• Title/Summary/Keyword: ${gamma}K$

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Molecular Cloning and mRNA Expression of the Bovine Peroxisome Proliperator Receptor Gamma(PPARγ) (한우 PPARγ 유전자의 동정과 mRNA의 발현)

  • Jeoung, Y.H.;Lee, S.M.;Park, H.Y.;Yoon, D.H.;Choi, J.G.;Moon, S.J.;Kang, M.J.
    • Journal of Animal Science and Technology
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    • v.46 no.1
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    • pp.23-30
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    • 2004
  • The peroxisome proliferator-activated receptor $\gamma$(PPAR$\gamma$), a member of the steroid/thyroid nuclear hormone receptor suferfamily of ligand-activated transcription factor, is an important regulator of adipocyte gene expression and differentiation. In this studies, we report the identification, characterization, and expression of a Hanwoo PPAR$\gamma$ gene. The PPAR$\gamma$ cDNA sequence of the Hanwoo show strong conservation with the corresponding sequences reported in other species except of three amino acid sequences. The distribution of PPAR$\gamma$ mRNA in various tissues of Korean cattle aged 12 months were investigated using Northern Blot analysis. The highest expression was detected in adipose tissue, more lower expression was detected in colon, small intestine, kidney, lung, while expression was not detected in brain, heart. PPAR$\gamma$ expression was higher in adipose tissue of Korean cattle when aged 30 months than aged 12 months. These results indicated PPAR$\gamma$, regulator adipocyte gene expression and differentiation, related on adipose differentiation in Korean native cattle(HANWOO).

Effects of Surface Characterization of γAl2O3 Particles by Aging in the Sol Preparation (졸 합성시 숙성이 γAl2O3 입자의 표면특성에 미치는 영향)

  • Yoo, Seung-Joon;Kwak, Dong-Heui;Kim, Hyeong-Gi;Hwang, Un-Yeon;Park, Hyung-Sang;Yoon, Ho-Sung;Jang, Hee Dong
    • Korean Chemical Engineering Research
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    • v.46 no.3
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    • pp.545-549
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    • 2008
  • The surface characteristics of calcined ${\gamma}-Al_2O_3$ particles as well as ${\gamma}-AlO$(OH) sol particles were controlled by aging in the boehmite sol preparation. As a result of the study, the IEPs of ${\gamma}-AlO$(OH) particles were decreased from pH 9.25 to pH 8.70 and those of the calcined ${\gamma}-Al_2O_3$ particles were decreased from pH 9.90 to pH 8.86 by the increase of the aging times. As a result of the acidic and basic characterization of the calcined ${\gamma}-Al_2O_3$ particles by the aging, the amount of acid sites was decreased from 0.1367 mmol/g to 0.0783 mmol/g by the increase of the aging times and Hammett acidity, $H_o$ was showed the acidic strength of 4.8 or above. On the other hand, the amount of basic sites was decreased from 0.4399 mmol/g to 0.3074 mmol/g by the increase of the aging times. Based on these results, we proposed the fact that the aging step in the sol-gel process was an important step to control the surface characterization of ${\gamma}-Al_2O_3$ particles including acidity and basicity.

Analysis of External Gamma Exposure

  • Han, Moon-Hee;Hwang, Won-Tae;Kim, Eun-Han;Suh, Kyung-Suk;Park, Young-Gil
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.05b
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    • pp.566-570
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    • 1997
  • The effect of average gamma energy on the external radiation dose has been analyzed. Cloud- and groundshine have been calculated according to the average gamma energy. Monte Carlo integration method was used for the calculation of cloudshine and Romberg quadrature method was adopted for groundshine. The analysis shows that the external gamma exposure is strong]y dependent on the gamma energy and the distribution of radiation sources.

