• Title/Summary/Keyword: $C_{}$ f(mean)/

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Characterization and Antiviral Effects of Mx Proteins from Various MHC Haplotype Chickens Showing Different Susceptible to Marek's Disease Virus

  • Chang, Kyuug-Soo
    • Biomedical Science Letters
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    • v.16 no.4
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    • pp.229-238
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    • 2010
  • Chicken Mx protein (cMx) induced interferon (IFN) is an antiviral protein to inhibit replication of RNA virus, particularly negative stranded RNA virus, through blockage of transfortation of viral RNA and proteins. In order to determine antiviral effects of cMx from different MHC haplotype chicken, we characterized cMx gene by studying on nucleotide sequencing, antiviral effects to Newcastle disease virus, VSV and MDV, and transcription activities. Three types of eMx genes (2,118 bp) were detected from the different MHC haplotype chickens [B19 (N), B15(F) and B21 (GSP)] chickens, which have showed different susceptible to Marek's disease (MD). Several amino acid substitutions were showed in the cMx. The amino acid 548 and 631 in the cMxs from N and F, chickens susceptible to MD, was Val and Asn which was important on antiviral effects, and showed in resistant cMx. Those in the cMx from GSP, chicken resistant to MD, were same that showed in susceptible cMx. Though every cMx transactivated the expression of the reporter gene, the transcription activation by resistant cMx from N and F was lower compared to that by susceptible cMx from GSP. The decease of the cell growth in the resistant cMx cloned cells was seen in comparison with another cMx clone cells. Replication of NDV and VSV was suppressed in the clones with resistant cMx from N and F. NMx258-transducted cells lack of antiviral effects, and NMx437 or NMx646-transducted cells was showed 60% of antiviral effects compared to NMx705. Mean death time (MDT) and hemaggutination (HA) titer to NDV was long and low in the eggs of N and F lines, but short and high in the egg of GSP line. Interestingly, strong suppression to NDV was observed in the clone with N-Mx and in the eggs of N line. However, the effects of Mx for replication of vvMDV1 have not been. Thus, resistant types of cMx, N- and F-Mx, have showed the anti-viral effects to only RNA virus including NDV and VSV, but not to DNA virus. Antiviral effects of cMx were required whole length of amino acid including Val and Asn in amino acid 548 and 631.

Prediction of Remaining Useful Life (RUL) of Electronic Components in the POSAFE-Q PLC Platform under NPP Dynamic Stress Conditions

  • Inseok Jang;Chang Hwoi Kim
    • Nuclear Engineering and Technology
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    • v.56 no.5
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    • pp.1863-1873
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    • 2024
  • In the Korean domestic nuclear industry, to analyze the reliability of instrumentation and control (I&C) systems, the failure rates of the electronic components constituting the I&C systems are predicted based on the MIL-HDBK-217F standard titled 'Reliability Prediction of Electronic Equipment'. Based on these predicted failure rates, the mean time to failure of the I&C systems is calculated to determine the replacement period of the I&C systems. However, this conventional approach to the prediction of electronic component failure rates assumes that factors affecting the failure rates such as ambient temperature and operating voltage are static constants. In this regard, the objective of this study is to propose a prediction method for the remaining useful life (RUL) of electronic components considering mean time to failure calculations reflecting dynamic environments, such as changes in ambient temperature and operating voltage. Results of this study show that the RUL of electronic components can be estimated depending on time-varying temperature and electrical stress, implying that the RUL of electronic components can be predicted under dynamic stress conditions.

Nitrogen removal characteristics of pigment wastewater using PAC-A/O process (PAC-A/O 공정을 이용한 안료폐수의 질소 제거 특성)

