• 척추신경추나의학회지
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• 제5권2호
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• pp.103-111
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• 2010

ALS를 진단받았으며 2010.5.11부터 2010.6.10까지 ${\bigcirc}{\bigcirc}$한방병원에 입원한 요통을 호소하는 남환에 대하여 화침치료, 전침치료, 침치료, 구치료, 약물치료, 이학요법 등을 시행한 결과 K-ODI, VAS, K-ALSFRS-R 등의 평가 항목에 대하여 호전 경향을 보였다. ALS는 기본적으로 진행성 경과를 밟는 질환이기 때문에, 병의 진행을 늦추는 것과 대증치료를 통해 삶의 질을 높이는 것이 중심이 된다고 볼 수 있다. 본 환자의 경우 상기 한의학적 처치에 의해 일정한 효과가 나타났다. ALS에서 수반되는 요통의 호전에 의해 기능수행능력이 향상된 결과라고 볼 수 있다. 이는 한의학적 치료 방법이 ALS 환자의 치료에 있어서 통증을 감소시키고 일상생활에서의 기능수행능력을 향상시킴으로써 삶의 질을 높이는 대중치료의 역할을 수행할 수 있다는 단서라고 할 수 있다. 치료효과의 검증을 위해서는 추후 지속적인 증례 연구가 필요할 것으로 사료된다.

• Clinical and Experimental Pediatrics
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• 제59권7호
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• pp.298-302
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• 2016

Purpose: Recent reports showed that plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) could be a useful biomarker of intravenous immunoglobulin (IVIG) unresponsiveness and coronary artery lesion (CAL) development in Kawasaki disease (KD). The levels of these peptides are critically influenced by age; hence, the normal range and upper limits for infants and children are different. We performed an age-adjusted analysis of plasma NT-proBNP level to validate its clinical use in the diagnosis of KD. Methods: The data of 131 patients with KD were retrospectively analyzed. The patients were divided into 2 groups-group I (high NT-proBNP group) and group II (normal NT-proBNP group)-comprising patients with NT-proBNP concentrations higher and lower than the 95th percentile of the reference value, respectively. We compared the laboratory data, responsiveness to IVIG, and the risk of CAL in both groups. Results: Group I showed significantly higher white blood cell count, absolute neutrophil count, C-reactive protein level, aspartate aminotransferase level, and troponin-I level than group II (P<0.05). The risk of CAL was also significantly higher in group I (odds ratio, 5.78; P=0.012). IVIG unresponsiveness in group I was three times that in group II (odds ratio, 3.35; P= 0.005). Conclusion: Age-adjusted analysis of plasma NT-proBNP level could be helpful in predicting IVIG unresponsiveness and risk of CAL development in patients with KD.

• 한국식품위생안전성학회지
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• 제16권3호
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• pp.178-187
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• 2001

국내에서 널리 사용되고 있는 소르빈산 및 그 염류의 연령-성별에 따른 평균 소비자 및 극단 소비자의 섭취실태를 평가하고자 “1998년도 국민건강·영양조사”의 만 3세이상의 일인당 일일 식품 섭취량과 소르빈산의 실제 농도분석 치를 이용하여 일일 추정 섭취량을 구하였다. 조사된 소르빈산 및 그 염류의 일일 평균 추정 섭취량은 소르빈산으로서 0.09-5.1 mg/kg bw/day, 극단추정 섭취량은 3.42-14.65mg1kg bw/da)이었으며 일일섭취허용량(ADI)에 대한 비율은 평균 소비자의 경우 0.4-2.1%,극단 섭취자의 경우 13.7-58.6%로 나타났다. 소르빈산 섭취에 기여하는 식품은 식육가공품, 절임류, 어육가공품으로 나타났고, 소르빈산의 추정 섭취량은 극단 및 평균 소비자에 대해 연령에 반비례하는 경향이었으나 성별에 의한 차이는 나타나지 않았다. 그러므로 국내 소르빈산 섭취량은 극단 소비자를 포함한 3세 이상의 모든 인구아군에서 ADI보다 낮은 것으로 나타났다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권2호
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• pp.154-162
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• 2020

