• Proceedings of the Korean Operations and Management Science Society Conference
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• 1991.10a
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• pp.261-267
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• 1991

다품종소량생산의 특징을 갖고 있는 금형공업에서 컴퓨터통합생산시스템(Computer Integrated Manufacturing System;CIMS)의 실현을 위한 중요한 분야의 하나는 부품설계도면으로부터 최종제품을 생산하는데 필요한 공정계획의 자동화, 즉 컴퓨터를 이용하여 공정계획을 자동적으로 생성하는 자동공정계획시스템(Computer Aided Process Planning;CAPP) 기술의 개발이다. 국내외적으로 CAPP분야의 연구는 컴퓨터 지원에 의한 자동화 기술의 급속한 발전과 더불어 지난 20여년 동안에 기계가공품에 관한 CAPP은 약 150여가지가 개발되었으나, 이는 컴퓨터 지원에 의한 설계의 자동화(Computer Aided Design;CAD)나 컴퓨터 지원에 의한 제조의 자동화(Computer Aided Manufacturing;CAM)분야에 비해 상대적으로 저조한 형편이다. 특히 금형을 대상으로 한 CAPP시스템의 개발은 아직 초기단계에 있기 때문에, 본 연구에서는 사출금형을 대상으로 하여 실용성이 있는 공정설계시스템을 개발함을 목적으로 한다. 일반적으로 공정계획은 "소재로부터 제품을 경제적, 효율적으로 생산하는데 필요한 제조공정의 체계적인 결정"이라고 정의할 수 있다. 공정계획은 제품의 종류와 수량, 재료와 부품의 종류, 보유 생산설비와 제조기술의 수준에 따라 다르나, 공정설계(Process Design)와 작업설계(Operation Design)로 구분할 수 있다. 본 연구에서는 공정계획을 광의의 공정설계로 정의하고, 공정설계와 공정계획을 동의어로 통용토록 한다. 기존의 CAPP시스템의 개발에 관한 기본적인 접근방법은 변성형방법(Variant method), 창성형방법(Generative method) 및 자동화방법(Automatic method)이 있다. 이들 CAPP시스템을 개발할 때 사용하는 기법은 크게 5가지- (1) GT(group Technology) 접근기법, (2) Bottom-up 접근기법, (3) Top-down 접근기법, (4) AI와 전문가시스템(Expert System) 접근기법, (5) 컴퓨터 프로그래밍 언어 - 로 분류할 수 있다. 본 연구에서는 전문가시스템 기법을 도입해서 사출금형 공정계획전문가의 지식과 경험을 획득하여 지식베이스를 구축하고, 전문가시스템 셀(shell)중 CLIPS를 이용하여 자동공정계획시스템인 Mold CAPP을 개발하였다.PP을 개발하였다.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.747-752
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• 2013

Oncostatin M (OSM) is a multifunctional cellular regulator acting on a wide variety of cells, which has potential roles in the regulation of gene activation, cell survival, proliferation and differentiation. Previous studies have shown that OSM can induce morphological and/or functional differentiation and maturation of many tumor cells. However, the action of OSM on the induction of differentiation of human hepatocellular carcinoma (HCC) has not been reported. Here, we investigated the effects of different concentrations of OSM on human HCC cell line SMMC-7721 growth, proliferation, cell cycling, apoptosis and differentiation in vitro. Cell growth was determined via MTT assay, proliferation by cell cycle analysis, apoptosis by flow cytometry, morphology by transmission electronic microscopy, and cell function by detection of biochemical markers. Our results demonstrated that OSM strongly inhibited the growth of SMMC-7721 cells in a dose-dependent manner, associated with decreased clonogenicity. Cell cycle analysis revealed a decreased proportion of cells in S phase, with arrest at G0/G1. The apotosis rate was increased after OSM treatment compared to the control. These changes were associated with striking changes in cellular morphology, toward a more mature hepatic phenotype, accompanied by significant reduction of the expression of AFP and specific activity of ${\gamma}$-GT, with remarkable increase in secretion of albumin and ALP activity. Taken together, our findings indicate that OSM could induce the differentiation and reduce cell viability of SMMC-7721 cells, suggesting that differentiation therapy with OSM offers the opportunity for therapeutic intervention in HCC.

