• Asian-Australasian Journal of Animal Sciences
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• 제20권2호
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• pp.166-171
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• 2007

The objective of this study was to assess the association of polymorphisms in ${\kappa}$-cn, ${\beta}$-lg, ${\beta}$-lg 5′ flanking region, CSN1S2, and IGFBP-3 genes with milk production traits and mastitis-related traits in Chinese Holstein. Traits analyzed were 305 day standard milk yield, protein percentage, fat percentage, the ratio of fat percentage and protein percentage, pre-somatic cell count, somatic cell count, and somatic cell score, respectively. CSN1S2 locus was uninformative because only one genotype BB was found in Chinese Holstein. Allele frequencies of A and B in IGFBP-3 gene were 0.5738 and 0.4262 in Chinese Holstein population, which was different from reported Qinchuan cattle population. The genotypes of animals at IGFBP-3 locus significantly affected 305 day standard milk yield, protein percentage, and somatic cell score. The ${\beta}$-lg genotypes had a significant effect on protein percentage and the ratio of fat percentage and protein percentage. Polymorphism in ${\beta}$-lg 5′ flanking region was associated with 305 day standard milk yield, protein percentage, fat percentage, pre-somatic cell count, and somatic cell count. No significant associations of the polymorphism in ${\kappa}$-cn gene were observed for any trait.

• 대한의생명과학회지
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• 제24권4호
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• pp.418-425
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• 2018

Amyloid brain positron emission tomography (PET) images are visually and subjectively analyzed by the physician with a lot of time and effort to determine the ${\beta}$-Amyloid ($A{\beta}$) deposition. We designed a convolutional neural network (CNN) model that predicts the $A{\beta}$-positive and $A{\beta}$-negative status. We performed 18F-florbetaben (FBB) brain PET on controls and patients (n=176) with mild cognitive impairment and Alzheimer's Disease (AD). We classified brain PET images visually as per the on the brain amyloid plaque load score. We designed the visual geometry group (VGG16) model for the visual assessment of slice-based samples. To evaluate only the gray matter and not the white matter, gray matter masking (GMM) was applied to the slice-based standard samples. All the performance metrics were higher with GMM than without GMM (accuracy 92.39 vs. 89.60, sensitivity 87.93 vs. 85.76, and specificity 98.94 vs. 95.32). For the patient-based standard, all the performance metrics were almost the same (accuracy 89.78 vs. 89.21), lower (sensitivity 93.97 vs. 99.14), and higher (specificity 81.67 vs. 70.00). The area under curve with the VGG16 model that observed the gray matter region only was slightly higher than the model that observed the whole brain for both slice-based and patient-based decision processes. Amyloid brain PET images can be appropriately analyzed using the CNN model for predicting the $A{\beta}$-positive and $A{\beta}$-negative status.

• 한국산학기술학회논문지
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• 제18권6호
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• pp.356-365
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• 2017

본 연구의 목적은 간호사의 대인관계문제, 감정노동, 전문직 자아개념의 정도와 관계를 확인하고 이들 변수가 전문직 자아개념에 미치는 영향을 파악하기 위함이다. 충청도 소재 1개 병원에 재직 중인 간호사 150명을 대상으로, 2016년 8월 2일부터 8월 30일까지 자가 보고식 설문조사로 시행되었다. 연구결과, 대인관계문제 평균점수는 2.57점으로 사람들에게 향함의 점수가 가장 높았으며, 감정노동은 3.50점으로 감정노동 빈도가 가장 높았다. 전문직 자아개념의 평균점수는 2.54점으로 의사소통의 점수가 가장 높게 나타났다. 대인관계문제는 감정노동(r=.392, p<.001)과 통계적으로 유의한 양의 상관관계를 보였으며, 전문직 자아개념은 대인관계문제(r=-.452, p<.001)와 감정노동(r=-.376, p<.001)과 통계적으로 유의한 음의 상관관계가 있는 것으로 나타났다. 대상자의 전문직 자아개념에 대인관계문제(${\beta}=-0.377$, p<.001)가 가장 큰 영향력을 나타내는 변수였으며, 연령(40세 이상)(${\beta}=0.435$ p<.001), 연령(30세 이상 40세 미만)(${\beta}=0.278$ p<.001), 학력(${\beta}=0.157$ p=.012), 감정노동(${\beta}=-0.153$ p=.025) 순으로 영향을 주는 것으로 나타났으며, 이들 전체 변수는 전문직 자아개념에 대해 약 44%의 설명력을 나타냈다(F=24.38, p<.001). 그러므로 대인관계문제 및 감정노동을 감소시키기 위한 전략이 간호사의 전문직 자아개념 향상을 위해 도움이 될 것으로 사료된다.