  • Jeong, Jongsik
    • Journal of Korean Society of Water and Wastewater
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    • v.32 no.1
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    • pp.19-25
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    • 2018
  • The objectives of this study were to evaluate the removal characteristics of total nitrogen, the influence factor of denitrification and the optimum operating condition in the pigment wastewater treatment using PAC-A/O process. The operating conditions of PAC-A/O process were mean BOD volumetric loading $0.86kgBOD/m^3/day$, mean F/M ratio 0.072~0.13 kgBOD/kgMLVSS/day and mean C/N ratio 3.47, respectively. The conditions of anoxic process in the field plant test were mean pH 8.3~8.7 and mean temperature $34.1{\sim}44.0^{\circ}C$. The ORP bending point knee was eventually appeared in the ORP -107 mV and $NO_3{^-}-N$ removal efficiency was increased according to the ORP decrease. In the ORP -107 mV below condition, the removal efficiency of T-N and $NO_3{^-}-N$ was 92.3~95.0% and 98.5~99.7%. Denitrification rate was calculated to be 1.581~1.791 mg $NO_3{^-}-N/gMLSS/hr$. The experimental results showed that the ORP control in the PAC-A/O process could be an effective method for treatment of pigment wastewater.

Chemical Analysis of Water Soluble Aerosols at Kosan, Cheju lsland (제주도 고산에서 수용성 에어로졸의 화학적 성분 분석)

  • 이호근;박경윤;서명석;장광미;강창희;허철구
    • Journal of Korean Society for Atmospheric Environment
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    • v.11 no.3
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    • pp.245-252
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    • 1995
  • Atmospheric aerosols were collected by a High Volume Tape Sampler from March 1992 to December 1993 ar Korean, Cheju, Korea. The water soluble ion concentrations in aerosol were analyzed. The concentrations of cations (N $a^{+}$, $K^{+}$, $Ca^{2+}$, $Mg^{2+}$, N $H_{4}$$^{+}$) were determined by an Inductively Coupled Plazma(ICP) or an Atomic Absorption Spectrometer(AAS), and those of anions (C $l^{[-10]}$ , N $O_{3}$$^{[-10]}$ , S $O_{4}$$^{2-}$) were analayzed by the capillary electrophoresis method. The $Ca^{2+}$, S $O_{4}$$^{2-}$ and N $O_{3}$$^{[-10]}$ concentrations in spring were higher than those in other seasons. The lowest concentrations of these elements were found in summer, largely due to scavenging by frequent rains. Especially the $Ca^{2+}$ concentration on April was three to four times higher than the annual mean concentration. The enrichment factor(E.F.) of each element was calculated. The annual mean E.F. values of the $Ca^{2+}$, $Mg^{2+}$ and C $l^{[-10]}$ in 1992 were the same as those in 1993 except $k^{+}$ and S $O_{4}$$^{2-}$. The correlation formula between all cations and anions for the whole period was Anions = 0.759 * Cations + 0.066.Cations + 0.066.

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An Analysis of the Relationship between Climacteric Symptoms and Management of Menopause in Middle-aged Women (일 지역 중년여성의 폐경증상과 폐경관리와의 관계에 대한 연구)

