• Journal of the Korean Data and Information Science Society
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• v.28 no.4
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• pp.743-754
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• 2017

Assessing bioequivalence between original drug and generic drug is traditionally based on $2{\times}2$ crossover design. As bioequivalence trials for highly variable drugs are getting popular, the required sample size based on $2{\times}2$ crossover design would be very large, which might cause the ethical concerns. Regulatory agencies like EMA and MFDS recommended higher order crossover designs such as $2{\times}4$, $4{\times}2$ and $4{\times}4$ crossover designs. Alternatively, a $2{\times}3$ dual design may be recommended in terms of economical and ethical points of view in comparison with the $2{\times}4$ crossover design for highly variable drug. In this study, we consider some statistical characteristics of $2{\times}3$ dual design and propose statistical procedures for calculating sample size and assessing bioequivalence based on $2{\times}3$ dual design. We also discuss the proposed procedures from the perspective of newly revised bioequivalence guidance issued by MFDS.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.7
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• pp.633-640
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• 2002

In this paper, the small chip meander antenna for dual-frequency operation is presented. The proposed chip meander antennas was fabricated by the ceramic chip using LTCC-MLC process. It is a novel compact dual-frequency design using a meandered patch that achieves more degrees of freedom for adjusting dual-frequency operation and the size reduction with narrow frequency ratio. And it is proposed that the 3D structure for additional size reduction of the meander antenna. The size reduction of the 3D meander antenna is as large as 50 % as compared to the design for dual-frequency operation not using 3D structure. It is observed that the principle of dual-frequency operation through current distribution, return loss and radiation pattern.

• Current Optics and Photonics
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• v.2 no.3
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• pp.241-249
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• 2018

We report a midinfrared dual-field-of-view (FOV) optical system design for an airborne electro-optical targeting system. To achieve miniaturization and weight reduction of the system, it has a common aperture and fore-optics for three different spectral wavelength bands: an electro-optic (EO) band ($0.6{\sim}0.9{\mu}m$), a midinfrared (IR) band ($3.6{\sim}4.9{\mu}m$), and a designation laser wavelength ($1.064{\mu}m$). It is free to steer the line of sight by rotating the pitch and roll axes. Our design co-aligns the roll axis, and the line of sight therefore has a fixed entrance pupil position for all optical paths, unlike previously reported dual-FOV designs, which dispenses with image coregistration that is otherwise required. The fore-optics is essentially an achromatized, collimated beam reducer for all bands. Following the fore-optics, the bands are split into the dual-FOV IR path and the EO/laser path by a beam splitter. The subsequent dual-FOV IR path design consists of a zoom lens group and a relay lens group. The IR path with the fore-optics provides two stepwise FOVs ($1.50^{\circ}{\times}1.20^{\circ}$ to $5.40^{\circ}{\times}4.32^{\circ}$), due to the insertion of two Si lenses into the zoom lens group. The IR optical system is designed in such a way that the location and f-number (f/5.3) of the cold stop internally provided by the IR detector are maintained when changing the zoom. The design also satisfies several important performance requirements, including an on-axis modulation transfer function (MTF) that exceeds 10% at the Nyquist frequency of the IR detector pitch, with distortion of less than 2%.

• The Journal of the Korea institute of electronic communication sciences
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• v.12 no.6
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• pp.1049-1056
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• 2017

In this paper, a microstrip-fed dual-band monopole antenna with two arc-shaped lines for WLAN(: Wireless Local Area Networks) applications was designed, fabricated and measured. The proposed antenna is based on a microstrip-fed structure, and composed of two arc-shaped lines and then designed in order to get dual band characteristics. We used the simulator, Ansoft's High Frequency Structure Simulator(: HFSS) and carried out simulation about parameters L2, L5, and with/without slit to get the optimized parameters. The proposed antenna is made of $13.0{\times}34.0{\times}1.0 mm^3$ and is fabricated on the permittivity 4.4 FR-4 substrate($12.0{\times}34.0{\times}1.0mm^3$). The experiment results are shown that the proposed antenna obtained the -10 dB impedance bandwidth 360 MHz (2.29~2.65 GHz) and 1,245 MHz (4.705~5.95 GHz) covering the WLAN bands. Also, the measured gain and radiation patterns characteristics of the proposed antenna are presented at required dual-band(2.4 GHz band/5.0 GHz band), respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.2
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• pp.152-163
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• 2010

