeju volcanic ash soil and its improvement (제주도전토양(濟州道田土壤)의 비옥도현황(肥沃度現況)과 개량(改良))

  • Ryu, In Soo;Yoo, Sun-Ho;Yoon, Jung Hai
    • Korean Journal of Soil Science and Fertilizer
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    • v.8 no.3
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    • pp.121-133
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    • 1975
  • Soils of the agricultural land derived mostly from volcanic ash in Jeju island may be characterized by relatively high PH, high contents of organic matter and exchangeable bases, and significantly low content of available phosphorus. The PH, organic matter, and available phosphorus of the soils in northern Jeju are 6.1, 12.6%, and 23 ppm, while those of the soils in the southern Jeju are 6.4, 3.7 %, and 76 ppm respectively. Upland soils in Jeju may be classified into 4 groups on the basis of soil fertility: black soil, very dark brown soil, dark brown, and red yellow soil. The organic matter content of black soil, very dark soil and dark brown soil is 15%, 7%, and 3% respectively. The soils of high organic matter content show the high phosphorus absorption coefficient, low content of available phosphorus, and low degree of the base saturation. The soil productivity for barley in the northern Jeju is higher than that in the southern Jeju and the productivity in the western Jeju is higher than that in the eastern part. The productivity for barley is in decreasing order of dark brown soil, very dark brown soil and black soil. Yields of potato and sweet potato in Jeju are higher than in the mainland. Those crops are considered to be tolerant to aluminumtoxicity. The response of sweet potato to nitrogen, phosphorus, and potassium in Jeju soils is lower than that in the mainland, while the response of barley and rape to nitrogen and phosphorus is higher than that in the mainland. The response to fertilizer applied is greater in the northern Jeju than in the southern Jeju. Lime requirement for the Jeju soils calculated on the basis of laboratory tests is so tremendous that single application of lime required might induce adverse effect. Most of the phosphorus applied to the Jeju soils is readily fixed as unavailable form and application of phosphorus in the level of 30 to 40 kg/10a is thought to give little effect.

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A Pilot Study of Evaluating the Reliability and Validity of Pattern Identification Tool for Insomnia and Analyzing Correlation with Psychological Tests (불면증 변증도구 신뢰도와 타당도 평가 및 심리검사와의 상관성에 대한 초기연구)

  • Jeong, Jin-Hyung;Lee, Ji-Yoon;Kim, Ju-Yeon;Kim, Si-Yeon;Kang, Wee-Chang;Lim, Jung Hwa;Kim, Bo Kyung;Jung, In Chul
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.1
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    • pp.1-12
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    • 2020
  • Objectives: The purpose of this study was to evaluate the reliability and validity of the instrument on pattern identification for insomnia (PIT-Insomnia) and verify the correlation between PIT-Insomnia and psychological tests. Methods: Two evaluators examined the pattern identification of the participants who met insomnia disorder diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition (DSM-5) and took the Insomnia Severity Index (ISI) score over 15 once manually and twice using the PIT-Insomnia to measure the inter-rater and test-retest reliability. We also conducted the following surveys: the Pittsburgh Sleep Quality Index (PSQI), the Korean version of Beck's depression inventory (K-BDI), the Korean version of the State-Trait Anxiety Inventory (STAI-K), the Korean Symptom checklist-95 (KSCL-95), and the EuroQol-5 dimension (EQ-5D), to measure concurrent validity and correlation between the PTI-Insomnia and psychological tests. Results: 1. The test-retest reliability analysis of the pattern identification results showed moderate agreement, and test-retest reliability analysis of each pattern identification score showed agreements from poor to moderate. 2. The inter-rater reliability analysis of the pattern identification results via manual showed slight agreement, when analysis was performed with calibration, the inter-rater reliability analysis of the pattern identification results via manual showed fair agreement. 3. The concordance analysis between results via manual and the PIT-Insomnia showed poor agreement, when the analysis was performed with calibration, concordance analysis showed fair agreement. 4. The concordance analysis between the PIT-Insomnia and the PSQI showed positive linear correlation. 5. The concordance analysis between the PIT-Insomnia and the PSQI, K-BDI, STAI-K, KSCL-95, and EQ-5D showed that non-interaction between the heart and kidney have positive linear correlation with the K-BDI, anxiety item of KSCL-95, dual deficiency of the heart-spleen have positive linear correlation with somatization item of KSCL-95, paranoia item of KSCL-95, heart deficiency with timidity have positive linear correlation with stress vulnerability item of KSCL-95, parania item of KSCL-95, phlegm-fire harassing the heart have positive linear correlation with K-BDI, paranoia item of KSCL-95, depressed liver qi transforming into fire have positive linear correlation with the anxiety item of KSCL-95, parania item of KSCL-95, all pattern identification have negative linear correlation with EQ-5D. Conclusions: The PIT-Insomnia has moderate agreement of reliability and reflects the severity of insomnia since it has some concurrent validity with the PSQI. There are some correlations between the PTI-Insomnia with specific psychological tests, so we could suggest it can be used appropriately in the clinical situation.

