• Title/Summary/Keyword: ${131}^I$

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FLUX MONITORING OF 6.7 GHz METHANOL MASER TO SYSTEMATICALLY RESEARCH PERIODIC VARIATIONS USING THE HITACHI 32-m

  • SUGIYAMA, KOICHIRO;YONEKURA, YOSHINORI;MOTOGI, KAZUHITO;SAITO, YU;FUJISAWA, KENTA;ISHII, SHOTA;MOMOSE, MUNETAKE;HONMA, MAREKI;TAZAKI, FUMIE;TANAKA, KEI E.I.;HOSOKAWA, TAKASHI;UCHIYAMA, MIZUHO;INAYOSHI, KOHEI
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.129-131
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    • 2015
  • We have initiated single-dish monitoring observations of ~400 methanol maser sources at 6.7 GHz using the Hitachi 32-m radio telescope from December 2012 to systematically research periodic flux variations, which are observed in some methanol maser sources associated with high-mass (proto-)stars. In our monitoring, we have made daily monitoring, so that each source has been observed every nine days with an integration time of 5 min (typical $3{\sigma}$ detection sensitivities of 0.9 Jy). The monitoring observations help us statistically understand periodic flux variations with a period longer than 50 days. As an initial result, we present a new detection of periodic flux variations in the 6.7 GHz methanol maser source G 036.70+00.09. The period of the flux variations is ~53 days (~0.019 cycles $day^{-1}$), and seems to be stable over 9 cycles, at least until the middle of August 2014.

Influence of N-Fertilization on Growth , Yield and Nutrient Quality of Forage Job`s Tears [ Coix lachryma-jobi L. var. mayeur STAPF ] (청예 사초용 율무의 질소시비수준이 생육특성과 사료성분에 미치는 영향)

  • 안계주;권병선;김찬호
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.12 no.2
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    • pp.127-131
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    • 1992
  • To find out the optimum fertilizer levcl for Job's Tears, Seungju local cultivar, experiment with six fertilizer levels was conducted on the experimental field of forage crop in Sunchon National University from Apr. 1989 to Aug. 1990. The results obtained were summarized as follows: I .Raising nitrogen(N) application rate up to 13.5 kg/lOa increased dry matter yield linearly. However, at high N application rate, 18 kg/lOa, plants were too leafy and parts of leaves and lodging were decreased. so that dry matter yield was decreased.2. The optimum application rate of fertilizers turned out to be 13.5-6-6 kg/lOa of $P_2O_5$, $K_2O$. Content of crude protein, yield of fresh and dry matter were the highest and that of crude fiber such as NDF. ADF and cellulose were the lowest at this rate.

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A Study on Manufacturing and Experimental Techniques for the 1/5th Scale Model of Precast Concrete Large Panel Structure (프리캐스트 콘크리트 대형판 구조물의 1/5축소모델 제작 및 실험기법 연구)

  • 이한선;김상규
    • Magazine of the Korea Concrete Institute
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    • v.8 no.2
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    • pp.139-150
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    • 1996
  • The objective of this study is to provide the information on the manufacturing and exper- , ructures. imental techniques of small scale modeling of precast concrete(P.C.) large panel :-t The ad~~pted scale was one-fifth. 4 types of experiments were performed : nlaterial tests for model concrete and model reinforcement, compressive test of horizontal joint, shear test of vertical joint and cyclic static test of 2-story subassemblage structure. Based on the experimental results, the following conclusions are drawn : i 1) Model concrete had in general larger compressive strength than expected. (2) Model reinforcement showed less ductility if the annealing processes were performed without using vaccuum tube. 131 Failure niotles of horizontal and vertical joints were almost same for both prototype and model. But the strength of model appears to be higher than required by similitude law. (41 Hysteretic behavior of 1 /T, scale subassemblage model can be made quite similar to that of prototype if the ductility of model reinforcement and compressive strength of model concrete could be representative of those of prototype.