• Restorative Dentistry and Endodontics
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• v.24 no.4
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• pp.633-638
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• 1999

The purpose of our study is to evaluate the ability of nickel-titanium(NiTi) files in maintaining the original curvature of a curved root canal during canal preparation. Curved canals on translucent resin blocks were prepared with Profiles and stainless steel files and they were placed at the platform which can reproduce the same position. The unprepared and prepared canal forms were accurately compared by double exposure technique of photography. The results were as follows : 1 NiTi files made a canal comparatively taper, but stainless steel files didn't make a canal taper, wicest at midportion and comparatively wide at a apical portion. 2. Canals preparations with no. 25 Profile.06 up to the working length were most excellent in taperness and in maintaining the original curvature. Canals prepared with no 30 Profile.06 up to the working length made a little outer transportation at a apical portion, but not severe. 3. Canal preparations with Profile GT were excellent in taperness and in maintaining the original curvature, but made more enlargement toward the inner side at the starting portion of the curvature. 4. Canal preparations with stainless steel files were not tapered and provided the largest transportation.

• Journal of Korean Biological Nursing Science
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• v.17 no.2
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• pp.104-113
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• 2015

Purpose: This study aimed to analyze physical activity as measured by the International Physical Activity Questionnaire (IPAQ) and an actigraph in breast cancer survivors, as well as to identify their intention to participate in a physical activity program. Methods: Breast cancer patients who had been diagnosed for more than six months (N=135) at a university hospital participated from June 2012 to May 2013. Physical activity was measured using the Korean version of the IPAQ-Short Form and Actigraph GT3X plus an accelerator for seven consecutive days. Data analyses were conducted using the SPSS WIN 19.0 program. Results: Mean total physical activity was 2298.21 metabolic equivalent task (MET)-min/week as assessed by IPAQ and 150,140.57 counts/day as measured by an actigraph. There were statistically significant correlations between moderate physical activity from IPAQ and light intensity of physical activity from the actigraph (r=.735, p<.001), vigorous physical activity from IPAQ and vigorous intensity of physical activity from the actigraph (r=.871, p<.001), total physical activity from IPAQ and light intensity of physical activity from the actigraph (r=.825, p<.001), respectively. Most (80.7%) cancer survivors reported a positive attitude toward physical activity and 57.8% expressed a willingness to participate in a physical activity program. More than half (60%) of the subjects preferred walking, 80.6% preferred more than 30 minutes of exercise, and 57.1% wanted to engage in physical activity three times a week and preferred home-based activities. Perceived barriers included fatigue, lack of strength and pain. Conclusion: It is necessary to consider intensity, personal preferences, and patient-perceived barriers when developing physical activity programs for breast cancer survivors.

• Proceedings of the KACD Conference
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• 2003.11a
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• pp.547-547
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• 2003

The aim of this study was to compare the effects of three Ni-Ti instruments on leaning ability by evaluating the volumetric and morphological changes in the apical 6mm of the root canals before and after preparation, using three-dimensionally reconstructed root canals of extracted human teeth. Forty-five teeth were used in this study. They were opened the chambers and removed the all pulp remnants ultrasonically. Subsequently, the canal wall was coated with silver paste and prepared using ProTaper, ProFile and GT rotary files according to the manufacturers instructions. Before and after root canal preparation, all the specimens were scanned with micro computed tomography and examined the differences in dentine volume removed, canal straightening, the proportion of the unchanged area and canal transportation. Quantitative analysis revealed that instrumentation increased in canal volume ranging between 0.081 and $1.866{\;}\textrm{mm}^3$. On average, the large apical preparation produced by ProTaper demonstrated smaller proportions of unchanged surface areas compared to the two other instruments in small canals. But in large canals like maxillary central incisor, the preparation of ProTaper instruments was not enough. ProTaper instrument was tended to increase more in canal volume as compared with the other two instruments but unchanged area was no significant difference. These results showed that three instruments had similar preparation ability and micro computed tomography in combination with the coated wall of root canal using silver paste is a nondestructive and valuable tool to study root canal geometry and changes after preparations in detail.

• Journal of Preventive Medicine and Public Health
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• v.52 no.2
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• pp.101-108
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• 2019

Objectives: To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer. Methods: A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines. Results: Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations. Conclusions: Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.