  • Song, Ae-Ri
    • The Journal of Korean Academic Society of Nursing Education
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    • v.7 no.2
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    • pp.308-322
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    • 2001
  • The purpose of this study was to investigate the relationship between climacteric symptoms and management of menopause of middle -aged women. The subjects of this study were 261 women(40 to 60 years old). Data were collected from Jun. 1 to Jul. 15, 2001 by a structured questionnaire. The instruments employed were : 1) The Climacteric Symptoms Scale developed by Aeri Song and Eun soon Chung(1998). 2) The Management of Menopause Scale developed by Aeri Song(1997). The data were analyzed by the SPSS p.c. program using t-test, ANOVA and Pearson correlation coefficient. The results of the study were as follows : 1. Mean score of climacteric symptoms was $2.18{\pm}0.39$(Maximum 4, Minimum 1). The mean scores among the categories of climacteric symptoms, in descending order, were : a) physical and physiological reactions ($2.62{\pm}0.53$), b) social and family relationships ($2.23{\pm}0.50$), c) psychiatric and psychological reactions ($2.08{\pm}0.49$), d) relationship with sexual partner($1.73{\pm}0.54$), e) genitourinary reactions ($1.72{\pm}0.55$). 2. Mean score of management of menopause was $1.79{\pm}0.45$ (Maximum 4, Minimum 1). The mean scores among the categories of management of menopause, in descending order, were : a) dietary management($2.57{\pm}0.52$), b) self control ($2.24{\pm}0.57$), c) management of exercise and physical activity($2.14{\pm}0.75$), d) management of sex life($1.71{\pm}0.47$), e) management of professional health maintenance($1.61{\pm}0.59$). 3. There were statistically significant differences in the score of middle-aged women's self reported climacteric symptoms according to : a) occupation (t=-2.79, p<0.001) b) marriage state (t=-2.29, p<0.05) c) age of menarche (F=4.66, p<0.001) d) method of Sanhujori (post natal care & treatment) (F=4.22, p<0.001) e) hormone replacement therapy (t=-3.09, p<0.05). From the above statistics, several significant findings were noted : a) There were more climacteric symptoms from those who were unemployed, those who had no partner or were divorced and those who started a menarche earlier. b) There were less climacteric symptoms reported from those on hormone replacement therapy and those who followed their parents or parents-in-law advice regarding Sanhujori (postnatal care) 4. There were statistically significant differences in the score of middle-aged women's self reported management of menopause according to : The educational background (F=7.63, p<0.001), religion (F=3.74, p<0.001), income (F=3.65, p<0.001), number of parity (F=4.87, p<0.001), method of Sanhujori(postnatal care) (F=5.73, p<0.001), period of Sanhujori (postnatal care) (F=2.81, p<0.05), hormone replacement therapy (t=3.81, p<0.001). Women with higher educational background, strong religion, higher income, large number of parity, managed their post natal care well, were on HRT, managed their menopause significantly better than the others who took part in the survey. 5. It will be noted from the above that women's degree of climacteric symptoms showed a negative correlation to the management of menopause(r=-0.2146, p<0.001). The findings shown above suggest the need to develop a variable management of menopause, in order to improve climacteric symptoms of middle-aged women. It is hoped that the above findings will stimulate more detailed research into this matter, and thereby enable guidance to be given to women going through the menopause to cope with it in a less stressful way.

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The Classification Algorithm of Users' Emotion Using Brain-Wave (뇌파를 활용한 사용자의 감정 분류 알고리즘)

  • Lee, Hyun-Ju;Shin, Dong-Il;Shin, Dong-Kyoo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.2
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    • pp.122-129
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    • 2014
  • In this study, emotion-classification gathered from users was performed, classification-experiments were then conducted using SVM(Support Vector Machine) and K-means algorithm. Total 15 numbers of channels; CP6, Cz, FC2, T7. PO4, AF3, CP1, CP2, C3, F3, FC6, C4, Oz, T8 and F8 among 32 members of the channels measured were adapted in Brain signals which indicated obvious the classification of emotions in previous researches. To extract emotion, watching DVD and IAPS(International Affective Picture System) which is a way to stimulate with photos were applied and SAM(Self-Assessment Manikin) was used in emotion-classification to users' emotional conditions. The collected users' Brain-wave signals gathered had been pre-processing using FIR filter and artifacts(eye-blink) were then deleted by ICA(independence component Analysis) using. The data pre-processing were conveyed into frequency analysis for feature extraction through FFT. At last, the experiment was conducted suing classification algorithm; Although, K-means extracted 70% of results, SVM showed better accuracy which extracted 71.85% of results. Then, the results of previous researches adapted SVM were comparatively analyzed.

Thermally Stimulated Exoelectron Emission from LiF(Mg,Cu,Na,Si) Phosphor (LiF(Mg,Cu,Na,Si)형광체의 열자극엑소전자방출)

  • Doh, Sih-Hong;Jeong, Jung-Hyun;Aoki, M.;Nishikawa, T.;Tamagawa, Y.;Isobe, M.
    • Journal of Sensor Science and Technology
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    • v.3 no.2
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    • pp.11-15
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    • 1994
  • The TSEE characteristics of LiF(Mg,Cu,Na,Si)phosphor for gamma and beta rays are described. The TSEE glow curve of this phosphor showed 5 peaks in the range from $20^{\circ}C$ to $400^{\circ}C$ and its main peak appeared at $240^{\circ}C$. The sensitivity of the phospor for $^{60}Co$ gamma rays was about 450counts/mR. TSEE energy dependence for various beta radiation was nearly constant (${\pm}10%$) in the mean beta particle energy range from 0.02MeV to 0.8MeV. The efficiency of TSEE of the phosphor for beta radiation was $(2{\sim}15){\times}10^{-3}$.