Ecological Characteristics of Digitaria sanguinalis in Temperate Climate (바랭이의 생태적(生態的) 특성(特性)에 관한 연구(硏究))

  • Shin, D.H.;Kim, K.U.
    • Korean Journal of Weed Science
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    • v.3 no.1
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    • pp.29-38
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    • 1983
  • Growth habit, intraspecific competition of Digitaria sanguinalis, and interspecific competition between soybean and D. sanguinalis were evaluated to obtain the basic informations on establishing an effective control measure in upland corps. The earlier planting on April 1 produced approximately 3.5 times higher dry matter than that of the latest planting on July 22 and resulted in the earliest heading on July 8 and the latest heading was observed on September 4 planted on July. 22, but the interval between planting and heading dates was shortened progressively as the planting dates were delayed, showing irregularity of heading within a hill. Tiller numbers per plant were inhibited as densities increased from one to forty. One plant planted per pot produced significantly higher tiller numbers than density of 5 to 40 plants per pot. However, total tiller numbers was the highest in density of 40 plants planted per pot. Regardless of planting densities used, D. sanguinalis at all densities produced the similar dry matter per pot, showing severe intraspecific competition as density increased, but on each plant basis dry weight production was the highest in the lowest density such as one plant planted per pot. Competition between soybean and D. sanguinalis for the entire growing season decreased the total dry weight of soybean by 59.6%. Soybean required the maintenance of a weed free condition, about 3 to 4 weeks immediately after seeding, for obtaining the maximum yield, beyond which soybean crops effectively suppressed the growth of D. sanguinalis.

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Weed Flora of Ulreung Island in Korea (울릉도(鬱陵島)에 발생(發生)하는 잡초종(雜草種))

  • Kim, K.U.;Kwon, S.T.;Lee, I.J.;Kim, S.H.
    • Korean Journal of Weed Science
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    • v.7 no.3
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    • pp.265-279
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    • 1987
  • About 140 weed species belonging to 42 families occurring in summer were observed in Ulreung island. The Compositae was the most wildely occurring family covering 27 weed species, followed by 21 species in Graminae, 9 in Polygonaceae, 7 in Leguminosae, and 7 in Labiatae etc. In terms of the lands classified, about 60 species in 26 families were observed in the cultivated and the medical crops grown areas, respectively, and 116 species in 40 families occurred in the non-cultivated land like the vicinity of the cultivated area and 94 species in 34 families in the valley. No. of species and families were much greater in the non-cutivated land than those of the cultivated one. The most dominant weed species in both the cultivated and its vicinity in Ulreung island were Digitaria sanguinalis, followed by Portulaca oleracea, Polygonum hydropiper, Equisetum arvensis, Artemisia princeps, Commetina communis, Setaria viridis in order. Community analysis was done by the method of Toyohara in two cultivated lands such as the general crop land and the medical herb crop grown land, and two non-cultivated areas such as the vicinity of the cultivated land and valley. The cultivated land consisted of the communites of P. hydropiper and Cyperus amuricus, including Bidens tripartita in P. hydropiper community. The medical crop grown land composed of three major communities like P. hydropiper, Amaranthus mangostanus and Sonchus asper in which A. mangostanus and S. media were presented in the ecoton, indicating community being transiting. In the non-cultivated areas like the vicinity of crop land, the communities of Erigeron annuus, P. oleracea, and Oxalis corniculata were dominant, and Dystaenia takeshimana was included in the community of E. annuus and Stellan'a aquatica in P. oleracea community. In the valley, Ranunculus quelpaertensis community was existed in between the communities of Sonchus asper and Plantago asiatica.

