• Title/Summary/Keyword: ${\pi}$-type

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Gingival crevicular fluid CSF-1 and IL-34 levels in patients with stage III grade C periodontitis and uncontrolled type 2 diabetes mellitus

  • Ahu Dikilitas;Fatih Karaaslan;Sehrazat Evirgen;Abdullah Seckin Ertugrul
    • Journal of Periodontal and Implant Science
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    • v.52 no.6
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    • pp.455-465
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    • 2022
  • Purpose: Periodontal diseases are inflammatory conditions that alter the host's response to microbial pathogens. Type 2 diabetes mellitus (T2DM) is a complex disease that affects the incidence and severity of periodontal diseases. This study investigated the gingival crevicular fluid (GCF) levels of colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34) in patients with stage III grade C periodontitis (SIII-GC-P) and stage III grade C periodontitis with uncontrolled type 2 diabetes (SIII-GC-PD). Methods: In total, 72 individuals, including 24 periodontally healthy (PH), 24 SIII-GC-P, and 24 SIII-GC-PD patients, were recruited for this study. Periodontitis patients (stage III) had interdental attachment loss (AL) of 5 mm or more, probing depth (PD) of 6 mm or more, radiographic bone loss advancing to the middle or apical part of the root, and tooth loss (<5) due to periodontal disease. Radiographic bone loss in the teeth was also evaluated; grade C periodontitis was defined as a ratio of the percentage of root bone loss to age greater than 1.0. The plaque index (PI), gingival index (GI), presence of bleeding on probing (BOP), PD, and clinical AL were used for clinical periodontal assessments. GCF samples were obtained and analyzed using an enzyme-linked immunosorbent assay. Results: All clinical parameters-PD, AL, GI, BOP, and PI-were significantly higher in the SIII-GC-PD group than in the PH and SIII-GC-P groups for both the full mouth and each sampling site (P<0.05). The total IL-34 and CSF-1 levels were significantly higher in the SIII-GC-PD group than in the PH and SIII-GC-P groups (P<0.05), and there were significant differences between the periodontitis groups (P<0.05). Conclusions: These findings suggest that IL-34 and CSF-1 expression increases in patients with SIII-GC-PD. CSF-1 was associated with the inflammatory status of periodontal tissues and T2DM, while IL-34 was associated only with T2DM.

The Deposition Characterization of DLPC Lipid Membrane by Moving Wall Type LB Methode (Moving Wall형 LB법에 의해서 제작된 DLPC 지질막의 누적특성)

  • 정용호;이우선;김남오;이경섭
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1997.04a
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    • pp.342-345
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    • 1997
  • We fabricated the sample of u1tra thin lipid membrane(L-${\alpha}$-DLPC ) by LB methode. The $\pi$-A isotherm of the DLPC was measured at the air-water interface varying with the compressing speed and amounts of solutions for spreading. For good property of lipid monolayer film, it was necessary for the lower speed of compressing, and 40${\mu}\ell$ of solutions for spreading. The molecular arrangement of deposited films were evaluated by measuring the absorption, transmitance and intensity with the UV spectrophotometer. The Y-type multilayers prepared at 50mN/m showed weaker than Z-type. So we found building-up of structurally high quality LB films is essential to study properties of the films and to get reproducible data.

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The Mold Close and Open Control of Injection Molding Machine Using Fuzzy Algorithm

  • Park, Jin-Hyun;Lee, Young-Kwan;Kim, Hun-Mo
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.575-579
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    • 2005
  • In this paper, the development of an IMM(Injection Molding Machine) controller is discussed. Presently, the Mold Close and Open Control Method of a toggle-type IMM is open-loop control. Through the development, a PC based control system was built instead of an existing controller and a closed-loop control replaced the previous control method by using PC based PLC. To control the nonlinear system of toggle type clamping unit, a fuzzy PI control algorithm was selected and it was programmed by an IL(Instruction List) and a LD(Ladder Diagram) on a PC based PLC. The application of fuzzy algorithm as the control method was also considered to change a control object like a mold replacement or an additional apparatus. For the development of an IMM controller, PC based PLC of PCI card type, distributed I/O modules with CANopen and Industrial PC and HMI (Human Machine Interface) software were used.