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Interfacial Characteristics of Epoxy Composites Filled with γ-APS Treated Natural Zeolite (γ-APS로 표면처리된 천연 제올라이트/에폭시 복합재료의 계면특성)

  • Lee, Jae-Young;Lee, Sang-Keun;Kim, Sang-Wook
    • Journal of Adhesion and Interface
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    • v.2 no.3
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    • pp.1-8
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    • 2001
  • Epoxy composites filled with natural zeolite was prepared to investigate the effects of silane coupling agent, ${\gamma}$-APS (${\gamma}$-aminopropyltriethoxysilane)on the surface free energy, tensile properties and interfacial morphology. The value of Lifshitz-van der Waals component, ${\gamma}{\frac{LW}{SV}}$ for polar was $19.22mJ/m^2$ and increased, while that of Lewis acid-base component, ${\gamma}{\frac{AB}{SV}}$ for polar was $15.27mJ/m^2$ and decreased with the increasing content of ${\gamma}$-APS treatment. It is due that the surface of the zeolite is more coated by hydrophobic of alkyl group than hydrophilic amine or hydroxyl group. The tensile strength and Young's modulus of epoxy system were improved by the treatment with ${\gamma}$-APS due to the strong interface bonding, which was confirmed by SEM.

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GREEN'S ADDITIVE COMPLEMENT PROBLEM FOR k-TH POWERS

  • Ding, Yuchen;Wang, Li-Yuan
    • Journal of the Korean Mathematical Society
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    • v.59 no.2
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    • pp.299-309
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    • 2022
  • Let k ⩾ 2 be an integer, Sk = {1k, 2k, 3k, …} and B = {b1, b2, b3, …} be an additive complement of Sk, which means all sufficiently large integers can be written as the sum of an element of Sk and an element of B. In this paper we prove that $${{\lim}\;{\sup}}\limits_{n{\rightarrow}{\infty}}\;{\frac{{\Gamma}(2-{\frac{1}{k}})^{\frac{k}{k-1}}{\Gamma}(1+{\frac{1}{k}})^{\frac{k}{k-1}}n^{\frac{k}{k-1}}-b_n}{n}}\;{\geqslant}\;{\frac{k}{2(k-1)}}\;{\frac{{\Gamma}(2-{\frac{1}{k}})^2}{{\Gamma}(2-{\frac{2}{k}})}},$$ where 𝚪(·) is Euler's Gamma function.

Lack of Effects of Peroxisome Proliferator-Activated Receptor Gamma Genetic Polymorphisms on Breast Cancer Risk: a Case-Control Study and Pooled Analysis

  • Park, Boyoung;Shin, Aesun;Kim, Kyee-Zu;Lee, Yeon-Su;Hwang, Jung-Ah;Kim, Yeonju;Sung, Joohon;Yoo, Keun-Young;Lee, Eun-Sook
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9093-9099
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    • 2014
  • A growing body of evidence suggests that the peroxisome proliferator-activated receptor-gamma ($PPAR{\gamma}$) gene may harbor targets for the chemoprevention of breast cancer. However, it is unclear whether polymorphisms in the $PPAR{\gamma}$ gene are associated with the susceptibility of breast cancer. We performed a candidate gene association study between $PPAR{\gamma}$ polymorphisms and breast cancer and a meta-analysis on the association of breast cancer with selected $PPAR{\gamma}$ variants. Six single nucleotide polymorphisms (SNPs) in the $PPAR{\gamma}$ gene were analyzed among 456 breast cancer patients and 461 controls from the National Cancer Center in Korea. Association between the polymorphisms and breast cancer risk were assessed using the Cochrane-Armitage test for trend and a multivariate logistic regression model. Two SNPs, rs3856806 and rs1801282, had been previously analyzed, thus enabling us to perform pooled analyses on their associations with breast cancer susceptibility. Our findings from the candidate gene association study showed no association between the $PPAR{\gamma}$ gene polymorphisms and breast cancer risk. A meta-analysis combining existing studies and our current study also refuted an association of the $PPAR{\gamma}$ gene with breast cancer. Our findings suggest that the $PPAR{\gamma}$ gene may not harbor variants that alter breast cancer susceptibility, although a moderate sample size might have precluded a decisive conclusion.