In this paper, a cavity-backed high gain dual band microstrip antenna with Frequency Selective Surface space(FSS) for WLAN is proposed. The proposed antenna that operates in IEEE 802.11a/b bands with similar radiation pattern and gain is fabricated on RO4003 substrate with a dielectric constant of 3.38. The size of the antenna is $71.5{\times}42.0{\times}6.6\;mm^3$, and the FSS size is $120.0{\times}120.02\;mm^3$. The ground plane size including cavity is $150.0{\times}145.0\;mm^3$. The antenna is fed by coaxial cable. The simulated bandwidths of the antenna are 2.369~2.517 GHz and 5.608~5.833 GHz for VSWR<2. The gains are 11.23 dBi and 12.60 dBi, respectively, for the lower and upper bands.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.9
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• pp.841-848
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• 2016

In this paper, a microstrip-fed dual-band monopole antenna with DGS(: Defected Ground System) for WLAN(: Wireless Local Area Networks) applications was designed, fabricated and measured. The proposed antenna is based on a microstrip-fed structure, and composed of two strip lines and DGS structure and then designed in order to get dual band characteristics. We used the simulator, Ansoft's High Frequency Structure Simulator(: HFSS) and carried out simulation about parameters W2, L10, W3, and DGS to get the optimized parameters. The proposed antenna is made of $21.0{\times}36.0{\times}1.6mm3$ and is fabricated on the permittivity 4.4 FR-4 substrate. The experiment results are shown that the proposed antenna obtained the -10 dB impedance bandwidth 700 MHz(2.10~2.80 GHz) and 1,780 MHz(5.02~6.80 GHz) covering the WLAN bands. Also, the measured gain and radiation patterns characteristics of the proposed antenna are presented at required dual-band(2.4GHz band/5.0GHz band), respectively.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.11A
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• pp.912-920
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• 2003

This paper is about the design of a small wide-band slot loop antenna, which consists of dual offset-fed and rectangular loop within the slot on a substrate. The proposed antenna is a novel structure generating a multi-resonances due to three geometrical resonance structures. The impedance matching of this antenna can be accomplished by changing the offset position of dual-fed at resonance frequencies. In this experiment, the slot of a fabricated antenna has a center frequency of 6.755㎓, 12.5mm${\times}$50mm in size and the rectangular loop has 10.5mm${\times}$27.5mm in size. The measured result is fractional bandwidth 63.21% with VSWR 2:1, which is agreed with the simulated result within 5% of error, and the maximum antenna gain is 7.42㏈i.

• Journal of IKEEE
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• v.17 no.3
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• pp.267-274
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• 2013

This paper presents a design of LLC resonant converter IC for LED backlight unit based on PFM/PWM dual-mode feedback. Dual output LLC resonant architecture with a single inductor is proposed, where the master output is controlled by the PFM and slave output is controlled by the PWM. To regulate the master output PFM is used as feedback to control the frequency of the power switch. On the other hand, PWM feedback is used to control the pulse width of the power switch and to regulate the slave output. This chip is fabricated in 0.35um 2P3M BC(Bipolar-CMOS-DMOS) Process and the die area is $2.3mm{\times}2.2mm$. Current consumptions is 26mA from 5V supply.

• 한국정보통신설비학회:학술대회논문집
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• 2008.08a
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• pp.3-6
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• 2008

In this paper, we propose the folded PIFA with its made an alteration to a factor of resonance for L-slot PIFA. Proposed antenna maintain diminished size patch and improve each bandwidth of GSM(0.88$\sim$-0.96 GHz) and W-CDMA(1.92$\sim$2,17 GHz) for miniaturized repeater. The non-slot step folded PIFA's structure that design of essence was general L-slot PIFA for dual-band. It has no U-slot, multi band and the another slot. The parameters of proposed antenna were optimized for dual-band and compact size by folded singleness patch. Proposed antenna by using folded singleness patch take satisfaction main point, bandwidth of GSM and W-CDMA, compact patch size($39{\times}21{\times}13mm^3$). The antenna was designed by FDTD simulation tool and it was made from result of simulation. Measured data shown that the proposed non-slot step folded PIFA was strong possibility.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.2
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• pp.75-79
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• 2015

In this paper, a dual band antenna with the operating frequency in HF and UHF band was proposed. The antenna structure consists of three spiral turns coil in the bottom side to generate the HF frequency of 13.56 MHz. In the top of the antenna, an inverted-spiral dipole structure is used to create the UHF frequency of 922 MHz. The dual band antenna was optimized to reduce size with $80mm{\times}40mm{\times}0.8mm$ dimension. The antenna presents the omnidirectional characteristic with high gain. To validate the theoretical design, the antenna was simulated using FR-4 substrate and verified the simulation results.