• Neonatal Medicine
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• 제15권2호
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• pp.183-189
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• 2008

신생아의 선천성 거대 간내 혈관내피종을 복부 단층 촬영과 $^{99m}Tc$-RBC 간스캔을 통해 진단하고, 대증요법과 함께 IFN$\alpha$를 11개월간 단독으로 피하 투여하여 크기 감소를 유도한 후 남은 병변의 완전한 수술적 제거와 조직학적 확진을 시행하였음을 보고하는 바이다.

• Nuclear Medicine and Molecular Imaging
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• 제40권5호
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• pp.275-278
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• 2006

We report the case of a 73-year-old man who had prostate cancer with bone metastases. Tc-99m HDP Whole body bone scan revealed multiple areas of increased bony uptake consistent with widespread bone metastases. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) demonstrated mild F-18 FDG uptake in the lymph nodes of neck, abdomen, and pelvis. However, abnormal F-18 FDG uptake was not seen in the skeletal system. Biopsy and immunohistochemical stains of left supraclavicular mass showed metastatic prostate adenocarcinoma. Currently, there are a few reported cases of F-18 FDG PET/CT evaluation of bone metastases in prostate cancer. We discuss the discrepancy between F-18 FDG PET/CT and bone scan in the detection of osseous metastases of prostate cancer.

• 대한핵의학회지
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• 제38권2호
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• pp.175-179
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• 2004

Molecular nuclear cardiac imaging has included Tc-99m Annexin imaging to visualize myocardial apoptosis, but is now usually associated with gene therapy and cell-based therapy. Cardiac gene therapy was not successful so far but cardiac reporter gene imaging was made possible using HSV-TK (herpes simplex virus thymidine kinase) and F-18 FHBG (fluoro-hydroxymethylbutyl guanine) or I-124 FIAU (fluoro-deoxyiodo-arabino-furanosyluracil). Gene delivery was performed by needic injection with or without catheter guidance. Tk expression did not last longer than 2 weeks in myocardium. Cell-based therapy of ischemic heart or failing heart looks promising, but biodistribution and differentiation of transplanted cells are not known. Reporter genes can be transfected to the stem/progenitor cells and cells containing these genes can be transplanted to the recipients using catheter-based purging or injection. Repeated imaging should be available and if promoter are varied to let express reporter transgenes, cellular (trans)differentiation can be studied. NIS (sodium iodide symporter) or D2R receptor genes are promising in this aspect.

• 대한두경부종양학회지
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• 제12권2호
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• pp.235-240
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• 1996

갑상선 유두암에 의한 뇌전이는 극히 드물게 발견되어며 그 진단 및 치료방법의 설정이 아직 확립되어 있지 못한 상태이다. 저자들은 갑상선 유두암으로 5년전 갑상선 전절제술을 시술받고 갑상선 호르몬 복용을 하고 있던 24세의 남자에서 간헐적인 발작을 일으킨 전두골내 병소가 갑상선 유두암의 전이에 의한 것임을 조직학적으로 확인할 수 있었다. 이 병소는 전신 요오드 주사상에서는 나타나지 않았지만 Brain CT 및 MRI 소견으로만 병변의 진단이 가능하였으며 stereotactic cranitomy에 의한 종양제거로 비교적 만족스러운 결과를 얻어 현재 밀착추적중에 있다.

• 대한핵의학회지
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• 제19권1호
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• pp.145-148
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• 1985

A small number of pathologic entities such as Budd-Chiari Syndrome, cirrhosis, focal nodular hyperplasia, and superior and inferior vena cava obstruction has been reported to result in focal areas of increased uptake of radiocolloid on the hepatoscintigram. We recently studied a patient with focal accumulation of $^{99m}Tc-phytate$ at the inferior aspect of the liver, at the junction of the right and left lobe. The superior vena cava scintiangiogram was taken for the evaluation of the superior vena cava obstruction and collateral circulations. As a result of superior vena caval obstruction a considerable amount of blood flowed to the liver through the anterior parietal and periumblical venous channels. A certain fraction of radiocolloid delivered by the rete mirabile perfused to a localized area of the liver. This would explain the hot spot around the porta hepatis in this case.