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The Size of Calcaneus in Koreans (한국인의 종골 크기)

  • Kim, Jin-Su;Cho, Hun-Ki;Hwang, Sae-Min;Lee, Keun-Woo;Young, Ki-Won;Lee, Kyung-Tai
    • Journal of Korean Foot and Ankle Society
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    • v.17 no.2
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    • pp.143-149
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    • 2013
  • Purpose: Open reduction and internal fixation of calcaneal fracture using plate has been used. While numerous plates have been manufactured, most of the conventional plates are designed for westerners, realistically the size is larger for Korean. The domestic products, on the other hand, often have the undesirable screw holes and path. Therefore, we measured the radiologic parameter of Korean calcaneus for providing the plate and screw hole placements. Materials and Methods: We measured the outer lines and angles with over the 20 years old 291 females and 322 males. A: Length of inferior plane of calcaneus, B: Length of anterior plane of calcaneus, C: Length from line A to sinus tarsi, D: Length from line A to posterior point of posterior facet, E: Length from line A to calcaneal tuberosity, F: Length of posterior facet, G: Length from anterior point of line A to C, H: Length from line C to line D, a: Angle between A and B, b: Gissane angle, c: Bohler angle, d: Calcaneal pitch angle using Marosis m-view$^{(R)}$. Results: Mean A, B, C, D, E, F, G, H were 63.6, 26.4, 23.2, 43.7, 40.5, 26.9, 12.8, 18.1 mm. Mean a, b, c, d angle were 105.8, 122.4, 32.4, $20.5^{\circ}$. Male's calcaneus is significantly bigger than female's (p<0.001). Conclusion: AP calcaneus length 63.6 mm, maximal height 43.7 mm is considered to be helpful in making the Korean calcaneal plate.

Leading Edge Statistics of a Turbulent Premixed Flame (난류 예혼합 화염 선단부의 통계적 특성에 관한 수치적 연구)

  • Kwon, Jaesung;Huh, Kang Y.
    • Journal of the Korean Society of Combustion
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    • v.18 no.1
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    • pp.13-20
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    • 2013
  • Leading edge statistics are obtained by direct numerical simulation(DNS) of freely propagating incompressible and stagnating compressible turbulent premixed flames. Conditional averages of velocities in terms of reaction progress variable, c, and local flame surface density, ${\sum}^{\prime}_f$, are defined and compared through the flame brush. It holds asymptotically that $<u>_f=<S_d>_f$ and $<u>_u-<u>_b=D_t/L_w$ with the characteristic length scale of $\bar{c}$ variation, $L_w$. It also holds that $<u>_b=<u>_f$ for a freely propagating flame under no mean strain rate. The turbulent burning velocity, $S_T$, is determined by the conditional statistics at the leading edge under large activation energy.

A Comparison of Death Orientation in Student Nurses before and after Studying a Major (일 간호대학생들의 전공학습 전과 후 죽음에 대한 성향비교)

  • Choi Soon-Hee;Lee Eun-Ju;Park Min-Jung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.9 no.3
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    • pp.424-433
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    • 2002
  • This study was done to compare death orientation scores for student nurses before and after studying a major. The participants were 130 student nurses before the major and 123 student nurses after the major at C university in Kwang Ju city. The data were gathered from March, 1998 to September, 2001 using a questionnaire. The data were analysed by Chi square test, t-test, ANOVA and Pearson correlation coefficients. The results of this study are summarized as follows ; 1 The mean scores for death orientation before and after the major were 57.8 and 60.2 respectively. The mean score of death orientation after the major tended to be higher than before but they were not significantly different. 2. There were significant differences in death orientation scores between the two groups before the major for 'physical function (F=3.83, p=.023)' and 'attending a lecture on spiritual nursing (F=2.58, p=.010)'. After the major there were significant difference for 'feeling of health (F=4.76, p= .001)'. 3. The death orientation scores before the major showed an inverse correlation with religiosity score (r=-.239, p=.006). After the major there was no correlation with religion.

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