• The Korean Journal of Mycology
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• v.49 no.1
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• pp.33-44
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• 2021

Lentinula edodes (Berk.) Pegler, the most produced mushroom in the world, is an edible mushroom with very high nutritional and pharmacological value. Currently, interest in the protection of genetic resources is increasing worldwide, and securing the distinction between new cultivars is very important. Therefore, the development of efficient molecular markers that can discriminate between L. edodes cultivars is required. In this study, we developed cleaved amplified polymorphic sequence (CAPS) markers for the identification of L. edodes cultivars (Sanbaekhyang and Sulbaekhyang). These markers were developed from whole genome sequencing data from L. edodes monokaryon strain B17 and resequencing data from 40 cultivars. A nucleotide deletion existed in scaffold 19 POS 214449 in Sanbaekhyang (GT→G), and a single nucleotide polymorphism changed in scaffold 7 POS 215801 in Sulbaekhyang (G→A). The restriction enzymes Hha I and HpyCH4IV distinguished Sanbaekhyang and Sulbaekhyang, respectively, from other cultivars. Thus, we developed two CAPS markers for the identification of the L. edodes cultivars Sanbaekhyang and Sulbaekhyang.

• Journal of the Korea Society of Computer and Information
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• v.26 no.1
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• pp.93-101
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• 2021

In this paper, a vehicle license plate detection scheme is proposed that uses the spatial attention areas to detect accurately the license plates in various real-road situations. First, the previous WPOD-NET was analyzed, and its detection accuracy is evaluated as lower due to the unnecessary noises in the wide detection candidate areas. To resolve this problem, a vehicle license plate detection model is proposed that uses the candidate area of the license plate as a spatial attention areas. And we compared its performance to that of the WPOD-NET, together with the case of using the optimal spatial attention areas using the ground truth data. The experimental results show that the proposed model has about 20% higher detection accuracy than the original WPOD-NET since the proposed scheme uses tight detection candidate areas.

• Journal of Korean Biological Nursing Science
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• v.23 no.4
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• pp.287-297
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• 2021

Purpose: This study aimed to evaluate the correlation and agreement of physical activity (PA) between data obtained from wearable Actigraph devices and self-reporting questionnaires, and to investigate the relationship between psychological state (depression, anxiety, and fatigue) and PA. Methods: A descriptive study was conducted using physical measurements and surveys. PA was measured through both the International Physical Activity Questionnaire (IPAQ) and the Actigraph GT3X+ device. The demographic characteristics of the subjects, as well as their depression, anxiety, and fatigue scores, were collected with structured questionnaires. The Spearman's rank correlation coefficient and the Bland-Altman plot method were employed. Results: Data from 36 healthy adults were analyzed. The overall levels of PA measured using the IPAQ and the Actigraph were 1,891.69 MET min/week and 669.96 MET/day, respectively. Total levels of PA did not show a significant correlation between the two measurement methodologies. However, the moderate-intensity PA resulting from the IPAQ scores showed a significant positive correlation with the light-intensity PA recorded by the Actigraph. The Bland-Altman plot analysis demonstrated that the levels of PA as measured by the two different methods did not match. In addition, PA measured using the Actigraph showed a significant negative correlation with depression and anxiety whereas PA measured using the IPAQ showed a significant positive correlation with fatigue. Conclusion: The conclusion of this study is that the data obtained from the subjective self-reporting questionnaire and the wearable Actigraph do not correlate or match in healthy adults. Future research should investigate the relationship between depression and PA intensity through the Actigraph, or other wearable devices equipped with smartphone apps.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.59 no.4
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• pp.336-343
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• 2023

The aging fishery training vessels from the past have mostly been decommissioned, and many universities are introducing state-of-the-art large fishery training vessels. The purpose of these training vessels is to train marine professionals and above all, safety to prevent marine accidents should be of utmost priority as many students embark on the vessel. This study estimated the impact of the hydrodynamic interaction forces acting on the model vessel (fishery training vessel) from the bank when the vessel pass near the semi-circle bank wall in various conditions through the numerical calculation, especially concerning maneuvering motions of the vessel. For estimation, variables were mainly set as the size of the semi-circle shape, the lateral distance between the bank and the model vessel, and the depth near the bank. As a result, it was estimated that, in order for the model vessel to safely pass the semi-circle bank wall at a speed of 4 knots, the water depth to the vessel draft ratio should be 1.5 or more (approximately 8 m of water depth), and the lateral distance from the semi-circle bank wall should be 0.4 times the model vessel's length (L_pp) or more (a distance of 34 m or more). Under these conditions, it was expected that the model vessel would pass without significantly being affected by the bank wall.