Variation in trn-L/trn-V and trn-F/trn-T spacer regions of cpDNA in Abies koreana Wilson and A. nephrolepis Traut./Maxim

  • Kormutak, A.;Hong, Y.-P.;Kwon, H.-Y.;Kim, C.-S.
    • Journal of Korean Society of Forest Science
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    • v.96 no.2
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    • pp.131-137
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    • 2007
  • The first evidence has been provided about the variation within trnL-trnV and trnF-trnT spacer regions of cpDNAs in Korean fir and Manchurian fir, revealed by PCR-RFLP analysis. Four cpDNA haplotypes have accordingly been recognized by being analyzed using the trnL-trnV/Tru11 primer-enzyme combination and 3 haplotypes using the trnF-trnT/TagI combination, which exhibited inter and intraspecific variation. A total of 6 cpDNA haplotypes were recognized by pooling the PCR-RFLP variants observed in both combinations. Haplotypes 2 and 3 were common for both species investigated, whereas haplotypes 1, 4, and 5 were detected only in Korean fir and haplotype 6 was detected only in Manchurian fir. Although haplotypes 2 and 3 were common in both species, haplotype 2 was major haplotype for Korean fir and haplotype 3 was one of the 2 major haplotypes for Manchurian fir. Restricted occurrence of haplotype 4 in Mt. Halla and haplotype 5 in Mt. Jiri of the Korean fir may represent the existence of geographic isolation by the sea between them. Diagnostic potential of individual haplotypes in discriminating between the two species as well as between their populations is discussed.

Relationship between Blood Mercury Level and Risk of Cardiovascular Diseases: Results from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) 2008-2009

  • Kim, Young-Nam;Kim, Young A;Yang, Ae-Ri;Lee, Bog-Hieu
    • Preventive Nutrition and Food Science
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    • v.19 no.4
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    • pp.333-342
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    • 2014
  • Limited epidemiologic data is available regarding the cardiovascular effects of mercury exposure. The purpose of this study was to determine the relationship between mercury exposure from fish consumption and cardiovascular disease in a nationally representative sample of Korean adults using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV 2008~2009). Survey logistic regression models accounting for the complex sampling were used to estimate the odds ratios (OR) adjusted for fish consumption frequency, age, education, individual annual income, household annual income, body mass index (BMI), waist circumference (WC), alcohol consumption status, and smoking status. The mean blood mercury level in the population was $5.44{\mu}g/L$. Trends toward increased blood mercury levels were seen for increased education level (P=0.0011), BMI (P<0.0001), WC (P<0.0001), and fish (i.e., anchovy) consumption frequency (P=0.0007). The unadjusted OR for hypertension in the highest blood mercury quartile was 1.450 [95% confidential interval (CI): 1.106~1.901] times higher than that of the lowest quartile. The fish consumption-adjusted OR for hypertension in the highest blood mercury quartile was 1.550 (95% CI: 1.131~2.123) times higher than that of the lowest quartile, and the OR for myocardial infarction or angina in the highest blood mercury quartile was 3.334 (95% CI: 1.338~8.308) times higher than that of the lowest quartile. No associations were observed between blood mercury levels and stroke. These findings suggest that mercury in the blood may be associated with an increased risk of hypertension and myocardial infarction or angina in the general Korean population.

A Study on the Flow Characteristics of Newtonian Fluid and Non-Newtonian Fluid in Dividing Tubes (분기관내 뉴턴 유체 및 비뉴턴 유체의 유동특성에 관한 연구)

