• Title/Summary/Keyword: ${\alpha}_s$-method

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A Comparison of EEG Response between TV Advertisements focused on Information Transfer and Emotional Reaction (정보전달형 TV광고와 감성유발형 TV광고의 뇌파반응 비교)

  • Kim, Jeong-Ryong;Park, Ji-Su;Kim, Mi-Suk
    • Journal of the Ergonomics Society of Korea
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    • v.22 no.4
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    • pp.1-13
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    • 2003
  • This study has investigated psychological responses to various TV advertisements by using EEG(electroencephalogram). In particular, it was assumed that the brain wave would show different patterns depending upon the style of the advertisement that could be categorized into two such as 'information transfer' type and 'emotional reaction' type. Ten healthy males participated in the experiment. EEG signal was extracted from six lobes such as right and left frontal, right and left occipital, right and left temporal while the subjects were watching TV advertisements. Alpha and beta relative power spectrum, and beta/alpha parameter were calculated to compare two kinds of advertisement each other. Additionally, subjective questionnaire was used to examine subject's response by using adjective words and preference test. In result, significant differences were found in left frontal and right occipital lobe in terms of beta/alpha between two different advertisements. And, subjects showed different preference between two advertisements. It was shown that the current method could analyze the brain reaction to advertisement quantitatively, that presented the possibility of using it to marketing research.

Status of High Risk Group Fabry Disease Screening in Korea by Measuring Globotriacocylceramide in Body Fluid using Electrospray-MS/MS (탠덤매스에의한 체액 중 Globotriaocylceramide(Gb-3)의 측정을 이용한 한국인 고 위험도군에서의 파브리병 스크리닝)

  • Yoon, Hye-Ran
    • YAKHAK HOEJI
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    • v.55 no.1
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    • pp.56-63
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    • 2011
  • Fabry disease (FD) is an X-linked inborn error of glycoshpingolipid metabolism resulting from mutation in the enzyme ${\alpha}$-galactosidase A gene. The disease is an X-linked lipid storage disorder and the lack of ${\alpha}$-Gal A causes an intracellular accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb-3). Measurement of Gb-3 in plasma has clinical importance for monitoring after enzyme replacement therapy for confirmed FD patients. Using electrospray ionization MS/MS we had developed, a simple, rapid, and highly sensitive analytical method for Gb-3 in plasma was used for the purpose of screening FD among high risk groups in Korean population. To date, no comprehensive results for FD screening have been performed and reported in Korea. We screened 1,100 outpatients from 13 hospitals (including clinics) to assess the incidence of FD among patients in high risk groups. For patients with borderline level amount of Gb-3, we repeated Gb-3 or performing complementary or confirmative assay with ${\alpha}$-Gal A activity and DNA mutaion analysis for confirmation diagnosis. Of 1,100 we diagnosed 3 FD with 2 classical type and 1 carrier (0.27%).

Non-isothermal Decomposition Kinetics of a New High-energy Organic Potassium Salt: K(DNDZ)

  • Xu, Kangzhen;Zhao, Fengqi;Song, Jirong;Ren, Xiaolei;Gao, Hongxu;Xu, Siyu;Hu, Rongzu
    • Bulletin of the Korean Chemical Society
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    • v.30 no.10
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    • pp.2259-2264
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    • 2009
  • A new high-energy organic potassium salt, 2-(dinitromethylene)-1,3-diazepentane potassium salt K(DNDZ), was synthesized by reacting of 2-(dinitromethylene)-1,3-diazepentane (DNDZ) and potassium hydroxide. The thermal behavior and non-isothermal decomposition kinetics of K(DNDZ) were studied with DSC, TG/DTG methods. The kinetic equation is $\frac{d{\alpha}}{dT}$ = $\frac{10^{13.92}}{\beta}$3(1 - $\alpha$[-ln(1 - $\alpha$)]$^{\frac{2}{3}}$ exp(-1.52 ${\times}\;10^5$ / RT). The critical temperature of thermal explosion of K(DNDZ) is $208.63\;{^{\circ}C}$. The specific heat capacity of K(DNDZ) was determined with a micro-DSC method, and the molar heat capacity is 224.63 J $mol^{-1}\;K^{-1}$ at 298.15 K. Adiabatic time-to-explosion of K(DNDZ) obtained is 157.96 s.

Radiative transfer In General grid: RIG

  • Lee, Seok-Ho;Park, Young-Sun;Lee, Jeong-Eun
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.1
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    • pp.82.1-82.1
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    • 2011
  • We present a new code for solving non-LTE radiative transfer problems in a general grid (RIG). RIG develops from RATRAN code (Hogerheijde & van der Tak 2000) using the Accelerated Monte-Carlo method, and it can cope with line overlap effect among multiple molecular and atomic species. In this algorithm we make grids in arbitrary coordinates adequate to the problem, but, on the other hand, photons propagate in the Cartesian coordinates. For spherical, cylindrical and other well defined coordinate, the problem of tracing photon's path reduces to solving simple quadratic equations. For example, the outflow in the star formation have high dynamic range in scales from a few AU to ~ 0.1 pc and have also cylindrical symmetry. So, we have used (r, ${\alpha}$) coordinate system, where r is the distance from the origin and ${\alpha}$ is z/ R2 in the cylindrical coordinate of (R,z). The (r, ${\alpha}$) coordinate realizes the density - power function of r - and temperature distributions of the problems with smaller numbers of grid than the cylindrical coordinate does, and the former consumes less time to solve the problems than the latter.