Optimization of ${\gamma}-Polyglutamic$ Acid Production by Bacillus subtilis ZJU-7 Using a Surface-response Methodology

  • Shi, Feng;Xu, Zhinan;Cen, Peilin
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.3
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    • pp.251-257
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    • 2006
  • The components of the media used to elicit the biosynthesis of $poly-{\gamma}-glutamic$ acid $({\gamma}-PGA)$ by Bacillus subtilis ZJU-7 were investigated, particularly the carbon and nitrogen sources Of the 7 carbon sources investigated, sucrose induced the highest rate of ${\gamma}-PGA$ productivity; among the nitrogen sources, tryptone had the best effect for ${\gamma}-PGA$ production. A $2^{6-2}$ fractional factorial design was used to screen factors that influence ${\gamma}-PGA$ production significantly, and a central composite design was finally adopted to formulate the optimal medium. ${\gamma}-PGA$ productivity improved approximately 2-fold when the optimal medium was used compared with the original nonoptimized medium, and volumetric productivity reached a maximum of 58.2 g/L after a 24-h cultivation period.

Binding Model of Amentoflavone to Peroxisome Proliferator-Activated Receptor γ

  • Lee, Jee-Young;Kim, Jin-Kyoung;Lee, So-Jung;Lee, Eun-Jung;Shin, So-Young;Jin, Qinglong;Yoon, Do-Young;Woo, Eun-Rhan;Kim, Yang-Mee
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1475-1479
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    • 2012
  • Human peroxisome proliferator-activated receptor gamma ($hPPAR{\gamma}$) has been implicated in numerous pathologies, including obesity, diabetes, and cancer. In this study, we verified that amentoflavone is an agonist of $hPPAR{\gamma}$ and probed the molecular basis of its action. It was demonstrated that amentoflavone bound $hPPAR{\gamma}$ with high (picomolar) affinity and increased the binding between $hPPAR{\gamma}$ and steroid receptor coactivator-1 (SRC-1) by approximately 4-fold. Based on a docking study, for the first time, we propose a model of amentoflavone and $hPPAR{\gamma}$ binding in which amentoflavone forms three hydrogen bonds with the side chains of His323, Tyr327, and Arg280 in $hPPAR{\gamma}$ and participates in two hydrophobic interactions.

Fuzzy γ-Quasi Open Set and Fuzzy γ-Quasi Continuity

  • Min, Won-Keun
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.10 no.3
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    • pp.200-202
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    • 2010
  • In this paper, we introduce the concept of fuzzy ${\gamma}$-quasi open sets which are generalizations of fuzzy ${\gamma}$-open sets, and obtain some basic properties of such fuzzy sets. Also we introduce and study the concepts of fuzzy ${\gamma}$-quasi continuous mapping and fuzzy ${\gamma}$-quasi open(closed) mapping.

Effect of Low Dose ${\gamma}$ Radiation on the Dormancy and Growth of in vitro Microtuvers of Potato(Solanum Tuberosum L.) (저선량 ${\gamma}$선이 기냐 생산된 감자 소괴경의 휴면과 생에 미치는 효과)

  • Kim, Dong-Hee;Back, Myung-Hwa;Jeon, Jae-Heung;Kim, Jae-Sung
    • Korean Journal of Environmental Biology
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    • v.19 no.4
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    • pp.270-277
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    • 2001
  • To observe the stimulating effect of low dose ${\gamma}$ radiation on the dormancy breaking and growth, microtubers induced in vitro of two potato (Solanum tuberosum L. cv. Dejima and cv. Superior) cultivars with different storage duration were irradiated with ${\gamma}$ radiation at the dose of $0.5{\sim}30$ Gy. Sprouting rate, growth and tuber yield of ‘Dejima’ microtuber were increased by ${\gamma}$ radiation in the range of $2{\sim}16$ Gy. In the microtuber of ‘Superior’, the sprouting rate was promoted by 2 Gy and 4 Gy irradiation, and the growth and tuber yield by 0.5 Gy and 4 Gy irradiation. There were not that much difference in chlorophyll content of potato plantlet by the low dose ${\gamma}$ irradiation. These results suggested that low dose ${\gamma}$ radiation stimulated the dormancy breaking and potato growth.

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