  • Ha, O.N.;Chun, U.H.;Kim, G.;Lee, B.K.;Lee, H.S.;Yun, C.H.;Lee, J.I.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.6 no.6
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    • pp.113-131
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    • 1998
  • The objective of the present study is to investigate the characteristics of the dividing flow in the laminar flow region. Using glycerine water solution(wt43%) for Newtonian fluid and the polymer of viscoelastic fluid(500wppm) for non-Newtonian fluid, this research investigates the flow state of the dividing tube in steady laminar flow region of the two dimensional dividing tube by measuring the effect of Reynolds number, dividing angle, and the flow rate ratio on the loss coefficient. In T- and Y-type tubes, the loss coefficients of the Newtonian fluid decreases in constant rate when the Reynolds number is below 100. The effect of the flow rate ratio on the loss coefficients is negligible. But when the Reynolds number is over 100, the loss coefficient with various flow rate ratios approach an asymptotic value. The loss coefficient of the non-Newtonian fluid for different the Reynolds number shows the similar tendency of the Newtonian fluid. And when the Reynolds number is over 300, the loss coefficient is approximately 1.03 regardless of flow rate ratio or the dividing angle. The aspect ratio does hardly influence the reattachment length and the loss coefficient of both Newtonian and non Newtonian fluid. The loss coefficient decreases as the Reynolds number increases. The loss coefficient of Newtonian fluid is larger than that of non-Newtonian fluid.

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Use of $^{99m}TcO_4^-$ Salivary-Thyroid Ratio As a Test of Thyroid Function (갑상선스캔상에서 갑상선섭취율의 추정방법 : 타액선-갑상선계수율)

  • Yang, Woo-Jin;Chung, Soo-Kyo;Chun, Ki-Sung;Kim, Jong-Woo;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.21 no.2
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    • pp.151-154
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    • 1987
  • Total 114 patients were studied prospectively with radioiodine uptake (RAIU) and $^{99m}TcO_4^-$ thyroid scan to design a very simple, rapid and inexpensive method measuring the thyroid uptake on thyroid scan. After the RAIU was obtained at 24 hours after P.O. of $^{131}I$, Thyroid scan was performed at 20 minutes after LV. of $^{99m}TcO_4^-$ and the bilateral salivary glands were included in the scan field. Pinhole collimated and computer assisted gamma camera was used. Three regions of interest were set on each salivary gland and on the thyroid by automatic edge detection method. Mean counts per pixel were calculated for each ROI and the salivary-thyroid ratio (STR) was defined as; $$STR(%)=\frac{Mean\;counts\;per\;pixel\;of\;salivary\;glands\;(KC)}{Mean\;counts\;per\;pixel\;of\;thyroid\;gland\;(KC)}\times100$$ 114 cases consisted of 41 normal, 55 hyperthyroid and 18 hypothyroid patients and correlation between the STR and the RAID were evaluated in total and each group. The STR and the RAID showed reverse linear regression in 114 cases (r= -0.8, P=0) and closer correlation was shown in hyperthyroid group (r= -0_9, p=0). Mean STR in normal group was 47.6%. In predicting the RAID by STR, sensitivity and specificity were 88.3% and 64.9% in 114 cases and 95.3% and 83.3% in hyperthyroid group. It is recommended that the STR be used in place of the RAID giving same information at saving time, money and radiation exposure.

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Clinical Prognostic Score for Predicting Disease Remission with Differentiated Thyroid Cancers

  • Somboonporn, Charoonsak;Mangklabruks, Ampica;Thakkinstian, Ammarin;Vatanasapt, Patravoot;Nakaphun, Suwannee
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2805-2810
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    • 2016
  • Background: Differentiated thyroid cancer is the most common endocrine malignancy with a generally good prognosis. Knowing long-term outcomes of each patient helps management planning. The study was conducted to develop and validate a clinical prognostic score for predicting disease remission in patients with differentiated thyroid cancer based on patient, tumor and treatment factors. Materials and Methods: A retrospective cohort study of 1,217 differentiated thyroid cancer patients from two tertiary-care hospitals in the Northeast of Thailand was performed. Associations between potential clinical prognostic factors and remission were tested by Cox proportional-hazards analysis in 852 patients (development cohort). The prediction score was created by summation of score points weighted from regression coefficients of independent prognostic factors. Risks of disease remission were estimated and the derived score was then validated in the remaining 365 patients (validation cohort). Results: During the median follow-up time of 58 months, 648 (76.1%) patients in the development cohort had disease remission. Five independent prognostic factors were identified with corresponding score points: duration from thyroid surgery to $^{131}I$ treatment (0.721), distant metastasis at initial diagnosis (0.801), postoperative serum thyroglobulin level (0.535), anti-thyroglobulin antibodies positivity (0.546), and adequacy of serum TSH suppression (0.293). The total risk score for each patient was calculated and three categories of remission probability were proposed: ${\leq}1.628$ points (low risk, 83% remission), 1.629-1.816 points (intermediate risk, 87% remission), and ${\geq}1.817$ points (high risk, 93% remission). The concordance (C-index) was 0.761 (95% CI 0.754-0.767). Conclusions: The clinical prognostic scoring model developed to quantify the probability of disease remission can serve as a useful tool in personalized decision making regarding treatment in differentiated thyroid cancer patients.