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The Effect of Contamination of Ion Source on Ionic Current of Quadrupole Mass Spectrometer (사중극 질량 분석기의 이온소스 오염이 이온전류에 미치는 영향)

  • Lee, K.C.;Park, C.J.;Kim, J.T.;Oh, E.S.;Hong, K.S.;Hong, S.S.;Lim, I.T.;Yun, J.Y.;Kang, S.W.;Shin, Y.H.
    • Journal of the Korean Vacuum Society
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    • v.18 no.3
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    • pp.197-202
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    • 2009
  • The long term stability of ion current of QMS has been one of key parameters for monitoring gas process in vacuum. The time dependence of ionic current was monitored while the pressure of nitrogen gas was kept at a fixed pressure by introducing the gas into vacuum chamber. The chamber was evacuated to ${\sim}3{\times}10^{-9}\;Torr$ to reduce background signals before the measurement. Two ion sources were tested; one had brownish or black color due to gas contamination and the other one was new, i.e. cleaner. At a nitrogen pressure of $1{\times}10^{-5}\;Torr$, the ionic currents measured by the contaminated ion source decreased faster with time. The decrease rate was respectively ${\sim}46%$ for cleaner one and ${\sim}84%$ for contaminated one after ${\sim}5.5%$ hours. In order to test the effect of filament material on the ion current decrease, we fabricated a tungsten(W) filament which consisted of two parts; one half was made of W and the other was coated with yttria. The similar decrease of ionic currents were shown for the two types of filaments, indicating that slight change of temperature of filament due to material difference i.e. baking effect could not improve the origin of ionic current decrease. Overall the decreasing rate of ionic current is more closely associated with contaminated ion source of QMS rather than its filament materials.

Bioactivities and Isolation of Functional Compounds from Decay-Resistant Hardwood Species (고내후성 활엽수종의 추출성분을 이용한 신기능성 물질의 분리 및 생리활성)

  • 배영수;이상용;오덕환;최돈하;김영균
    • Journal of Korea Foresty Energy
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    • v.19 no.2
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    • pp.93-101
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    • 2000
  • Wood of Robinia pseudoacacia and bark of Populus alba$\times$P. glandulosa, Fraxinus rhynchophylla and Ulmus davidiana var. japonica were collected and extracted with acetone-water(7:3, v/v) in glass jar to examine whether its bioactive compounds exist. The concentrated extracts were fractionated with hexane, chloroform, ethylacetate and water, and then freeze-dried for column chromatography and bioactive tests. The isolated compounds were sakuranetin-5-O-$\beta$-D-glucopyranoside from Populus alba $\times$Pl glandulosa, 4--ethyoxy-(+)-leucorobinetinidin frm R. pseudoacacia and fraxetion from F. rhynchophylla and were characterized by $^1H$ and$^{13}C $ NMR and positive FAB-MS. Decay-resistant activity was expressed by weight loss ratio and hyphae growth inhibition in the wood dust agar medium inoculated wood rot fungi. R. pseudoacacia showed best anti-decaying property in both test and its methanol untreated samples, indicating higher activity than methanol treated samples in hyphae grwoth test. In antioxidative test, $\alpha$-tocopherol, one of natural antioxidants, and BHT, one of synthetic antioxidants, were used as references to cmpare with the antioxidant activities of the extacted fractions. Ethylacetate fraction of F. rhynchophylla bark indicated the hightest activity in this test and all fractions of R. pseudiacacia extractives also indicated higher activities compared with the other fractions. In the isolated compounds, aesculetin isolated from F. rhynchophylla bark showed best activity and followed by robonetinidin from R. pseudoacaica.