• 한국간호교육학회지
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• 제22권1호
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• pp.83-95
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• 2016

Purpose: This study aims to identify perception, performance, and the related factors of performance in regards to patients' medical information protection among allied health college students. Methods: Four hundred twelve subjects from three colleges located in Jeonbuk and Kyungbuk province consented to participate. Data was collected from November 28 to December 15, 2012. To assess perception and performance in regards to patients' medical information protection, a self-reporting questionnaire was used. Data was analyzed via SPSS 18.0 program. Results: The score of perception and performance about patients' medical information protection were 4.07 and 3.56, respectively. All item's scores of performance were significantly lower than those of perception. The perception score was significantly different according to recognition of hospital ethics code (t=1.95, p=.052), and recognition of association ethics code (t=2.88, p=.004). The performance score was significantly different according to gender (t=-3.32, p=001), major (F=14.41, p<.001), clinical practicum hospitals (F=8.22, p<.001), and method of electronic medical record access (F=3.23, p=.023). The factors influencing performance were perception(${\beta}=.46$, p<.001), duration of clinical practice(${\beta}=-.36$, p<.001), and gender(${\beta}=.09$, p=.033). Conclusion: In order to improve performance in regards to patients' medical information protection of allied health college students, we should develop ethical education programs and standardize them through multidisciplinary collaboration.

• 한국간호교육학회지
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• 제25권1호
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• pp.148-158
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• 2019

Purpose: This study is a descriptive study to explore the effects of work performance, perceived organization support, and personal coping resources on job satisfaction of infusion nurses in Korea. Methods: The participants of this study were 155 infusion nurses in 19 general hospitals and advanced general hospitals in Korea. Data were collected from January to March 2018 using a structured questionnaire and analyzed with the SPSS software version 23. Results: The participants' job satisfaction score was 3.01, their work performance score was 3.60, their perceived organization support score was 2.83, and their personal coping resources score was 3.53. The regression model for job satisfaction was significant (F=56.10, p<.001), and the total explanatory power was 52%. The variables affecting job satisfaction were personal coping resources (${\beta}=.44$, p<.001), perceived organization support (${\beta}=.42$, p<.001), and working locations (${\beta}=.13$, p=.028). Conclusion: To increase job satisfaction of infusion nurses, boosting strategies for personal coping resources, perceived organization support, and examination of work performance characteristics of each local area should be considered. In addition, development of customized programs is needed, focusing on infusion nurse personnel and job characteristics.

• 전기학회논문지
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• 제63권7호
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• pp.968-975
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• 2014

This paper proposed a evaluation method for individual's subjective preferred location using EEG and emotional assessment. Visual stimulus were sequentially presented a total six points(the top and the bottom of the left, the top and the bottom of the center and the top and the bottom of the right on the screen). EEG were measured from twenty subjects according to each six points. At the same time, we were executed evaluation of subjects preferred location from emotional assessment. Alpha and beta wave were measured in Fp1, Fp2, F7 and F8 location, followed by ten to twenty electrode system. Correlations and variations of alpha and beta wave from each channel were calculated and analyzed. Because of the number of subjects population under 30, we used Speareman test for a correlation analysis between alpha and beta wave. Also, emotional assessments which compose of visual sense harmony, visual sense stability, stability of position and the visibility were performed and were analyzed by average and frequency. After visual stimulus, emotional assessments were performed. From the variance analysis of EEG, beta wave from F7 was appeared statistically significant as significance probability of 0.006. Also, between alpha wave and beta wave appeared a negative correlation(r=-0.190). From the post-hoc test of F7 beta wave, location 1, 5 and 6 appeared to difference statistically significant. Emotional assessment result according to six positions showed 0.00 significance probability. Thus, location and emotional assessment appeared to influence on each other. From the average and frequency analysis of emotional assessment, location 2 showed obtained of best emotional assessment score and appeared lower beta wave than other locations. Finally, most subjects showed a preference for location 2. Through obtained results in this paper, will be helpful to about human emotional assessment and EEG research.

• 한국산학기술학회논문지
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• 제14권11호
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• pp.5672-5681
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• 2013

본 연구의 목적은 일개 대학 간호대학생의 생명의료윤리의식 정도를 검증하기 위한 연구이다. 연구대상은 간호학생 총 266명이며, 자료수집은 2012년 9월 10일부터 10월 5일까지였다. 생명의료윤리의식의 총점 평균은 4점 만점을 기준으로 2.98(${\pm}0.2$)점이었으며, '태아생명권' 점수가 3.27(${\pm}0.5$)로 가장 높은 점수를, '장기이식'에서 2.70(${\pm}0.4$)로 가장 낮은 점수를 보였다. 윤리적 가치관이 매우 확고한 경우 3.06점으로 가장 높았으며(F=3.936, p=.021), 인공임신이 3.21점으로 가장 높은 점수를 나타냈다(F=5.001, p=.007). 성별과 생명의료윤리의식 점수(r=0.180, p=.003), 윤리적 가치관은 정적 상관관계를 보였다(r=0.170, p=.005). 간호대학생의 생명의료윤리의식에 대한 예측 요인은 성별(${\beta}$=0.205, t=3.399, p=<.001)생명과학 발달에 따른 윤리적문제점 증가에 대한 우려(${\beta}$=0.142, t=2.261, p=0.025)와 윤리적 가치관 (${\beta}$=0.189, t=3.119, p=0.002)이었다. 본 연구결과를 토대로 간호학생들의 생명의료윤리의식을 높이기 위한 교육 프로그램을 마련하는 데 기초자료가 될 수 있을 것으로 기대된다.