Delayed presentation of aggravation of thyrotoxicosis after radioactive iodine therapy at Graves disease (그레이브스병에서 방사성요오드 치료 후 발생한 갑상샘항진증 악화의 지연된 발현)

  • Lee, Ji-Hyun;Na, Hyun-Jin;Park, Jin-Woo;Lee, Cheol-Ho;Han, Hyun-Jeong;Kim, Tae-Ho;Kim, Se-Hwa
    • Journal of Yeungnam Medical Science
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    • v.31 no.2
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    • pp.148-151
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    • 2014
  • Radioactive iodine (RAI) therapy is widely used for the treatment of Graves disease. After RAI therapy, 44% become hypothyroid and up to 28% remain hyperthyroid. The development of thyrotoxicosis after RAI therapy is believed to be mediated by 2 different mechanisms: a transient increased release of thyroid hormone due to radiation thyroiditis and the rare development of Graves disease due to the formation of antibodies to the thyroid-associated antigens released from the damaged follicular cells. A 55-year-old woman was hospitalized with severe headache, weight loss, and palpitation. She received a dose of 7 mCi of RAI (I-131) about 6 weeks earlier. Thyroid function test showed 7.98 ng/dL free T4, >8 ng/mL T3, < $0.08{\mu}IU/L$ thyroid stimulating hormone, and high titer thyroid stimulating immunoglobulin (TSI) (85.8 IU/L). She improved with propylthiouracil, propranolol, and steroid treatment. The TSI, however, was persistently elevated for 11 months.

Analysis of the Latest Trends of Radioisotope Using in RI-Biomics Fields (RI-Biomics분야 RI의 최신 동향 분석)

  • Jang, Sol-Ah;Yeom, Yu-Sun;Park, Tai-Jin;Hwang, Young Muk;Youn, Dol-Mi
    • Journal of Radiation Industry
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    • v.7 no.2_3
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    • pp.221-224
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    • 2013
  • RI-Biomics is a new compound word of radiation technology and Biomics related to the study of life. RI-Biomics is high radiation fusion technology by combining evaluation of pharmacokinetics in vivo (RI-ADME) of new drugs and medical materials using radioisotope and molecular imaging technology using nuclear medicine equipments. RI-Biomics fields are emerging with the increasing usage of radioisotopes (RI). In this paper, we investigated the latest trends of radioisotope using in RI-Biomics fields. The representative radioisotopes are $^{14}C$, $^3H$ and $^{32}P$ for the optimization and the selection of candidates in the development process of new drugs among the RI-Biomics fields. As shown in the status of accumulated income of radioisotopes, using amounts of radioisotopes are showing a tendency to increase every year. $^{14}C$ is 61.6% increase of accumulated income growth rate and $^3H$ increased by 58.8% and $^{32}P$ increased by 33.9% in 2012 compared to 2007. These isotopes are used in a variety of fields as using of $^{14}C$ for microdosing test, development of [$^3H$]cholesterol absorption inhibitors, study of [$^{131}I$]pyronaridine tetraphosphate for malaria therapy. These are going on in vivo test sucessfully. So, clinical research step is expected to begin soon. Therefore, usages of radioisotopes are necessary and need for the evaluation of pharmacokinetics, optimization and the selection of new drug candidates in the development process of new drugs among the RI-Biomics fields. So, using of radioisotopes is predict to increase continuously except for primarily used $^{14}C$, $^3H$.