Purpose: The Cow's Milk-related Symptom Score (CoMiSS^TM), which considers crying, regurgitation, stools, skin and respiratory symptoms, was developed as an awareness tool for evaluating cow's milk-related symptoms. The scoring ranges from 0 to 33. A score ≥12 was proposed as being likely cow's milk-related and suggestive of allergy to cow's milk. This study aimed to determine the age-related CoMiSS^TM values in presumed healthy infants in Poland. Methods: This was a cross-sectional study conducted in well-child clinics in two locations. Parents of the presumed healthy infants aged ≤6 months were approached during a routine checkup/vaccination visit. The exclusion criteria were as follows: presence of acute or chronic diseases, preterm delivery, treatment with therapeutic formula, and use of any food supplements (except vitamins) or medications. Results: Data from 226 infants were obtained (median age [Q1-Q3], 4 months [3-4]). The overall median (Q1-Q3) and mean (standard deviation) CoMiSS^TM values were 4 (2-7) and 4.7 (3.5), respectively. The 95th percentile was 11. Scores on some, albeit not all, components of the CoMiSS^TM significantly differed between age groups (crying, stools) or feeding type groups (stools and skin symptoms). Eleven children (4.9%) scored ≥12. Conclusion: This study adds to earlier age-related CoMiSS^TM data by providing CoMiSS^TM values in presumed healthy infants in Poland.

• Journal of Nutrition and Health
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• 제39권7호
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• pp.692-698
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• 2006

The voluntary addition of vitamins and minerals to the appropriate foods may help reduce the risks associated with low intakes of these micronutrients, yet the potential of excessive intake, particularly for persons consuming very large amount of foods needs to be addressed. Using the Flynn's model to estimate the level of each vitamins and minerals that can be added safely to foods, maximum levels of fortification to conventional foods per 100 kcal portion were estimated. Critical factors in the Flynn's model included tolerable upper intake level (UL), each micronutrient intake at the $95^{th}$ percentile, the proportion of fortified foods in the diets of individuals, the proportion of foods to which micronutrients could be practically added, and a range of estimates for fractions of foods which might be actually fortified in each nutrient. Food vehicles included all foods except for fresh foods and alcoholic beverages, in general. With fortification of 50% of all potentially fortifiable foods, micrornutrients could be added safely to foods at levels per 100 kcal 1) > 100% Recommended Intake (RI) for vitamin $B_12$, 2) 1,200% RI for vitamin $B_1$ and niacin, 3) 1,000% $B_1$ for vitamins $B_2$ and $B_6$, 4) 400% RI for vitamin E, 5) 30% RI for calcium, 6) 20% RI for folic acid, iron and zinc, 7) 10% RI for manganese, 8) no fortification for magnesium, phosphorous and vitamin A, and 8) further consideration of vitamin D, copper and selenium due to insufficient evidence. Results of this study suggests a wide range of vitamins and minerals that can be added safely to foods in current diets of Koreans.

• 한국수산과학회지
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• 제41권3호
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• pp.155-162
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• 2008

The seawater in the Taean area was surveyed to evaluate the conditions of the bay and compliance with the bacteriological criteria for a designated area for shellfish production for export. Samples of seawater were collected monthly at 34 sampling stations established in the survey area from January 2002 to December 2004. The bacterial density in the coastal area close to a pollution source located to the northeast of the survey area was higher than in the open sea to the west. The bacteriological counts in the water did not change with 16.5mm of rainfall, but increased abruptly after 65.4mm of rainfall. The total coliform and fecal coliform most probable numbers (MPNs) of 1,224 seawater samples in the survey area were <1.8-2,400 and <1.8-790 MPN/100 mL, respectively. The geometric mean and estimated 90th percentile of total coliforms were 1.9-3.4 and 2.7-26.3 MPN/100mL, respectively, and for fecal coliforms were <1.8-2.6 and 1.8-12.0 MPN/100mL, respectively. The bacteriological water quality in the Taean seawater area met the National Shellfish Sanitation Program criteria for an approved area and the Korea Shellfish Sanitation Program criteria for a designated area for shellfish production for export.

• 대한방사선기술학회지:방사선기술과학
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• 제22권2호
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• pp.41-46
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• 1999

Osteoporosis, which causes mainly fracture of the spine, proximal femur and distal radius by minimal trauma, is a major public health problem and its prevalence is steadily increasing in Korea according to the development of public health care. There are reliable methods for diagnosis based on bone densitometry. Early detection and intervention are important for reducing the incidence of fractures. A consensus definition of osteoporosis, based on bone density measurement, has been developed by the World Health Organization(WHO). In this study, bone mineral density(RMD) was measured by dual energy x-ray absorptiometry(DEXA) at the proximal femur and lumbar spine in 132 post-menopausal women. The purpose of this study is to find influential factors on the BMD of the proximal femur and the lumbar spine and to analyze correlation between BMD and the problematic factors. We obtained the following results : 1. Mean BMD score, T-score and Z-score of the proximal femur were $0.81(g/cm^2)$, -2.45(S.D.) and -2.09(S.D.) respectively and in the lumbar spine were $0.83(g/cm^2)$, -2.02(S.D.), -2.43(S.D.) respectively. 2. In correlation analysis between BMD and many factors, correlation coefficients were -0.467, 0.212, -0.321 and 0.241 in age, height, duration after menopause respectively. BMI and the residuals were comparatively small. 3. Correlation coefficients to age matched BMD, in height and body weight were 0.222 and 0.241, in age and duration after menopause were -0.268, -0.282. 4. The fracture threshold of proximal femur BMD to the 90th percentile was $0.845(g/cm^2)$. 5. At the result of multiple regression analysis, age, body weight, $BMI(kg/m^2)$ and duration after menopause described as significant variables.