• 대한약침학회지
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• 제22권3호
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• pp.166-170
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• 2019

Objectives: Attentional and memory functions are important aspects of neural plasticity that, theoretically, should be amenable to pharmacopuncture treatments. A previous study from our laboratory suggested that quantitative electroencephalographic (qEEG) measurements of theta/beta ratio (TBR), an index of attentional control, may be indicative of academic performance in a first-semester medical school course. The present study expands our prior report by extracting and analyzing data on frontal theta and beta asymmetries. We test the hypothesis that the amount of frontal theta and beta asymmetries (fTA, fBA), are correlated with TBR and academic performance, thereby providing novel targets for pharmacopuncture treatments to improve cognitive performance. Methods: Ten healthy male volunteers were subjected to 5-10 min of qEEG measurements under eyes-closed conditions. The qEEG measurements were performed 3 days before each of first two block examinations in anatomy-physiology, separated by five weeks. Amplitudes of the theta and beta waveforms, expressed in ${\mu}V$, were used to compute TBR, fTA and fBA. Significance of changes in theta and beta EEG wave amplitude was assessed by ANOVA with post-hoc t-testing. Correlations between TBR, fTA, fBA and the raw examination scores were evaluated by Pearson's product-moment coefficients and linear regression analysis. Results: fTA and fBA were found to be negatively correlated with TBR (P<0.03, P<0.05, respectively) and were positively correlated with the second examination score (P<0.03, P=0.1, respectively). Conclusion: Smaller fTA and fBA were associated with lower academic performance in the second of two first-semester medical school anatomy-physiology block examination. Future studies should determine whether these qEEG metrics are useful for monitoring changes associated with the brain's cognitive adaptations to academic challenges, for predicting academic performance and for targeting phamacopuncture treatments to improve cognitive performance.

• 감성과학
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• 제16권1호
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• pp.75-84
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• 2013

The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to yoga breathing ($pr{\bar{a}}n{\bar{a}}y{\bar{a}}ma$) have not been systematically explored yet. In this study, the effects of a yoga breathing program on prefrontal EEG were tested with middle-aged women. Participants were collected as volunteers and controlled into two groups. Two channel EEG was recorded in the prefrontal region (Fp1, Fp2) from the yoga breathing group (n=17) and control group (n=17). QEEG quotients were transformed from the EEGs and analyzed by the ANOVAs on gain scores. As a result, ${\alpha}/{\delta}$ (left, right) and CQ (correlation quotient) for yoga breathing participants were significantly decreased compared to control group (p<.05). ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (left, right) were increased significantly (p<.05). For those significantly changed QEEG quotients, the interaction effects of Group x prefrontal alpha (${\alpha}$) and beta (${\beta}$) asymmetry were tested. Only the ${\alpha}$ asymmetry showed main effect on the gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) with F (1, 34)＝5.694 (p<.05). Pearson's correlation coefficient between ${\alpha}$ asymmetry and gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) was .374 (p<.05). The gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) was increased for the right ${\alpha}$ dominance of yoga breathing group. On the contrary it was decreased for the left ${\alpha}$ dominance of yoga breathing group as well as the control regardless of the dominance. The result of this study implies that yoga breathing increases stress resistance and is effective in the management of physical stress. Emotionally relaxed people may have greater instantaneous stress reduction after yoga breathing. Moreover, yoga breathing could be also beneficial for depressed who may be more vulnerable to stress.

• Journal of Korean Biological Nursing Science
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• 제19권2호
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• pp.113-122
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• 2017

Purpose: The purpose of this study was to identify influencing factors on rehabilitation adherence in stroke patients. Methods: This study was a descriptive survey. A structured questionnaire was used for face-to-face interviews with a convenient sample of 192 subjects, who were admitted in 5 rehabilitation hospitals located in G metropolitan city. Results: The score of rehabilitation motivation in the subjects was a mean of $2.04{\pm}0.35$, self-efficacy $6.22{\pm}2.32$, family support $3.40{\pm}0.82$ and rehabilitation adherence $3.08{\pm}0.41$. The rehabilitation adherence was a statistically significant difference according to the education level (F= 3.40, p= .035), marital status (F= 4.04, p= .019), number of personal insurance policies (K= 9.80, p= .020), location of paresis (F= 2.72, p= .046), and status of current smoking (M = 657.00, p= .001). There was significant correlation among degree of rehabilitation adherence, rehabilitation motivation (r= .30, p< .001), self-efficacy (r= .14, p= .046) and family support (r= .18, p= .011). Rehabilitation motivation (${\beta}=0.19$, p= .007), self-efficacy (${\beta}=0.14$, p= .035), marital status (${\beta}=0.14$, p= .038), number of personal insurance policies (${\beta}=-0.15$, p= .045) and location of paresis(${\beta}=-0.15$, p= .028) were identified as significant predictors. This model explained 22.6% of variance in rehabilitation adherence (F= 5.92, p< .001). Conclusion: There is a need to develop an effective intervention for rehabilitation adherence improvement considering the identified variables in this study.