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Effect of Water Extract from Artemisiae Argi Folium on Mouse Macrophage Stimulated by LPS (Lipopolysaccharide로 활성화된 마우스 대식세포에서 애엽(艾葉) 물추출물의 면역활성 연구)

  • Park, Wan-Su
    • The Korea Journal of Herbology
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    • v.24 no.1
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    • pp.151-157
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    • 2009
  • Objectives : The purpose of this study is to investigate the effect of Water Extract from Artemisiae Argi Folium (WAAF) on mouse macrophage Raw 264.7 cells stimulated by lipopolysaccharide (LPS). Methods : Cell viabilities were measured by MTT assay. And the intracellular productions of hydrogen peroxide (H2O2) were measured by dihydrorhodamine 123 assay. TNF-$\alpha$ and IL-6 production from Raw 264.7 were measured by ELISA method. Results : The results of the experiment are as follows. 1. WAAF significantly increased the cell viability compared to the control group (treated with LPS only) at the concentrations of 10, 50, 100, 200, 400 ug/mL. 2. WAAF significantly increased the intracellular production of H2O2 compared to the control group at the concentrations of 50, 100, 200 ug/mL. 3. WAAF significantly decreased the production of TNF-$\alpha$ compared to the control group at the concentrations of 100, 200 ug/mL. 4. WAAF significantly decreased the production of IL-6 compared to the control group at the concentrations of 50, 100, 200 ug/mL. Conclusions : WAAF could be supposed to have the immune-modulating activity related with the macrophage's immunoactivity.

An Methodology Research of the Quality of Life of the Allogenic Bone Marrow Transplantation Survivors (동종골수이식 환자의 삶의 질 측정도구 개발)

  • Lee, Sun-Gyo
    • Asian Oncology Nursing
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    • v.1 no.1
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    • pp.18-31
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    • 2001
  • This Research was designed to develop an instrument that can be used for measuring and analysing the degree of the quality of life of the Allogenic bone marrow transplantation survivors and to provide basic data to help them attain a better quality of life. The subjects of this study were a total of 101 people who were undergone Allogenic bone marrow transplantation and were over 100 days after transplantation. Data were collected during the period from September 3 to December 2. 2000. In Developing this instrument, the researcher established a conceptual framework based on the result of previous research, interview of patients and medical staff and researcher's experience. The scale for this instrument consisted of 51 items. Responses were obtained from the respondents through a self reporting method and each item had a possible score of 5. The collected data were analyzed using the SPSS program. The reliability of the scale was tested by Cronbach‘s alpha. For the examination of the component factors of the measuring instruments, factor analysis method was used. Examination of the difference in the quality of life as related to demographic variables was done using t-test, analysis of variance(ANOVA). For the examination of the major variables influencing the quality of life, Pearson's Correlations was used. The results were as follows: (1) The reliability of the instrument was 0.90 (Cronbach's alpha) (2) The validity of the instrument was tested by factor analysis. The result of the factor analysis of the 51 items is making up the instruments were classified into the following factor; emotional state, Interpersonal problem, physical problem, spiritual state, social problem, decrease of physical energy, physical problem-eye, physical problem-skin and mucosa, health awareness, elimination problem, worry about health, financial problem, sexual problem. (3) Demographic variables related to quality of life is the time after transplantation. GVHD experience, lose of job. Age at the transplantation, diagnosis, type of the transplantation, marital status, monthly income, educational background, sex, religion are not related to the quality of life.

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Transmission of Substituent Effects through 5-Membered Heteroaromatic Rings

  • Lee, Ik Hun;Ri, Sun Gi;Kim, Chang Gon;Jeong, Dong Su;Kim, Chan Gyeong
    • Bulletin of the Korean Chemical Society
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    • v.21 no.9
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    • pp.882-890
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    • 2000
  • Ab initio calculations are carried out on protonation equilibria of 5-memberedheteroaromatic aldehydes (5MHAs;heteroatom Y = NH, O, PH,and S and substituentZ = NH2, OCH3, SCH3, CH3, H, Cl, CHO, CN,NO2) at the $MP2}6-31G*$ level. Naturalbond orbital (NBO) analyses show that the optimal localized natural Lewis structures of the protonated aldehydes,(P), are ortho (C3) protonated (for Y = O, PH and S) and N-pro-tonated (for Y = NH) forms in contrast to the standard structural Lewis formula for aldehydes, (R). The delo-calizability of ${\pilone}-pairon$ the heteroatom $(n{\pi}(Y))$ is in the order Y = NH > O > S > PH. The transmission efficiency of (Z) substituent effects to the carbonyl moiety run parallel to the delocalizability of $n{\pi}(Y)$ for R,but is dominantly influenced by the cationic charge on $C{\alpha}(C{\alpha}+)$ for P, which is in the reverse order of thede-localizability of $n{\pi}(Y).$ The Hammett ${\rho}values$ for variation of Z in the protonation are determined by the dif-ference in the transmission efficiencies between Pand R stateat simple interpretation of their magnitude is not warranted. However,the magnitude of the gas-phase ${\rho}z+$ values decreases as the level ofcomputation is raised from RHF/3-21G* to RHF/6-31G* and to $MP2}6-31G*$ but increases again at the MP4SDQ/6-31G* level. Further decrease occurs when solvent effect (water) is accounted for by the SCRF method. Comparison of the SCRF ${\rho}z+values$ with those determined in the aqueous acid solution for Y = S and CHCH shows inadequacy of accounting for the solvent effects on the ${\rho}values$ by a continuum model. It is noteworthy that semiempirical calculations, especially theAM1 method, give even lower magnitude of the gas-phase ${\rho}values.