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The Action of Phospholipids and Effect of Medium Composition During Sexual Differentiation Process in Heterobasidiomycetous Yeast Rhodospotidium toruloides. (이담자균 효모의 성분화과정중 인지질의 작용과 배지조성의 제한이 성분화에 미치는 영향)

  • 정영기;강원대;남수완
    • Journal of Life Science
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    • v.6 no.3
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    • pp.165-170
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    • 1996
  • The action of phospholipid on the rhodotorucine A(RH.A) acceptance by heterbasidiomyceteous yeast Rhodosporidium toruloides mating type a cells and the effect of medium composition during sexual differentiation were investigated. Activation of trigger peptidase(TPase)was very sensitive to the originated phospholipid from R. toruloides and was more sensitive to phospholipid liposome made up of phospholipi. Phospholopod present on the membrance of mating type a cells consists of phospatidylglycerol(PG), phosphatidylethanolamine(PE), phospatidylcholine(PC), phospatidylinositol(PI), and phosphatidylserine(PS) of 12.9, suprisingly 45.4, 11.0, and 13.9%, respectively. As the result of using C-1 and N-1 mediums which limited C and N sources capable of inhibiting the synthesis of phospholipid, it resulted inhibiting sexual dlfferentiation and production of Rh.A from mating type Acells.

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Design of a optimum structure for Ultrasonic Linear Motor using a travelling wave (진행파를 이용한 직선형 초음파 모터의 최적구조 설계)

  • 김연보;한우석;노용래
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.13 no.4
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    • pp.280-285
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    • 2000
  • The conventional ultrasonic linear motors developed so far utilize a standing wave and are of a pi-type or a hybrid transducer type structure. Traveling wave type bi-direction linear motors have not been developed yet. This paper describes design of a new bi-directional ultrasonic linear motor working by means of a traveling wave. With the finite element method we design and verify validity of the new structure. And we determine its optimal structure size of design variables material and boundary conditions for proper generation of the traveling wave.

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Modelling of an Automotive Block Type Thermostatic Expansion Valve (자동차용 블록식 온도감응 팽창밸브의 모델링)

  • Won, Sung-Pil
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.23 no.4
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    • pp.251-258
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    • 2011
  • The objective of this study is to propose two empirical correlations to predict the mass flow rate through an automotive block type thermostatic expansion valve and then to evaluate the correlations. The first correlation is deduced by modifying the basic equation of the orifice meter for the mass flow rate and the second correlation is deduced by using the Buckingham's ${\pi}$ theorem. The first correlation showed very good agreement on the measured data for R134a, given by Monforte. Average relative deviation and standard deviation of it are 2.5% and 1.6%, respectively. The second correlation agreed on the same measured data with a little greater deviations. The two correlations may apply to common expansion valves which have different geometrical sizes of the same shape.

Evaporator Superheat Control of a Multi-type Air-conditioning/Refrigeration System (멀티형 공조/냉동시스템의 증발기 과열도 제어)

  • Kim, Tae-Sub;Hong, Keum-Shik;Sohn, Hyun-Chul
    • Proceedings of the KSME Conference
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    • 2001.06b
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    • pp.712-717
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    • 2001
  • This paper investigates the control problem of evaporator superheat, i.e., the difference between the temperature of the refrigerant at the entrance region of an evaporator and that at the exit region, for multi-type air-conditioning/refrigeration systems. Mathematical equations describing the characteristics of compressor, condenser, evaporator, and electronic expansion valve are first derived. Then, the transfer functions from the current input of the electronic expansion valve to wall temperatures of evaporator tube at two-phase region and superheated region, respectively, are derived. The stability and performance of the closed loop system with a PI controller are analyzed by Nyquist stability criterion. Simulation results are provided.