• 한국학교보건학회지
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• 제18권2호
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• pp.73-84
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• 2005

Purpose : This study was designed to apply a "stage of change" exercise intervention program to obese children in elementary school and to examine its effects on their BMI. stage of change. process . and self-efficacy in exercise. Methods : The experimental group included 64 children in the fourth . fifth and sixth grades. from one elementary school. whose BMI was in the H5th percentile or more for their age groups. The control group had 6 1 students from a different one elementary school whose conditions were the same as those of the experimental group. Results: After the stage of change exercise intervention was applied, the BMI of the experimental group decreased by a significant enough degree to conclude that the program was effective in decreasing BMI. After the application of the program. the experimental group experienced a significant increase in their helping relationships. counter-conditioning . reinforcement management and stimulus control compared 10 the control group. After the program. self-efficacy in terms of exercise increased significantly in the experimental group. Conclusion: A stages of change exercise intervention program has been shown to engage individual students and encourage them 10 maintain a higher fitness level that promote s self-efficacy in exercise and therefore moves them towards healthier lifestyles. Moreover. the study proved that a significant reduction of BMI was achieved by the stages of change exercise intervention program.

• 가정과삶의질연구
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• 제26권5호
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• pp.1-14
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• 2008

The purpose of this study was to examine factors contributing to financial resources interchange type and amount of the middle aged and the elderly household. For this study, the 6th KLIPS data was used, and sample size was 1,679 households including those with head of household being over the age of 50. Statistical analysis was conducted to examine frequency, percentile, mean and standard deviation, Pearson's correlation, Anova, Duncan's multiple range test and Heckman analysis First, Interchange amount of Benefits type household was significantly different according to the householder's gender, existence or nonexistence of a spouse, age, educational background, home ownership, family type and place of residence. However, interchange amount of provide- type households were significantly different according tohouseholder's gender, existence or nonexistence of a spouse, educational background, whether retired or not, and home ownership. Second, The receptive type of households and net receptive expense of households in terms of the financial resources interchanges and the findings of Heckman analyses suggest that the variables to have a significant effect on the receptive types of financial interchanges were as gender, age, education level, retired or not, and current economics. Factors having an effects on net receptive expense were age, and family type and for the number of receptive of financial resources, whether there is the receptive of financial resources, total income, total asset. Third, The supplying type of households and net supplying expense of households in terms of the financial resources interchanges, whether or not the type of financially supplying households is significant were residential area, total income, house ownership. Factor having an effect net supplying expense were age, family type, whether there is the supplying of financial resources, family satisfaction, and house ownership.

• 한국환경보건학회지
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• 제32권2호
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• pp.186-191
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• 2006

Metal contamination of medicinal herbs is of growing concern because of their potential adverse health effects. In this study, metal exposures were estimated and their potential health risks were preliminarily evaluated using available data including metal contamination levels and consumption estimates of herbal medicine in Korea. Consumption and contamination data of 34 medicinal herbs abundantly used in Oriental medicine in Korea were used in this study. Lead, mercury, arsenic, cadmium, cobalt, and chrome were identified as contaminants of potential health concerns. Even based on a conservative exposure scenario, i.e., consuming 5 times more herbal medicine with 95th percentile contamination levels, health risks associated with herbal medicine consumption were estimated to be minuscule. Herbal consumption was 0.3% of the provisional tolerable daily intake levels recommended by Joint Expert Committee on Food Additives (JECFA) of WHO/FAO. However, it should be noted that there are several important assumptions and uncertainties associated with this evaluation: This study was conducted for only 34 types of medicinal herbs of which consumption and metal contamination data were available. In addition, there are no reliable herbal medicine consumption data among Korean population. The pattern and amount of herbal (medicine) consumption in Korea need to be investigated in order to conduct more refined risk assessment associated with metal contamination in medicinal herbs.