A Study for Construct Validity and Reliability of the Sensory Processing Scale for Children (SPS-C) (아동감각처리척도(Sensory Processing Scale for Children: SPS-C)의 구성타당도 및 신뢰도 연구)

  • Kim, Kyeong-Mi;Shin, Hyeon-Hui
    • The Journal of Korean Academy of Sensory Integration
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    • v.14 no.2
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    • pp.11-21
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    • 2016
  • Objective : The purpose of the study is to examine the construct validity and internal consistency of the Sensory Processing Scale for Children (SPS-C). Method : 117 participants who are aged 3 to 5 years old has been evaluated by the Sensory Processing Scale for Children (SPS-C) for this study and the period is from November 2014 to June 2016. Statistics used for data analysis is factor analysis for construct validity and Cronbach's alpha for internal consistency. Results : In the factor analysis, the items in auditory, visual, and tactile showed a high factor loading, respectively. The items in vestibular and proprioceptive were overlapped. For internal consistency, Cronbach's alpha was .728 for whole scale which is high level. And Cronbach's alpha of each factor was range within .326~.636. Conclusion : The results of the psychometric test in this study evidence that the SPS-C is valid and reliable to be utilized. Further study need to examine various validities and reliabilities as well as standardization.

Relationship of Speciality of Personal Trainer, PT Satisfaction and Exercise Adherence (퍼스널트레이너의 전문성이 회원의 PT만족 및 운동지속에 미치는 영향)

  • Kim, Kyong-Sik
    • The Journal of the Korea Contents Association
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    • v.14 no.10
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    • pp.298-305
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    • 2014
  • This study is to analyze the relationship of speciality of personal trainer, PT satisfaction and exercise adherence. To accomplish this goal, this study sampled 240 members of sports facilities of Seoul utilizing purposive sampling method in 2013. But this study finally used 219 samples in data analysis. Validity and reliability of instruments tested by expert meetings and reliability analysis. Chronbach's ${\alpha}$ is over .697. Data analysis is SEM using AMOS 18.0. Conclusions are the followings. Firstly, speciality of personal trainer influence on PT satisfaction of members. Secondly, speciality of personal trainer influence on exercise adherence. Thirdly, PT satisfaction influence on exercise adherence. Fourthly, PT satisfaction have not a mediating role between speciality and exercise adherence.

A Study on the Reliability Assessment of Sasang Constitution Questionnaire Developed by KIOM for Japanese (일본인 대상자를 통해 살펴본 KIOM 체질 설문지의 신뢰도 평가)

  • Yoo, Jong-Hyang;Jang, Eun-Su;Kim, Yun-Yung;Park, Ki-Hyun;Lee, Si-Woo
    • Journal of Sasang Constitutional Medicine
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    • v.24 no.2
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    • pp.8-18
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    • 2012
  • 1. Objectives : This study aimed to assessing the reliability of questionnaire for Japanese as one of method to diagnose Sasang Constitution and evaluating the possibility of applying domestic questionnaire to foreign site. 2. Methods : A cross-sectional survey approved by IRB (Independent Review Board) at Tohoku University was performed for 119 participants with informed consent at a particular city in Japan using self-reported questionnaires developed by KIOM (Korea Institute of Oriental Medicine). Among the entire samples, 112 were retested. The test-retest reliability was assessed by Kappa for normal variables and internal consistency was evaluated by Cronbach's alpha. 3. Results : Four of 77 questions are impossible to calculate consistency owing to unsymmetric matrix between primary reply and secondary one. Seventeen of them (22%) showed 0.4 or below in Kappa, 56 were ranged from 0.4 to 0.8 and no question marked 0.8 or over. Internal consistency was possibly checked for several questions about character, digestion, sweat, excrement, urine, cold-heat pattern. Cronbach's alpha for questions except urine and cold-heat pattern was over 0.6 4. Conclusions : On the basis of Kappa value by two self reported questionnaire, 72.7% of questions showed 0.4 or over so that reliability were highly secured. And other questions except for urine and heat-cold pattern marked 0.6 or over in order that internal consistency was also successfully maintained. Accordingly, when subsequently applying KIOM questionnaire to foreign site, domestic questionnaire should be properly adjusted in social and cultural background, lifestyle, etc.