• 대한핵의학회지
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• 제17권2호
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• pp.79-82
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• 1983

Traditionally, a positive bone scan shows single or multiple areas of increased uptake in the metastatic skeletal disease. The occurence of "cold" lytic-like or photon-deficient lesions in bone imaging is probably uncommon. Photon-deficient focus or cold lesion of the sternum was demonstrated on $^{99m}Tc-MDP$ bone imaging in 2 individuals with acute myloid leukemia and primary hepatoma, respectively.

• 대한핵의학회지
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• 제19권2호
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• pp.105-107
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• 1985

It is very difficult to check the severity and clinical course of the toxicity in snake bite patients by virtes of clinical manifestation and laboratory tests. And we observed the. findings of bone scan with 99mTc-MDP in two snake bite patients. First patient was bitten in the right ankle with local pain and swelling. The finding of bone scan of him was increased uptake of radionuclide in the soft tissue of right leg and thigh. Others were normal findings. Second patient was bitten in the right hand. But his symptom was severe and he complained local pain and swelling, nausea, blurred vision, and oliguria. The bone scan findings of second patient was; Increased uptake of radionuclide in the soft tissue of whole body. Decreased uptake in the bone tissue. Renal outline was not delineated. Follow up study 10 days after, revealed more improved findings in the scan.

• 대한핵의학회지
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• 제34권5호
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• pp.426-432
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• 2000

After surgical operation in patients with arteriovenous malformation (AVM), normal pressure perfusion breakthrough (NPPB) is one of the major complications. Brain perfusion SPECT with acetazolamide stress was known to be useful to evaluate the vascular reserve in several neurological and neurosurgical conditions. The authors performed acetazolamide brain perfusion SPECT in patients with AVM and compared the brain perfusion in the post-operative clinical courses. The acetazolamide brain perfusion SPECT was helpful in defining the prognosis of the patients with AVM. We describe 4 patients with AVM who had acetazolamide brain perfusion SPECT to examine the prognosis.

• 대한핵의학회지
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• 제23권2호
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• pp.165-173
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• 1989

1983년 1월 부터 1987년 12월까지 5년간 부산의 세곳 대학병원(부산의대, 고신의대, 인제의대)에서 병리조직학적으로 확진된 갑상선암 629예중 병력지 관찰이 가능하였던, 478예를 분석하여 1988년 보사부에서 발행한 Five Years' Report for Cancer Registry Programmme in Republic of Korea (1982 7. 1$\sim$1987. 6.30)의 발생빈도와 비교하였으며, 478예중 311예의 갑상선주사 소견을 분류하여 다음과 같은 결과를 얻었다. 1) 전체 악성암에 대한 갑상선암의 발생빈도는 2.54%(629/24.749)이었으며 이는 한국인에 있어서의 발생빈도와 거의 같았다(2.5%). 2) 여자에서 5배 이상 발생하여 (1 : 5.64) 이것 역시 한국인에서의 성별빈도와 매우 유사하였다(1 : 5.22). 3) 연령분포는 10세에서 91세까지로서 87.03%가 20세에서 59세 사이에 있었다. 4) 유두상암이 가장 흔하였고(78.24%),다음이 여포상암(14.44%) 그 다음이 미분화암(22.30%) 이었다. 5) 갑상선주사 소견상 대부분의 암은 solitary cold nodule을 보였다(82.96% : 258/311).

• 대한핵의학회지
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• 제23권2호
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• pp.231-236
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• 1989

Continuous ambulatory peritoneal dialysis (CAPD) is a well established method of treating end stage renal failure, and is commonly used as an alternative to hemodialysis. Several complications have been observed. These include catheter malfunction, abdominal and inguinal hernia, and peritonitis. A relatively frequent complication is swelling of external genitalia, due to bowel fluid passing through a patent processus vaginalis. Special diagnostic procedures are necessary to determine the nature of the abnormality and to guide the surgical correction. We reported two cases of patent processus vaginalis in patient on CAPD proved by radionuclide peritoneal scintiscan using Tc-99 m-tin colloid.