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Auto-tunning of a FLC using Neural Networks (신경망을 이용한 서보제어기의 자동조정)

  • Yeon, Jae-Kuen;Yum, Jin-Ho;Nam, Hyun-Do
    • Proceedings of the KIEE Conference
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    • 1996.07b
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    • pp.1034-1036
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    • 1996
  • In this paper, an adaptive fuzzy logic controller is presented for auto-tunning of the scaling factors by using learning capability of neural networks. The proposed scheme consists of the FLC which includes the PI-type FLC and PD-type FLC in parallel form and the neural network which learns scale factors of FLC. Computer simulations were performed to illustrate the effectiveness of a proposed scheme. A proposed FLC controller was applied to the second order system and velocity control of the brushless DC motors. For the design of the FLC, tracking error, change of error, and acceleration error are selected as input variables of the FLC and three seal e factors were used in the parallel-type FLC. This scheme can be used to reduce the difficulty in the selection of the scale factors.

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The Deposition Characterization of DLPC Lipid Membrane Fabricated by Moving wall Type LB Method (Moving wall형 LB법에 의하여 제작된 DLPC 지질막의 누적특성)

  • 이우선;최창주;정용호;김남오;이경섭;장의구;김태성
    • Electrical & Electronic Materials
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    • v.10 no.6
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    • pp.548-554
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    • 1997
  • We fabricated the sample of ultra thin lipid membrane(L-$\alpha$-DLPC) by LB method. The $\pi$-A isotherm of the DLPC was measured at the air-water interface varying with the compressing speed and amounts of solutions for spreading. For the good property of lipid monolayer film, it was necessary to prepare at the lower speed of compressing, with an appropriate volume of solutions for spreading. Absorption, transmitance and intensity with the UV spectrophotometer were measured. The Z-type multilayers showed good characteristics better than Y-type. So we found building-up of structurally high quality LB films is essential to study properties of the films and to get reproducible data.

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Impact of scaling and root planing on C-reactive protein levels in gingival crevicular fluid and serum in chronic periodontitis patients with or without diabetes mellitus

  • Mohan, Mahendra;Jhingran, Rajesh;Bains, Vivek Kumar;Gupta, Vivek;Madan, Rohit;Rizvi, Iram;Mani, Kanchan
    • Journal of Periodontal and Implant Science
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    • v.44 no.4
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    • pp.158-168
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    • 2014
  • Purpose: The present study was conducted to evaluate the impact of scaling and root planing (SRP) on the C-reactive protein (CRP) levels of gingival crevicular fluid (GCF) and serum in chronic periodontitis patients with type 2 diabetes mellitus (T2DM-CP) or without type 2 diabetes mellitus (NDM-CP). Methods: Forty-eight human participants were divided into two groups: an experimental (T2DM-CP) group (group I, n=24) comprising chronic periodontitis patients with random blood sugar ${\geq}200mg/dL$ and type 2 diabetes mellitus, and control (NDM-CP) group (group II, n=24) of those with chronic periodontitis and random blood sugar <200 without T2DM for the study. All subjects underwent nonsurgical periodontal therapy (NSPT) including complete SRP and subgingival debridement. Periodontal health parameters, plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), GCF volume (GCF vol), GCF-CRP, random blood glucose (RBS), glycated hemoglobin, and systemic inflammatory markers, serum CRP, total leukocyte count (TLC), neutrophil count (Neutr) and lymphocyte count (Lymph), were evaluated at baseline, 1 month, and 3 months after SRP. Results: NSPT resulted in statistically significant improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum as well as GCF of both groups I and II. The mean improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum and GCF was greater in group I than group II after NSPT. There was nonsignificant increase in GCF-CRP, TLC, Lymph, and RBS, and a significant increase in Neutr and Serum CRP in group II at 1 month. The Serum CRP level of 20 out of 24 group II patients had also increased at 1 month. Conclusions: The CRP levels in both GCF and serum were higher in T2DM-CP patients than in NDM-CP patients. Although there was a significant improvement in both the groups, greater improvement was observed in both GCF and serum samples of T2DM-CP patients.