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The effects of polishing technique and brushing on the surface roughness of acrylic resin (연마 방법과 칫솔질이 아크릴릭 레진의 표면 거칠기에 미치는 영향)

  • Lee, Ju-Ri;Jeong, Cheol-Ho;Choi, Jung-Han;Hwang, Jae-Woong;Lee, Dong-Hwan
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.4
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    • pp.287-293
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    • 2010
  • Purpose: This study evaluated the effect of polishing techniques on surface roughness of polymethyl methacrylate (PMMA), as well as the influence of light-cured surface glaze and subsequent brushing on surface roughness. Materials and methods: A total of 60 PMMA specimens ($10{\times}10{\times}5\;mm$) were made and then divided into 6 groups of 10 each according to the polymerization methods (under pressure or atmosphere) and the surface polishing methods (mechanical or chemical polishing) including 2 control groups. The mechanical polishing was performed with the carbide denture bur, rubber points and then pumice and lathe wheel. The chemical polishing was performed by applying a light-cured surface glaze ($Plaquit^{(R)}$; Dreve-Dentamid GmbH). Accura $2000^{(R)}$, a non-contact, non-destructive, optical 3-dimensional surface analysis system, was used to measure the surface roughness (Ra) and 3-dimensional images were acquired. The surface roughness was again measured after ultrasonic tooth brushing in order to evaluate the influence of brushing on the surface roughness. The statistical analysis was performed with Mann-Whitney test and t-test using a 95% level of confidence. Results: The chemically polished group showed a statistically lower mean surface roughness in comparison to the mechanically polished group (P = .0045) and the specimens polymerized under the atmospheric pressure presented a more significant difference (P = .0138). After brushing, all of the groups, except the mechanically polished group, presented rougher surfaces and showed no statistically significant differences between groups. Conclusion: Although the surface roughness increased after brushing, the chemical polishing technique presented an improved surface condition in comparison to the mechanical polishing technique.

Factors Controlling Some Physicochemical Properties of Bentonite (벤토나이트의 물리-화학적 성질을 지배하는 요인분석)

  • 고상모;손병국;송민섭;박성환;이석훈
    • Journal of the Mineralogical Society of Korea
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    • v.15 no.4
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    • pp.259-272
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    • 2002
  • This study was tried to interpret the important major factors controlling some physicochemical properties by comparing mineralogical and physicochemical characteristics such as pH, cation exchange capacity, Methylene Blue adsorption amount, swelling, viscosity, strength (compressional and tensile), and surface area etc. Investigated bentonite samples are five Korean samples from Dusan, Naa, Oksan, Dongyang, and Yeonil deposits and two Japanese bentonites from Tsukinuno and Tomioka deposits which were formed under a similar geological environment of the Tertiary basin. Tsukinuno bentonite is only natural Na-type bentonite and the others are all Ca-type bentonites. Most of the properties are not explained by the montmorillonite content only though the most important factor controlling the physicochemical properties is the montmorillonite content. The layer charge of montmorillonite will strongly control cation exchange capacity and Methylene Blue adsorption. Zeolite bearing bentonites show the strong alkaline character and causes the increase of cation exchange capacity, however decrease swelling, viscosity and strengths. Pyrite bearing bentonites decrease green compressional strength and wet tensile strength. The exchangeable interlayer cations control some physicochemical properties. Na-type bentonite than Ca-type shows more strong alkaline character and much more advanced swelling and viscosity. Also the size and thickness of montmorillonite flakes seem to control some physicochemical properties. Bentonite mainly composed of montmorillonite of very thin and large flakes is characterized by the very high surface area, cation exchange capacity, viscosity, swelling, Methylene Blue adsorption, green compressional strength and wet tensile strength. Domestic Dusan bentonite shows the most excellent physicochemical properties, which is due to the high content(84%) and very well crystallinity of montmorillonite.